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3ZZJ
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STRUCTURE OF AN ENGINEERED ASPARTATE AMINOTRANSFERASE
Descriptor:ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION, ...
Authors:Fernandez, F.J., deVries, D., Pena-Soler, E., Coll, M., Christen, P., Gehring, H., Vega, M.C.
Deposit date:2011-09-01
Release date:2011-12-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and Mechanism of a Cysteine Sulfinate Desulfinase Engineered on the Aspartate Aminotransferase Scaffold.
Biocim.Biophys.Acta, 1824, 2011
3ZZK
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STRUCTURE OF AN ENGINEERED ASPARTATE AMINOTRANSFERASE
Descriptor:ASPARTATE AMINOTRANSFERASE, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, SULFATE ION, ...
Authors:Fernandez, F.J., deVries, D., Pena-Soler, E., Coll, M., Christen, P., Gehring, H., Vega, M.C.
Deposit date:2011-09-01
Release date:2011-12-28
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure and Mechanism of a Cysteine Sulfinate Desulfinase Engineered on the Aspartate Aminotransferase Scaffold.
Biocim.Biophys.Acta, 1824, 2011
4A00
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STRUCTURE OF AN ENGINEERED ASPARTATE AMINOTRANSFERASE
Descriptor:ASPARTATE AMINOTRANSFERASE, ALANYL-PYRIDOXAL-5'-PHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Fernandez, F.J., deVries, D., Pena-Soler, E., Coll, M., Christen, P., Gehring, H., Vega, M.C.
Deposit date:2011-09-06
Release date:2011-12-28
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structure and Mechanism of a Cysteine Sulfinate Desulfinase Engineered on the Aspartate Aminotransferase Scaffold.
Biocim.Biophys.Acta, 1824, 2011
5FT4
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CRYSTAL STRUCTURE OF THE CYSTEINE DESULFURASE CSDA FROM ESCHERICHIA COLI AT 1.996 ANGSTROEM RESOLUTION
Descriptor:CYSTEINE DESULFURASE CSDA, PYRIDOXAL-5'-PHOSPHATE, GLYCEROL, ...
Authors:Fernandez, F.J., Arda, A., Lopez-Estepa, M., Aranda, J., Penya-Soler, E., Garces, F., Quintana, J.F., Round, A., Campos-Oliva, R., Bruix, M., Coll, M., Tunon, I., Jimenez-Barbero, J., Vega, M.C.
Deposit date:2016-01-11
Release date:2016-12-21
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:The Mechanism of Sulfur Transfer Across Protein- Protein Interfaces: The Csd Model
Acs Catalysis, 6, 2016
5FT5
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CRYSTAL STRUCTURE OF THE CYSTEINE DESULFURASE CSDA (PERSULFURATED) FROM ESCHERICHIA COLI AT 2.384 ANGSTROEM RESOLUTION
Descriptor:L-CYSTEINE DESULFURASE CSDA, GLYCEROL, DI(HYDROXYETHYL)ETHER, ...
Authors:Fernandez, F.J., Arda, A., Lopez-Estepa, M., Aranda, J., Penya-Soler, E., Garces, F., Quintana, J.F., Round, A., Campos-Oliva, R., Bruix, M., Coll, M., Tunon, I., Jimenez-Barbero, J., Vega, M.C.
Deposit date:2016-01-11
Release date:2016-11-23
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.384 Å)
Cite:Mechanism of Sulfur Transfer Across Protein-Protein Interfaces: The Cysteine Desulfurase Model System
Acs Catalysis, 6, 2016
5FT6
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CRYSTAL STRUCTURE OF THE CYSTEINE DESULFURASE CSDA (S-SULFONIC ACID) FROM ESCHERICHIA COLI AT 2.050 ANGSTROEM RESOLUTION
Descriptor:CYSTEINE DESULFURASE CSDA, GLYCEROL, DI(HYDROXYETHYL)ETHER, ...
Authors:Fernandez, F.J., Arda, A., Lopez-Estepa, M., Aranda, J., Penya-Soler, E., Garces, F., Round, A., Campos-Oliva, R., Bruix, M., Coll, M., Tunon, I., Jimenez-Barbero, J., Vega, M.C.
Deposit date:2016-01-11
Release date:2016-11-23
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:Mechanism of Sulfur Transfer Across Protein-Protein Interfaces: The Cysteine Desulfurase Model System
Acs Catalysis, 6, 2016
5FT8
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE CYSTEINE DESULFURASE CSDA AND THE SULFUR-ACCEPTOR CSDE IN THE PERSULFURATED STATE AT 2.50 ANGSTROEM RESOLUTION
Descriptor:CYSTEINE DESULFURASE CSDA, SULFUR ACCEPTOR PROTEIN CSDE, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Fernandez, F.J., Arda, A., Lopez-Estepa, M., Aranda, J., Penya-Soler, E., Garces, F., Round, A., Campos-Oliva, R., Bruix, M., Coll, M., Tunon, I., Jimenez-Barbero, J., Vega, M.C.
Deposit date:2016-01-11
Release date:2016-11-23
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of Sulfur Transfer Across Protein-Protein Interfaces: The Cysteine Desulfurase Model System
Acs Catalysis, 6, 2016
1H1C
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HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (HISC) FROM THERMOTOGA MARITIMA
Descriptor:HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Vega, M.C., Fernandez, F.J., Wilmanns, M.
Deposit date:2002-07-08
Release date:2004-03-19
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase
J.Biol.Chem., 279, 2004
1UU0
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HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (HISC) FROM THERMOTOGA MARITIMA (APO-FORM)
Descriptor:HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PHOSPHATE ION
Authors:Vega, M.C., Fernandez, F.J., Lehmann, F., Wilmanns, M.
Deposit date:2003-12-12
Release date:2004-05-13
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase
J.Biol.Chem., 279, 2004
1UU1
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COMPLEX OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (HISC) FROM THERMOTOGA MARITIMA (APO-FORM)
Descriptor:HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, PHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ESTER
Authors:Vega, M.C., Fernandez, F.J., Lehman, F., Wilmanns, M.
Deposit date:2003-12-12
Release date:2004-03-18
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase
J.Biol.Chem., 279, 2004
1UU2
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HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (HISC) FROM THERMOTOGA MARITIMA (APO-FORM)
Descriptor:HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 1,2-ETHANEDIOL
Authors:Vega, M.C., Fernandez, F.J., Lehmann, F., Wilmanns, M.
Deposit date:2003-12-13
Release date:2004-03-18
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase
J.Biol.Chem., 279, 2004
5O5X
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CRYSTAL STRUCTURE OF THERMOCOCCUS LITORALIS ADP-DEPENDENT GLUCOKINASE (GK)
Descriptor:ADP-dependent glucokinase,ADP-dependent glucokinase,ADP-dependent glucokinase, SULFATE ION, GLYCEROL
Authors:Herrera-Morande, A., Castro-Fernandez, V., Merino, F., Ramirez-Sarmiento, C.A., Fernandez, F.J., Guixe, V., Vega, M.C.
Deposit date:2017-06-02
Release date:2018-10-24
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:Protein topology determines substrate-binding mechanism in homologous enzymes.
Biochim Biophys Acta Gen Subj, 1862, 2018
5O5Y
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CRYSTAL STRUCTURE OF THERMOCOCCUS LITORALIS ADP-DEPENDENT GLUCOKINASE (GK)
Descriptor:ADP-dependent glucokinase,ADP-dependent glucokinase,ADP-dependent glucokinase, GLYCEROL, TRIETHYLENE GLYCOL, ...
Authors:Herrera-Morande, A., Castro-Fernandez, V., Merino, F., Ramirez-Sarmiento, C.A., Fernandez, F.J., Guixe, V., Vega, M.C.
Deposit date:2017-06-02
Release date:2018-10-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.915 Å)
Cite:Protein topology determines substrate-binding mechanism in homologous enzymes.
Biochim Biophys Acta Gen Subj, 1862, 2018
5O5Z
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CRYSTAL STRUCTURE OF THERMOCOCCUS LITORALIS ADP-DEPENDENT GLUCOKINASE (GK)
Descriptor:ADP-dependent glucokinase,ADP-dependent glucokinase,ADP-dependent glucokinase, GLYCEROL, SULFATE ION, ...
Authors:Herrera-Morande, A., Castro-Fernandez, V., Merino, F., Ramirez-Sarmiento, C.A., Fernandez, F.J., Guixe, V., Vega, M.C.
Deposit date:2017-06-02
Release date:2018-10-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.441 Å)
Cite:Protein topology determines substrate-binding mechanism in homologous enzymes.
Biochim Biophys Acta Gen Subj, 1862, 2018
2WYL
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APO STRUCTURE OF A METALLO-B-LACTAMASE
Descriptor:L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG, GLYCEROL, FORMYL GROUP
Authors:Garces, F., Fernandez, F.J., Penya-Soler, E., Aguilar, J., Baldoma, L., Coll, M., Badia, J., Vega, M.C.
Deposit date:2009-11-16
Release date:2010-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Molecular Architecture of the Mn(2+)Dependent Lactonase Ulag Reveals an Rnase-Like Metallo-Beta-Lactamase Fold and a Novel Quaternary Structure.
J.Mol.Biol., 398, 2010
2WYM
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STRUCTURE OF A METALLO-B-LACTAMASE
Descriptor:L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG, MANGANESE (II) ION, GLYCEROL, ...
Authors:Garces, F., Fernandez, F.J., Penya-Soler, E., Aguilar, J., Baldoma, L., Coll, M., Badia, J., Vega, M.C.
Deposit date:2009-11-16
Release date:2010-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Architecture of the Mn(2+)Dependent Lactonase Ulag Reveals an Rnase-Like Metallo-Beta-Lactamase Fold and a Novel Quaternary Structure.
J.Mol.Biol., 398, 2010
5NQ6
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CRYSTAL STRUCTURE OF THE INHIBITED FORM OF THE REDOX-SENSITIVE SUFE-LIKE SULFUR ACCEPTOR CSDE FROM ESCHERICHIA COLI AT 2.40 ANGSTROM RESOLUTION
Descriptor:Sulfur acceptor protein CsdE, GLYCEROL, SULFATE ION
Authors:Penya-Soler, E., Aranda, J., Lopez-Estepa, M., Gomez, S., Garces, F., Coll, M., Fernandez, F.J., Vega, M.C.
Deposit date:2017-04-19
Release date:2018-03-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Insights into the inhibited form of the redox-sensitive SufE-like sulfur acceptor CsdE.
PLoS ONE, 12, 2017
6FZH
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CRYSTAL STRUCTURE OF A STREPTOCOCCAL DEHYDROGENASE AT 1.5 ANGSTROEM RESOLUTION
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ...
Authors:Gomez, S., Querol-Garcia, J., Sanchez-Barron, G., Subias, M., Gonzalez-Alsina, A., Melchor-Tafur, C., Franco-Hidalgo, V., Alberti, S., Rodriguez de Cordoba, S., Fernandez, F.J., Vega, M.C.
Deposit date:2018-03-14
Release date:2019-03-27
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Antimicrobials Anacardic Acid and Curcumin Are Not-Competitive Inhibitors of Gram-Positive Bacterial Pathogenic Glyceraldehyde-3-Phosphate Dehydrogenase by a Mechanism Unrelated to Human C5a Anaphylatoxin Binding.
Front Microbiol, 10, 2019
6FZI
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CRYSTAL STRUCTURE OF A CLOSTRIDIAL DEHYDROGENASE AT 2.55 ANGSTROEMS RESOLUTION
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ...
Authors:Gomez, S., Querol-Garcia, J., Sanchez-Barron, G., Subias, M., Gonzalez-Alsina, A., Melchor-Tafur, C., Franco-Hidalgo, V., Alberti, S., Rodriguez de Cordoba, S., Fernandez, F.J., Vega, M.C.
Deposit date:2018-03-14
Release date:2019-03-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The Antimicrobials Anacardic Acid and Curcumin Are Not-Competitive Inhibitors of Gram-Positive Bacterial Pathogenic Glyceraldehyde-3-Phosphate Dehydrogenase by a Mechanism Unrelated to Human C5a Anaphylatoxin Binding.
Front Microbiol, 10, 2019
6RJN
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CRYSTAL STRUCTURE OF A FUNGAL CATALASE AT 2.3 ANGSTROMS
Descriptor:Catalase, PROTOPORPHYRIN IX CONTAINING FE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Gomez, S., Navas-Yuste, S., Payne, A.M., Rivera, W., Lopez-Estepa, M., Brangbour, C., Fulla, D., Juanhuix, J., Fernandez, F.J., Vega, M.C.
Deposit date:2019-04-28
Release date:2020-03-04
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Peroxisomal catalases from the yeasts Pichia pastoris and Kluyveromyces lactis as models for oxidative damage in higher eukaryotes.
Free Radic. Biol. Med., 141, 2019
4B8R
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CRYSTAL STRUCTURE OF THERMOCOCCUS LITORALIS ADP-DEPENDENT GLUCOKINASE (GK)
Descriptor:ADP-DEPENDENT GLUCOKINASE, GLYCEROL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Herrera-Morande, A., Rivas-Pardo, J.A., Fernandez, F.J., Guixe, V., Vega, M.C.
Deposit date:2012-08-30
Release date:2013-07-10
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure, Saxs and Kinetic Mechanism of Hyperthermophilic Adp-Dependent Glucokinase from Thermococcus Litoralis Reveal a Conserved Mechanism for Catalysis.
Plos One, 8, 2013
4B8S
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CRYSTAL STRUCTURE OF THERMOCOCCUS LITORALIS ADP-DEPENDENT GLUCOKINASE (GK)
Descriptor:ADP-DEPENDENT GLUCOKINASE, alpha-D-glucopyranose, GLYCEROL, ...
Authors:Herrera-Morande, A., Rivas-Pardo, J.A., Fernandez, F.J., Guixe, V., Vega, M.C.
Deposit date:2012-08-30
Release date:2013-07-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Crystal Structure, Saxs and Kinetic Mechanism of Hyperthermophilic Adp-Dependent Glucokinase from Thermococcus Litoralis Reveal a Conserved Mechanism for Catalysis.
Plos One, 8, 2013
1USY
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ATP PHOSPHORIBOSYL TRANSFERASE (HISG:HISZ) COMPLEX FROM THERMOTOGA MARITIMA
Descriptor:ATP PHOSPHORIBOSYLTRANSFERASE REGULATORY SUBUNIT, ATP PHOSPHORIBOSYLTRANSFERASE, HISTIDINE, ...
Authors:Vega, M.C., Fernandez, F.J., Murphy, G.E., Zou, P., Popov, A., Wilmanns, M.
Deposit date:2003-12-01
Release date:2004-12-15
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Regulation of the Hetero-Octameric ATP Phosphoribosyl Transferase Complex from Thermotoga Maritima by a tRNA Synthetase-Like Subunit.
Mol.Microbiol., 55, 2005
4CVQ
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CRYSTAL STRUCTURE OF AN AMINOTRANSFERASE FROM ESCHERICHIA COLI AT 2. 11 ANGSTROEM RESOLUTION
Descriptor:GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA, PYRIDOXAL-5'-PHOSPHATE, ACETATE ION, ...
Authors:Penya-Soler, E., Fernandez, F.J., Lopez-Estepa, M., Garces, F., Richardson, A.J., Rudd, K.E., Coll, M., Vega, M.C.
Deposit date:2014-03-28
Release date:2014-07-23
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structural analysis and mutant growth properties reveal distinctive enzymatic and cellular roles for the three major L-alanine transaminases of Escherichia coli.
PLoS ONE, 9, 2014
4D79
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CRYSTAL STRUCTURE OF E. COLI TRNA N6-THREONYLCARBAMOYLADENOSINE DEHYDRATASE, TCDA, IN COMPLEX WITH ATP AT 1.768 ANGSTROEM RESOLUTION
Descriptor:TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE, POTASSIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Lopez-Estepa, M., Arda, A., Savko, M., Round, A., Shepard, W., Bruix, M., Coll, M., Fernandez, F.J., Jimenez-Barbero, J., Vega, M.C.
Deposit date:2014-11-21
Release date:2015-05-06
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.768 Å)
Cite:The Crystal Structure and Small-Angle X-Ray Analysis of Csdl/Tcda Reveal a New tRNA Binding Motif in the Moeb/E1 Superfamily.
Plos One, 10, 2015
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171588
PDB entries from 2020-11-25