Author results

4RQR
  • Download 4rqr
  • View 4rqr
Molmil generated image of 4rqr
CRYSTAL STRUCTURE OF HUMAN GLUTAREDOXIN WITH MESNA
Descriptor:Glutaredoxin-1, 1-THIOETHANESULFONIC ACID
Authors:Badger, J., Sridhar, V., Logan, C., Hausheer, F.H., Nienaber, V.L.
Deposit date:2014-11-04
Release date:2015-04-01
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
Molecules, 20, 2015
3PMO
  • Download 3pmo
  • View 3pmo
Molmil generated image of 3pmo
THE STRUCTURE OF LPXD FROM PSEUDOMONAS AERUGINOSA AT 1.3 A RESOLUTION
Descriptor:UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, 1,2-ETHANEDIOL, CHLORIDE ION
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2010-11-17
Release date:2011-07-27
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The structure of LpxD from Pseudomonas aeruginosa at 1.3 A resolution.
Acta Crystallogr.,Sect.F, 67, 2011
1VH5
  • Download 1vh5
  • View 1vh5
Molmil generated image of 1vh5
CRYSTAL STRUCTURE OF A PUTATIVE THIOESTERASE
Descriptor:Hypothetical protein ydiI
Authors:Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
1VHU
  • Download 1vhu
  • View 1vhu
Molmil generated image of 1vhu
CRYSTAL STRUCTURE OF A PUTATIVE PHOSPHOESTERASE
Descriptor:Hypothetical protein AF1521, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Structural GenomiX
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
1VIM
  • Download 1vim
  • View 1vim
Molmil generated image of 1vim
CRYSTAL STRUCTURE OF AN HYPOTHETICAL PROTEIN
Descriptor:Hypothetical protein AF1796, FORMIC ACID
Authors:Structural GenomiX
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
4E6U
  • Download 4e6u
  • View 4e6u
Molmil generated image of 4e6u
STRUCTURE OF LPXA FROM ACINETOBACTER BAUMANNII AT 1.4A RESOLUTION (P63 FORM)
Descriptor:Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, SULFATE ION, 1,2-ETHANEDIOL
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2012-03-16
Release date:2012-12-12
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 68, 2012
4LM4
  • Download 4lm4
  • View 4lm4
Molmil generated image of 4lm4
CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT902
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, quinazolin-4(1H)-one, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-10
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LM3
  • Download 4lm3
  • View 4lm3
Molmil generated image of 4lm3
CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT464
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethanone, NICKEL (II) ION, ...
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
1VHF
  • Download 1vhf
  • View 1vhf
Molmil generated image of 1vhf
CRYSTAL STRUCTURE OF PERIPLASMIC DIVALENT CATION TOLERANCE PROTEIN
Descriptor:periplasmic divalent cation tolerance protein
Authors:Structural GenomiX
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
1VHW
  • Download 1vhw
  • View 1vhw
Molmil generated image of 1vhw
CRYSTAL STRUCTURE OF PURINE NUCLEOSIDE PHOSPHORYLASE WITH ADENOSINE
Descriptor:purine nucleoside phosphorylase, ADENOSINE
Authors:Structural GenomiX
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
4LLK
  • Download 4llk
  • View 4llk
Molmil generated image of 4llk
CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT217
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 2-methylquinazolin-4(3H)-one, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LM2
  • Download 4lm2
  • View 4lm2
Molmil generated image of 4lm2
CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT462
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 2,3-dihydro-1,4-benzodioxin-6-ylmethanol, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LLJ
  • Download 4llj
  • View 4llj
Molmil generated image of 4llj
CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT214
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 2H-isoindole-1,3-diamine, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
1VIA
  • Download 1via
  • View 1via
Molmil generated image of 1via
CRYSTAL STRUCTURE OF SHIKIMATE KINASE
Descriptor:shikimate kinase, SULFATE ION
Authors:Structural GenomiX
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
1XBB
  • Download 1xbb
  • View 1xbb
Molmil generated image of 1xbb
CRYSTAL STRUCTURE OF THE SYK TYROSINE KINASE DOMAIN WITH GLEEVEC
Descriptor:Tyrosine-protein kinase SYK, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
Authors:Nienaber, V.L., Atwell, S., Adams, J.M., Badger, J., Buchanan, M.D., Feil, I.K., Froning, K.J., Gao, X., Hendle, J., Keegan, K., Leon, B.C., Muller-Deickmann, H.J., Noland, B.W., Post, K., Rajashankar, K.R., Ramos, A., Russell, M., Burley, S.K., Buchanan, S.G.
Deposit date:2004-08-30
Release date:2004-11-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:A Novel Mode of Gleevec Binding Is Revealed by the Structure of Spleen Tyrosine Kinase
J.Biol.Chem., 279, 2004
4MRZ
  • Download 4mrz
  • View 4mrz
Molmil generated image of 4mrz
CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT0429 (4-METHYL-3-NITROPYRIDIN-2-AMINE)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 4-methyl-3-nitropyridin-2-amine, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-09-17
Release date:2014-05-14
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
J Biomol Screen, 19, 2014
1VHN
  • Download 1vhn
  • View 1vhn
Molmil generated image of 1vhn
CRYSTAL STRUCTURE OF A PUTATIVE FLAVIN OXIDOREDUCTASE WITH FLAVIN
Descriptor:putative flavin oxidoreductase, SULFATE ION, FLAVIN MONONUCLEOTIDE
Authors:Structural GenomiX
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:The 1.59 A resolution crystal structure of TM0096, a flavin mononucleotide binding protein from Thermotoga maritima.
Proteins, 55, 2004
1VHT
  • Download 1vht
  • View 1vht
Molmil generated image of 1vht
CRYSTAL STRUCTURE OF DEPHOSPHO-COA KINASE WITH BIS(ADENOSINE)-5'-TRIPHOSPHATE
Descriptor:Dephospho-CoA kinase, ACETATE ION, BIS(ADENOSINE)-5'-TRIPHOSPHATE
Authors:Structural GenomiX
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
1VIO
  • Download 1vio
  • View 1vio
Molmil generated image of 1vio
CRYSTAL STRUCTURE OF PSEUDOURIDYLATE SYNTHASE
Descriptor:Ribosomal small subunit pseudouridine synthase A, 1,4-BUTANEDIOL
Authors:Structural GenomiX
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structure of the pseudouridine synthase RsuA from Haemophilus influenzae.
Acta Crystallogr.,Sect.F, 61, 2005
1VHD
  • Download 1vhd
  • View 1vhd
Molmil generated image of 1vhd
CRYSTAL STRUCTURE OF AN IRON CONTAINING ALCOHOL DEHYDROGENASE
Descriptor:alcohol dehydrogenase, iron-containing, CACODYLATE ION, ...
Authors:Structural GenomiX
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
4LM1
  • Download 4lm1
  • View 4lm1
Molmil generated image of 4lm1
CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT450
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 5-nitroquinoline, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-09
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4LKQ
  • Download 4lkq
  • View 4lkq
Molmil generated image of 4lkq
CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT017
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 4-amino-1,7-dihydro-6H-pyrazolo[3,4-d]pyrimidine-6-thione, NICKEL (II) ION
Authors:Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-07-08
Release date:2014-02-26
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
4MSA
  • Download 4msa
  • View 4msa
Molmil generated image of 4msa
CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT0449 (5-NITRO-1H-BENZIMIDAZOLE)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 5-nitro-1H-benzimidazole, NICKEL (II) ION
Authors:Sridar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
Deposit date:2013-09-18
Release date:2014-05-14
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
J Biomol Screen, 19, 2014
1VJE
  • Download 1vje
  • View 1vje
Molmil generated image of 1vje
CRYSTAL STRUCTURE OF A AUTOINDUCER-2 SYNTHESIS PROTEIN WITH BOUND SELENOMETHIONINE
Descriptor:Autoinducer-2 production protein LuxS, ZINC ION, SELENOMETHIONINE
Authors:Structural GenomiX
Deposit date:2004-02-03
Release date:2004-02-10
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:A Structural Genomics Approach to the Study of Quorum Sensing: Crystal Structures of Three LuxS Orthologs
Structure, 9, 2001
1VHL
  • Download 1vhl
  • View 1vhl
Molmil generated image of 1vhl
CRYSTAL STRUCTURE OF DEPHOSPHO-COA KINASE WITH ADENOSINE-5'-DIPHOSPHATE
Descriptor:Dephospho-CoA kinase, ADENOSINE-5'-DIPHOSPHATE, ACETATE ION
Authors:Structural GenomiX
Deposit date:2003-12-01
Release date:2003-12-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005