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6H2Y
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BU of 6h2y by Molmil
human Fab 1E6 bound to fHbp variant 3 from Neisseria meningitidis serogroup B
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Veggi, D, Bianchi, F, Cozzi, R, Malito, E, Bottomley, M.J.
Deposit date:2018-07-17
Release date:2019-08-14
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6.
Faseb J., 33, 2019
8D47
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BU of 8d47 by Molmil
fp.006 Fab in complex with SARS-CoV-2 Fusion Peptide
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ...
Authors:Abernathy, M.E, Barnes, C.O.
Deposit date:2022-06-01
Release date:2022-12-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein.
Sci Immunol, 8, 2023
8D48
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BU of 8d48 by Molmil
sd1.040 Fab in complex with SARS-CoV-2 Spike 2P glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, sd1.040 Fab heavy chain, ...
Authors:Abernathy, M.E, Barnes, C.O.
Deposit date:2022-06-01
Release date:2023-01-25
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein.
Sci Immunol, 8, 2023
5UR8
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BU of 5ur8 by Molmil
Human antibody fragment (Fab) to meningococcal Factor H binding protein
Descriptor: human immunoglobulin gamma, heavy chain Fd fragment, kappa light chain
Authors:Beernink, P.T.
Deposit date:2017-02-09
Release date:2018-02-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75500226 Å)
Cite:Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp.
Nat Commun, 9, 2018
6XZW
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BU of 6xzw by Molmil
Crystal structure of the meningococcal vaccine antigen fHbp in complex with a cross-reactive human Fab.
Descriptor: 1,2-ETHANEDIOL, Fab 4B3 (heavy chain), Fab 4B3 (light chain), ...
Authors:Veggi, D, Cozzi, R.
Deposit date:2020-02-05
Release date:2020-10-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp.
Plos Pathog., 16, 2020
8BK2
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BU of 8bk2 by Molmil
X-ray structure of meningococcal factor H binding protein variant 2 in complex with a specific and bactericidal human monoclonal antibody 1B1
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
Authors:Veggi, D, Bottomley, J.M.
Deposit date:2022-11-08
Release date:2023-11-22
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Bactericidal human monoclonal antibody 1B1 shows specificity for meningococcal factor H binding protein variant 2 and displaces human factor H.
Faseb Bioadv, 6, 2024
5O14
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BU of 5o14 by Molmil
Co-crystal structure of a cross-reactive bactericidal human antibody targeting meningococcal vaccine antigen factor H binding protein
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Fab 1A12 Heavy Chain, ...
Authors:Lopez-Sagaseta, J.
Deposit date:2017-05-18
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp.
Nat Commun, 9, 2018
7LSE
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BU of 7lse by Molmil
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Far Eastern Subtype)
Descriptor: Envelope protein E, GLYCEROL, T025 Fab Heavy Chain, ...
Authors:Keeffe, J.R, Bjorkman, P.J.
Deposit date:2021-02-18
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
J.Exp.Med., 218, 2021
7LSF
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BU of 7lsf by Molmil
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Western Subtype)
Descriptor: Envelope protein E, GLYCEROL, SODIUM ION, ...
Authors:Keeffe, J.R, Bjorkman, P.J.
Deposit date:2021-02-18
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
J.Exp.Med., 218, 2021
7LSG
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BU of 7lsg by Molmil
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Siberian Subtype)
Descriptor: Core protein, T025 Fab Heavy Chain, T025 Fab Light Chain
Authors:Keeffe, J.R, Bjorkman, P.J.
Deposit date:2021-02-18
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
J.Exp.Med., 218, 2021

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