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2BQZ
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE HUMAN HISTONE METHYLTRANSFERASE PR-SET7 (ALSO KNOWN AS SET8)
分子名称:SET8 PROTEIN, HISTONE H4, S-ADENOSYL-L-HOMOCYSTEINE
著者Xiao, B., Jing, C., Kelly, G., Walker, P.A., Muskett, F.W., Frenkiel, T.A., Martin, S.R., Sarma, K., Reinberg, D., Gamblin, S.J., Wilson, J.R.
登録日2005-04-28
公開日2005-06-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Specificity and Mechanism of the Histone Methyltransferase Pr-Set7
Genes Dev., 19, 2005
1PHP
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STRUCTURE OF THE ADP COMPLEX OF THE 3-PHOSPHOGLYCERATE KINASE FROM BACILLUS STEAROTHERMOPHILUS AT 1.65 ANGSTROMS
分子名称:3-PHOSPHOGLYCERATE KINASE, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
著者Davies, G.J., Watson, H.C.
登録日1994-04-12
公開日1994-06-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of the ADP complex of the 3-phosphoglycerate kinase from Bacillus stearothermophilus at 1.65 A.
Acta Crystallogr.,Sect.D, 50, 1994
1TX4
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RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX
分子名称:P50-RHOGAP, TRANSFORMING PROTEIN RHOA, MAGNESIUM ION, ...
著者Rittinger, K., Walker, P.A., Smerdon, S.J., Gamblin, S.J.
登録日1997-07-29
公開日1998-09-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue.
Nature, 389, 1997
1K0R
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS NUSA
分子名称:NusA, SULFATE ION
著者Gopal, B., Haire, L.F., Gamblin, S.J., Dodson, E.J., Lane, A.N., Papavinasasundaram, K.G., Colston, M.J., Dodson, G., TB Structural Genomics Consortium (TBSGC)
登録日2001-09-20
公開日2001-12-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the transcription elongation/anti-termination factor NusA from Mycobacterium tuberculosis at 1.7 A resolution.
J.Mol.Biol., 314, 2001
1MXE
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STRUCTURE OF THE COMPLEX OF CALMODULIN WITH THE TARGET SEQUENCE OF CAMKI
分子名称:Calmodulin, Target Sequence of rat Calmodulin-Dependent Protein Kinase I, CALCIUM ION
著者Clapperton, J.A., Martin, S.R., Smerdon, S.J., Gamblin, S.J., Bayley, P.M.
登録日2002-10-02
公開日2002-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the Complex of Calmodulin with the Target Sequence of Calmodulin-Dependent Protein Kinase I: Studies of the Kinase Activation Mechanism
Biochemistry, 41, 2002
1SML
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METALLO BETA LACTAMASE L1 FROM STENOTROPHOMONAS MALTOPHILIA
分子名称:PROTEIN (PENICILLINASE), ZINC ION
著者Ullah, J.H., Walsh, T.R., Taylor, I.A., Emery, D.C., Verma, C.S., Gamblin, S.J., Spencer, J.
登録日1998-09-22
公開日1999-09-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia at 1.7 A resolution.
J.Mol.Biol., 284, 1998
2AIO
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METALLO BETA LACTAMASE L1 FROM STENOTROPHOMONAS MALTOPHILIA COMPLEXED WITH HYDROLYZED MOXALACTAM
分子名称:Metallo-beta-lactamase L1, ZINC ION, SULFATE ION, ...
著者Spencer, J., Read, J., Sessions, R.B., Howell, S., Blackburn, G.M., Gamblin, S.J.
登録日2005-07-30
公開日2005-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Antibiotic Recognition by Binuclear Metallo-beta-Lactamases Revealed by X-ray Crystallography
J.Am.Chem.Soc., 127, 2005
1O9S
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE HUMAN HISTONE METHYLTRANSFERASE SET7/9
分子名称:HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC, GENE FRAGMENT FOR HISTONE H3, ...
著者Xiao, B., Jing, C., Wilson, J.R., Walker, P.A., Vasisht, N., Kelly, G., Howell, S., Taylor, I.A., Blackburn, G.M., Gamblin, S.J.
登録日2002-12-18
公開日2003-02-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and Catalytic Mechanism of the Human Histone Methyltransferase Set7/9
Nature, 421, 2003
1XQH
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE METHYLTRANSFERASE SET9 (ALSO KNOWN AS SET7/9) WITH A P53 PEPTIDE AND SAH
分子名称:Histone-lysine N-methyltransferase, H3 lysine-4 specific, 9-mer peptide from tumor protein p53, ...
著者Chuikov, S., Kurash, J.K., Wilson, J.R., Xiao, B., Justin, N., Ivanov, G.S., McKinney, K., Tempst, P., Prives, C., Gamblin, S.J., Barlev, N.A., Reinberg, D.
登録日2004-10-12
公開日2004-11-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Regulation of p53 activity through lysine methylation
Nature, 432, 2004
2YP5
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3SLN
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP9
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HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3SLN
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
1OW3
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CRYSTAL STRUCTURE OF RHOA.GDP.MGF3-IN COMPLEX WITH RHOGAP
分子名称:Rho-GTPase-activating protein 1, Transforming protein RhoA, MAGNESIUM ION, ...
著者Graham, D.L., Lowe, P.N., Grime, G.W., Marsh, M., Rittinger, K., Smerdon, S.J., Gamblin, S.J., Eccleston, J.F.
登録日2003-03-28
公開日2003-05-06
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer
Chem.Biol., 9, 2002
2YP8
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HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE 6SLN
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
3IIW
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CRYSTAL STRUCTURE OF EED IN COMPLEX WITH A TRIMETHYLATED HISTONE H3K27 PEPTIDE
分子名称:Polycomb protein EED, Histone H3 peptide
著者Justin, N., Sharpe, M.L., Martin, S., Taylor, W.R., De Marco, V., Gamblin, S.J.
登録日2009-08-03
公開日2009-09-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
4CPY
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STRUCTURE OF THE NEURAMINIDASE FROM THE B/LYON/CHU/15.216/2011 VIRUS IN COMPLEX WITH OSELTAMIVIR
分子名称:NEURAMINIDASE, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Vachieri, S.G., Collins, P.J., Escuret, V., Casalegno, J.S., Cattle, N., Ferraris, O., Sabatier, M., Frobert, E., Caro, V., Skehel, J.J., Gamblin, S.J., Valla, F., Valette, M., Ottmann, M., McCauley, J.W., Daniels, R.S., Lina, B.
登録日2014-02-09
公開日2014-05-14
最終更新日2014-10-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Novel I221 L Substitution in Neuraminidase Confers High Level Resistance to Oseltamivir in Influenza B Viruses.
J.Infect.Dis., 210, 2014
2YP4
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE LSTC
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP7
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HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
6HKG
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STRUCTURE OF FISW84 FAB FRAGMENT
分子名称:FISW84 Fab Fragment Heavy Chain, FISW84 Fab Fragment Light Chain, SULFATE ION
著者Benton, D.J., Rosenthal, P.B.
登録日2018-09-06
公開日2018-09-26
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Influenza hemagglutinin membrane anchor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2YP3
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE 6SLN
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
1VPS
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POLYOMAVIRUS VP1 PENTAMER COMPLEXED WITH A DISIALYLATED HEXASACCHARIDE
分子名称:POLYOMAVIRUS VP1 PENTAMER, O-SIALIC ACID, BETA-D-GALACTOSE, ...
著者Stehle, T., Harrison, S.C.
登録日1997-03-07
公開日1997-05-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-resolution structure of a polyomavirus VP1-oligosaccharide complex: implications for assembly and receptor binding.
Embo J., 16, 1997
2YP2
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
3CKZ
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N1 NEURAMINIDASE H274Y + ZANAMIVIR
分子名称:Neuraminidase, CALCIUM ION, ZANAMIVIR
著者Colllins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.
登録日2008-03-18
公開日2008-05-20
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
4B7R
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H1N1 2009 PANDEMIC INFLUENZA VIRUS: RESISTANCE OF THE I223R NEURAMINIDASE MUTANT EXPLAINED BY KINETIC AND STRUCTURAL ANALYSIS
分子名称:NEURAMINIDASE, CALCIUM ION, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, ...
著者Liu, J., van der Vries, E., Vachieri, S.G., Xiong, X., Collins, P.J., Walker, P.A., Haire, L.F., Hay, A.J., Schutten, M., Osterhaus, A.D.M.E., Martin, S.R., Boucher, C.A.B., Skehel, J.J., Gamblin, S.J.
登録日2012-08-21
公開日2012-10-03
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
4BH4
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HAEMAGGLUTININ FROM A TRANSMISSIBLE MUTANT H5 INFLUENZA VIRUS IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3'-SLN
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Xiong, X., Coombs, P.J., Martin, S.R., Liu, J., Xiao, H., McCauley, J.W., Locher, K., Walker, P.A., Collins, P.J., Kawaoka, Y., Skehel, J.J., Gamblin, S.J.
登録日2013-03-29
公開日2013-04-24
最終更新日2013-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Receptor Binding by a Ferret-Transmissible H5 Avian Influenza Virus
Nature, 497, 2013
4UO0
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STRUCTURE OF THE A_EQUINE_RICHMOND_07 H3 HAEMAGGLUTININ
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Vachieri, S.G., Collins, P.J., Haire, L.F., Ogrodowicz, R.W., Martin, S.R., Walker, P.A., Xiong, X., Gamblin, S.J., Skehel, J.J.
登録日2014-05-31
公開日2014-07-23
最終更新日2014-08-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Recent Evolution of Equine Influenza and the Origin of Canine Influenza.
Proc.Natl.Acad.Sci.USA, 111, 2014