Author results

2BXR
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HUMAN MONOAMINE OXIDASE A IN COMPLEX WITH CLORGYLINE, CRYSTAL FORM A
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] A, FLAVIN-ADENINE DINUCLEOTIDE, N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE
Authors:De Colibus, L., Binda, C., Edmondson, D.E., Mattevi, A.
Deposit date:2005-07-27
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B
Proc.Natl.Acad.Sci.USA, 102, 2005
2BXS
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HUMAN MONOAMINE OXIDASE A IN COMPLEX WITH CLORGYLINE, CRYSTAL FORM B
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] A, FLAVIN-ADENINE DINUCLEOTIDE, N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE
Authors:De Colibus, L., Binda, C., Edmondson, D.E., Mattevi, A.
Deposit date:2005-07-27
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Three-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B
Proc.Natl.Acad.Sci.USA, 102, 2005
3ZX7
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COMPLEX OF LYSENIN WITH PHOSPHOCHOLINE
Descriptor:LYSENIN, PHOSPHATE ION, PHOSPHOCHOLINE, ...
Authors:De Colibus, L., Sonnen, A.F.P., Morris, K.J., Siebert, C.A., Abrusci, P., Plitzko, J., Hodnik, V., Leippe, M., Volpi, E., Anderluh, G., Gilbert, R.J.C.
Deposit date:2011-08-08
Release date:2012-09-19
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins and its Mode of Sphingomyelin Recognition.
Structure, 20, 2012
3ZXD
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WILD-TYPE LYSENIN
Descriptor:LYSENIN, GLYCEROL, SULFATE ION, ...
Authors:De Colibus, L., Sonnen, A.F.P., Morris, K.J., Siebert, C.A., Abrusci, P., Plitzko, J., Hodnik, V., Leippe, M., Volpi, E., Anderluh, G., Gilbert, R.J.C.
Deposit date:2011-08-09
Release date:2012-09-19
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins and its Mode of Sphingomyelin Recognition.
Structure, 20, 2012
3ZXG
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LYSENIN SPHINGOMYELIN COMPLEX
Descriptor:LYSENIN, SULFATE ION, TRIMETHYL-[2-[[(2S,3S)-2-(OCTADECANOYLAMINO)-3-OXIDANYL-BUTOXY]-OXIDANYL-PHOSPHORYL]OXYETHYL]AZANIUM
Authors:De Colibus, L., Sonnen, A.F.P., Morris, K.J., Siebert, C.A., Abrusci, P., Plitzko, J., Hodnik, V., Leippe, M., Volpi, E., Anderluh, G., Gilbert, R.J.C.
Deposit date:2011-08-10
Release date:2012-09-19
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins and its Mode of Sphingomyelin Recognition.
Structure, 20, 2012
4CDU
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP3
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-06
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4CDW
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP4
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-06
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4CDX
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP12
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-07
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules.
Nat.Struct.Mol.Biol., 21, 2014
4CEW
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR ALD
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-12
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules.
Nat.Struct.Mol.Biol., 21, 2014
4CEY
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR NLD
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-12
Release date:2014-02-12
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
5ABJ
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STRUCTURE OF COXSACKIEVIRUS A16 IN COMPLEX WITH GPP3
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Tijsma, A., Neyts, J., Spyrou, J.A.B., Ren, J., Grimes, J.M., Puerstinger, G., Leyssen, P., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2015-08-06
Release date:2015-09-09
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure Elucidation of Coxsackievirus A16 in Complex with Gpp3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses.
Plos Pathog., 11, 2015
2BYB
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HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH DEPRENYL
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, DEPRENYL
Authors:Binda, C., De Colibus, L., Edmondson, D.E., Mattevi, A.
Deposit date:2005-07-29
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B
Proc.Natl.Acad.Sci.USA, 102, 2005
5OAC
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FLIP MAJOR CAPSID PROTEIN
Descriptor:Major capsid protein
Authors:De Colibus, L., Stuart, D.I., Huiskonen, J.T.
Deposit date:2017-06-21
Release date:2017-07-26
Last modified:2017-08-09
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Virus found in a boreal lake links ssDNA and dsDNA viruses.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2V6I
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KOKOBERA VIRUS HELICASE
Descriptor:RNA HELICASE, PYROPHOSPHATE 2-
Authors:Speroni, S., De Colibus, L., Coutard, B., Canard, B., Mattevi, A.
Deposit date:2007-07-18
Release date:2008-03-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008
2V6J
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KOKOBERA VIRUS HELICASE: MUTANT MET47THR
Descriptor:RNA HELICASE
Authors:Speroni, S., De Colibus, L., Coutard, B., Canard, B., Mattevi, A.
Deposit date:2007-07-18
Release date:2008-03-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008
4BBK
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STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF THE KINDLIN-1 PLECKSTRIN HOMOLOGY DOMAIN
Descriptor:FERMITIN FAMILY HOMOLOG 1, GLYCEROL
Authors:Yates, L.A., Lumb, C.N., Brahme, N.N., Zalyte, R., Bird, L.E., De Colibus, L., Owens, R.J., Calderwood, D.A., Sansom, M.S.P., Gilbert, R.J.C.
Deposit date:2012-09-25
Release date:2012-11-14
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain
J.Biol.Chem., 287, 2012
5O8F
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STRUCTURE OF A CHIMAERIC BETA3-ALPHA5 GABAA RECEPTOR IN COMPLEX WITH NANOBODY NB25 AND PREGNANOLONE
Descriptor:Gamma-aminobutyric acid receptor subunit beta-3,Gamma-aminobutyric acid receptor subunit alpha-5,Gamma-aminobutyric acid receptor subunit alpha-5, Nanobody Nb25, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Miller, P.S., Scott, S., Masiulis, S., De Colibus, L., Pardon, E., Steyaert, J., Aricescu, A.R.
Deposit date:2017-06-13
Release date:2017-11-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for GABAA receptor potentiation by neurosteroids.
Nat. Struct. Mol. Biol., 24, 2017
5OJM
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STRUCTURE OF A CHIMAERIC BETA3-ALPHA5 GABAA RECEPTOR IN COMPLEX WITH NANOBODY NB25
Descriptor:Human GABAA receptor chimera beta3-alpha5,Gamma-aminobutyric acid receptor subunit beta-3,Gamma-aminobutyric acid receptor subunit alpha-5, Nanobody Nb25, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Miller, P.S., Scott, S., Masiulis, S., De Colibus, L., Pardon, E., Steyaert, J., Aricescu, A.R.
Deposit date:2017-07-21
Release date:2017-10-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for GABAA receptor potentiation by neurosteroids.
Nat. Struct. Mol. Biol., 24, 2017
6QT9
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CRYO-EM STRUCTURE OF SH1 FULL PARTICLE.
Descriptor:ORF 25, ORF 24, ORF 31, ...
Authors:De Colibus, L., Roine, E., Walter, T.S., Ilca, S.L., Wang, X., Wang, N., Roseman, A.M., Bamford, D., Huiskonen, J.T., Stuart, D.I.
Deposit date:2019-02-22
Release date:2019-04-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Assembly of complex viruses exemplified by a halophilic euryarchaeal virus.
Nat Commun, 10, 2019
4CDQ
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP2
Descriptor:VP1, VP2, VP3, ...
Authors:DeColibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-05
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4E7X
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STRUCTURAL BASIS FOR THE ACTIVITY OF A CYTOPLASMIC RNA TERMINAL U-TRANSFERASE
Descriptor:Poly(A) RNA polymerase protein cid1, ACETATE ION
Authors:Yates, L.A., Fleurdepine, S., Rissland, O.S., DeColibus, L., Harlos, K., Norbury, C.J., Gilbert, R.J.C.
Deposit date:2012-03-19
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase.
Nat.Struct.Mol.Biol., 19, 2012
4E80
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STRUCTURAL BASIS FOR THE ACTIVITY OF A CYTOPLASMIC RNA TERMINAL U-TRANSFERASE
Descriptor:Poly(A) RNA polymerase protein cid1, URIDINE 5'-TRIPHOSPHATE
Authors:Yates, L.A., Fleurdepine, S., Rissland, O.S., DeColibus, L., Harlos, K., Norbury, C.J., Gilbert, R.J.C.
Deposit date:2012-03-19
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase.
Nat.Struct.Mol.Biol., 19, 2012
4E8F
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STRUCTURAL BASIS FOR THE ACTIVITY OF A CYTOPLASMIC RNA TERMINAL U-TRANSFERASE
Descriptor:Poly(A) RNA polymerase protein cid1, ACETATE ION, GLYCEROL
Authors:Yates, L.A., Fleurdepine, S., Rissland, O.S., DeColibus, L., Harlos, K., Norbury, C.J., Gilbert, R.J.C.
Deposit date:2012-03-20
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase.
Nat.Struct.Mol.Biol., 19, 2012
5LWY
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REVISED CRYSTAL STRUCTURE OF THE HUMAN ADIPONECTIN RECEPTOR 2 IN COMPLEX WITH A C18 FREE FATTY ACID
Descriptor:Adiponectin receptor protein 2, V REGION HEAVY CHAIN, V REGION LIGHT CHAIN, ...
Authors:Leyrat, C., Vasiliauskaite-Brooks, I., Granier, S.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into adiponectin receptors suggest ceramidase activity.
Nature, 6, 2017
5LX9
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CRYSTAL STRUCTURE OF HUMAN ADIPONECTIN RECEPTOR 2 IN COMPLEX WITH A C18 FREE FATTY ACID AT 2.4 ANGSTROM RESOLUTION
Descriptor:HUMAN ADIPONECTIN RECEPTOR 2, single-chain variable fragment, ZINC ION, ...
Authors:Vasiliauskaite-Brooks, I., Leyrat, C., Hoh, F., Granier, S.
Deposit date:2016-09-20
Release date:2017-03-22
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into adiponectin receptors suggest ceramidase activity.
Nature, 6, 2017
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