Author results

2NXB
  • Download 2nxb
  • View 2nxb
Molmil generated image of 2nxb
CRYSTAL STRUCTURE OF HUMAN BROMODOMAIN CONTAINING PROTEIN 3 (BRD3)
Descriptor:Bromodomain-containing protein 3, SODIUM ION, 1,2-ETHANEDIOL
Authors:Filippakopoulos, P., Bullock, A., Cooper, C., Keates, K., Berridge, G., Pike, A., Bunkoczi, G., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2006-11-17
Release date:2006-12-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
2OBV
  • Download 2obv
  • View 2obv
Molmil generated image of 2obv
CRYSTAL STRUCTURE OF THE HUMAN S-ADENOSYLMETHIONINE SYNTHETASE 1 IN COMPLEX WITH THE PRODUCT
Descriptor:S-adenosylmethionine synthetase isoform type-1, SODIUM ION, S-ADENOSYLMETHIONINE, ...
Authors:Pilka, E.S., Shafqat, N., Kavanagh, K.L., Cooper, C., Hozjan, V., Turnbull, A., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-12-20
Release date:2007-01-02
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product.
To be Published
2OO1
  • Download 2oo1
  • View 2oo1
Molmil generated image of 2oo1
CRYSTAL STRUCTURE OF THE BROMO DOMAIN 2 OF HUMAN BROMODOMAIN CONTAINING PROTEIN 3 (BRD3)
Descriptor:Bromodomain-containing protein 3, SODIUM ION, 1,2-ETHANEDIOL, ...
Authors:Filippakopoulos, P., Bullock, A., Papagrigoriou, E., Keates, T., Cooper, C., Smee, C., Ugochukwu, E., Debreczeni, J., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2007-01-25
Release date:2007-02-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
2PN8
  • Download 2pn8
  • View 2pn8
Molmil generated image of 2pn8
CRYSTAL STRUCTURE OF HUMAN PEROXIREDOXIN 4 (THIOREDOXIN PEROXIDASE)
Descriptor:Peroxiredoxin-4
Authors:Pilka, E.S., Kavanagh, K.L., Cooper, C., von Delft, F., Sundstrom, M., Arrowsmith, C.A., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-04-24
Release date:2007-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase).
To be Published
2PNT
  • Download 2pnt
  • View 2pnt
Molmil generated image of 2pnt
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN GRASP (GRP1) IN COMPLEX WITH THE C-TERMINAL PEPTIDE OF THE METABOTROPIC GLUTAMATE RECEPTOR TYPE 1
Descriptor:General receptor for phosphoinositides 1-associated scaffold protein, CHLORIDE ION
Authors:Elkins, J., Papagrigoriou, E., Cooper, C., Gileadi, C., Uppenberg, J., Bray, J., von Delft, F., Pike, A.C.W., Ugochukwu, E., Umeano, C., Gileadi, O., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-04-25
Release date:2007-05-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1.
To be Published
2Q9V
  • Download 2q9v
  • View 2q9v
Molmil generated image of 2q9v
CRYSTAL STRUCTURE OF THE C890S MUTANT OF THE 4TH PDZ DOMAIN OF HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASE
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
Authors:Pilka, E.S., Hozjan, V., Kavanagh, K.L., Papagrigoriou, E., Cooper, C., Elkins, J.M., Doyle, D.A., von Delft, F., Sundstrom, M., Arrowsmith, C.A., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-06-14
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase.
To be Published
2JII
  • Download 2jii
  • View 2jii
Molmil generated image of 2jii
STRUCTURE OF VACCINIA RELATED KINASE 3
Descriptor:SERINE/THREONINE-PROTEIN KINASE VRK3 MOLECULE: VACCINIA RELATED KINASE 3, 1,2-ETHANEDIOL
Authors:Bunkoczi, G., Eswaran, J., Pike, A.C.W., Uppenberg, J., Ugochukwu, E., von Delft, F., Cooper, C., Salah, E., Savitsky, P., Burgess-Brown, N., Keates, T., Fedorov, O., Sobott, F., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., Knapp, S.
Deposit date:2007-06-28
Release date:2007-07-10
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site.
Structure, 17, 2009
2JIK
  • Download 2jik
  • View 2jik
Molmil generated image of 2jik
CRYSTAL STRUCTURE OF PDZ DOMAIN OF SYNAPTOJANIN-2 BINDING PROTEIN
Descriptor:SYNAPTOJANIN-2 BINDING PROTEIN
Authors:Tickle, J., Phillips, C., Pike, A.C.W., Cooper, C., Salah, E., Elkins, J., Turnbull, A.P., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.
Deposit date:2007-06-28
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal Structure of Pdz Domain of Synaptojanin-2 Binding Protein
To be Published
2JIL
  • Download 2jil
  • View 2jil
Molmil generated image of 2jil
CRYSTAL STRUCTURE OF 2ND PDZ DOMAIN OF GLUTAMATE RECEPTOR INTERACTING PROTEIN-1 (GRIP1)
Descriptor:GLUTAMATE RECEPTOR INTERACTING PROTEIN-1, THIOCYANATE ION, 1,2-ETHANEDIOL
Authors:Tickle, J., Elkins, J., Pike, A.C.W., Cooper, C., Salah, E., Papagrigoriou, E., von Delft, F., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.
Deposit date:2007-06-28
Release date:2007-07-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of 2Nd Pdz Domain of Glutamate Receptor Interacting Protein-1 (Grip1)
To be Published
2JIN
  • Download 2jin
  • View 2jin
Molmil generated image of 2jin
CRYSTAL STRUCTURE OF PDZ DOMAIN OF SYNAPTOJANIN-2 BINDING PROTEIN
Descriptor:SYNAPTOJANIN-2 BINDING PROTEIN, SODIUM ION, SULFATE ION
Authors:Tickle, J., Phillips, C., Pike, A.C.W., Cooper, C., Salah, E., Elkins, J., Turnbull, A.P., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.
Deposit date:2007-06-28
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of Pdz Domain of Synaptojanin-2 Binding Protein
To be Published
2V62
  • Download 2v62
  • View 2v62
Molmil generated image of 2v62
STRUCTURE OF VACCINIA-RELATED KINASE 2
Descriptor:SERINE/THREONINE-PROTEIN KINASE VRK2, MAGNESIUM ION, SUCCINIC ACID, ...
Authors:Bunkoczi, G., Eswaran, J., Cooper, C., Fedorov, O., Keates, T., Rellos, P., Salah, E., Savitsky, P., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., Knapp, S.
Deposit date:2007-07-13
Release date:2007-08-21
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the Pseudokinase Vrk3 Reveals a Degraded Catalytic Site, a Highly Conserved Kinase Fold, and a Putative Regulatory Binding Site.
Structure, 17, 2009
2V90
  • Download 2v90
  • View 2v90
Molmil generated image of 2v90
CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF INTESTINE- AND KIDNEY- ENRICHED PDZ DOMAIN IKEPP (PDZD3)
Descriptor:PDZ DOMAIN-CONTAINING PROTEIN 3, SULFATE ION
Authors:Uppenberg, J., Gileadi, C., Phillips, C., Elkins, J., Bunkoczi, G., Cooper, C., Pike, A.C.W., Salah, E., Ugochukwu, E., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., Doyle, D.A.
Deposit date:2007-08-16
Release date:2007-08-28
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the 3Rd Pdz Domain of Intestine- and Kidney-Enriched Pdz Domain Ikepp (Pdzd3)
To be Published
2R4H
  • Download 2r4h
  • View 2r4h
Molmil generated image of 2r4h
CRYSTAL STRUCTURE OF A C1190S MUTANT OF THE 6TH PDZ DOMAIN OF HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASE
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, HISTIDINE
Authors:Ugochukwu, E., Pilka, E.S., Hozjan, V., Kavanagh, K.L., Cooper, C., Pike, A.C.W., Elkins, J.M., Doyle, D.A., von Delft, F., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-08-31
Release date:2007-10-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of a C1190S mutant of the 6th PDZ domain of human membrane associated guanylate kinase.
To be Published
2REY
  • Download 2rey
  • View 2rey
Molmil generated image of 2rey
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN DISHEVELLED 2 (HOMOLOGOUS TO DROSOPHILA DSH)
Descriptor:Segment polarity protein dishevelled homolog DVL-2
Authors:Papagrigoriou, E., Gileadi, C., Elkins, J., Cooper, C., Ugochukwu, E., Turnbull, A., Pike, A.C.W., Gileadi, O., von Delft, F., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2007-09-27
Release date:2007-10-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of the PDZ domains of human dishevelled 2 (homologous to Drosophila dsh).
To be Published
3B84
  • Download 3b84
  • View 3b84
Molmil generated image of 3b84
CRYSTAL STRUCTURE OF THE HUMAN BTB DOMAIN OF THE KRUEPPEL RELATED ZINC FINGER PROTEIN 3 (HKR3)
Descriptor:Zinc finger and BTB domain-containing protein 48, UNKNOWN, 1,2-ETHANEDIOL
Authors:Filippakopoulos, P., Bullock, A., Cooper, C., Keates, T., Salah, E., Pilka, E., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2007-10-31
Release date:2007-11-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal Structure of the Human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3).
To be Published
3BKB
  • Download 3bkb
  • View 3bkb
Molmil generated image of 3bkb
CRYSTAL STRUCTURE OF HUMAN FELINE SARCOMA VIRAL ONCOGENE HOMOLOGUE (V-FES)
Descriptor:Proto-oncogene tyrosine-protein kinase Fes/Fps, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Filippakopoulos, P., Salah, E., Fedorov, O., Cooper, C., Ugochukwu, E., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2007-12-06
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation
Cell(Cambridge,Mass.), 134, 2008
3BPU
  • Download 3bpu
  • View 3bpu
Molmil generated image of 3bpu
CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASE, C677S AND C709S DOUBLE MUTANT
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, ZINC ION
Authors:Pilka, E.S., Hozjan, V., Cooper, C., Pike, A.C.W., Elkins, J., Doyle, D.A., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-12-19
Release date:2008-01-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the 3rd PDZ domain of human membrane associated guanylate kinase, C677S and C709S double mutant.
To be Published
3CBL
  • Download 3cbl
  • View 3cbl
Molmil generated image of 3cbl
CRYSTAL STRUCTURE OF HUMAN FELINE SARCOMA VIRAL ONCOGENE HOMOLOGUE (V-FES) IN COMPLEX WITH STAUROSPORINE AND A CONSENSUS PEPTIDE
Descriptor:Proto-oncogene tyrosine-protein kinase Fes/Fps, Synthetic peptide, STAUROSPORINE
Authors:Filippakopoulos, P., Salah, E., Cooper, C., Picaud, S.S., Elkins, J.M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2008-02-22
Release date:2008-03-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation
Cell(Cambridge,Mass.), 134, 2008
3CD3
  • Download 3cd3
  • View 3cd3
Molmil generated image of 3cd3
CRYSTAL STRUCTURE OF PHOSPHORYLATED HUMAN FELINE SARCOMA VIRAL ONCOGENE HOMOLOGUE (V-FES) IN COMPLEX WITH STAUROSPORINE AND A CONSENSUS PEPTIDE
Descriptor:Proto-oncogene tyrosine-protein kinase Fes/Fps, Synthetic peptide, CHLORIDE ION, ...
Authors:Filippakopoulos, P., Salah, E., Cooper, C., Picaud, S.S., Elkins, J.M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2008-02-26
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation
Cell(Cambridge,Mass.), 134, 2008
2VRF
  • Download 2vrf
  • View 2vrf
Molmil generated image of 2vrf
CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN
Descriptor:BETA-2-SYNTROPHIN, 1,2-ETHANEDIOL
Authors:Sun, Z., Roos, A.K., Pike, A.C.W., Pilka, E.S., Cooper, C., Elkins, J.M., Murray, J., Arrowsmith, C.H., Doyle, D., Edwards, A., von Delft, F., Bountra, C., Oppermann, U.
Deposit date:2008-03-31
Release date:2008-04-22
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Human Beta-2-Syntrophin Pdz Domain
To be Published
2VSP
  • Download 2vsp
  • View 2vsp
Molmil generated image of 2vsp
CRYSTAL STRUCTURE OF THE FOURTH PDZ DOMAIN OF PDZ DOMAIN-CONTAINING PROTEIN 1
Descriptor:PDZ DOMAIN-CONTAINING PROTEIN 1
Authors:Yue, W.W., Shafqat, N., Pilka, E.S., Johansson, C., Murray, J.W., Elkins, J., Roos, A., Cooper, C., Phillips, C., Salah, E., von Delft, F., Doyle, D., Edwards, A., Wikstrom, M., Arrowsmith, C., Bountra, C., Oppermann, U.
Deposit date:2008-04-28
Release date:2009-03-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal Structure of the Fourth Pdz Domain of Pdz Domain-Containing Protein 1
To be Published
2VZ5
  • Download 2vz5
  • View 2vz5
Molmil generated image of 2vz5
STRUCTURE OF THE PDZ DOMAIN OF TAX1 (HUMAN T-CELL LEUKEMIA VIRUS TYPE I) BINDING PROTEIN 3
Descriptor:TAX1-BINDING PROTEIN 3, IMIDAZOLE, ZINC ION, ...
Authors:Murray, J.W., Shafqat, N., Yue, W., Pilka, E., Johannsson, C., Salah, E., Cooper, C., Elkins, J.M., Pike, A.C., Roos, A., Filippakopoulos, P., von Delft, F., Wickstroem, M., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Oppermann, U.
Deposit date:2008-07-30
Release date:2008-08-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.738 Å)
Cite:The Structure of the Pdz Domain of Tax1BP
To be Published
3EPU
  • Download 3epu
  • View 3epu
Molmil generated image of 3epu
CRYSTAL STRUCTURE OF STM2138, A NOVEL VIRULENCE CHAPERONE IN SALMONELLA
Descriptor:STM2138 Virulence Chaperone
Authors:Zhang, K., Andres, S.N., Hannemann, M., Coombes, B., Junop, M.
Deposit date:2008-09-30
Release date:2009-09-29
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis and quantitative proteomic interactome of a novel virulence chaperone in Salmonella
To be Published
2W4F
  • Download 2w4f
  • View 2w4f
Molmil generated image of 2w4f
CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN SCRIB1
Descriptor:PROTEIN LAP4, 1,2-ETHANEDIOL
Authors:Hozjan, V., Pilka, E.S., Roos, A.K., W Yue, W., Phillips, C., Bray, J., Cooper, C., Salah, E., Elkins, J.M., Muniz, J.R.C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., von Delft, F., Bountra, C., Doyle, D.A., Oppermann, U.
Deposit date:2008-11-25
Release date:2008-12-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structure of the First Pdz Domain of Human Scrib1
To be Published
3GGE
  • Download 3gge
  • View 3gge
Molmil generated image of 3gge
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PDZ DOMAIN-CONTAINING PROTEIN GIPC2
Descriptor:PDZ domain-containing protein GIPC2, SULFATE ION, GLYCEROL
Authors:Chaikuad, A., Hozjan, V., Yue, W., Cooper, C., Elkins, J., Pike, A.C.W., Roos, A.K., Filippakopoulos, P., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2009-02-27
Release date:2009-03-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the PDZ domain of PDZ domain-containing protein GIPC2
To be Published
<12>