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1LCI
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BU of 1lci by Molmil
FIREFLY LUCIFERASE
Descriptor: LUCIFERASE
Authors:Conti, E, Franks, N.P, Brick, P.
Deposit date:1996-06-01
Release date:1997-03-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes.
Structure, 4, 1996
2FAM
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BU of 2fam by Molmil
X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES
Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION
Authors:Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M.
Deposit date:1993-07-20
Release date:1993-10-31
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states.
J.Mol.Biol., 233, 1993
2FAL
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BU of 2fal by Molmil
X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES
Descriptor: CYANIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M.
Deposit date:1993-06-14
Release date:1993-10-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states.
J.Mol.Biol., 233, 1993
1EE5
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BU of 1ee5 by Molmil
YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A NUCLEOPLASMIN NLS PEPTIDE
Descriptor: KARYOPHERIN ALPHA, NUCLEOPLASMIN
Authors:Conti, E.
Deposit date:2000-01-30
Release date:2000-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Structure Fold.Des., 8, 2000
1BCU
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BU of 1bcu by Molmil
ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN
Descriptor: ALPHA-THROMBIN, HIRUGEN, PROFLAVIN
Authors:Conti, E, Rivetti, C, Wonacott, A, Brick, P.
Deposit date:1998-05-02
Release date:1998-10-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin.
FEBS Lett., 425, 1998
1EE4
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BU of 1ee4 by Molmil
CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A C-MYC NLS PEPTIDE
Descriptor: KARYOPHERIN ALPHA, MYC PROTO-ONCOGENE PROTEIN
Authors:Conti, E.
Deposit date:2000-01-30
Release date:2000-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Structure Fold.Des., 8, 2000
1AMU
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BU of 1amu by Molmil
PHENYLALANINE ACTIVATING DOMAIN OF GRAMICIDIN SYNTHETASE 1 IN A COMPLEX WITH AMP AND PHENYLALANINE
Descriptor: ADENOSINE MONOPHOSPHATE, GRAMICIDIN SYNTHETASE 1, MAGNESIUM ION, ...
Authors:Conti, E, Stachelhaus, T, Marahiel, M.A, Brick, P.
Deposit date:1997-06-18
Release date:1998-07-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S.
EMBO J., 16, 1997
1BK6
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BU of 1bk6 by Molmil
KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS
Descriptor: KARYOPHERIN ALPHA, LARGE T ANTIGEN
Authors:Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
Deposit date:1998-07-14
Release date:1999-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
1BK5
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BU of 1bk5 by Molmil
KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE
Descriptor: COBALT (II) ION, KARYOPHERIN ALPHA
Authors:Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
Deposit date:1998-07-14
Release date:1999-01-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
8RXB
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BU of 8rxb by Molmil
Human UPF1 CH domain in complex with SMG6 peptide
Descriptor: Regulator of nonsense transcripts 1, Telomerase-binding protein EST1A, ZINC ION
Authors:Langer, L, Basquin, J, Conti, E.
Deposit date:2024-02-06
Release date:2024-05-15
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2.
Nucleic Acids Res., 52, 2024
4U4C
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BU of 4u4c by Molmil
The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities
Descriptor: 1,2-ETHANEDIOL, ATP-dependent RNA helicase DOB1, CHLORIDE ION, ...
Authors:Falk, S, Weir, J.R, Hentschel, J, Reichelt, P, Bonneau, F, Conti, E.
Deposit date:2014-07-23
Release date:2014-09-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities.
Mol.Cell, 55, 2014
2J0S
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BU of 2j0s by Molmil
The crystal structure of the Exon Junction Complex at 2.2 A resolution
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP *UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ...
Authors:Bono, F, Ebert, J, Lorentzen, E, Conti, E.
Deposit date:2006-08-04
Release date:2006-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The Crystal Structure of the Exon Junction Complex Reveals How It Mantains a Stable Grip on Mrna
Cell(Cambridge,Mass.), 126, 2006
6YVH
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BU of 6yvh by Molmil
CWC22-CWC27-EIF4A3 Complex
Descriptor: Eukaryotic initiation factor 4A-III, Pre-mRNA-splicing factor CWC22 homolog, Spliceosome-associated protein CWC27 homolog
Authors:Basquin, J, Busetto, V, LeHir, H, Conti, E.
Deposit date:2020-04-28
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.
Nucleic Acids Res., 48, 2020
5JNB
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BU of 5jnb by Molmil
structure of GLD-2/RNP-8 complex
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Poly(A) RNA polymerase gld-2, ...
Authors:Nakel, K, Bonneau, F, Basquin, C, Eckmann, C.R, Conti, E.
Deposit date:2016-04-29
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.486 Å)
Cite:Structural basis for the antagonistic roles of RNP-8 and GLD-3 in GLD-2 poly(A)-polymerase activity.
Rna, 22, 2016
1BA3
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BU of 1ba3 by Molmil
FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Descriptor: LUCIFERASE, TRIBROMOMETHANE
Authors:Franks, N.P, Jenkins, A, Conti, E, Lieb, W.R, Brick, P.
Deposit date:1998-04-21
Release date:1998-11-11
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the inhibition of firefly luciferase by a general anesthetic.
Biophys.J., 75, 1998
5JEA
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BU of 5jea by Molmil
Structure of a cytoplasmic 11-subunit RNA exosome complex including Ski7, bound to RNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Exosome complex component CSL4, Exosome complex component MTR3, ...
Authors:Kowalinski, E, Ebert, J, Stegmann, E, Conti, E.
Deposit date:2016-04-18
Release date:2016-07-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex.
Mol.Cell, 63, 2016
4UM2
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BU of 4um2 by Molmil
Crystal structure of the TPR domain of SMG6
Descriptor: GLYCEROL, TELOMERASE-BINDING PROTEIN EST1A
Authors:Chakrabarti, S, Bonneau, F, Schuessler, S, Eppinger, E, Conti, E.
Deposit date:2014-05-14
Release date:2014-07-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Phospho-Dependent and Phospho-Independent Interactions of the Helicase Upf1 with the Nmd Factors Smg5-Smg7 and Smg6.
Nucleic Acids Res., 42, 2014
4W8W
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BU of 4w8w by Molmil
Crystal structure of oligomeric Cmr4 from Pyrococcus furiosus
Descriptor: CRISPR system Cmr subunit Cmr4
Authors:Benda, C, Ebert, J, Baumgaertner, M, Conti, E.
Deposit date:2014-08-26
Release date:2014-10-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4.
Mol.Cell, 56, 2014
3N89
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BU of 3n89 by Molmil
KH domains
Descriptor: Defective in germ line development protein 3, isoform a
Authors:Nakel, K, Hartung, S.A, Bonneau, F, Eckmann, C.R, Conti, E.
Deposit date:2010-05-28
Release date:2010-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform.
Rna, 16, 2010
1W3B
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BU of 1w3b by Molmil
The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Descriptor: CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110
Authors:Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E.
Deposit date:2004-07-14
Release date:2004-09-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
2QFA
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BU of 2qfa by Molmil
Crystal structure of a Survivin-Borealin-INCENP core complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Baculoviral IAP repeat-containing protein 5, Borealin, ...
Authors:Jeyaprakash, A.A, Klein, U.R, Lindner, D, Ebert, J, Nigg, E.A, Conti, E.
Deposit date:2007-06-27
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of a Survivin-Borealin-INCENP Core Complex Reveals How Chromosomal Passengers Travel Together.
Cell(Cambridge,Mass.), 131, 2007
1YA0
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BU of 1ya0 by Molmil
Crystal structure of the N-terminal domain of human SMG7
Descriptor: SMG-7 transcript variant 2, SULFATE ION
Authors:Fukuhara, N, Ebert, J, Unterholzner, L, Lindner, D, Izaurralde, E, Conti, E.
Deposit date:2004-12-17
Release date:2005-03-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:SMG7 Is a 14-3-3-like Adaptor in the Nonsense-Mediated mRNA Decay Pathway.
Mol.Cell, 17, 2005
4CT5
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BU of 4ct5 by Molmil
DDX6
Descriptor: ACETATE ION, DDX6
Authors:Ozgur, S, Basquin, J, Conti, E.
Deposit date:2014-03-12
Release date:2014-05-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression.
Mol.Cell, 54, 2014
4CT6
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BU of 4ct6 by Molmil
CNOT9-CNOT1 complex
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG
Authors:Basquin, J, Ozgur, S, Conti, E.
Deposit date:2014-03-12
Release date:2014-05-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression.
Mol.Cell, 54, 2014
4N0L
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BU of 4n0l by Molmil
Methanopyrus kandleri Csm3 crystal structure
Descriptor: Predicted component of a thermophile-specific DNA repair system, contains a RAMP domain, ZINC ION
Authors:Hrle, A, Su, A.A, Ebert, J, Benda, C, Conti, E, Randau, L.
Deposit date:2013-10-02
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structure and RNA-binding properties of the Type III-A CRISPR-associated protein Csm3.
Rna Biol., 10, 2013

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