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4R0X
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ALLOSTERIC COUPLING OF CONFORMATIONAL TRANSITIONS IN THE FK1 DOMAIN OF FKBP51 NEAR THE SITE OF STEROID RECEPTOR INTERACTION
Descriptor:Peptidyl-prolyl cis-trans isomerase FKBP5
Authors:LeMaster, D.M., Mustafi, S.M., Brecher, M., Zhang, J., Heroux, A., Li, H.M., Hernandez, G.
Deposit date:2014-08-02
Release date:2015-05-13
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins.
J.Biol.Chem., 290, 2015
5CUQ
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IDENTIFICATION AND CHARACTERIZATION OF NOVEL BROAD SPECTRUM INHIBITORS OF THE FLAVIVIRUS METHYLTRANSFERASE
Descriptor:Nonstructural protein NS5, N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA
Authors:Brecher, B., Chen, H., Li, Z., Banavali, N.K., Jones, S.A., Zhang, J., Kramer, L.D., Li, H.M.
Deposit date:2015-07-24
Release date:2016-02-03
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.696 Å)
Cite:Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase.
Acs Infect Dis., 1, 2015
4N19
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STRUCTURAL BASIS OF CONFORMATIONAL TRANSITIONS IN THE ACTIVE SITE AND 80 S LOOP IN THE FK506 BINDING PROTEIN FKBP12
Descriptor:Peptidyl-prolyl cis-trans isomerase FKBP1A, SULFATE ION
Authors:Mustafi, S.M., Brecher, M.B., Zhang, J., Li, H.M., Lemaster, D.M., Hernandez, G.
Deposit date:2013-10-03
Release date:2014-02-12
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural basis of conformational transitions in the active site and 80's loop in the FK506-binding protein FKBP12.
Biochem.J., 458, 2014