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2PX2
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CRYSTAL STRUCTURE OF THE MURRAY VALLEY ENCEPHALITIS VIRUS NS5 2'-O METHYLTRANSFERASE DOMAIN IN COMPLEX WITH SAH (MONOCLINIC FORM 1)
Descriptor:Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Assenberg, R., Ren, J., Verma, A., Walter, T.S., Alderton, D., Hurrelbrink, R.J., Fuller, S.D., Owens, R.J., Stuart, D.I., Grimes, J.M., Oxford Protein Production Facility (OPPF)
Deposit date:2007-05-14
Release date:2007-05-29
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2PX4
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CRYSTAL STRUCTURE OF THE MURRAY VALLEY ENCEPHALITIS VIRUS NS5 2'-O METHYLTRANSFERASE DOMAIN IN COMPLEX WITH SAH (MONOCLINIC FORM 2)
Descriptor:Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], CHLORIDE ION, SULFATE ION, ...
Authors:Assenberg, R., Ren, J., Verma, A., Walter, T.S., Alderton, D., Hurrelbrink, R.J., Fuller, S.D., Owens, R.J., Stuart, D.I., Grimes, J.M., Oxford Protein Production Facility (OPPF)
Deposit date:2007-05-14
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2PX5
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CRYSTAL STRUCTURE OF THE MURRAY VALLEY ENCEPHALITIS VIRUS NS5 2'-O METHYLTRANSFERASE DOMAIN IN COMPLEX WITH SAH (ORTHORHOMBIC CRYSTAL FORM)
Descriptor:Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Assenberg, R., Ren, J., Verma, A., Walter, T.S., Alderton, D., Hurrelbrink, R.J., Fuller, S.D., Owens, R.J., Stuart, D.I., Grimes, J.M., Oxford Protein Production Facility (OPPF)
Deposit date:2007-05-14
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2PX8
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CRYSTAL STRUCTURE OF THE MURRAY VALLEY ENCEPHALITIS VIRUS NS5 2'-O METHYLTRANSFERASE DOMAIN IN COMPLEX WITH SAH AND 7M-GTP
Descriptor:Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, TRIPHOSPHATE, ...
Authors:Assenberg, R., Ren, J., Verma, A., Walter, T.S., Alderton, D., Hurrelbrink, R.J., Fuller, S.D., Owens, R.J., Stuart, D.I., Grimes, J.M., Oxford Protein Production Facility (OPPF)
Deposit date:2007-05-14
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2PXA
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CRYSTAL STRUCTURE OF THE MURRAY VALLEY ENCEPHALITIS VIRUS NS5 2'-O METHYLTRANSFERASE DOMAIN IN COMPLEX WITH SAH AND GTPG
Descriptor:Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], GUANOSINE-5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Assenberg, R., Ren, J., Verma, A., Walter, T.S., Alderton, D., Hurrelbrink, R.J., Fuller, S.D., Owens, R.J., Stuart, D.I., Grimes, J.M., Oxford Protein Production Facility (OPPF)
Deposit date:2007-05-14
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2PXC
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CRYSTAL STRUCTURE OF THE MURRAY VALLEY ENCEPHALITIS VIRUS NS5 2'-O METHYLTRANSFERASE DOMAIN IN COMPLEX WITH SAM AND GTPA
Descriptor:Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], S-ADENOSYLMETHIONINE, GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE
Authors:Assenberg, R., Ren, J., Verma, A., Walter, T.S., Alderton, D., Hurrelbrink, R.J., Fuller, S.D., Owens, R.J., Stuart, D.I., Grimes, J.M., Oxford Protein Production Facility (OPPF)
Deposit date:2007-05-14
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2WV9
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CRYSTAL STRUCTURE OF THE NS3 PROTEASE-HELICASE FROM MURRAY VALLEY ENCEPHALITIS VIRUS
Descriptor:FLAVIVIRIN PROTEASE NS2B REGULATORY SUBUNIT, FLAVIVIRIN PROTEASE NS3 CATALYTIC SUBUNIT
Authors:Assenberg, R., Mastrangelo, E., Walter, T.S., Verma, A., Milani, M., Owens, R.J., Stuart, D.I., Grimes, J.M., Mancini, E.J.
Deposit date:2009-10-15
Release date:2009-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of a Novel Conformational State of the Flavivirus Ns3 Protein: Implications for Polyprotein Processing and Viral Replication.
J.Virol., 83, 2009
2WZL
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THE STRUCTURE OF THE N-RNA BINDING DOMAIN OF THE MOKOLA VIRUS PHOSPHOPROTEIN
Descriptor:PHOSPHOPROTEIN, GLYCEROL
Authors:Assenberg, R., Delmas, O., Ren, J., Vidalain, P., Verma, A., Larrous, F., Graham, S., Tangy, F., Grimes, J., Bourhy, H.
Deposit date:2009-11-30
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of the N-RNA Binding Domain of the Mokola Virus Phosphoprotein
J.Virol., 84, 2010
2W2S
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STRUCTURE OF THE LAGOS BAT VIRUS MATRIX PROTEIN
Descriptor:MATRIX PROTEIN
Authors:Graham, S.C., Assenberg, R., Delmas, O., Verma, A., Gholami, A., Talbi, C., Owens, R.J., Stuart, D.I., Grimes, J.M., Bourhy, H.
Deposit date:2008-11-03
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Rhabdovirus Matrix Protein Structures Reveal a Novel Mode of Self-Association.
Plos Pathog., 4, 2008
2V8O
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STRUCTURE OF THE MURRAY VALLEY ENCEPHALITIS VIRUS RNA HELICASE TO 1. 9A RESOLUTION
Descriptor:FLAVIVIRIN PROTEASE NS3
Authors:Mancini, E.J., Assenberg, R., Verma, A., Walter, T.S., Tuma, R., Grimes, J.M., Owens, R.J., Stuart, D.I.
Deposit date:2007-08-09
Release date:2007-08-21
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Murray Valley Encephalitis Virus RNA Helicase at 1.9 A Resolution.
Protein Sci., 16, 2007
2CME
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THE CRYSTAL STRUCTURE OF SARS CORONAVIRUS ORF-9B PROTEIN
Descriptor:HYPOTHETICAL PROTEIN 5, DECANE
Authors:Meier, C., Aricescu, A.R., Assenberg, R., Aplin, R.T., Gilbert, R.J.C., Grimes, J.M., Stuart, D.I.
Deposit date:2006-05-06
Release date:2006-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structure of Orf-9B, a Lipid Binding Protein from the Sars Coronavirus.
Structure, 14, 2006
2VVD
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CRYSTAL STRUCTURE OF THE RECEPTOR BINDING DOMAIN OF THE SPIKE PROTEIN P1 FROM BACTERIOPHAGE PM2
Descriptor:SPIKE PROTEIN P1, CALCIUM ION
Authors:Abrescia, N.G.A., Grimes, J.M., Kivela, H.K., Assenberg, R., Sutton, G.C., Butcher, S.J., Bamford, J.K.H., Bamford, D.H., Stuart, D.I.
Deposit date:2008-06-06
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Insights Into Virus Evolution and Membrane Biogenesis from the Structure of the Marine Lipid-Containing Bacteriophage Pm2.
Mol.Cell, 31, 2008
2VVE
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CRYSTAL STRUCTURE OF THE STEM AND RECEPTOR BINDING DOMAIN OF THE SPIKE PROTEIN P1 FROM BACTERIOPHAGE PM2
Descriptor:SPIKE PROTEIN P1, CALCIUM ION, CHLORIDE ION
Authors:Abrescia, N.G.A., Grimes, J.M., Kivela, H.K., Assenberg, R., Sutton, G.C., Butcher, S.J., Bamford, J.K.H., Bamford, D.H., Stuart, D.I.
Deposit date:2008-06-06
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Insights Into Virus Evolution and Membrane Biogenesis from the Structure of the Marine Lipid-Containing Bacteriophage Pm2.
Mol.Cell, 31, 2008
2VVF
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CRYSTAL STRUCTURE OF THE MAJOR CAPSID PROTEIN P2 FROM BACTERIOPHAGE PM2
Descriptor:MAJOR CAPSID PROTEIN P2, CALCIUM ION
Authors:Abrescia, N.G.A., Grimes, J.M., Kivela, H.K., Assenberg, R., Sutton, G.C., Butcher, S.J., Bamford, J.K.H., Bamford, D.H., Stuart, D.I.
Deposit date:2008-06-06
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights Into Virus Evolution and Membrane Biogenesis from the Structure of the Marine Lipid-Containing Bacteriophage Pm2.
Mol.Cell, 31, 2008
2W0C
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X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2
Descriptor:MAJOR CAPSID PROTEIN P2, PROTEIN 2, PROTEIN P3, ...
Authors:Abrescia, N.G.A., Grimes, J.M., Kivela, H.M., Assenberg, R., Sutton, G.C., Butcher, S.J., Bamford, J.K.H., Bamford, D.H., Stuart, D.I.
Deposit date:2008-08-13
Release date:2008-09-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (7 Å)
Cite:Insights Into Virus Evolution and Membrane Biogenesis from the Structure of the Marine Lipid-Containing Bacteriophage Pm2
Mol.Cell, 31, 2008
2W2R
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STRUCTURE OF THE VESICULAR STOMATITIS VIRUS MATRIX PROTEIN
Descriptor:MATRIX PROTEIN
Authors:Graham, S.C., Assenberg, R., Delmas, O., Verma, A., Gholami, A., Talbi, C., Owens, R.J., Stuart, D.I., Grimes, J.M., Bourhy, H.
Deposit date:2008-11-03
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Rhabdovirus Matrix Protein Structures Reveal a Novel Mode of Self-Association.
Plos Pathog., 4, 2008
5JOG
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CRYSTAL STRUCTURE OF CSN5(2-257) IN COMPLEX WITH CNS5I-3
Descriptor:COP9 signalosome complex subunit 5, ZINC ION, 3-(difluoromethyl)-N-{6-[(5S,6S)-6-hydroxy-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl][1,1'-biphenyl]-3-yl}-1-(propan-2-yl)-1H-pyrazole-5-carboxamide
Authors:Renatus, M., Wiesmann, C.
Deposit date:2016-05-02
Release date:2016-11-02
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Targeted inhibition of the COP9 signalosome for treatment of cancer.
Nat Commun, 7, 2016
5JOH
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CRYSTAL STRUCTURE OF CSN5(2-257) IN COMPLEX WITH CNS5I-1B
Descriptor:COP9 signalosome complex subunit 5, ZINC ION, 2'-chloro-6-[(5S,6S)-6-hydroxy-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl][1,1'-biphenyl]-3-carbonitrile, ...
Authors:Renatus, M., Wiesmann, C.
Deposit date:2016-05-02
Release date:2016-11-02
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Targeted inhibition of the COP9 signalosome for treatment of cancer.
Nat Commun, 7, 2016