Author results

1BRS
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PROTEIN-PROTEIN RECOGNITION: CRYSTAL STRUCTURAL ANALYSIS OF A BARNASE-BARSTAR COMPLEX AT 2.0-A RESOLUTION
Descriptor:BARNASE, BARSTAR
Authors:Buckle, A.M., Schreiber, G., Fersht, A.R.
Deposit date:1994-03-11
Release date:1994-06-22
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution.
Biochemistry, 33, 1994
1BRN
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SUBSITE BINDING IN AN RNASE: STRUCTURE OF A BARNASE-TETRANUCLEOTIDE COMPLEX AT 1.76 ANGSTROMS RESOLUTION
Descriptor:DNA (5'-D(*CP*GP*AP*C)-3'), PROTEIN (BARNASE (E.C.3.1.27.-))
Authors:Buckle, A.M., Fersht, A.R.
Deposit date:1993-11-17
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Subsite binding in an RNase: structure of a barnase-tetranucleotide complex at 1.76-A resolution.
Biochemistry, 33, 1994
1BSA
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CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor:BARNASE
Authors:Buckle, A.M., Henrick, K., Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BSB
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CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor:BARNASE
Authors:Buckle, A.M., Henrick, K., Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BSC
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CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor:BARNASE
Authors:Buckle, A.M., Henrick, K., Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BSD
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CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor:BARNASE
Authors:Buckle, A.M., Henrick, K., Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BSE
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CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor:BARNASE
Authors:Buckle, A.M., Henrick, K., Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1KID
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GROEL (HSP60 CLASS) FRAGMENT (APICAL DOMAIN) COMPRISING RESIDUES 191-376, MUTANT WITH ALA 262 REPLACED WITH LEU AND ILE 267 REPLACED WITH MET
Descriptor:GROEL (HSP60 CLASS)
Authors:Buckle, A.M., Fersht, A.R.
Deposit date:1996-12-13
Release date:1997-09-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A structural model for GroEL-polypeptide recognition.
Proc.Natl.Acad.Sci.USA, 94, 1997
1BNI
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BARNASE WILDTYPE STRUCTURE AT PH 6.0
Descriptor:BARNASE
Authors:Cameron, A., Henrick, K., Fersht, A.R., Dodson, G., Buckle, A.M.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BNJ
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BARNASE WILDTYPE STRUCTURE AT PH 9.0
Descriptor:BARNASE
Authors:Cameron, A., Henrick, K., Fersht, A.R., Dodson, G., Buckle, A.M.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1CIQ
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COMPLEX OF TWO FRAGMENTS OF CI2, RESIDUES 1-40 AND 41-64
Descriptor:CHYMOTRYPSIN INHIBITOR 2
Authors:Buckle, A.M., Fersht, A.R.
Deposit date:1995-10-02
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism
Structure Fold.Des., 1, 1996
1JON
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GROEL (HSP60 CLASS) FRAGMENT COMPRISING RESIDUES 191-345
Descriptor:GROEL, HSP60 CLASS
Authors:Buckle, A.M., Fersht, A.R.
Deposit date:1996-05-30
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Chaperone activity and structure of monomeric polypeptide binding domains of GroEL.
Proc.Natl.Acad.Sci.USA, 93, 1996
2DG3
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WILDTYPE FK506-BINDING PROTEIN COMPLEXED WITH RAPAMYCIN
Descriptor:FK506-binding protein 1A, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, GLYCEROL
Authors:Buckle, A.M.
Deposit date:2006-03-08
Release date:2006-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Energetic and structural analysis of the role of tryptophan 59 in FKBP12
Biochemistry, 42, 2003
2DG4
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FK506-BINDING PROTEIN MUTANT WF59 COMPLEXED WITH RAPAMYCIN
Descriptor:FK506-binding protein 1A, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, GLYCEROL
Authors:Buckle, A.M.
Deposit date:2006-03-08
Release date:2006-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Energetic and structural analysis of the role of tryptophan 59 in FKBP12
Biochemistry, 42, 2003
2GPZ
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TRANSTHYRETIN-LIKE PROTEIN FROM SALMONELLA DUBLIN
Descriptor:transthyretin-like protein, SULFATE ION
Authors:Buckle, A.M., Law, R.H., Whisstock, J.C.
Deposit date:2006-04-19
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Crystal Structure of the Transthyretin-like Protein from Salmonella dublin, a Prokaryote 5-Hydroxyisourate Hydrolase.
J.Mol.Biol., 359, 2006
2H4P
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CRYSTAL STRUCTURE OF WILDTYPE MENT IN THE CLEAVED CONFORMATION
Descriptor:Heterochromatin-associated protein MENT
Authors:Buckle, A.M., McGowan, S., Irving, J.A., Whisstock, J.C.
Deposit date:2006-05-24
Release date:2006-07-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
2OKJ
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THE X-RAY CRYSTAL STRUCTURE OF THE 67KDA ISOFORM OF GLUTAMIC ACID DECARBOXYLASE (GAD67)
Descriptor:Glutamate decarboxylase 1, GAMMA-AMINO-BUTANOIC ACID, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID
Authors:Buckle, A.M., Fenalti, G., Law, R.H.P., Whisstock, J.C.
Deposit date:2007-01-17
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
2OKK
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THE X-RAY CRYSTAL STRUCTURE OF THE 65KDA ISOFORM OF GLUTAMIC ACID DECARBOXYLASE (GAD65)
Descriptor:Glutamate decarboxylase 2, GAMMA-AMINO-BUTANOIC ACID, GLYCEROL
Authors:Buckle, A.M., Fenalti, G., Law, R.H.P., Whisstock, J.C.
Deposit date:2007-01-17
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
3FZZ
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STRUCTURE OF GRC
Descriptor:Granzyme C, SULFATE ION
Authors:Buckle, A.M., Kaiserman, D., Whisstock, J.C.
Deposit date:2009-01-27
Release date:2009-03-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of granzyme C reveals an unusual mechanism of protease autoinhibition
Proc.Natl.Acad.Sci.USA, 106, 2009
3G01
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STRUCTURE OF GRC MUTANT E192R/E193G
Descriptor:Granzyme C
Authors:Buckle, A.M., Kaiserman, D., Whisstock, J.C.
Deposit date:2009-01-27
Release date:2009-03-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of granzyme C reveals an unusual mechanism of protease autoinhibition
Proc.Natl.Acad.Sci.USA, 106, 2009
3H7O
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CRYSTAL STRUCTURE OF SCABIES MITE INACTIVATED PROTEASE PARALOGUE S-I1 (SMIPP-S-I1)
Descriptor:Group 3 allergen SMIPP-S Yv6023A04, SULFATE ION, GLYCEROL
Authors:Buckle, A.M.
Deposit date:2009-04-28
Release date:2009-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural mechanisms of inactivation in scabies mite serine protease paralogues.
J.Mol.Biol., 390, 2009
3H7T
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CRYSTAL STRUCTURE OF SCABIES MITE INACTIVATED PROTEASE PARALOGUE S-D1 (SMIPP-S-D1)
Descriptor:Group 3 allergen SMIPP-S YvT004A06, ZINC ION
Authors:Buckle, A.M.
Deposit date:2009-04-28
Release date:2009-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural mechanisms of inactivation in scabies mite serine protease paralogues.
J.Mol.Biol., 390, 2009
1B27
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STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
Descriptor:PROTEIN (BARNASE), PROTEIN (BARSTAR)
Authors:Vaughan, C.K., Buckle, A.M., Fersht, A.R.
Deposit date:1998-12-04
Release date:1998-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999
1B2S
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STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
Descriptor:PROTEIN (BARNASE), PROTEIN (BARSTAR), SULFATE ION
Authors:Vaughan, C.K., Buckle, A.M., Fersht, A.R.
Deposit date:1998-11-30
Release date:1998-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999
1B2U
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STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
Descriptor:PROTEIN (BARNASE), PROTEIN (BARSTAR)
Authors:Vaughan, C.K., Buckle, A.M., Fersht, A.R.
Deposit date:1998-12-01
Release date:1998-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999