Author results

1S29
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LA AUTOANTIGEN N-TERMINAL DOMAIN
Descriptor:La protein
Authors:Dong, G., Chakshusmathi, G., Wolin, S.L., Reinisch, K.M.
Deposit date:2004-01-08
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the La motif: a winged helix domain mediates RNA binding via a conserved aromatic patch.
Embo J., 23, 2004
1K8H
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NMR STRUCTURE OF SMALL PROTEIN B (SMPB) FROM AQUIFEX AEOLICUS
Descriptor:Small protein B
Authors:Dong, G., Hoffman, D.W.
Deposit date:2001-10-24
Release date:2002-03-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of small protein B: the protein component of the tmRNA-SmpB system for ribosome rescue.
EMBO J., 21, 2002
2B1E
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THE STRUCTURES OF EXOCYST SUBUNIT EXO70P AND THE EXO84P C-TERMINAL DOMAINS REVEAL A COMMON MOTIF
Descriptor:Exocyst complex component EXO70
Authors:Dong, G., Hutagalung, A.H., Fu, C., Novick, P., Reinisch, K.M.
Deposit date:2005-09-15
Release date:2005-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif
Nat.Struct.Mol.Biol., 12, 2005
2D2S
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CRYSTAL STRUCTURE OF THE EXO84P C-TERMINAL DOMAINS
Descriptor:Exocyst complex component EXO84
Authors:Dong, G., Hutagalung, A.H., Fu, C., Novick, P., Reinisch, K.M.
Deposit date:2005-09-16
Release date:2005-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif
Nat.Struct.Mol.Biol., 12, 2005
3F8U
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TAPASIN/ERP57 HETERODIMER
Descriptor:Protein disulfide-isomerase A3ERp57, Tapasin, N-ACETYL-D-GLUCOSAMINE
Authors:Dong, G., Reinisch, K.M.
Deposit date:2008-11-13
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer.
Immunity, 30, 2009
2OCY
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COMPLEX OF THE GUANINE EXCHANGE FACTOR SEC2P AND THE RAB GTPASE SEC4P
Descriptor:Rab guanine nucleotide exchange factor SEC2, Ras-related protein SEC4
Authors:Reinisch, K.M., Dong, G.
Deposit date:2006-12-21
Release date:2007-02-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A Catalytic Coiled Coil: Structural Insights into the Activation of the Rab GTPase Sec4p by Sec2p.
Mol.Cell, 25, 2007
4NK7
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CRYSTAL STRUCTURE OF THE D. MELANOGASTER PLK4 CRYPTIC POLO BOX (CPB)
Descriptor:Serine/threonine-protein kinase PLK4
Authors:Dong, G., Lesigang, J.
Deposit date:2013-11-12
Release date:2014-08-27
Method:X-RAY DIFFRACTION (3.233 Å)
Cite:Structure of the C. elegans ZYG-1 Cryptic Polo Box Suggests a Conserved Mechanism for Centriolar Docking of Plk4 Kinases.
Structure, 22, 2014
2MEK
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N-TERMINAL DOMAIN OF BILBO1 FROM TRYPANOSOMA BRUCEI
Descriptor:N-TERMINAL DOMAIN OF BILBO1
Authors:Vidilaseris, K., Morriswood, B., Kontaxis, G., Dong, G.
Deposit date:2013-09-24
Release date:2014-01-01
Method:SOLUTION NMR
Cite:Structure and assembly mechanism of TbBILBO1, an essential flagellar pocket collar protein
To be Published
4GKW
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CRYSTAL STRUCTURE OF THE COILED-COIL DOMAIN OF C. ELEGANS SAS-6
Descriptor:Spindle assembly abnormal protein 6
Authors:Qiao, R., Dong, G.
Deposit date:2012-08-13
Release date:2012-11-21
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:SAS-6 coiled-coil structure and interaction with SAS-5 suggest a regulatory mechanism in C. elegans centriole assembly.
Embo J., 31, 2012
3K53
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CRYSTAL STRUCTURE OF NFEOB FROM P. FURIOSUS
Descriptor:Ferrous iron transport protein b
Authors:Eng, E.T., Dong, G., Unger, V.M.
Deposit date:2009-10-06
Release date:2010-05-26
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural fold, conservation and Fe(II) binding of the intracellular domain of prokaryote FeoB.
J.Struct.Biol., 170, 2010
4NKB
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CRYSTAL STRUCTURE OF THE CRYPTIC POLO BOX (CPB)OF ZYG-1
Descriptor:Probable serine/threonine-protein kinase zyg-1, MAGNESIUM ION, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ...
Authors:Shimanovskaya, E., Dong, G.
Deposit date:2013-11-12
Release date:2014-08-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the C. elegans ZYG-1 Cryptic Polo Box Suggests a Conserved Mechanism for Centriolar Docking of Plk4 Kinases.
Structure, 22, 2014
5LG4
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CRYSTAL STRUCTURE OF THE SEC3/SSO2 COMPLEX AT 2.9 ANGSTROM RESOLUTION
Descriptor:Protein SSO2, Exocyst complex component SEC3, SULFATE ION
Authors:Zhang, Y.B., Dong, G.
Deposit date:2016-07-05
Release date:2017-02-08
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion.
Nat Commun, 8, 2017
5M4Y
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CRYSTAL STRUCTURE OF THE SEC3/SSO2 COMPLEX AT 2.20 ANGSTROM RESOLUTION
Descriptor:Protein SSO2, Exocyst complex component SEC3, GLYCEROL
Authors:Zhang, Y.B., Dong, G.
Deposit date:2016-10-19
Release date:2017-02-08
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion.
Nat Commun, 8, 2017
6FND
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII AKMT
Descriptor:Apical complex lysine methyltransferase, ZINC ION, SULFATE ION, ...
Authors:Pivovarova, Y., Dong, G.
Deposit date:2018-02-02
Release date:2018-11-14
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structure of a Novel Dimeric SET Domain Methyltransferase that Regulates Cell Motility.
J. Mol. Biol., 430, 2018
5UBB
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CRYSTAL STRUCTURE OF HUMAN ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1B
Descriptor:Alpha N-terminal protein methyltransferase 1B, S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION
Authors:Dong, C., Zhu, L., Tempel, W., Dong, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2016-12-20
Release date:2017-03-22
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2.
Commun Biol, 1, 2018
6DUB
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CRYSTAL STRUCTURE OF A METHYLTRANSFERASE
Descriptor:Alpha N-terminal protein methyltransferase 1B, RCC1, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Dong, C., Tempel, W., Li, Y., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2018-06-20
Release date:2018-07-25
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2.
Commun Biol, 1, 2018
2WIA
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CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN APO FORM
Descriptor:FERROUS IRON TRANSPORT PROTEIN B, MAGNESIUM ION
Authors:Hung, K.-W., Chang, Y.-W., Chen, J.-H., Chen, Y.-C., Sun, Y.-J., Hsiao, C.-D., Huang, T.-H.
Deposit date:2009-05-09
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Fold, Conservation and Fe(II) Binding of the Intracellular Domain of Prokaryote Feob.
J.Struct.Biol., 170, 2010
2WIB
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CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN GDP BINDING STATE
Descriptor:FERROUS IRON TRANSPORT PROTEIN B, GUANOSINE-5'-DIPHOSPHATE
Authors:Hung, K.-W., Chang, Y.-W., Chen, J.-H., Chen, Y.-C., Sun, Y.-J., Hsiao, C.-D., Huang, T.-H.
Deposit date:2009-05-09
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural Fold, Conservation and Fe(II) Binding of the Intracellular Domain of Prokaryote Feob.
J.Struct.Biol., 170, 2010
2WIC
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CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN GMPPNP BINDING STATE
Descriptor:FERROUS IRON TRANSPORT PROTEIN B, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION
Authors:Hung, K.-W., Chang, Y.-W., Chen, J.-H., Chen, Y.-C., Sun, Y.-J., Hsiao, C.-D., Huang, T.-H.
Deposit date:2009-05-09
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Fold, Conservation and Fe(II) Binding of the Intracellular Domain of Prokaryote Feob.
J.Struct.Biol., 170, 2010
5X72
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THE CRYSTAL STRUCTURE PDE DELTA IN COMPLEX WITH (RAC)-P9
Descriptor:Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, (2R)-2-(2-fluorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one, (2S)-2-(2-fluorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one
Authors:Jiang, Y., Zhuang, C., Chen, L., Wang, R., Wang, F., Sheng, C.
Deposit date:2017-02-23
Release date:2017-10-04
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors
J. Med. Chem., 60, 2017
5X73
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THE CRYSTAL STRUCTURE PDE DELTA IN COMPLEX WITH R-P9
Descriptor:Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, (2R)-2-(2-fluorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one
Authors:Jiang, Y., Zhuang, C., Chen, L., Wang, R., Wang, F., Sheng, C.
Deposit date:2017-02-23
Release date:2017-10-04
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors
J. Med. Chem., 60, 2017
5X74
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THE CRYSTAL STRUCTURE PDE DELTA IN COMPLEX WITH COMPOUND (R, R)-1G
Descriptor:Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, (2R)-2-(2-fluorophenyl)-3-[2-[4-[(2R)-2-(2-fluorophenyl)-4-oxidanylidene-1,2-dihydroquinazolin-3-yl]piperidin-1-yl]ethyl]-1,2-dihydroquinazolin-4-one
Authors:Jiang, Y., Zhuang, C., Chen, L., Wang, R., Wang, F., Sheng, C.
Deposit date:2017-02-23
Release date:2017-10-04
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors
J. Med. Chem., 60, 2017
6DTN
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THE STRUCTURE OF NTMT1 IN COMPLEX WITH COMPOUND DC100-1
Descriptor:N-terminal Xaa-Pro-Lys N-methyltransferase 1, (6D6)PPKRIA(NH2), DC100-1
Authors:Noinaj, N., Chen, D., Huang, R.
Deposit date:2018-06-18
Release date:2019-04-03
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.475 Å)
Cite:Discovery of Bisubstrate Inhibitors for Protein N-Terminal Methyltransferase 1.
J. Med. Chem., 62, 2019
1ZC8
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COORDINATES OF TMRNA, SMPB, EF-TU AND H44 FITTED INTO CRYO-EM MAP OF THE 70S RIBOSOME AND TMRNA COMPLEX
Descriptor:TLD 16S ribosomal RNA, H2 16S rRNA, H2b d mRNA, ...
Authors:Valle, M., Gillet, R., Kaur, S., Henne, A., Ramakrishnan, V., Frank, J.
Deposit date:2005-04-11
Release date:2005-04-19
Last modified:2013-12-11
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Visualizing tmRNA Entry into a Stalled Ribosome
Science, 300, 2003