3PMS
 
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8FIL
 | | Zinc-free APOBEC3A (inactive E72A mutant) in complex with TTC-hairpin DNA substrate | | Descriptor: | CHLORIDE ION, DNA (5'-D(*TP*GP*CP*GP*CP*TP*TP*CP*GP*CP*GP*CP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3A, ... | | Authors: | Harjes, S, Jameson, G.B, Harjes, E, Filichev, V.V, Kurup, H.M. | | Deposit date: | 2022-12-16 | | Release date: | 2023-09-06 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Nat Commun, 14, 2023
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8FIK
 | | APOBEC3A E72A inactive mutant in complex with ATTC-hairpin DNA substrate | | Descriptor: | CHLORIDE ION, DNA (5'-D(P*CP*CP*CP*AP*TP*CP*AP*TP*TP*CP*GP*AP*TP*GP*GP*G)-3'), DNA dC->dU-editing enzyme APOBEC-3A, ... | | Authors: | Harjes, S, Jameson, G.B, Harjes, E, Filichev, V.V, Kurup, H.M. | | Deposit date: | 2022-12-16 | | Release date: | 2023-09-06 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (1.912 Å) | | Cite: | Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Nat Commun, 14, 2023
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8FII
 | | Wild type APOBEC3A in complex with TT(FdZ)-hairpin inhibitor (crystal form 1) | | Descriptor: | DNA (5'-D(P*GP*CP*GP*CP*TP*TP*(UFP)P*GP*CP*GP*C)-3'), DNA dC->dU-editing enzyme APOBEC-3A, PHOSPHATE ION, ... | | Authors: | Harjes, S, Jameson, G.B, Harjes, E, Filichev, V.V, Kurup, H.M. | | Deposit date: | 2022-12-16 | | Release date: | 2023-09-06 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Nat Commun, 14, 2023
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8FIJ
 | | Wild type APOBEC3A in complex with TT(FdZ)-hairpin inhibitor (crystal form 2) | | Descriptor: | DNA (5'-D(*GP*CP*GP*CP*TP*TP*(UFP)P*GP*CP*GP*CP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3A, PHOSPHATE ION, ... | | Authors: | Harjes, S, Jameson, G.B, Harjes, E, Filichev, V.V, Kurup, H.M. | | Deposit date: | 2022-12-16 | | Release date: | 2023-09-06 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (2.799 Å) | | Cite: | Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Nat Commun, 14, 2023
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8FIM
 | | Structure of APOBEC3A (E72A inactive mutant) in complex with TTC-hairpin DNA substrate | | Descriptor: | CHLORIDE ION, DNA (5'-D(*TP*GP*CP*GP*CP*TP*TP*CP*GP*CP*GP*CP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3A, ... | | Authors: | Harjes, S, Jameson, G.B, Harjes, E, Filichev, V.V, Kurup, H.M. | | Deposit date: | 2022-12-16 | | Release date: | 2023-09-06 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Nat Commun, 14, 2023
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