Author results

6H5Q
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CRYO-EM STRUCTURE OF IN VITRO ASSEMBLED MEASLES VIRUS N INTO NUCLEOCAPSID-LIKE PARTICLES (NCLPS) BOUND TO POLYA RNA HEXAMERS.
Descriptor:Nucleocapsid, RNA (5'-R(*AP*AP*AP*AP*AP*A)-3')
Authors:Desfosses, A., Milles, S., Ringkjobing Jensen, M., Guseva, S., Colletier, J., Maurin, D., Schoehn, G., Gutsche, I., Ruigrok, R., Blackledge, M.
Deposit date:2018-07-25
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication.
Proc. Natl. Acad. Sci. U.S.A., 2019
6RAO
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CRYO-EM STRUCTURE OF THE ANTI-FEEDING PROPHAGE (AFP) BASEPLATE, 6-FOLD SYMMETRISED
Descriptor:Afp1, Afp2, Afp3, ...
Authors:Desfosses, A.
Deposit date:2019-04-06
Release date:2019-04-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of the anti-feeding prophage (AFP) baseplate, 6-fold symmetrised
To Be Published
6RAP
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CRYO-EM STRUCTURE OF THE ANTI-FEEDING PROPHAGE CAP (AFP TUBE TERMINATING CAP)
Descriptor:Afp1, Afp2, Afp3, ...
Authors:Desfosses, A.
Deposit date:2019-04-07
Release date:2019-04-17
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Atomic structures of an entire contractile injection system in both the extended and contracted states
To Be Published
6RC8
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CRYO-EM STRUCTURE OF THE ANTI-FEEDING PROPHAGE (AFP) HELICAL SHEATH IN CONTRACTED STATE
Descriptor:Afp2, Afp3
Authors:Desfosses, A.
Deposit date:2019-04-11
Release date:2019-04-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic structures of an entire contractile injection system in both the extended and contracted states
To Be Published
4CBU
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM ACTIN I
Descriptor:ACTIN-1, GELSOLIN, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Vahokoski, J., Bhargav, S.P., Desfosses, A., Andreadaki, M., Kumpula, E.P., Ignatev, A., Munico Martinez, S., Lepper, S., Frischknecht, F., Siden-Kiamos, I., Sachse, C., Kursula, I.
Deposit date:2013-10-16
Release date:2014-04-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Differences Explain Diverse Functions of Plasmodium Actins.
Plos Pathog., 10, 2014
4CBW
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CRYSTAL STRUCTURE OF PLASMODIUM BERGHEI ACTIN I WITH D-LOOP FROM MUSCLE ACTIN
Descriptor:ACTIN, ALPHA SKELETAL MUSCLE, GELSOLIN, ...
Authors:Vahokoski, J., Bhargav, S.P., Desfosses, A., Andreadaki, M., Kumpula, E.P., Ignatev, A., Munico Martinez, S., Lepper, S., Frischknecht, F., Siden-Kiamos, I., Sachse, C., Kursula, I.
Deposit date:2013-10-17
Release date:2014-04-30
Last modified:2017-03-15
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structural Differences Explain Diverse Functions of Plasmodium Actins.
Plos Pathog., 10, 2014
4CBX
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CRYSTAL STRUCTURE OF PLASMODIUM BERGHEI ACTIN II
Descriptor:ACTIN-2, GELSOLIN, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Vahokoski, J., Bhargav, S.P., Desfosses, A., Andreadaki, M., Kumpula, E.P., Ignatev, A., Munico Martinez, S., Lepper, S., Frischknecht, F., Siden-Kiamos, I., Sachse, C., Kursula, I.
Deposit date:2013-10-17
Release date:2014-04-30
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Differences Explain Diverse Functions of Plasmodium Actins.
Plos Pathog., 10, 2014
5AHV
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CRYO-EM STRUCTURE OF HELICAL ANTH AND ENTH TUBULES ON PI(4,5)P2-CONTAINING MEMBRANES
Descriptor:ENTH DOMAIN OF EPSIN ENT1, ANTH DOMAIN OF ENDOCYTIC ADAPTOR SLA2
Authors:Skruzny, M., Desfosses, A., Prinz, S., Dodonova, S.O., Gieras, A., Uetrecht, C., Jakobi, A.J., Abella, M., Hagen, W.J.H., Schulz, J., Meijers, R., Rybin, V., Briggs, J.A.G., Sachse, C., Kaksonen, M.
Deposit date:2015-02-10
Release date:2015-05-06
Last modified:2017-08-09
Method:ELECTRON MICROSCOPY (13.6 Å)
Cite:An Organized Co-Assembly of Clathrin Adaptors is Essential for Endocytosis.
Dev.Cell, 33, 2015
6GGS
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STRUCTURE OF RIP2 CARD FILAMENT
Descriptor:Receptor-interacting serine/threonine-protein kinase 2
Authors:Pellegrini, E., Cusack, S., Desfosses, A., Schoehn, G., Malet, H., Gutsche, I., Sachse, C., Hons, M.
Deposit date:2018-05-03
Release date:2018-10-17
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling.
Nat Commun, 9, 2018
4UFT
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STRUCTURE OF THE HELICAL MEASLES VIRUS NUCLEOCAPSID
Descriptor:NUCLEOPROTEIN, 5'-R(*CP*CP*CP*CP*CP*CP)-3'
Authors:Gutsche, I., Desfosses, A., Effantin, G., Ling, W.L., Haupt, M., Ruigrok, R.W.H., Sachse, C., Schoehn, G.
Deposit date:2015-03-19
Release date:2015-04-29
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Near-Atomic Cryo-Em Structure of the Helical Measles Virus Nucleocapsid.
Science, 348, 2015
6GK2
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HELICAL RECONSTRUCTION OF BCL10 CARD AND MALT1 DEATH DOMAIN COMPLEX
Descriptor:B-cell lymphoma/leukemia 10, Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Authors:Schlauderer, F., Desfosses, A., Gutsche, I., Hopfner, K.P., Lammens, K.
Deposit date:2018-05-18
Release date:2018-10-31
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Molecular architecture and regulation of BCL10-MALT1 filaments.
Nat Commun, 9, 2018
6I2N
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HELICAL RNA-BOUND HANTAAN VIRUS NUCLEOCAPSID
Descriptor:RNA (5'-R(P*UP*UP*U)-3'), Nucleoprotein
Authors:Arragain, B., Reguera, J., Desfosses, A., Gutsche, I., Schoehn, G., Malet, H.
Deposit date:2018-11-01
Release date:2019-01-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms.
Elife, 8, 2019
3QS7
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CRYSTAL STRUCTURE OF A HUMAN FLT3 LIGAND-RECEPTOR TERNARY COMPLEX
Descriptor:SL cytokine, FL cytokine receptor, N-ACETYL-D-GLUCOSAMINE
Authors:Verstraete, K., Savvides, S.N.
Deposit date:2011-02-19
Release date:2011-03-16
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex.
Blood, 118, 2011
3QS9
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CRYSTAL STRUCTURE OF A HUMAN FLT3 LIGAND-RECEPTOR TERNARY COMPLEX
Descriptor:SL cytokine, FL cytokine receptor
Authors:Verstraete, K., Savvides, S.N.
Deposit date:2011-02-20
Release date:2011-03-16
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (7.8 Å)
Cite:Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex.
Blood, 118, 2011
5M2N
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CRYSTAL STRUCTURE OF ELONGATOR SUBUNIT ELP2
Descriptor:Elongator complex protein 2
Authors:Glatt, S., Mueller, C.W.
Deposit date:2016-10-13
Release date:2016-12-28
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.812 Å)
Cite:Architecture of the yeast Elongator complex.
EMBO Rep., 18, 2017
6GFJ
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STRUCTURE OF RIP2 CARD DOMAIN FUSED TO CRYSTALLISABLE MBP TAG
Descriptor:Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2, MALTOSE
Authors:Pellegrini, E., Cusack, S.
Deposit date:2018-04-30
Release date:2019-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling.
Nat Commun, 9, 2018
5JCG
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STRUCTURE OF HUMAN PEROXIREDOXIN 3 AS THREE STACKED RINGS
Descriptor:Thioredoxin-dependent peroxide reductase, mitochondrial
Authors:Yewdall, N.A., Gerrard, J.A., Goldstone, D.C.
Deposit date:2016-04-15
Release date:2016-05-25
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Human Peroxiredoxin 3 Suggest Self-Chaperoning Assembly that Maintains Catalytic State.
Structure, 24, 2016