7ZDQ
| Cryo-EM structure of Human ACE2 bound to a high-affinity SARS CoV-2 mutant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Bate, N, Savva, C.G, Moody, P.C.E, Brown, E.A, Schwabe, W.R, Brindle, N.P.J, Ball, J.K, Sale, J.E. | Deposit date: | 2022-03-29 | Release date: | 2022-05-18 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding. Plos Pathog., 18, 2022
|
|
2KMA
| NMR structure of the F0F1 double domain (residues 1-202) of the talin ferm domain | Descriptor: | Talin 1 | Authors: | Goult, B.T, Elliott, P.R, Bate, N, Roberts, G.C, Critchley, D.R, Barsukov, I.L. | Deposit date: | 2009-07-25 | Release date: | 2010-03-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. Embo J., 2010
|
|
2KVP
| Solution Structure of the R10 Domain of Talin | Descriptor: | Talin-1 | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R, Barsukov, I.L, Roberts, G.C. | Deposit date: | 2010-03-24 | Release date: | 2010-05-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site. Febs Lett., 584, 2010
|
|
2L7N
| Solution Structure of the R5 Domain of Talin | Descriptor: | Talin-1 | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Barsukov, I.L, Roberts, G.C.K, Critchley, D.R. | Deposit date: | 2010-12-14 | Release date: | 2011-12-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover. J.Biol.Chem., 288, 2013
|
|
1Y19
| Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions | Descriptor: | Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1 | Authors: | de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C. | Deposit date: | 2004-11-17 | Release date: | 2005-01-04 | Last modified: | 2016-11-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions J.Biol.Chem., 280, 2005
|
|
2QDQ
| Crystal structure of the talin dimerisation domain | Descriptor: | Talin-1 | Authors: | Gingras, A.R, Putz, N.S.M, Bate, N, Barsukov, I.L, Critchley, D.R.C. | Deposit date: | 2007-06-21 | Release date: | 2008-01-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of the C-terminal actin-binding domain of talin. Embo J., 27, 2008
|
|
3ZDL
| Vinculin head (1-258) in complex with a RIAM fragment | Descriptor: | AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN, VINCULIN | Authors: | Zacharchenko, T, Elliott, P.R, Goult, B.T, Bate, N, Critchely, D.R, Barsukov, I.L. | Deposit date: | 2012-11-28 | Release date: | 2013-02-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Riam and Vinculin Binding to Talin are Mutually Exclusive and Regulate Adhesion Assembly and Turnover. J.Biol.Chem., 288, 2013
|
|
2X0C
| Crystal Structure of the R7R8 domains of Talin | Descriptor: | TALIN-1 | Authors: | Gingras, A.R, Goult, B.T, Bate, N, Barsukov, I.L, Emsley, J, Critchely, D.R. | Deposit date: | 2009-12-08 | Release date: | 2010-07-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Central Region of Talin Has a Unique Fold that Binds Vinculin and Actin. J.Biol.Chem., 285, 2010
|
|
5OEO
| Solution structure of the complex of TRPV5(655-725) with a Calmodulin E32Q/E68Q double mutant | Descriptor: | CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 5 | Authors: | Vuister, G.W, Bokhovchuk, F.M, Bate, N, Kovalevskaya, N, Goult, B.T, Spronk, C.A.E.M. | Deposit date: | 2017-07-09 | Release date: | 2018-04-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Structural Basis of Calcium-Dependent Inactivation of the Transient Receptor Potential Vanilloid 5 Channel. Biochemistry, 57, 2018
|
|
2JSW
| Solution Structure of the R13 Domain of Talin | Descriptor: | Talin-1 | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R.C, Barsukov, I.L. | Deposit date: | 2007-07-17 | Release date: | 2008-01-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The structure of the C-terminal actin-binding domain of talin. Embo J., 27, 2007
|
|
2L10
| Solution Structure of the R6 Domain of Talin | Descriptor: | Talin-1 | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Roberts, G.C.K, Barsukov, I.L, Critchley, D.R. | Deposit date: | 2010-07-22 | Release date: | 2011-08-31 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover. J.Biol.Chem., 288, 2013
|
|
2LQG
| Solution Structure of the R4 domain of talin | Descriptor: | Talin-1 | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Roberts, G.C.K, Barsukov, I.L, Critchley, D.R. | Deposit date: | 2012-03-06 | Release date: | 2013-02-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover. J.Biol.Chem., 288, 2013
|
|
2L7A
| Solution Structure of the R3 Domain of Talin | Descriptor: | Talin-1 | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Roberts, G.C.K, Barsukov, I.L, Critchley, D.R. | Deposit date: | 2010-12-06 | Release date: | 2011-12-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover. J.Biol.Chem., 288, 2013
|
|
2KBB
| Solution Structure of the R9 Domain of Talin | Descriptor: | Talin-1 | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R, Barsukov, I.L. | Deposit date: | 2008-11-24 | Release date: | 2009-03-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of an interdomain complex that regulates talin activity. J.Biol.Chem., 284, 2009
|
|
2KGX
| HADDOCK structure of the talin F3 domain in complex with talin 1655-1822 | Descriptor: | MKIAA1027 protein, Talin-1 | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R, Barsukov, I.L. | Deposit date: | 2009-03-23 | Release date: | 2009-03-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of an interdomain complex that regulates talin activity. J.Biol.Chem., 284, 2009
|
|
2KMC
| Solution Structure of the N-terminal domain of kindlin-1 | Descriptor: | Fermitin family homolog 1 | Authors: | Goult, B.T, Bate, N, Roberts, G.C, Barsukov, I.L, Critchley, D.R. | Deposit date: | 2009-07-27 | Release date: | 2009-10-06 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The Structure of the N-Terminus of Kindlin-1: A Domain Important for alphaIIbbeta3 Integrin Activation J.Mol.Biol., 394, 2009
|
|
3IVF
| Crystal structure of the talin head FERM domain | Descriptor: | Talin-1 | Authors: | Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | Deposit date: | 2009-09-01 | Release date: | 2010-08-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | The Structure of the talin head reveals a novel extended conformation of the FERM domain Structure, 18, 2010
|
|
3G9W
| Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ... | Authors: | Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D. | Deposit date: | 2009-02-15 | Release date: | 2009-10-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.165 Å) | Cite: | The structure of an integrin/talin complex reveals the basis of inside-out signal transduction Embo J., 28, 2009
|
|
2KC1
| NMR structure of the F0 domain (residues 0-85) of the talin ferm domain | Descriptor: | MKIAA1027 protein | Authors: | Goult, B.T, Elliott, P.R, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | Deposit date: | 2008-12-13 | Release date: | 2010-01-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. Embo J., 29, 2010
|
|
1T01
| Vinculin complexed with the VBS1 helix from talin | Descriptor: | Talin 1, unnamed protein product | Authors: | Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J. | Deposit date: | 2004-04-07 | Release date: | 2004-08-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle Embo J., 23, 2004
|
|
1SJ7
| Crystal Structure of Talin Rod 482-655 | Descriptor: | PLATINUM (II) ION, Talin 1 | Authors: | Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J. | Deposit date: | 2004-03-03 | Release date: | 2004-08-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle EMBO J., 23, 2004
|
|
1SJ8
| Solution Structure of the R1R2 Domains of Talin | Descriptor: | Talin 1 | Authors: | Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J. | Deposit date: | 2004-03-03 | Release date: | 2004-08-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle EMBO J., 23, 2004
|
|
3DYJ
| |
2KC2
| NMR structure of the F1 domain (residues 86-202) of the talin | Descriptor: | Talin-1 | Authors: | Goult, B.T, Elliott, P.R, Roberts, G.C.K, Critchely, D.R, Barsukov, I.L. | Deposit date: | 2008-12-13 | Release date: | 2010-01-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. Embo J., 29, 2010
|
|