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1AGK
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THE SOLUTION NMR STRUCTURE OF AN (R)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE SECOND POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*CP*GP*GP*AP*CP*RP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3')
Authors:Feng, B., Stone, M.P.
Deposit date:1997-03-25
Release date:1997-08-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Major groove (R)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the R(61,2) and R(61,3) sequence isomers from 1H NMR.
Biochemistry, 34, 1995
1AGO
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THE SOLUTION NMR STRUCTURE OF AN (S)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE THIRD POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*CP*GP*GP*AP*CP*AP*YP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3')
Authors:Feng, B., Stone, M.P.
Deposit date:1997-03-25
Release date:1997-08-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Major groove (S)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the S(61,2) and S(61,3) sequence isomers from 1H NMR.
Biochemistry, 35, 1996
1AGZ
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THE SOLUTION NMR STRUCTURE OF AN (R)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE THIRD POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*CP*GP*GP*AP*CP*AP*RP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3')
Authors:Feng, B., Stone, M.P.
Deposit date:1997-03-26
Release date:1997-08-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Major groove (R)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the R(61,2) and R(61,3) sequence isomers from 1H NMR.
Biochemistry, 34, 1995
1AGH
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THE SOLUTION STRUCTURE OF AN 11 BASE-PAIR OLIGONUCLEOTIDE DUPLEX CODING FOR AMINO ACIDS 60-62 OF THE PRODUCT OF THE N-RAS PROTOONCOGENE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*CP*GP*GP*AP*CP*AP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3')
Authors:Feng, B., Stone, M.P.
Deposit date:1997-03-25
Release date:1997-09-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of an oligodeoxynucleotide containing the human n-ras codon 61 sequence refined from 1H NMR using molecular dynamics restrained by nuclear Overhauser effects.
Chem.Res.Toxicol., 8, 1995
1AXL
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SOLUTION CONFORMATION OF THE (-)-TRANS-ANTI-[BP]DG ADDUCT OPPOSITE A DELETION SITE IN DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG), NMR, 6 STRUCTURES
Descriptor:DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG), 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE
Authors:Feng, B., Gorin, A.A., Kolbanovskiy, A., Hingerty, B.E., Geacintov, N.E., Broyde, S., Patel, D.J.
Deposit date:1997-10-16
Release date:1998-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
Biochemistry, 36, 1997
1AXO
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STRUCTURAL ALIGNMENT OF THE (+)-TRANS-ANTI-[BP]DG ADDUCT POSITIONED OPPOSITE DC AT A DNA TEMPLATE-PRIMER JUNCTION, NMR, 6 STRUCTURES
Descriptor:DNA DUPLEX D(AAC-[BP]G-CTACCATCC)D(GGATGGTAGC), 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE
Authors:Feng, B., Gorin, A.A., Hingerty, B.E., Geacintov, N.E., Broyde, S., Patel, D.J.
Deposit date:1997-10-16
Release date:1998-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction.
Biochemistry, 36, 1997
4CSU
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CRYO-EM STRUCTURES OF THE 50S RIBOSOME SUBUNIT BOUND WITH OBGE
Descriptor:50S RIBOSOMAL PROTEIN L28, 50S RIBOSOMAL PROTEIN L29, 50S RIBOSOMAL PROTEIN L30, ...
Authors:Feng, B., Mandava, C.S., Guo, Q., Wang, J., Cao, W., Li, N., Zhang, Y., Zhang, Y., Wang, Z., Wu, J., Sanyal, S., Lei, J., Gao, N.
Deposit date:2014-03-10
Release date:2014-06-04
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
Plos Biol., 12, 2014
2YKR
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30S RIBOSOMAL SUBUNIT WITH RSGA BOUND IN THE PRESENCE OF GMPPNP
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Guo, Q., Yuan, Y., Xu, Y., Feng, B., Liu, L., Chen, K., Lei, J., Gao, N.
Deposit date:2011-05-30
Release date:2011-08-24
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structural Basis for the Function of a Small Gtpase Rsga on the 30S Ribosomal Subunit Maturation Revealed by Cryoelectron Microscopy.
Proc.Natl.Acad.Sci.USA, 108, 2011
3J8G
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF ENGA BOUND WITH THE 50S RIBOSOMAL SUBUNIT
Descriptor:5S rRNA, 23S rRNA, 50S ribosomal protein L28, ...
Authors:Zhang, X., Yan, K., Zhang, Y., Li, N., Ma, C., Li, Z., Zhang, Y., Feng, B., Liu, J., Sun, Y., Xu, Y., Lei, J., Gao, N.
Deposit date:2014-10-24
Release date:2014-11-26
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
3TV4
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HUMAN B-RAF KINASE DOMAIN IN COMPLEX WITH AN BROMOPYRIDINE BENZAMIDE INHIBITOR
Descriptor:Serine/threonine-protein kinase B-raf, N-(6-amino-5-bromopyridin-3-yl)-2,6-difluoro-3-[(propylsulfonyl)amino]benzamide
Authors:Voegtli, W.C., Selby, L.T., Wu, W.-I.
Deposit date:2011-09-19
Release date:2011-10-05
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors.
ACS Med Chem Lett, 2, 2011
3TV6
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HUMAN B-RAF KINASE DOMAIN IN COMPLEX WITH A METHOXYPYRAZOLOPYRIDINYL BENZAMIDE INHIBITOR
Descriptor:Serine/threonine-protein kinase B-raf, 2,6-difluoro-N-(3-methoxy-2H-pyrazolo[3,4-b]pyridin-5-yl)-3-[(propylsulfonyl)amino]benzamide
Authors:Voegtli, W.C., Sturgis, H.L., Wu, W.-I.
Deposit date:2011-09-19
Release date:2011-10-05
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors.
ACS Med Chem Lett, 2, 2011
3UW4
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CRYSTAL STRUCTURE OF CIAP1 BIR3 BOUND TO GDC0152
Descriptor:Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 4, GDC0152, ...
Authors:Maurer, B., Hymowitz, S.
Deposit date:2011-11-30
Release date:2012-02-22
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152).
J.Med.Chem., 55, 2012
3UW5
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CRYSTAL STRUCTURE OF THE BIR DOMAIN OF MLIAP BOUND TO GDC0152
Descriptor:Baculoviral IAP repeat-containing protein 7, Baculoviral IAP repeat-containing protein 4, GDC-0152, ...
Authors:Maurer, B., Hymowitz, S.G.
Deposit date:2011-11-30
Release date:2012-02-22
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152).
J.Med.Chem., 55, 2012
3SKC
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HUMAN B-RAF KINASE IN COMPLEX WITH AN AMIDE LINKED PYRAZOLOPYRIDINE INHIBITOR
Descriptor:Serine/threonine-protein kinase B-raf, 2,6-difluoro-N-[(5S)-3-methoxy-5H-pyrazolo[3,4-b]pyridin-5-yl]-3-[(phenylsulfonyl)amino]benzamide
Authors:Voegtli, W.C., Sturgis, H.L.
Deposit date:2011-06-22
Release date:2011-08-17
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Pyrazolopyridine inhibitors of B-RafV600E. Part 2: structure-activity relationships.
Bioorg.Med.Chem.Lett., 21, 2011
2PU2
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AMPC BETA-LACTAMASE WITH BOUND PHTHALAMIDE INHIBITOR
Descriptor:Beta-lactamase, PHOSPHATE ION, 2-[(1R)-1-CARBOXY-2-(4-HYDROXYPHENYL)ETHYL]-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID
Authors:Babaoglu, K., Shoichet, B.K.
Deposit date:2007-05-08
Release date:2008-04-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase.
J.Med.Chem., 51, 2008
2PU4
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AMPC BETA-LACAMASE WITH BOUND COVALENT OXADIAZOLE INHIBITOR
Descriptor:Beta-lactamase, DIMETHYL SULFOXIDE, TERT-BUTYL [(1R)-2-METHYL-1-(1,3,4-OXADIAZOL-2-YL)PROPYL]CARBAMATE, ...
Authors:Babaoglu, K., Shoichet, B.K.
Deposit date:2007-05-08
Release date:2008-04-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase.
J.Med.Chem., 51, 2008
2R9W
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AMPC BETA-LACTAMASE WITH BOUND PHTHALAMIDE INHIBITOR
Descriptor:Beta-lactamase, PHOSPHATE ION, 2-[(1R)-1-carboxy-2-naphthalen-1-ylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid
Authors:Babaoglu, K., Shoichet, B.K.
Deposit date:2007-09-13
Release date:2008-04-15
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase.
J.Med.Chem., 51, 2008
2R9X
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AMPC BETA-LACTAMASE WITH BOUND PHTHALAMIDE INHIBITOR
Descriptor:Beta-lactamase, PHOSPHATE ION, 2-[(1R)-2-carboxy-1-(naphthalen-1-ylmethyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid, ...
Authors:Babaoglu, K., Shoichet, B.K.
Deposit date:2007-09-13
Release date:2008-04-15
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase.
J.Med.Chem., 51, 2008
3J28
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-13
Method:ELECTRON MICROSCOPY (12.9 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J29
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-13
Method:ELECTRON MICROSCOPY (14 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J2A
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2014-10-22
Method:ELECTRON MICROSCOPY (13.1 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J2B
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-13
Method:ELECTRON MICROSCOPY (13.6 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J2C
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA head domain, 16S rRNA body domain
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-13
Method:ELECTRON MICROSCOPY (13.2 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J2D
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-06
Method:ELECTRON MICROSCOPY (18.700001 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J2E
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-06
Method:ELECTRON MICROSCOPY (15.3 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
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