Author results

6TAA
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STRUCTURE AND MOLECULAR MODEL REFINEMENT OF ASPERGILLUS ORYZAE (TAKA) ALPHA-AMYLASE: AN APPLICATION OF THE SIMULATED-ANNEALING METHOD
Descriptor:ALPHA-AMYLASE, CALCIUM ION
Authors:Swift, H.J., Brady, L., Derewenda, Z.S., Dodson, E.J., Turkenburg, J.P., Wilkinson, A.J.
Deposit date:1992-08-21
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and molecular model refinement of Aspergillus oryzae (TAKA) alpha-amylase: an application of the simulated-annealing method.
Acta Crystallogr.,Sect.B, 47, 1991
6B6Z
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CRYSTAL STRUCTURE OF THE APO ANTIBODY FRAGMENT (FAB) RAISED AGAINST C-TERMINAL DOMAIN OF EBOLA NUCLEOPROTEIN (EBOV, TAFV, BDBV STRAINS)
Descriptor:Apo Fab Light Chain, Apo Fab Heavy Chain, ZINC ION
Authors:Radwanska, M.J., Derewenda, U., Kossiakoff, A.A., Derewenda, Z.S.
Deposit date:2017-10-03
Release date:2018-12-19
Method:X-RAY DIFFRACTION (2.112 Å)
Cite:Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains)
To Be Published
5W2B
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CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF EBOLA (RESTON) NUCLEOPROTEIN IN COMPLEX WITH FAB FRAGMENT
Descriptor:Fab Heavy Chain, Fab Light Chain, Nucleoprotein
Authors:Radwanska, M.J., Derewenda, U., Kossiakoff, A.A., Derewenda, Z.S.
Deposit date:2017-06-06
Release date:2018-06-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of C-terminal domain of Ebola (Reston) nucleoprotein in complex with Fab fragment
To Be Published
5VZ1
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CRYSTAL STRUCTURE OF THE APO ANTIBODY FRAGMENT (FAB) RAISED AGAINST C-TERMINAL DOMAIN OF EBOLA NUCLEOPROTEIN (EBOV, TAFV, BDBV STRAINS)
Descriptor:Apo Antibody Fab Light Chain, Apo Antibody Fab Heavy Chain, ZINC ION
Authors:Radwanska, M.J., Derewenda, U., Kossiakoff, A., Derewenda, Z.S.
Deposit date:2017-05-26
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.112 Å)
Cite:Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains)
To Be Published
5VKD
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CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF EBOLA (BUNDIBUGYO) NUCLEOPROTEIN IN COMPLEX WITH FAB FRAGMENT
Descriptor:Nucleoprotein, Fab Heavy Chain, Fab light chain
Authors:Radwanska, M.J., Derewenda, U., Kossiakoff, A., Derewenda, Z.S.
Deposit date:2017-04-21
Release date:2018-04-25
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment
To Be Published
5VIM
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CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS5 METHYLTRANSFERASE.
Descriptor:Methyltransferase, S-ADENOSYLMETHIONINE, SULFATE ION
Authors:Bukrejewska, M., Derewenda, Z.S., Derewenda, U.
Deposit date:2017-04-17
Release date:2017-09-06
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain.
Acta Crystallogr D Struct Biol, 73, 2017
5VI7
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CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS3 HELICASE
Descriptor:helicase, SULFATE ION
Authors:Bukrejewska, M., Derewenda, U., Derewenda, Z.S.
Deposit date:2017-04-14
Release date:2017-09-06
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain.
Acta Crystallogr D Struct Biol, 73, 2017
5TGL
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A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX
Descriptor:LIPASE, N-HEXYLPHOSPHONATE ETHYL ESTER
Authors:Brzozowski, A.M., Derewenda, U., Derewenda, Z.S., Dodson, G.G., Lawson, D., Turkenburg, J.P., Bjorkling, F., Huge-Jensen, B., Patkar, S.R., Thim, L.
Deposit date:1991-10-30
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex.
Nature, 351, 1991
5E2X
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THE CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF EBOLA (TAI FOREST) NUCLEOPROTEIN
Descriptor:NP, NONAETHYLENE GLYCOL
Authors:Baker, L.E., Handing, K.B., Derewenda, U., Utepbergenov, D., Derewenda, Z.S.
Deposit date:2015-10-01
Release date:2015-10-21
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses.
Acta Crystallogr D Struct Biol, 72, 2016
5DSD
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THE CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF EBOLA (BUNDIBUGYO) NUCLEOPROTEIN
Descriptor:Nucleoprotein, GLYCEROL, CHLORIDE ION
Authors:Baker, L., Handing, K.B., Utepbergenov, D., Derewenda, U., Derewenda, Z.S.
Deposit date:2015-09-17
Release date:2015-09-30
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses.
Acta Crystallogr D Struct Biol, 72, 2016
4TGL
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CATALYSIS AT THE INTERFACE: THE ANATOMY OF A CONFORMATIONAL CHANGE IN A TRIGLYCERIDE LIPASE
Descriptor:TRIACYL-GLYCEROL ACYLHYDROLASE, DIETHYL PHOSPHONATE
Authors:Derewenda, U., Brzozowski, A.M., Lawson, D., Derewenda, Z.S.
Deposit date:1991-07-29
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase.
Biochemistry, 31, 1992
4QB0
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THE CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF EBOLA (ZAIRE) NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Derewenda, U., Dziubanska, P.J., Derewenda, Z.S.
Deposit date:2014-05-06
Release date:2014-09-10
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structure of the C-terminal domain of the Zaire ebolavirus nucleoprotein.
Acta Crystallogr.,Sect.D, 70, 2014
4QAZ
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THE CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF EBOLA (ZAIRE) NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Derewenda, U., Dziubanska, P.J., Derewenda, Z.S.
Deposit date:2014-05-06
Release date:2014-09-10
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The structure of the C-terminal domain of the Zaire ebolavirus nucleoprotein.
Acta Crystallogr.,Sect.D, 70, 2014
4GUE
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STRUCTURE OF N-TERMINAL KINASE DOMAIN OF RSK2 WITH FLAVONOID GLYCOSIDE QUERCITRIN
Descriptor:Ribosomal protein S6 kinase alpha-3, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, MAGNESIUM ION, ...
Authors:Derewenda, U., Utepbergenov, D., Szukalska, G., Derewenda, Z.S.
Deposit date:2012-08-29
Release date:2013-01-30
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 69, 2013
4EL9
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STRUCTURE OF N-TERMINAL KINASE DOMAIN OF RSK2 WITH AFZELIN
Descriptor:Ribosomal protein S6 kinase alpha-3, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside
Authors:Utepbergenov, D., Derewenda, U., Derewenda, Z.S.
Deposit date:2012-04-10
Release date:2012-09-05
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Insights into the Inhibition of the p90 Ribosomal S6 Kinase (RSK) by the Flavonol Glycoside SL0101 from the 1.5 A Crystal Structure of the N-Terminal Domain of RSK2 with Bound Inhibitor.
Biochemistry, 51, 2012
3ZQD
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B. SUBTILIS L,D-TRANSPEPTIDASE
Descriptor:L, D-TRANSPEPTIDASE YKUD
Authors:Lecoq, L., Simorre, J.-P., Bougault, C., Arthur, M., Hugonnet, J.-E., Veckerle, C., Pessey, O.
Deposit date:2011-06-09
Release date:2012-05-23
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Dynamics Induced by Beta-Lactam Antibiotics in the Active Site of Bacillus subtilis L,D-Transpeptidase.
Structure, 20, 2012
3UBD
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STRUCTURE OF N-TERMINAL DOMAIN OF RSK2 KINASE IN COMPLEX WITH FLAVONOID GLYCOSIDE SL0101
Descriptor:Ribosomal protein S6 kinase alpha-3, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 3,4-di-O-acetyl-6-deoxy-alpha-L-mannopyranoside
Authors:Utepbergenov, D., Derewenda, U., Derewenda, Z.S.
Deposit date:2011-10-24
Release date:2012-09-05
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Insights into the Inhibition of the p90 Ribosomal S6 Kinase (RSK) by the Flavonol Glycoside SL0101 from the 1.5 A Crystal Structure of the N-Terminal Domain of RSK2 with Bound Inhibitor.
Biochemistry, 51, 2012
3TV0
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STRUCTURE OF DYNACTIN P27 SUBUNIT
Descriptor:Dynactin subunit 6
Authors:Derewenda, Z.S., Derewenda, U., Kowalska, A.
Deposit date:2011-09-19
Release date:2012-10-03
Method:X-RAY DIFFRACTION (2.1492 Å)
Cite:Dynactin targets Polo-like kinase 1 to kinetochores
To be Published
3TGL
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STRUCTURE AND MOLECULAR MODEL REFINEMENT OF RHIZOMUCOR MIEHEI TRIACYLGLYCERIDE LIPASE: A CASE STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT
Descriptor:TRIACYL-GLYCEROL ACYLHYDROLASE
Authors:Brady, L., Brzozowski, A.M., Derewenda, Z.S., Dodson, E.J., Dodson, G.G., Tolley, S.P., Turkenburg, J.P., Christiansen, L., Huge-Jensen, B., Norskov, L., Thim, L.
Deposit date:1991-07-29
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:STRUCTURE AND MOLECULAR-MODEL REFINEMENT OF RHIZOMUCOR-MIEHEI TRIACYLGLYCERIDE LIPASE - A CASE-STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT.
Acta Crystallogr.,Sect.B, 48, 1992
3T06
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CRYSTAL STRUCTURE OF THE DH/PH FRAGMENT OF PDZRHOGEF WITH N-TERMINAL REGULATORY ELEMENTS IN COMPLEX WITH HUMAN RHOA
Descriptor:Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
Authors:Bielnicki, J.A., Derewenda, U., Derewenda, Z.S.
Deposit date:2011-07-19
Release date:2011-08-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Insights into the Molecular Activation Mechanism of the RhoA-specific Guanine Nucleotide Exchange Factor, PDZRhoGEF.
J.Biol.Chem., 286, 2011
3SXZ
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METAL-FREE FCD DOMAIN OF TM0439 A PUTATIVE TRANSCRIPTIONAL REGULATOR
Descriptor:Transcriptional regulator, GntR family
Authors:Czelakowski, G.P., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2011-07-15
Release date:2011-11-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.322 Å)
Cite:Metal-free FCD domain of TM0439 a putative transcriptional regulator
To be Published
3SXY
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METAL-FREE FULL-LENGTH STRUCTURE OF TM0439, A METAL-BINDING FCD FAMILY TRANSCRIPTIONAL REGULATOR
Descriptor:Transcriptional regulator, GntR family
Authors:Czelakowski, G.P., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2011-07-15
Release date:2011-11-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.647 Å)
Cite:Metal-free full-length structure of Tm0439, a metal-binding FCD family transcriptional regulator
To be Published
3SXM
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METAL-FREE FCD DOMAIN OF TM0439 A PUTATIVE TRANSCRIPTIONAL REGULATOR
Descriptor:Transcriptional regulator, GntR family, BICARBONATE ION
Authors:Czelakowski, G.P., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2011-07-15
Release date:2011-11-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Metal-free FCD domain of TM0439 a putative transcriptional regulator
To be Published
3SXK
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ZN2+-BOUND FCD DOMAIN OF TM0439, A PUTATIVE TRANSCRIPTIONAL REGULATOR
Descriptor:Transcriptional regulator, GntR family, SULFATE ION, ...
Authors:Czelakowski, G.P., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2011-07-15
Release date:2011-11-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Zn2+-bound FCD domain of TM0439, a putative transcriptional regulator
To be Published
3QOR
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CRYSTAL STRUCTURE OF HUMAN NUCLEAR MIGRATION PROTEIN NUDC
Descriptor:Nuclear migration protein nudC, ACETATE ION
Authors:Derewenda, U., Derewenda, Z., Zheng, M.
Deposit date:2011-02-10
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.753 Å)
Cite:Structural Features and Chaperone Activity of the NudC Protein Family.
J.Mol.Biol., 409, 2011