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1R08
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J., Smith, T.J., Rossmann, M.G.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
1RMU
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THREE-DIMENSIONAL STRUCTURES OF DRUG-RESISTANT MUTANTS OF HUMAN RHINOVIRUS 14
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J., Krishnaswamy, S., Kremer, M.J., Oliveira, M.A., Rossmann, M.G., Heinz, B.A., Rueckert, R.R., Dutko, F.J., Mckinlay, M.A.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three-dimensional structures of drug-resistant mutants of human rhinovirus 14.
J.Mol.Biol., 207, 1989
2R04
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J., Smith, T.J., Rossmann, M.G.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2R06
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J., Smith, T.J., Rossmann, M.G.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2R07
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J., Smith, T.J., Rossmann, M.G.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2RM2
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J., Smith, T.J., Rossmann, M.G.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2RMU
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THREE-DIMENSIONAL STRUCTURES OF DRUG-RESISTANT MUTANTS OF HUMAN RHINOVIRUS 14
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J., Krishnaswamy, S., Kremer, M.J., Oliveira, M.A., Rossmann, M.G., Heinz, B.A., Rueckert, R.R., Dutko, F.J., Mckinlay, M.A.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three-dimensional structures of drug-resistant mutants of human rhinovirus 14.
J.Mol.Biol., 207, 1989
2RR1
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J., Smith, T.J., Rossmann, M.G.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2RS1
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J., Smith, T.J., Rossmann, M.G.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2RS3
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J., Smith, T.J., Rossmann, M.G.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2RS5
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J., Smith, T.J., Rossmann, M.G.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
3PMO
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THE STRUCTURE OF LPXD FROM PSEUDOMONAS AERUGINOSA AT 1.3 A RESOLUTION
Descriptor:UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, 1,2-ETHANEDIOL, CHLORIDE ION
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2010-11-17
Release date:2011-07-27
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The structure of LpxD from Pseudomonas aeruginosa at 1.3 A resolution.
Acta Crystallogr.,Sect.F, 67, 2011
4E6T
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STRUCTURE OF LPXA FROM ACINETOBACTER BAUMANNII AT 1.8A RESOLUTION (P212121 FORM)
Descriptor:Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, CITRATE ANION
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2012-03-15
Release date:2012-12-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 68, 2012
4E6U
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STRUCTURE OF LPXA FROM ACINETOBACTER BAUMANNII AT 1.4A RESOLUTION (P63 FORM)
Descriptor:Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, SULFATE ION, 1,2-ETHANEDIOL
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2012-03-16
Release date:2012-12-12
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 68, 2012
4E75
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STRUCTURE OF LPXD FROM ACINETOBACTER BAUMANNII AT 2.85A RESOLUTION (P21 FORM)
Descriptor:UDP-3-O-acylglucosamine N-acyltransferase
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2012-03-16
Release date:2013-01-16
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 69, 2013
4E79
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STRUCTURE OF LPXD FROM ACINETOBACTER BAUMANNII AT 2.66A RESOLUTION (P4322 FORM)
Descriptor:UDP-3-O-acylglucosamine N-acyltransferase
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2012-03-16
Release date:2013-01-16
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 69, 2013
9INS
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MONOVALENT CATION BINDING IN CUBIC INSULIN CRYSTALS
Descriptor:INSULIN (CHAIN A), INSULIN (CHAIN B)
Authors:Badger, J., Dodson, G.G.
Deposit date:1991-10-23
Release date:1991-11-07
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Monovalent cation binding to cubic insulin crystals
Biophys.J., 61, 1992
1XBC
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CRYSTAL STRUCTURE OF THE SYK TYROSINE KINASE DOMAIN WITH STAUROSPORIN
Descriptor:Tyrosine-protein kinase SYK, STAUROSPORINE
Authors:Badger, J., Atwell, S., Adams, J.M., Buchanan, M.D., Feil, I.K., Froning, K.J., Gao, X., Hendle, J., Keegan, K., Leon, B.C., Muller-Deickmann, H.J., Nienaber, V.L., Noland, B.W., Post, K., Rajashankar, K.R., Ramos, A., Russell, M., Burley, S.K., Buchanan, S.G.
Deposit date:2004-08-30
Release date:2004-11-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase
J.Biol.Chem., 279, 2004
3TVX
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THE STRUCTURE OF PDE4A WITH PENTOXIFYLLINE AT 2.84A RESOLUTION
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4A, ZINC ION, MAGNESIUM ION, ...
Authors:Badger, J., Sridhar, V.
Deposit date:2011-09-20
Release date:2012-01-25
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Fragment-Based Screening for Inhibitors of PDE4A Using Enthalpy Arrays and X-ray Crystallography.
J Biomol Screen, 17, 2012
4RQR
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CRYSTAL STRUCTURE OF HUMAN GLUTAREDOXIN WITH MESNA
Descriptor:Glutaredoxin-1, 1-THIOETHANESULFONIC ACID
Authors:Badger, J., Sridhar, V., Logan, C., Hausheer, F.H., Nienaber, V.L.
Deposit date:2014-11-04
Release date:2015-04-01
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
Molecules, 20, 2015
4RQX
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CRYSTAL STRUCTURE OF HUMAN PEROXIREDOXIN 4(THIOREDOXIN PEROXIDASE) WITH MESNA
Descriptor:Peroxiredoxin-4, 1-THIOETHANESULFONIC ACID
Authors:Badger, J., Sridhar, V., Logan, C., Hausheer, F.H., Nienaber, V.L.
Deposit date:2014-11-05
Release date:2015-04-01
Method:X-RAY DIFFRACTION (2.256 Å)
Cite:Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
Molecules, 20, 2015
4TT7
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CRYSTAL STRUCTURE OF HUMAN ALK WITH A COVALENT MODIFICATION
Descriptor:ALK tyrosine kinase receptor, 1-THIOETHANESULFONIC ACID, 1,2-ETHANEDIOL
Authors:Badger, J., Sridhar, V., Chie-Leon, B., Nienaber, V.L., Hausheer, F.H.
Deposit date:2014-06-19
Release date:2015-02-11
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787.
Onco Targets Ther, 8, 2015
1APH
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CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11
Descriptor:INSULIN A CHAIN (PH 7), INSULIN B CHAIN (PH 7), 1,2-DICHLOROETHANE
Authors:Gursky, O., Badger, J., Li, Y., Caspar, D.L.D.
Deposit date:1992-10-30
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys.J., 63, 1992
1BPH
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CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11
Descriptor:INSULIN A CHAIN (PH 9), INSULIN B CHAIN (PH 9), SODIUM ION, ...
Authors:Gursky, O., Badger, J., Li, Y., Caspar, D.L.D.
Deposit date:1992-10-30
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys.J., 63, 1992
1CPH
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CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11
Descriptor:INSULIN (PH 10), SODIUM ION, 1,2-DICHLOROETHANE
Authors:Gursky, O., Badger, J., Li, Y., Caspar, D.L.D.
Deposit date:1992-10-30
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys.J., 63, 1992