5NHQ
| Nuclear Magnetic Resonance Structure of the Human Polyoma JC Virus Agnoprotein | Descriptor: | Agnoprotein | Authors: | Coric, P, Saribas, A.S, Abou-Gharbia, M, Childers, W, Condra, J, White, M.K, Safak, M, Bouaziz, S. | Deposit date: | 2017-03-22 | Release date: | 2017-04-26 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Nuclear Magnetic Resonance Structure of the Human Polyoma JC Virus Agnoprotein. J. Cell. Biochem., 118, 2017
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2MJ2
| Structure of the dimerization domain of the human polyoma, JC virus agnoprotein is an amphipathic alpha-helix. | Descriptor: | Agnoprotein | Authors: | Coric, P, Saribas, S.A, Abou-Gharbia, M, Childers, W, White, M, Bouaziz, S, Safak, M. | Deposit date: | 2013-12-23 | Release date: | 2014-04-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The structure of the dimerization domain of the human polyoma, JC virus agnoprotein is an amphipathic alpha-helix J.Virol., 2014
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8GD7
| Loop Deleted DNA Polymerase Theta Polymerase Domain in Complex with Double Strand DNA Overhang and Inhibitor | Descriptor: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 2-(3-methyl-2-oxoimidazolidin-1-yl)-4,6-bis(trifluoromethyl)phenyl (4-fluorophenyl)methylcarbamate, DNA Primer, ... | Authors: | Fried, W.A, Chen, X.S, Li, S.X. | Deposit date: | 2023-03-03 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | Discovery of a small-molecule inhibitor that traps Pol theta on DNA and synergizes with PARP inhibitors. Nat Commun, 15, 2024
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6W9E
| Crystal Structure of Human CDK9/cyclinT1 in complex with MC180295 | Descriptor: | (4-amino-2-{[(1R,2R,4S)-bicyclo[2.2.1]heptan-2-yl]amino}-1,3-thiazol-5-yl)(2-nitrophenyl)methanone, (4-amino-2-{[(1S,2S,4R)-bicyclo[2.2.1]heptan-2-yl]amino}-1,3-thiazol-5-yl)(2-nitrophenyl)methanone, Cyclin-T1, ... | Authors: | Zhang, P, Wu, J. | Deposit date: | 2020-03-22 | Release date: | 2021-09-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Comparative Modeling of CDK9 Inhibitors to Explore Selectivity and Structure-Activity Relationships To Be Published
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