Author results

1QH5
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HUMAN GLYOXALASE II WITH S-(N-HYDROXY-N-BROMOPHENYLCARBAMOYL)GLUTATHIONE
Descriptor:PROTEIN (HYDROXYACYLGLUTATHIONE HYDROLASE), ZINC ION, GLUTATHIONE, ...
Authors:Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
Deposit date:1999-05-11
Release date:1999-09-24
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
2XVM
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CRYSTAL STRUCTURE OF THE TELLURITE DETOXIFICATION PROTEIN TEHB FROM E. COLI IN COMPLEX WITH SAH
Descriptor:TELLURITE RESISTANCE PROTEIN TEHB, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Choudhury, H.G., Cameron, A.D., Iwata, S., Beis, K.
Deposit date:2010-10-26
Release date:2011-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structure and Mechanism of the Chalcogen Detoxifying Protein Tehb from Escherichia Coli.
Biochem.J., 435, 2011
2JGB
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STRUCTURE OF HUMAN EIF4E HOMOLOGOUS PROTEIN 4EHP WITH M7GTP
Descriptor:EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE
Authors:Cameron, A.D., Rosettani, P., Knapp, S., Vismara, M.G., Rusconi, L.
Deposit date:2007-02-12
Release date:2007-02-27
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
J. Mol. Biol., 368, 2007
1QIP
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HUMAN GLYOXALASE I COMPLEXED WITH S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE
Descriptor:PROTEIN (LACTOYLGLUTATHIONE LYASE), ZINC ION, S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE, ...
Authors:Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
Deposit date:1999-06-14
Release date:1999-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38, 1999
1RKD
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E. COLI RIBOKINASE COMPLEXED WITH RIBOSE AND ADP
Descriptor:RIBOKINASE, RIBOSE, PHOSPHATE ION, ...
Authors:Sigrell, J.A., Cameron, A.D., Jones, T.A., Mowbray, S.L.
Deposit date:1997-11-29
Release date:1998-03-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structure of Escherichia coli ribokinase in complex with ribose and dinucleotide determined to 1.8 A resolution: insights into a new family of kinase structures.
Structure, 6, 1998
6H7B
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STRUCTURE OF LEISHMANIA PABP1 (DOMAIN J) COMPLEXED WITH A PEPTIDE CONTAINING THE PAM2 MOTIF OF EIF4E4.
Descriptor:Polyadenylate-binding protein, HIS-HIS-MET-ASN-PRO-ASN-ALA-THR-GLU-PHE-MET-PRO
Authors:Cameron, A.D., Firczuk, H., dos Santos Rodrigues, F.H., McCarthy, J.E.G.
Deposit date:2018-07-31
Release date:2018-12-12
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The Leishmania PABP1-eIF4E4 interface: a novel 5'-3' interaction architecture for trans-spliced mRNAs.
Nucleic Acids Res., 47, 2019
1H8V
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THE X-RAY CRYSTAL STRUCTURE OF THE TRICHODERMA REESEI FAMILY 12 ENDOGLUCANASE 3, CEL12A, AT 1.9 A RESOLUTION
Descriptor:ENDO-BETA-1,4-GLUCANASE, N-ACETYL-D-GLUCOSAMINE
Authors:Sandgren, M., Shaw, A., Ropp, T.H., Wu, S., Bott, R., Cameron, A.D., Stahlberg, J., Mitchinson, C., Jones, T.A.
Deposit date:2001-02-16
Release date:2001-04-24
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The X-Ray Crystal Structure of the Trichoderma Reesei Family 12 Endoglucanase 3, Cel12A, at 1.9 A Resolution
J.Mol.Biol., 308, 2001
1QH3
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HUMAN GLYOXALASE II WITH CACODYLATE AND ACETATE IONS PRESENT IN THE ACTIVE SITE
Descriptor:PROTEIN (HYDROXYACYLGLUTATHIONE HYDROLASE), ZINC ION, CACODYLATE ION, ...
Authors:Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
Deposit date:1999-05-10
Release date:1999-09-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
2XVA
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CRYSTAL STRUCTURE OF THE TELLURITE DETOXIFICATION PROTEIN TEHB FROM E. COLI IN COMPLEX WITH SINEFUNGIN
Descriptor:TELLURITE RESISTANCE PROTEIN TEHB, SINEFUNGIN, ZINC ION
Authors:Choudhury, H.G., Cameron, A.D., Iwata, S., Beis, K.
Deposit date:2010-10-25
Release date:2011-02-16
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Mechanism of the Chalcogen Detoxifying Protein Tehb from Escherichia Coli.
Biochem.J., 435, 2011
6FV4
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THE STRUCTURE OF N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE DEACETYLASE D267A MUTANT FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE
Descriptor:N-acetylglucosamine-6-phosphate deacetylase, ZINC ION, N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE, ...
Authors:Ahangar, M.S., Furze, C.M., Guy, C.S., Cooper, C., Maskew, K.S., Graham, B., Cameron, A.D., Fullam, E.
Deposit date:2018-03-01
Release date:2018-05-16
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.974 Å)
Cite:Structural and functional determination of homologs of theMycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA).
J. Biol. Chem., 293, 2018
1GSE
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GLUTATHIONE TRANSFERASE A1-1 COMPLEXED WITH AN ETHACRYNIC ACID GLUTATHIONE CONJUGATE (MUTANT R15K)
Descriptor:GLUTATHIONE TRANSFERASE, GLUTATHIONE, ETHACRYNIC ACID, ...
Authors:Cameron, A.D., Jones, T.A.
Deposit date:1995-06-09
Release date:1995-09-15
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate.
Structure, 3, 1995
1QIN
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HUMAN GLYOXALASE I COMPLEXED WITH S-(N-HYDROXY-N-P-IODOPHENYLCARBAMOYL) GLUTATHIONE
Descriptor:PROTEIN (LACTOYLGLUTATHIONE LYASE), ZINC ION, S-(N-HYDROXY-N-IODOPHENYLCARBAMOYL)GLUTATHIONE
Authors:Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
Deposit date:1999-06-14
Release date:1999-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38, 1999
2J4Z
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STRUCTURE OF AURORA-2 IN COMPLEX WITH PHA-680626
Descriptor:SERINE THREONINE-PROTEIN KINASE 6, 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE, ARSENIC
Authors:Cameron, A.D., Izzo, G., Storici, P., Rusconi, L., Fancelli, D., Varasi, M., Berta, D., Bindi, S., Forte, B., Severino, D., Tonani, R., Vianello, P.
Deposit date:2006-09-08
Release date:2006-11-06
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.
J. Med. Chem., 49, 2006
6H7A
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STRUCTURE OF LEISHMANIA PABP1 (DOMAIN J).
Descriptor:PABP1 domain J
Authors:Cameron, A.D., Firczuk, H., dos Santos Rodrigues, F.H., McCarthy, J.E.G.
Deposit date:2018-07-31
Release date:2018-12-12
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The Leishmania PABP1-eIF4E4 interface: a novel 5'-3' interaction architecture for trans-spliced mRNAs.
Nucleic Acids Res., 47, 2019
1MNI
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ALTERATION OF AXIAL COORDINATION BY PROTEIN ENGINEERING IN MYOGLOBIN. BIS-IMIDAZOLE LIGATION IN THE HIS64-->VAL(SLASH)VAL68-->HIS DOUBLE MUTANT
Descriptor:MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Krzywda, S., Wilkinson, A.J.
Deposit date:1995-01-11
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Alteration of axial coordination by protein engineering in myoglobin. Bisimidazole ligation in the His64-->Val/Val68-->His double mutant.
J.Biol.Chem., 270, 1995
1YCB
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DISTAL POCKET POLARITY IN LIGAND BINDING TO MYOGLOBIN: DEOXY AND CARBONMONOXY FORMS OF A THREONINE68 (E11) MUTANT INVESTIGATED BY X-RAY CRYSTALLOGRAPHY AND INFRARED SPECTROSCOPY
Descriptor:MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Cameron, A.D., Smerdon, S.J., Wilkinson, A.J., Habash, J., Helliwell, J.R.
Deposit date:1993-08-10
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Biochemistry, 32, 1993
3AIE
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CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS
Descriptor:Glucosyltransferase-SI, CALCIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Ito, K., Ito, S., Shimamura, T., Iwata, S.
Deposit date:2010-05-12
Release date:2011-03-23
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of glucansucrase from the dental caries pathogen Streptococcus mutans.
J.Mol.Biol., 408, 2011
1BH5
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HUMAN GLYOXALASE I Q33E, E172Q DOUBLE MUTANT
Descriptor:LACTOYLGLUTATHIONE LYASE, ZINC ION, S-HEXYLGLUTATHIONE
Authors:Cameron, A.D., Jones, T.A.
Deposit date:1998-06-13
Release date:1998-11-04
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Involvement of an active-site Zn2+ ligand in the catalytic mechanism of human glyoxalase I.
J.Biol.Chem., 273, 1998
1FRO
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HUMAN GLYOXALASE I WITH BENZYL-GLUTATHIONE INHIBITOR
Descriptor:LACTOYLGLUTATHIONE LYASE, ZINC ION, S-BENZYL-GLUTATHIONE
Authors:Cameron, A.D., Jones, T.A.
Deposit date:1997-02-25
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of human glyoxalase I--evidence for gene duplication and 3D domain swapping.
EMBO J., 16, 1997
1MNJ
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INTERACTIONS AMONG RESIDUES CD3, E7, E10 AND E11 IN MYOGLOBINS: ATTEMPTS TO SIMULATE THE O2 AND CO BINDING PROPERTIES OF APLYSIA MYOGLOBIN
Descriptor:MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Krzywda, S., Wilkinson, A.J.
Deposit date:1995-01-11
Release date:1995-04-20
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interactions among residues CD3, E7, E10, and E11 in myoglobins: attempts to simulate the ligand-binding properties of Aplysia myoglobin.
Biochemistry, 34, 1995
1MNK
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INTERACTIONS AMONG RESIDUES CD3, E7, E10 AND E11 IN MYOGLOBINS: ATTEMPTS TO SIMULATE THE O2 AND CO BINDING PROPERTIES OF APLYSIA MYOGLOBIN
Descriptor:MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Krzywda, S., Wilkinson, A.J.
Deposit date:1995-01-11
Release date:1995-04-20
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interactions among residues CD3, E7, E10, and E11 in myoglobins: attempts to simulate the ligand-binding properties of Aplysia myoglobin.
Biochemistry, 34, 1995
3ZUX
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CRYSTAL STRUCTURE OF A BACTERIAL HOMOLOGUE OF THE BILE ACID SODIUM SYMPORTER ASBT.
Descriptor:TRANSPORTER, SODIUM ION, MERCURY (II) ION, ...
Authors:Hu, N.-J., Iwata, S., Cameron, A.D., Drew, D.
Deposit date:2011-07-21
Release date:2011-10-12
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Bacterial Homologue of the Bile Acid Sodium Symporter Asbt.
Nature, 478, 2011
3ZUY
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CRYSTAL STRUCTURE OF A BACTERIAL HOMOLOGUE OF THE BILE ACID SODIUM SYMPORTER ASBT.
Descriptor:TRANSPORTER, SODIUM ION, TAUROCHOLIC ACID, ...
Authors:Hu, N.-J., Iwata, S., Cameron, A.D., Drew, D.
Deposit date:2011-07-21
Release date:2011-10-12
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Bacterial Homologue of the Bile Acid Sodium Symporter Asbt.
Nature, 478, 2011
1RK2
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E. COLI RIBOKINASE COMPLEXED WITH RIBOSE AND ADP, SOLVED IN SPACE GROUP P212121
Descriptor:RIBOKINASE, RIBOSE, TETRAFLUOROALUMINATE ION, ...
Authors:Sigrell, J.A., Cameron, A.D., Mowbray, S.L.
Deposit date:1999-05-20
Release date:1999-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Induced fit on sugar binding activates ribokinase.
J.Mol.Biol., 290, 1999
1BYL
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BLEOMYCIN RESISTANCE PROTEIN FROM STREPTOALLOTEICHUS HINDUSTANUS
Descriptor:PROTEIN (BLEOMYCIN RESISTANCE PROTEIN)
Authors:Dumas, P., Bergdoll, M., Cagnon, C., Masson, J.M.
Deposit date:1998-10-17
Release date:1999-10-21
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and site-directed mutagenesis of a bleomycin resistance protein and their significance for drug sequestering.
EMBO J., 13, 1994
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