Author results

6D0T
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DE NOVO DESIGN OF A FLUORESCENCE-ACTIVATING BETA BARREL - BB1
Descriptor:BB1
Authors:Dou, J., Vorobieva, A.A., Sheffler, W., Doyle, L.A., Park, H., Bick, M.J., Mao, B., Foight, G.W., Lee, M., Carter, L., Sankaran, B., Ovchinnikov, S., Marcos, E., Huang, P., Vaughan, J.C., Stoddard, B.L., Baker, D.
Deposit date:2018-04-10
Release date:2018-09-19
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
5IER
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STRUCTURE OF A COMPUTATIONALLY DESIGNED 17-OHP BINDER
Descriptor:OHP9, (9beta)-17-hydroxypregn-4-ene-3,20-dione, SULFATE ION, ...
Authors:Stoddard, B.L., Doyle, L.A.
Deposit date:2016-02-25
Release date:2017-03-01
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Sampling and energy evaluation challenges in ligand binding protein design.
Protein Sci., 26, 2017
5IF6
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STRUCTURE OF A COMPUTATIONALLY DESIGNED 17-OHP BINDER
Descriptor:OHP9_1c, (9beta)-17-hydroxypregn-4-ene-3,20-dione, SODIUM ION
Authors:Stoddard, B.L., Doyle, L.A.
Deposit date:2016-02-25
Release date:2017-03-01
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Sampling and energy evaluation challenges in ligand binding protein design.
Protein Sci., 26, 2017
6CZG
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STRUCTURE OF A REDESIGNED BETA BARREL, B11L5F_LGL
Descriptor:b11L5F_LGL
Authors:Doyle, L.A., Stoddard, B.L.
Deposit date:2018-04-09
Release date:2018-09-19
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
6CZH
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STRUCTURE OF A REDESIGNED BETA BARREL, MFAP0, BOUND TO DFHBI
Descriptor:mFAP0, (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one
Authors:Doyle, L.A., Stoddard, B.L.
Deposit date:2018-04-09
Release date:2018-09-19
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
6CZI
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STRUCTURE OF A REDESIGNED BETA BARREL, MFAP1, BOUND TO DFHBI
Descriptor:mFAP1, (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one
Authors:Doyle, L.A., Stoddard, B.L.
Deposit date:2018-04-09
Release date:2018-09-19
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
6CZJ
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STRUCTURE OF A REDESIGNED BETA BARREL, B10
Descriptor:b10, SULFATE ION
Authors:Doyle, L.A., Stoddard, B.L.
Deposit date:2018-04-09
Release date:2018-09-19
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
4J8T
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ENGINEERED DIGOXIGENIN BINDER DIG10.2
Descriptor:Engineered Digoxigenin binder protein DIG10.2, DIGOXIGENIN
Authors:Stoddard, B.L., Doyle, L.A.
Deposit date:2013-02-14
Release date:2013-06-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Computational design of ligand-binding proteins with high affinity and selectivity.
Nature, 501, 2013
4J9A
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ENGINEERED DIGOXIGENIN BINDER DIG10.3
Descriptor:Engineered Digoxigenin binder protein DIG10.3, DIGOXIGENIN
Authors:Stoddard, B.L., Doyle, L.A.
Deposit date:2013-02-15
Release date:2013-06-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Computational design of ligand-binding proteins with high affinity and selectivity.
Nature, 501, 2013
5BVB
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ENGINEERED DIGOXIGENIN BINDER DIG5.1A
Descriptor:DIG5.1a, DIGOXIGENIN
Authors:Doyle, L.A., Stoddard, B.L.
Deposit date:2015-06-04
Release date:2015-10-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:CSAR Benchmark Exercise 2013: Evaluation of Results from a Combined Computational Protein Design, Docking, and Scoring/Ranking Challenge.
J.Chem.Inf.Model., 56, 2016
5KPE
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SOLUTION NMR STRUCTURE OF DENOVO BETA SHEET DESIGN PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR664
Descriptor:De novo Beta Sheet Design Protein OR664
Authors:Tang, Y., Liu, G., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2016-07-03
Release date:2016-09-21
Last modified:2017-11-01
Method:SOLUTION NMR
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5KPH
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SOLUTION NMR STRUCTURE OF DENOVO BETA SHEET DESIGN PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR485
Descriptor:De novo Beta Sheet Design Protein OR485
Authors:Tang, Y., Liu, G., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2016-07-04
Release date:2016-09-28
Last modified:2017-11-01
Method:SOLUTION NMR
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5L33
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
Descriptor:denovo NTF2
Authors:Oberdorfer, G., Marcos, E., Basanta, B., Chidyausiku, T.M., Sankaran, B., Baker, D.
Deposit date:2016-08-03
Release date:2017-01-25
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TPH
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN HOMODIMER WITH CURVED BETA-SHEET
Descriptor:de novo NTF2 homodimer, DI(HYDROXYETHYL)ETHER, CHLORIDE ION
Authors:Basanta, B., Marcos, E., Oberdorfer, G., Chidyausiku, T.M., Sankaran, B., Baker, D.
Deposit date:2016-10-20
Release date:2017-01-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TPJ
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
Descriptor:denovo NTF2
Authors:Basanta, B., Oberdorfer, G., Marcos, E., Chidyausiku, T.M., Sankaran, B., Baker, D.
Deposit date:2016-10-20
Release date:2017-01-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TRV
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
Descriptor:denovo NTF2, DI(HYDROXYETHYL)ETHER
Authors:Basanta, B., Oberdorfer, G., Marcos, E., Chidyausiku, T.M., Sankaran, B., Baker, D.
Deposit date:2016-10-27
Release date:2017-01-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TS4
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
Descriptor:denovo NTF2, DI(HYDROXYETHYL)ETHER
Authors:Basanta, B., Oberdorfer, G., Chidyausiku, T.M., Marcos, E., Pereira, J.H., Sankaran, B., Zwart, P.H., Baker, D.
Deposit date:2016-10-27
Release date:2017-01-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5U35
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
Descriptor:De novo NTF2 with large cavity, 2-METHOXYETHANOL, CHLORIDE ION, ...
Authors:Oberdorfer, G., Marcos, E., Basanta, B., Chidyausiku, T.M., Sankaran, B., Zwart, P.H., Baker, D.
Deposit date:2016-12-01
Release date:2017-01-25
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017