6H2Y
| human Fab 1E6 bound to fHbp variant 3 from Neisseria meningitidis serogroup B | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Veggi, D, Bianchi, F, Cozzi, R, Malito, E, Bottomley, M.J. | Deposit date: | 2018-07-17 | Release date: | 2019-08-14 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6. Faseb J., 33, 2019
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8D47
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8D48
| sd1.040 Fab in complex with SARS-CoV-2 Spike 2P glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, sd1.040 Fab heavy chain, ... | Authors: | Abernathy, M.E, Barnes, C.O. | Deposit date: | 2022-06-01 | Release date: | 2023-01-25 | Last modified: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein. Sci Immunol, 8, 2023
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5UR8
| Human antibody fragment (Fab) to meningococcal Factor H binding protein | Descriptor: | human immunoglobulin gamma, heavy chain Fd fragment, kappa light chain | Authors: | Beernink, P.T. | Deposit date: | 2017-02-09 | Release date: | 2018-02-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.75500226 Å) | Cite: | Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp. Nat Commun, 9, 2018
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6XZW
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8BK2
| X-ray structure of meningococcal factor H binding protein variant 2 in complex with a specific and bactericidal human monoclonal antibody 1B1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ... | Authors: | Veggi, D, Bottomley, J.M. | Deposit date: | 2022-11-08 | Release date: | 2023-11-22 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Bactericidal human monoclonal antibody 1B1 shows specificity for meningococcal factor H binding protein variant 2 and displaces human factor H. Faseb Bioadv, 6, 2024
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5O14
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7LSE
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7LSF
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7LSG
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