Author results

1CKM
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STRUCTURE OF TWO DIFFERENT CONFORMATIONS OF MRNA CAPPING ENZYME IN COMPLEX WITH GTP
Descriptor:MRNA CAPPING ENZYME, GUANOSINE-5'-TRIPHOSPHATE
Authors:Hakansson, K., Doherty, A.J., Wigley, D.B.
Deposit date:1997-04-20
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes.
Cell(Cambridge,Mass.), 89, 1997
1CKN
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STRUCTURE OF GUANYLYLATED MRNA CAPPING ENZYME COMPLEXED WITH GTP
Descriptor:MRNA CAPPING ENZYME, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Hakansson, K., Doherty, A.J., Wigley, D.B.
Deposit date:1997-04-20
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes.
Cell(Cambridge,Mass.), 89, 1997
1GZH
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CRYSTAL STRUCTURE OF THE BRCT DOMAINS OF HUMAN 53BP1 BOUND TO THE P53 TUMOR SUPRESSOR
Descriptor:CELLULAR TUMOR ANTIGEN P53, TUMOR SUPPRESSOR P53-BINDING PROTEIN 1, ZINC ION, ...
Authors:Derbyshire, D.J., Doherty, A.J.
Deposit date:2002-05-22
Release date:2002-06-27
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Human 53BP1 Brct Domains Bound to P53 Tumour Suppressor
Embo J., 21, 2002
2R9L
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POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH DNA
Descriptor:DNA (5'-D(P*DGP*DCP*DGP*DGP*DC)-3'), DNA (5'-D(*DGP*DCP*DCP*DGP*DCP*DAP*DAP*DCP*DGP*DCP*DA)-3'), DNA (5'-D(*DGP*DCP*DCP*DGP*DCP*DAP*DAP*DCP*DGP*DCP*DAP*DCP*DG)-3'), ...
Authors:Brissett, N.C., Fox, G.C., Pitcher, R.S., Doherty, A.J.
Deposit date:2007-09-13
Release date:2008-01-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a NHEJ polymerase-mediated DNA synaptic complex
Science, 318, 2007
2IRU
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CRYSTAL STRUCTURE OF THE POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D
Descriptor:Putative DNA ligase-like protein Rv0938/MT0965
Authors:Brissett, N.C., Pitcher, R.S., Doherty, A.J.
Deposit date:2006-10-16
Release date:2007-01-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and function of a mycobacterial NHEJ DNA repair polymerase.
J.Mol.Biol., 366, 2007
2IRX
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CRYSTAL STRUCTURE OF THE POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D WITH GTP AND MANGANESE.
Descriptor:DNA ligase-like protein Rv0938/MT0965, MANGANESE (II) ION, GUANOSINE-5'-TRIPHOSPHATE
Authors:Brissett, N.C., Pitcher, R.S., Doherty, A.J.
Deposit date:2006-10-16
Release date:2007-01-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and function of a mycobacterial NHEJ DNA repair polymerase.
J.Mol.Biol., 366, 2007
2IRY
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CRYSTAL STRUCTURE OF THE POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D WITH DGTP AND MANGANESE.
Descriptor:DNA ligase-like protein Rv0938/MT0965, MANGANESE (II) ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
Authors:Brissett, N.C., Pitcher, R.S., Doherty, A.J.
Deposit date:2006-10-16
Release date:2007-01-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure and function of a mycobacterial NHEJ DNA repair polymerase.
J.Mol.Biol., 366, 2007
3PKY
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POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH DNA, UTP AND MANGANESE.
Descriptor:Putative DNA ligase-like protein, DNA 5'-D(P*GP*CP*GP*GP*C)-3', DNA 5'-D(*G*CP*CP*GP*CP*AP*AP*CP*GP*CP*AP*CP*G)-3', ...
Authors:Brissett, N.C., Fox, G.C., Pitcher, R.S., Doherty, A.J.
Deposit date:2010-11-12
Release date:2011-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a Preternary Complex Involving a Prokaryotic NHEJ DNA Polymerase.
Mol.Cell, 41, 2011
1A0I
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ATP-DEPENDENT DNA LIGASE FROM BACTERIOPHAGE T7 COMPLEX WITH ATP
Descriptor:DNA LIGASE, ADENOSINE-5'-TRIPHOSPHATE
Authors:Subramanya, H.S., Doherty, A.J., Ashford, S.R., Wigley, D.B.
Deposit date:1997-12-01
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of an ATP-dependent DNA ligase from bacteriophage T7.
Cell(Cambridge,Mass.), 85, 1996
1UTU
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CRYSTAL STRUCTURE OF NOVEL PROTEIN EMSY TRUNCATE
Descriptor:EMSY
Authors:Chavali, G.B., Basu, B.P., Doherty, A.J.
Deposit date:2003-12-10
Release date:2005-10-13
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of Emsy to Hp1Beta: Implications for Recruitment of Hp1Beta and Bs69.
Embo Rep., 6, 2005
1UZ3
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CRYSTAL STRUCTURE OF NOVEL PROTEIN EMSY
Descriptor:EMSY PROTEIN
Authors:Chavali, G.B., Basu, B.P., Doherty, A.J.
Deposit date:2004-03-03
Release date:2005-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal Structure of the Ent Domain of Human Emsy.
J.Mol.Biol., 350, 2005
4LIT
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STRUCTURE OF YCFD A RIBOSOMAL OXYGENASE FROM ESCHERICHIA COLI IN COMPLEX WITH COBALT AND 2-OXOGLUTARATE.
Descriptor:50S ribosomal protein L16 arginine hydroxylase, COBALT (II) ION, 2-OXOGLUTARIC ACID
Authors:Brissett, N.C., Doherty, A.J.
Deposit date:2013-07-03
Release date:2014-05-14
Last modified:2014-07-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 509, 2014
4LIU
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STRUCTURE OF YCFD, A RIBOSOMAL OXYGENASE FROM ESCHERICHIA COLI.
Descriptor:50S ribosomal protein L16 arginine hydroxylase, TRIS(HYDROXYETHYL)AMINOMETHANE, PHOSPHATE ION
Authors:Brissett, N.C., Doherty, A.J., Fox, G.C.
Deposit date:2013-07-03
Release date:2014-05-14
Last modified:2014-07-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 509, 2014
4LIV
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STRUCTURE OF YCFD, A RIBOSOMAL OXYGENASE FROM ESCHERICHIA COLI IN COMPLEX WITH COBALT AND SUCCINIC ACID.
Descriptor:50S ribosomal protein L16 arginine hydroxylase, COBALT (II) ION, SUCCINIC ACID
Authors:Brissett, N.C., Doherty, A.J.
Deposit date:2013-07-03
Release date:2014-05-14
Last modified:2014-07-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 509, 2014
4MKY
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POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH AN ANNEALED DOUBLE-STRAND DNA BREAK.
Descriptor:DNA ligase-like protein Rv0938/MT0965, 5'-D(P*DGP*DCP*DGP*DGP*DC)-3', 5'-D(*DGP*DCP*DCP*DGP*DCP*DAP*DGP*DTP*DAP*DC)-3'
Authors:Brissett, N.C., Doherty, A.J.
Deposit date:2013-09-05
Release date:2013-12-11
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA Polymerase.
Cell Rep, 5, 2013
5DMP
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STRUCTURE OF THE ARCHAEAL NHEJ PHOSPHOESTERASE FROM METHANOCELLA PALUDICOLA.
Descriptor:Uncharacterized protein, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
Authors:Brissett, N.C., Bartlett, E.J., Doherty, A.J.
Deposit date:2015-09-09
Release date:2015-10-07
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:Molecular basis for DNA strand displacement by NHEJ repair polymerases.
Nucleic Acids Res., 44, 2016
5DMU
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STRUCTURE OF THE NHEJ POLYMERASE FROM METHANOCELLA PALUDICOLA
Descriptor:NHEJ Polymerase, 1,2-ETHANEDIOL, GLYCEROL, ...
Authors:Brissett, N.C., Bartlett, E.J., Doherty, A.J.
Deposit date:2015-09-09
Release date:2015-10-07
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Molecular basis for DNA strand displacement by NHEJ repair polymerases.
Nucleic Acids Res., 44, 2016
5N85
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STRUCTURE OF RPA70N IN COMPLEX WITH PRIMPOL (FRAGMENT 514-525)
Descriptor:Replication protein A 70 kDa DNA-binding subunit, DNA-directed primase/polymerase protein
Authors:Brissett, N.C., Doherty, A.J.
Deposit date:2017-02-23
Release date:2017-06-07
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for PrimPol recruitment to replication forks by RPA.
Nat Commun, 8, 2017
5N8A
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STRUCTURE OF RPA70N IN COMPLEX WITH PRIMPOL (FRAGMENT 480-560)
Descriptor:DNA-directed primase/polymerase protein, Replication protein A 70 kDa DNA-binding subunit
Authors:Brissett, N.C., Doherty, A.J.
Deposit date:2017-02-23
Release date:2017-06-07
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Molecular basis for PrimPol recruitment to replication forks by RPA.
Nat Commun, 8, 2017
5OP0
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STRUCTURE OF PRIM-POLC FROM MYCOBACTERIUM SMEGMATIS
Descriptor:DNA polymerase LigD, polymerase domain
Authors:Brissett, N.C., Doherty, A.J.
Deposit date:2017-08-09
Release date:2017-11-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria.
Nat Commun, 8, 2017
1CKO
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STRUCTURE OF MRNA CAPPING ENZYME IN COMPLEX WITH THE CAP ANALOG GPPPG
Descriptor:MRNA CAPPING ENZYME, ZINC ION, DIGUANOSINE-5'-TRIPHOSPHATE
Authors:Hakansson, K., Wigley, D.B.
Deposit date:1997-09-06
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a complex between a cap analogue and mRNA guanylyl transferase demonstrates the structural chemistry of RNA capping.
Proc.Natl.Acad.Sci.USA, 95, 1998
2QS3
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CRYSTAL STRUCTURE OF THE GLUR5 LIGAND BINDING CORE DIMER IN COMPLEX WITH UBP316 AT 1.76 ANGSTROMS RESOLUTION
Descriptor:Glutamate receptor, ionotropic kainate 1, CHLORIDE ION, ...
Authors:Alushin, G.M., Jane, D.E., Mayer, M.L.
Deposit date:2007-07-30
Release date:2008-08-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:ACET is a highly potent and specific kainate receptor antagonist: characterisation and effects on hippocampal mossy fibre function.
Neuropharmacology, 56, 2009
2XDV
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF FLJ14393
Descriptor:MYC-INDUCED NUCLEAR ANTIGEN, N-OXALYLGLYCINE, NICKEL (II) ION, ...
Authors:Krojer, T., Muniz, J.R.C., Ng, S.S., Pilka, E., Guo, K., Pike, A.C.W., Filippakopoulos, P., Knapp, S., Kavanagh, K.L., Gileadi, O., Bunkoczi, G., Yue, W.W., Niesen, F., Sobott, F., Fedorov, O., Savitsky, P., Kochan, G., Daniel, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U.
Deposit date:2010-05-07
Release date:2010-05-26
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
4BU2
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60S RIBOSOMAL PROTEIN L27A HISTIDINE HYDROXYLASE (MINA53) IN COMPLEX WITH NI(II) AND 2-OXOGLUTARATE (2OG)
Descriptor:BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA, NICKEL (II) ION, 2-OXOGLUTARIC ACID, ...
Authors:Chowdhury, R., Clifton, I.J., McDonough, M.A., Ng, S.S., Pilka, E., Oppermann, U., Schofield, C.J.
Deposit date:2013-06-19
Release date:2014-05-14
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
4BXF
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60S RIBOSOMAL PROTEIN L27A HISTIDINE HYDROXYLASE (MINA53 Y209C) IN COMPLEX WITH MN(II), 2-OXOGLUTARATE (2OG) AND 60S RIBOSOMAL PROTEIN L27A (RPL27A G37C) PEPTIDE FRAGMENT
Descriptor:BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA, 60S RIBOSOMAL PROTEIN L27A, MANGANESE (II) ION, ...
Authors:Chowdhury, R., Schofield, C.J.
Deposit date:2013-07-10
Release date:2014-05-14
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
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