Search by PDB author

Crystal structure of human Pim-1 kinase in complex with an aminooxadiazole-indole inhibitor.
Descriptor:	GLYCEROL, N-tert-butyl-5-[3-(4-cyclopropylpyrimidin-2-yl)-1H-indol-5-yl]-1,3,4-oxadiazol-2-amine, Serine/threonine-protein kinase pim-1
Authors:	Mohr, C.
Deposit date:	2014-07-07
Release date:	2015-02-04
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015

Structure of AuroraA with pyridyl-pyrimidine urea inhibitor
Descriptor:	1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea, SULFATE ION, Serine/threonine-protein kinase 6
Authors:	Bellon, S.F, Cee, V, Hughes, P, Geuns-Meyer, S, Whittington, D.
Deposit date:	2008-09-10
Release date:	2008-12-23
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.29 Å)
Cite:	Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase. Bioorg.Med.Chem.Lett., 19, 2009