2KVY
| NMR solution structure of the 4:1 complex between an uncharged distamycin A analogue and [d(TGGGGT)]4 | Descriptor: | 4-amino-1-methyl-N-{1-methyl-5-[(1-methyl-5-{[3-(methylamino)-3-oxopropyl]carbamoyl}-1H-pyrrol-3-yl)carbamoyl]-1H-pyrrol-3-yl}-1H-pyrrole-2-carboxamide, DNA (5'-D(*TP*GP*GP*GP*GP*T)-3') | Authors: | Cosconati, S, Marinelli, L, Trotta, R, Virno, A, De Tito, S, Romagnoli, R, Pagano, B, Limongelli, V, Giancola, C, Baraldi, P, Mayol, L, Novellino, E, Randazzo, A. | Deposit date: | 2010-03-29 | Release date: | 2010-05-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle. J.Am.Chem.Soc., 132, 2010
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6I9B
| NMR structure of the La module from human LARP4A | Descriptor: | La-related protein 4 | Authors: | Conte, M.R, Martino, L, Atkinson, R.A, Kelly, G, Cruz-Gallardo, I, De Tito, S, Trotta, R. | Deposit date: | 2018-11-22 | Release date: | 2019-03-13 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA. Nucleic Acids Res., 47, 2019
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7PNL
| Complex between monomolecular human telomeric G-quadruplex and a sulfonamide derivative of the natural alkaloid Berberine | Descriptor: | 4-[[1-[3-[(17-methoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2(10),3,8,13,15,17,19-octaen-16-yl)oxy]propyl]triazol-4-yl]methoxy]benzenesulfonamide, G-guadruplex DNA (23-mer), POTASSIUM ION | Authors: | Bazzicalupi, C, Gratteri, P, Petreni, A, Nocentini, A. | Deposit date: | 2021-09-07 | Release date: | 2022-09-21 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Development of a multi-targeted chemotherapeutic approach based on G-quadruplex stabilisation and carbonic anhydrase inhibition. J Enzyme Inhib Med Chem, 39, 2024
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8POE
| Structure of tissue-specific lipid scramblase ATG9B homotrimer, refined with C3 symmetry applied | Descriptor: | Autophagy-related protein 9B | Authors: | Chiduza, G.N, Pye, V.E, Tooze, S.A, Cherepanov, P. | Deposit date: | 2023-07-04 | Release date: | 2023-11-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | ATG9B is a tissue-specific homotrimeric lipid scramblase that can compensate for ATG9A. Autophagy, 20, 2024
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