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Glutathione S-transferase bound with hydrolyzed Piperlongumine
Descriptor:	2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-(3,4,5-trimethoxyphenyl)propanoic acid, GLUTATHIONE, ...
Authors:	Harshbarger, W, Gondi, S, Ficarro, S, Hunter, J, Udayakumar, D, Gurbani, D, Marto, J, Westover, K.
Deposit date:	2016-03-31
Release date:	2016-11-30
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.19035351 Å)
Cite:	Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine. J. Biol. Chem., 292, 2017

Crystal structure of PP2A PPP2R1A-PPP2CA-PPP2R5E phosphatase.
Descriptor:	MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:	Wachter, F, Nowak, R.P, Fischer, E.S.
Deposit date:	2023-11-06
Release date:	2024-04-17
Last modified:	2024-05-15
Method:	X-RAY DIFFRACTION (3.15 Å)
Cite:	Structural characterization of methylation-independent PP2A assembly guides alphafold2Multimer prediction of family-wide PP2A complexes. J.Biol.Chem., 300, 2024

Crystal Structure of Focal Adhesion Kinase Domain with 2 molecules in the Asymmetric Unit Complexed with ADP and ATP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Focal Adhesion Kinase 1
Authors:	Lee, C.C.
Deposit date:	2006-09-29
Release date:	2007-08-14
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2.187 Å)
Cite:	Crystal Structure of Focal Adhesion Kinase Catalytic Domain Complexed with ATP and Novel 7H-Pyrrolo [2,3-d] pyrimidine Inhibitor Scaffolds To be Published

Crystal Structure of Focal Adhesion Kinase Domain Complexed with 7H-Pyrrolo [2,3-d] pyrimidine Derivative
Descriptor:	7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE, Focal adhesion kinase 1
Authors:	Lee, C.C.
Deposit date:	2005-10-27
Release date:	2006-10-10
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Crystal Structure of Focal Adhesion Kinase Domain Complexed with ATP and novel 7H-Pyrrolo [2,3-d] pyrimidine scaffolds To be Published