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2X0V
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STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE
Descriptor:CELLULAR TUMOR ANTIGEN P53, ZINC ION, 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE
Authors:Basse, N., Kaar, J.L., Joerger, A.C., Fersht, A.R.
Deposit date:2009-12-17
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant.
Chem.Biol., 17, 2010
2X0U
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STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO A 2-AMINO SUBSTITUTED BENZOTHIAZOLE SCAFFOLD
Descriptor:CELLULAR TUMOR ANTIGEN P53, ZINC ION, 6,7-DIHYDRO[1,4]DIOXINO[2,3-F][1,3]BENZOTHIAZOL-2-AMINE
Authors:Joerger, A.C., Kaar, J.L., Basse, N., Fersht, A.R.
Deposit date:2009-12-17
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant.
Chem.Biol., 17, 2010
2X0W
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STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 5,6-DIMETHOXY- 2-METHYLBENZOTHIAZOLE
Descriptor:CELLULAR TUMOR ANTIGEN P53, ZINC ION, 5,6-DIMETHOXY-2-METHYL-1,3-BENZOTHIAZOLE
Authors:Kaar, J.L., Basse, N., Joerger, A.C., Fersht, A.R.
Deposit date:2009-12-17
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant.
Chem.Biol., 17, 2010
3NZJ
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CRYSTAL STRUCTURE OF YEAST 20S PROTEASOME IN COMPLEX WITH LIGAND 2A
Descriptor:Proteasome component Y7, Proteasome component Y13, Proteasome component PRE6, ...
Authors:Groll, M., Gallastegui, N., Marechal, X., Le Ravalec, V., Basse, N., Richy, N., Genin, E., Huber, R., Moroder, M., Vidal, V., Reboud-Ravaux, M.
Deposit date:2010-07-16
Release date:2011-02-16
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A.
Chemmedchem, 5, 2010
3NZW
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CRYSTAL STRUCTURE OF THE YEAST 20S PROTEASOME IN COMPLEX WITH 2B
Descriptor:Proteasome component Y7, Proteasome component Y13, Proteasome component PRE6, ...
Authors:Groll, M., Gallastegui, N., Marechal, X., Le Ravalec, V., Basse, N., Richy, N., Genin, E., Huber, R., Moroder, M., Vidal, V., Reboud-Ravaux, M.
Deposit date:2010-07-17
Release date:2011-02-16
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A.
Chemmedchem, 5, 2010
3NZX
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CRYSTAL STRUCTURE OF THE YEAST 20S PROTEASOME IN COMPLEX WITH LIGAND 2C
Descriptor:Proteasome component Y7, Proteasome component Y13, Proteasome component PRE6, ...
Authors:Groll, M., Gallastegui, N., Marechal, X., Le Ravalec, V., Basse, N., Richy, N., Genin, E., Huber, R., Moroder, M., Vidal, V., Reboud-Ravaux, M.
Deposit date:2010-07-17
Release date:2011-02-16
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A.
Chemmedchem, 5, 2010
2L9N
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STRUCTURE OF THE HUMAN SHWACHMAN-BODIAN-DIAMOND SYNDROME (SBDS) PROTEIN
Descriptor:Ribosome maturation protein SBDS
Authors:Hilcenko, C., Freund, S.M.V., Warren, A.J.
Deposit date:2011-02-21
Release date:2011-05-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome.
Genes Dev., 25, 2011
6C97
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CRYSTAL STRUCTURE OF FCRN AT PH3
Descriptor:IgG receptor FcRn large subunit p51, Beta-2-microglobulin, GLYCEROL
Authors:Fox III, D., Fairman, J.W.
Deposit date:2018-01-25
Release date:2018-05-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16, 2018
6C98
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CRYSTAL STRUCTURE OF FCRN BOUND TO UCB-84
Descriptor:IgG receptor FcRn large subunit p51, Beta-2-microglobulin, CYSTEINE, ...
Authors:Fox III, D., Lukacs, C.M.
Deposit date:2018-01-25
Release date:2018-05-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16, 2018
6C99
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CRYSTAL STRUCTURE OF FCRN BOUND TO UCB-303
Descriptor:IgG receptor FcRn large subunit p51, Beta-2-microglobulin, methyl 7-(3,5-difluorophenyl)-5-(pyridin-3-yl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate, ...
Authors:Fox III, D., Abendroth, J., Porter, J., Deboves, H.
Deposit date:2018-01-25
Release date:2018-05-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16, 2018