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5W3S
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF A TRPML3 ION CHANNEL
Descriptor:Mucolipin-3 isoform 1, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ...
Authors:Hirschi, M., Herzik, M.A., Wie, J., Suo, Y., Borschel, W.F., Ren, D., Lander, G.C., Lee, S.Y.
Deposit date:2017-06-08
Release date:2017-10-11
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.
Nature, 550, 2017
6BPQ
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STRUCTURE OF THE COLD- AND MENTHOL-SENSING ION CHANNEL TRPM8
Descriptor:Transient receptor potential cation channel subfamily M member 8
Authors:Yin, Y., Wu, M., Zubcevic, L., Borschel, W.F., Lander, G.C., Lee, S.-Y.
Deposit date:2017-11-25
Release date:2017-12-13
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the cold- and menthol-sensing ion channel TRPM8.
Science, 359, 2018
6D73
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CRYO-EM STRUCTURE OF THE ZEBRAFISH TRPM2 CHANNEL IN THE PRESENCE OF CA2+
Descriptor:Transient receptor potential cation channel, subfamily M, CALCIUM ION
Authors:Yin, Y., Wu, M., Borschel, W.F., Lander, G.C., Lee, S.-Y.
Deposit date:2018-04-23
Release date:2019-05-15
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Nat Commun, 10, 2019
6MHO
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STRUCTURE OF THE HUMAN TRPV3 CHANNEL IN THE APO CONFORMATION
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHS
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STRUCTURE OF THE HUMAN TRPV3 CHANNEL IN A PUTATIVE SENSITIZED CONFORMATION
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHV
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C4 SYMMETRY
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHW
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C2 SYMMETRY (1)
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHX
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C2 SYMMETRY (2)
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6OT2
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STRUCTURE OF THE TRPV3 K169A SENSITIZED MUTANT IN APO FORM AT 4.1 A RESOLUTION
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Borschel, W.F., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-05-02
Release date:2019-05-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Elife, 8, 2019
6OT5
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STRUCTURE OF THE TRPV3 K169A SENSITIZED MUTANT IN THE PRESENCE OF 2-APB AT 3.6 A RESOLUTION
Descriptor:Transient receptor potential cation channel subfamily V member 3,Transient receptor potential cation channel subfamily V member 3, 2-aminoethyl diphenylborinate
Authors:Zubcevic, L., Borschel, W.F., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-05-02
Release date:2019-05-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Elife, 8, 2019
6PKV
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CRYO-EM STRUCTURE OF THE ZEBRAFISH TRPM2 CHANNEL IN THE APO CONFORMATION, PROCESSED WITH C4 SYMMETRY
Descriptor:Transient receptor potential cation channel subfamily M member 2
Authors:Yin, Y., Wu, M., Hsu, A.L., Borschel, W.F., Borgnia, M.J., Lander, G.C., Lee, S.-Y.
Deposit date:2019-06-30
Release date:2019-08-28
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Nat Commun, 10, 2019
6PKW
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CRYO-EM STRUCTURE OF THE ZEBRAFISH TRPM2 CHANNEL IN THE APO CONFORMATION, PROCESSED WITH C2 SYMMETRY (PSEUDO C4 SYMMETRY)
Descriptor:Transient receptor potential cation channel subfamily M member 2
Authors:Yin, Y., Wu, M., Hsu, A.L., Borschel, W.F., Borgnia, M.J., Lander, G.C., Lee, S.-Y.
Deposit date:2019-06-30
Release date:2019-08-28
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Nat Commun, 10, 2019
6PKX
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CRYO-EM STRUCTURE OF THE ZEBRAFISH TRPM2 CHANNEL IN THE PRESENCE OF ADPR AND CA2+
Descriptor:Transient receptor potential cation channel subfamily M member 2, CALCIUM ION, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Yin, Y., Wu, M., Hsu, A.L., Borschel, W.F., Borgnia, M.J., Lander, G.C., Lee, S.-Y.
Deposit date:2019-06-30
Release date:2019-08-28
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Nat Commun, 10, 2019