Author results

2CK3
  • Download 2ck3
  • View 2ck3
Molmil generated image of 2ck3
AZIDE INHIBITED BOVINE F1-ATPASE
Descriptor:ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL, ATP SYNTHASE SUBUNIT BETA, ...
Authors:Bowler, M.W., Montgomery, M.G., Leslie, A.G.W., Walker, J.E.
Deposit date:2006-04-10
Release date:2006-05-08
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:How Azide Inhibits ATP Hydrolysis by the F-Atpases.
Proc.Natl.Acad.Sci.USA, 103, 2006
2JDI
  • Download 2jdi
  • View 2jdi
Molmil generated image of 2jdi
GROUND STATE STRUCTURE OF F1-ATPASE FROM BOVINE HEART MITOCHONDRIA (BOVINE F1-ATPASE CRYSTALLISED IN THE ABSENCE OF AZIDE)
Descriptor:ATP SYNTHASE SUBUNIT ALPHA HEART ISOFORM, ATP SYNTHASE SUBUNIT BETA, ATP SYNTHASE GAMMA CHAIN, ...
Authors:Bowler, M.W., Montgomery, M.G., Leslie, A.G.W., Walker, J.E.
Deposit date:2007-01-09
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ground State Structure of F1-ATPase from Bovine Heart Mitochondria at 1.9 A Resolution
J.Biol.Chem., 282, 2007
2X13
  • Download 2x13
  • View 2x13
Molmil generated image of 2x13
THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE IN COMPLEX WITH ADP AND 3PHOSPHOGLYCERATE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, 3-PHOSPHOGLYCERIC ACID, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hownslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-12-21
Release date:2010-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The Structure of Human Phosphoglycerate Kinase in its Fully Active Conformation with Ground State Analogues
To be Published
2X14
  • Download 2x14
  • View 2x14
Molmil generated image of 2x14
THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE K219A MUTANT IN COMPLEX WITH AMP-PCP AND 3PG
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, 3-PHOSPHOGLYCERIC ACID, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hownslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-12-21
Release date:2010-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Structure of Human Phosphoglycerate Kinase in its Fully Active Conformation in Complex with Ground State Analogues
To be Published
2X15
  • Download 2x15
  • View 2x15
Molmil generated image of 2x15
THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE IN COMPLEX WITH ADP AND 1,3- BISPHOSPHOGLYCERATE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hounslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-12-21
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of Human Phosphoglycerate Kinase in its Fully Active Conformation in Complex with Ground State Analoges
To be Published
3ZOZ
  • Download 3zoz
  • View 3zoz
Molmil generated image of 3zoz
THE STRUCTURE OF HUMAN PHOSPHOGLYCERATE KINASE WITH BOUND BROMIDE, A STIMULATING ANION.
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, BROMIDE ION, ...
Authors:Bowler, M.W.
Deposit date:2013-02-26
Release date:2014-03-12
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Identification of the Activating Anion Binding Site in Human Phosphoglycerate Kinase
To be Published
4AXX
  • Download 4axx
  • View 4axx
Molmil generated image of 4axx
THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE IN COMPLEX WITH ADP 3-PHOSPHOGLYCERATE AND BERYLLIUM TRIFLUORIDE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Bowler, M.W.
Deposit date:2012-06-15
Release date:2013-06-26
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Catalytic Activity in the Transitions State Analogue Stabilised Conformation of a Phosphoryl Transfer Enzyme
To be Published
2WF5
  • Download 2wf5
  • View 2wf5
Molmil generated image of 2wf5
STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH GLUCOSE-6-PHOSPHATE AND TRIFLUOROMAGNESATE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, BETA-D-GLUCOSE-6-PHOSPHATE, MAGNESIUM ION, ...
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Hounslow, A.M., Cliff, M.J., Williams, N.H., Hollfelder, F., Gamblin, S., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2009-09-15
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.
Proc. Natl. Acad. Sci. U.S.A., 107, 2010
2WF6
  • Download 2wf6
  • View 2wf6
Molmil generated image of 2wf6
STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH GLUCOSE-6-PHOSPHATE AND ALUMINIUM TETRAFLUORIDE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, TETRAFLUOROALUMINATE ION, MAGNESIUM ION, ...
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2010-05-26
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.
Proc. Natl. Acad. Sci. U.S.A., 107, 2010
2WF7
  • Download 2wf7
  • View 2wf7
Molmil generated image of 2wf7
STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH GLUCOSE-6- PHOSPHONATE AND ALUMINIUM TETRAFLUORIDE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, TETRAFLUOROALUMINATE ION, MAGNESIUM ION, ...
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2010-05-19
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Alpha-Fluorophosphonates Reveal How a Phosphomutase Conserves Transition State Conformation Over Hexose Recognition in its Two-Step Reaction.
Proc.Natl.Acad.Sci.USA, 111, 2014
2WF8
  • Download 2wf8
  • View 2wf8
Molmil generated image of 2wf8
STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH GLUCOSE-6- PHOSPHATE, GLUCOSE-1-PHOSPHATE AND BERYLLIUM TRIFLUORIDE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2010-05-26
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Near attack conformers dominate beta-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
2WF9
  • Download 2wf9
  • View 2wf9
Molmil generated image of 2wf9
STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH GLUCOSE-6- PHOSPHATE, AND BERYLLIUM TRIFLUORIDE, CRYSTAL FORM 2
Descriptor:BETA-PHOSPHOGLUCOMUTASE, MAGNESIUM ION, ALPHA-D-GLUCOSE-6-PHOSPHATE, ...
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2010-05-26
Last modified:2012-05-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Near Attack Conformers Dominate Beta-Phosphoglucomutase Complexes Where Geometry and Charge Distribution Reflect Those of Substrate.
Proc.Natl.Acad.Sci.USA, 109, 2012
2WFA
  • Download 2wfa
  • View 2wfa
Molmil generated image of 2wfa
STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH BERYLLIUM TRIFLUORIDE, IN AN OPEN CONFORMATION.
Descriptor:BETA-PHOSPHOGLUCOMUTASE, MAGNESIUM ION, BERYLLIUM TRIFLUORIDE ION
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2010-05-26
Last modified:2012-05-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Near Attack Conformers Dominate Beta-Phosphoglucomutase Complexes Where Geometry and Charge Distribution Reflect Those of Substrate.
Proc.Natl.Acad.Sci.USA, 109, 2012
2WHE
  • Download 2whe
  • View 2whe
Molmil generated image of 2whe
STRUCTURE OF NATIVE BETA-PHOSPHOGLUCOMUTASE IN AN OPEN CONFORMATION WITHOUT BOUND LIGANDS.
Descriptor:BETA-PHOSPHOGLUCOMUTASE, MAGNESIUM ION
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-05-04
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Atomic Details of Near-Transition State Conformers for Enzyme Phosphoryl Transfer Revealed by Mgf-3 Rather Than by Phosphoranes.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WZB
  • Download 2wzb
  • View 2wzb
Molmil generated image of 2wzb
THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE IN COMPLEX WITH ADP, 3PG AND MAGNESIUM TRIFLUORIDE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hownslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-11-27
Release date:2010-04-14
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis.
J.Am.Chem.Soc., 132, 2010
2WZC
  • Download 2wzc
  • View 2wzc
Molmil generated image of 2wzc
THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE IN COMPLEX WITH ADP, 3PG AND ALUMINIUM TETRAFLUORIDE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hownslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-11-27
Release date:2010-04-14
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis.
J.Am.Chem.Soc., 132, 2010
2WZD
  • Download 2wzd
  • View 2wzd
Molmil generated image of 2wzd
THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE K219A MUTANT IN COMPLEX WITH ADP, 3PG AND ALUMINIUM TRIFLUORIDE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hownslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-11-27
Release date:2010-04-14
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis.
J.Am.Chem.Soc., 132, 2010
2Y3I
  • Download 2y3i
  • View 2y3i
Molmil generated image of 2y3i
THE STRUCTURE OF THE FULLY CLOSED CONFORMATION OF HUMAN PGK IN COMPLEX WITH L-ADP, 3PG AND THE TSA ALUMINIUM TETRAFLUORIDE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Bowler, M.W., Chaloin, L., Lionne, C.
Deposit date:2010-12-21
Release date:2011-04-27
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Interaction of Human 3-Phosphoglycerate Kinase with its Two Substrates: Is Substrate Antagonism a Kinetic Advantage?
J.Mol.Biol., 409, 2011
2YBE
  • Download 2ybe
  • View 2ybe
Molmil generated image of 2ybe
THE STRUCTURE OF THE FULLY CLOSED CONFORMATION OF HUMAN PGK IN COMPLEX WITH L-ADP, 3PG AND THE TSA ALUMINIUM TETRAFLUORIDE AT 2.0 A RESOLUTION
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Bowler, M.W., Chaloin, L., Lionne, C.
Deposit date:2011-03-07
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interaction of Human 3-Phosphoglycerate Kinase with its Two Substrates: Is Substrate Antagonism a Kinetic Advantage?
J.Mol.Biol., 409, 2011
3ZI4
  • Download 3zi4
  • View 3zi4
Molmil generated image of 3zi4
THE STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH GLUCOSE-6-PHOSPHATE AND SCANDIUM TETRAFLUORIDE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, MAGNESIUM ION, BETA-D-GLUCOSE-6-PHOSPHATE, ...
Authors:Pellegrini, E., Bowler, M.W.
Deposit date:2013-01-03
Release date:2014-01-15
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Metal Fluorides: Multi-Functional Tools for the Study of Phosphoryl Transfer Enzymes
To be Published
3ZI6
  • Download 3zi6
  • View 3zi6
Molmil generated image of 3zi6
STRUCTURE OF THERMOLYSIN SOLVED BY SAD FROM DATA COLLECTED BY DIRECT DATA COLLECTION (DDC) USING THE GROB ROBOT GONIOMETER
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:Bowler, M.W.
Deposit date:2013-01-04
Release date:2013-05-01
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recent Progress in Robot-Based Systems for Crystallography and Their Contribution to Drug Discovery.
Expert Opin.Drug Discov., 8, 2013
3ZI7
  • Download 3zi7
  • View 3zi7
Molmil generated image of 3zi7
STRUCTURE OF FAE SOLVED BY SAD FROM DATA COLLECTED BY DIRECT DATA COLLECTION (DDC) USING THE GROB ROBOT GONIOMETER
Descriptor:ENDO-1,4-BETA-XYLANASE Y, CADMIUM ION
Authors:Bowler, M.W.
Deposit date:2013-01-04
Release date:2013-05-01
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Recent Progress in Robot-Based Systems for Crystallography and Their Contribution to Drug Discovery.
Expert Opin.Drug Discov., 8, 2013
5FXL
  • Download 5fxl
  • View 5fxl
Molmil generated image of 5fxl
STRUCTURE OF TRYPSIN SOLVED BY MR FROM DATA COLLECTED BY DIRECT DATA COLLECTION (DDC) USING THE ESRF ROBODIFF GONIOMETER
Descriptor:CATIONIC TRYPSIN, CALCIUM ION, BENZAMIDINE, ...
Authors:Bowler, M.W., Nurizzo, D.
Deposit date:2016-03-02
Release date:2016-03-16
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Robodiff: Combining a Sample Changer and Goniometer for Highly Automated Macromolecular Crystallography Experiments.
Acta Crystallogr.,Sect.D, 72, 2016
5FXM
  • Download 5fxm
  • View 5fxm
Molmil generated image of 5fxm
STRUCTURE OF FAE SOLVED BY SAD FROM DATA COLLECTED BY DIRECT DATA COLLECTION (DDC) USING THE ESRF ROBODIFF GONIOMETER
Descriptor:ENDO-1,4-BETA-XYLANASE Y, CADMIUM ION
Authors:Bowler, M.W., Nurizzo, D.
Deposit date:2016-03-02
Release date:2016-03-16
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Robodiff: Combining a Sample Changer and Goniometer for Highly Automated Macromolecular Crystallography Experiments.
Acta Crystallogr.,Sect.D, 72, 2016
5FXN
  • Download 5fxn
  • View 5fxn
Molmil generated image of 5fxn
STRUCTURE OF THERMOLYSIN SOLVED BY SAD FROM DATA COLLECTED BY DIRECT DATA COLLECTION (DDC) USING THE ESRF ROBODIFF GONIOMETER
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:Bowler, M.W., Nurizzo, D.
Deposit date:2016-03-02
Release date:2016-03-16
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Robodiff: Combining a Sample Changer and Goniometer for Highly Automated Macromolecular Crystallography Experiments.
Acta Crystallogr.,Sect.D, 72, 2016
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2019 Protein Data Bank Japan