Author results

1HQM
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CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Minakhin, L., Bhagat, S., Brunning, A., Campbell, E.A., Darst, S.A., Ebright, R.H., Severinov, K.
Deposit date:2000-12-18
Release date:2001-02-07
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
Proc.Natl.Acad.Sci.USA, 98, 2001
1I6V
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THERMUS AQUATICUS CORE RNA POLYMERASE-RIFAMPICIN COMPLEX
Descriptor:DNA-DIRECTED RNA POLYMERASE, RIFAMPICIN, MAGNESIUM ION, ...
Authors:Campbell, E.A., Korzheva, N., Mustaev, A., Murakami, K., Goldfarb, A., Darst, S.A.
Deposit date:2001-03-05
Release date:2001-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural mechanism for rifampicin inhibition of bacterial rna polymerase.
Cell(Cambridge,Mass.), 104, 2001
1KU2
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CRYSTAL STRUCTURE OF THERMUS AQUATICUS RNA POLYMERASE SIGMA SUBUNIT FRAGMENT CONTAINING REGIONS 1.2 TO 3.1
Descriptor:sigma factor sigA, SULFATE ION
Authors:Campbell, E.A., Muzzin, O., Chlenov, M., Sun, J.L., Olson, C.A., Weinman, O., Trester-Zedlitz, M.L., Darst, S.A.
Deposit date:2002-01-21
Release date:2002-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
1KU3
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CRYSTAL STRUCTURE OF THERMUS AQUATICUS RNA POLYMERASE SIGMA SUBUNIT FRAGMENT, REGION 4
Descriptor:sigma factor sigA
Authors:Campbell, E.A., Muzzin, O., Chlenov, M., Sun, J.L., Olson, C.A., Weinman, O., Trester-Zedlitz, M.L., Darst, S.A.
Deposit date:2002-01-21
Release date:2002-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
1KU7
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CRYSTAL STRUCTURE OF THERMUS AQUATICS RNA POLYMERASE SIGMAA SUBUNIT REGION 4 BOUND TO-35 ELEMENT DNA
Descriptor:5'-D(*CP*CP*TP*TP*GP*AP*CP*AP*AP*AP*G)-3', 5'-D(*CP*CP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3', sigma factor sigA
Authors:Campbell, E.A., Muzzin, O., Chlenov, M., Sun, J.L., Olson, C.A., Weinman, O., Trester-Zedlitz, M.L., Darst, S.A.
Deposit date:2002-01-21
Release date:2002-03-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
1L0O
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CRYSTAL STRUCTURE OF THE BACILLUS STEAROTHERMOPHILUS ANTI-SIGMA FACTOR SPOIIAB WITH THE SPORULATION SIGMA FACTOR SIGMAF
Descriptor:Anti-sigma F factor, sigma factor, MAGNESIUM ION, ...
Authors:Campbell, E.A., Masuda, S., Sun, J.L., Muzzin, O., Olson, C.A., Wang, S., Darst, S.A.
Deposit date:2002-02-12
Release date:2002-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF.
Cell(Cambridge,Mass.), 108, 2002
1L9Z
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THERMUS AQUATICUS RNA POLYMERASE HOLOENZYME/FORK-JUNCTION PROMOTER DNA COMPLEX AT 6.5 A RESOLUTION
Descriptor:nontemplate DNA strand, template DNA strand, RNA POLYMERASE, ...
Authors:Murakami, K.S., Masuda, S., Campbell, E.A., Muzzin, O., Darst, S.A.
Deposit date:2002-03-27
Release date:2002-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex.
Science, 296, 2002
1OR7
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI SIGMAE WITH THE CYTOPLASMIC DOMAIN OF ITS ANTI-SIGMA RSEA
Descriptor:RNA polymerase sigma-E factor, Sigma-E factor negative regulatory protein
Authors:Campbell, E.A., Tupy, J.L., Gruber, T.M., Wang, S., Sharp, M.M., Gross, C.A., Darst, S.A.
Deposit date:2003-03-12
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA.
Mol.Cell, 11, 2003
1TH8
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CRYSTAL STRUCTURES OF THE ADP AND ATP BOUND FORMS OF THE BACILLUS ANTI-SIGMA FACTOR SPOIIAB IN COMPLEX WITH THE ANTI-ANTI-SIGMA SPOIIAA: INHIBITORY COMPLEX WITH ADP, CRYSTAL FORM II
Descriptor:Anti-sigma F factor, Anti-sigma F factor antagonist, MAGNESIUM ION, ...
Authors:Masuda, S., Murakami, K.S., Wang, S., Olson, C.A., Donigian, J., Leon, F., Darst, S.A., Campbell, E.A.
Deposit date:2004-06-01
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1THN
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CRYSTAL STRUCTURES OF THE ADP AND ATP BOUND FORMS OF THE BACILLUS ANTI-SIGMA FACTOR SPOIIAB IN COMPLEX WITH THE ANTI-ANTI-SIGMA SPOIIAA: INHIBITORY COMPLEX WITH ADP, CRYSTAL FORM I
Descriptor:Anti-sigma F factor, Anti-sigma F factor antagonist, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Masuda, S., Murakami, K.S., Wang, S., Olson, C.A., Donigan, J., Leon, F., Darst, S.A., Campbell, E.A.
Deposit date:2004-06-01
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1TID
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CRYSTAL STRUCTURES OF THE ADP AND ATP BOUND FORMS OF THE BACILLUS ANTI-SIGMA FACTOR SPOIIAB IN COMPLEX WITH THE ANTI-ANTI-SIGMA SPOIIAA: POISED FOR PHOSPHORYLATION COMPLEX WITH ATP, CRYSTAL FORM I
Descriptor:Anti-sigma F factor, Anti-sigma F factor antagonist, MAGNESIUM ION, ...
Authors:Masuda, S., Murakami, K.S., Wang, S., Olson, C.A., Donigan, J., Leon, F., Darst, S.A., Campbell, E.A.
Deposit date:2004-06-02
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1TIL
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CRYSTAL STRUCTURES OF THE ADP AND ATP BOUND FORMS OF THE BACILLUS ANTI-SIGMA FACTOR SPOIIAB IN COMPLEX WITH THE ANTI-ANTI-SIGMA SPOIIAA:POISED FOR PHOSPHORYLATION COMPLEX WITH ATP, CRYSTAL FORM II
Descriptor:Anti-sigma F factor, Anti-sigma F factor antagonist, MAGNESIUM ION, ...
Authors:Masuda, S., Murakami, K.S., Wang, S., Olson, C.A., Donigan, J., Leon, F., Darst, S.A., Campbell, E.A.
Deposit date:2004-06-02
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1YNJ
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TAQ RNA POLYMERASE-SORANGICIN COMPLEX
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Campbell, E.A., Pavlova, O., Zenkin, N., Leon, F., Irschik, H., Jansen, R., Severinov, K., Darst, S.A.
Deposit date:2005-01-24
Release date:2005-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
1YNN
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TAQ RNA POLYMERASE-RIFAMPICIN COMPLEX
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Campbell, E.A., Pavlova, O., Zenkin, N., Leon, F., Irschik, H., Jansen, R., Severinov, K., Darst, S.A.
Deposit date:2005-01-24
Release date:2005-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
2P7V
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CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI REGULATOR OF SIGMA 70, RSD, IN COMPLEX WITH SIGMA 70 DOMAIN 4
Descriptor:Regulator of sigma D, RNA polymerase sigma factor rpoD, MAGNESIUM ION
Authors:Patikoglou, G.A., Westblade, L.F., Campbell, E.A., Lamour, V., Lane, W.J., Darst, S.A.
Deposit date:2007-03-20
Release date:2007-08-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the Escherichia coli regulator of sigma70, Rsd, in complex with sigma70 domain 4.
J.Mol.Biol., 372, 2007
2Q1Z
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CRYSTAL STRUCTURE OF RHODOBACTER SPHAEROIDES SIGE IN COMPLEX WITH THE ANTI-SIGMA CHRR
Descriptor:RpoE, ECF SigE, Anti-Sigma factor ChrR, ...
Authors:Campbell, E.A., Darst, S.A.
Deposit date:2007-05-25
Release date:2007-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria.
Mol.Cell, 27, 2007
2Z2S
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CRYSTAL STRUCTURE OF RHODOBACTER SPHAEROIDES SIGE IN COMPLEX WITH THE ANTI-SIGMA CHRR
Descriptor:RpoE, ECF SigE, Anti-Sigma factor ChrR, ...
Authors:Darst, S.A., Campbell, E.A.
Deposit date:2007-05-26
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria.
Mol.Cell, 27, 2007
3GFK
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CRYSTAL STRUCTURE OF BACILLUS SUBTILIS SPX/RNA POLYMERASE ALPHA SUBUNIT C-TERMINAL DOMAIN COMPLEX
Descriptor:Regulatory protein spx, DNA-directed RNA polymerase subunit alpha
Authors:Lamour, V., Westblade, L.F., Campbell, E.A., Darst, S.A.
Deposit date:2009-02-27
Release date:2009-03-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the in vivo-assembled Bacillus subtilis Spx/RNA polymerase alpha subunit C-terminal domain complex
J.Struct.Biol., 168, 2009
3MLQ
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS TRANSCRIPTION-REPAIR COUPLING FACTOR RNA POLYMERASE INTERACTING DOMAIN WITH THE THERMUS AQUATICUS RNA POLYMERASE BETA1 DOMAIN
Descriptor:DNA-directed RNA polymerase subunit beta, Transcription-repair coupling factor, PHOSPHATE ION
Authors:Darst, S.A., Westblade, L.F., Campbell, E.A.
Deposit date:2010-04-18
Release date:2010-10-13
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction.
Nucleic Acids Res., 38, 2010
3NRX
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INSIGHTS INTO ANTI-PARALLEL MICROTUBULE CROSSLINKING BY PRC1, A CONSERVED NON-MOTOR MICROTUBULE BINDING PROTEIN
Descriptor:Protein regulator of cytokinesis 1
Authors:Kapoor, T.M., Subramanian, R., Wilson-Kubalek, E.M., Arthur, C.P., Bick, M.J., Campbell, E.A., Darst, S.A., Milligan, R.A.
Deposit date:2010-06-30
Release date:2010-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein.
Cell(Cambridge,Mass.), 142, 2010
3NRY
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INSIGHTS INTO ANTI-PARALLEL MICROTUBULE CROSSLINKING BY PRC1, A CONSERVED MICROTUBULE BINDING PROTEIN
Descriptor:Protein regulator of cytokinesis 1
Authors:Kapoor, T.M., Subramanian, R., Wilson-Kubalek, E.M., Arthur, C.P., Bick, M.J., Campbell, E.A., Darst, S.A., Milligan, R.A.
Deposit date:2010-07-01
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein.
Cell(Cambridge,Mass.), 142, 2010
3TBI
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CRYSTAL STRUCTURE OF T4 GP33 BOUND TO E. COLI RNAP BETA-FLAP DOMAIN
Descriptor:RNA polymerase-associated protein Gp33, DNA-directed RNA polymerase subunit beta
Authors:Twist, K.A.F., Campbell, E.A., Darst, S.A.
Deposit date:2011-08-06
Release date:2011-11-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of T4 gp33 bound to E. coli RNAP beta-flap domain
To be Published
4L5G
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS CARD
Descriptor:CarD
Authors:Srivastava, D.B., Westblade, L.F., Campbell, E.A., Darst, S.A.
Deposit date:2013-06-11
Release date:2013-07-31
Last modified:2013-08-21
Method:X-RAY DIFFRACTION (2.3902 Å)
Cite:Structure and function of CarD, an essential mycobacterial transcription factor.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LJZ
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CRYSTAL STRUCTURE ANALYSIS OF THE E.COLI HOLOENZYME
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Bae, B., Darst, S.A.
Deposit date:2013-07-05
Release date:2013-11-13
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (3.5871 Å)
Cite:Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LK0
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CRYSTAL STRUCTURE ANALYSIS OF THE E.COLI HOLOENZYME/T7 GP2 COMPLEX
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Bae, B., Darst, S.A.
Deposit date:2013-07-05
Release date:2013-11-13
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (3.9103 Å)
Cite:Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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