Author results

1RNR
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AUTOCATALYTIC GENERATION OF DOPA IN THE ENGINEERED PROTEIN R2 F208Y FROM ESCHERICHIA COLI RIBONUCLEOTIDE REDUCTASE AND CRYSTAL STRUCTURE OF THE DOPA-208 PROTEIN
Descriptor:RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, FE (III) ION, MERCURY (II) ION
Authors:Aberg, A., Nordlund, P.
Deposit date:1993-04-26
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Autocatalytic generation of dopa in the engineered protein R2 F208Y from Escherichia coli ribonucleotide reductase and crystal structure of the dopa-208 protein.
Biochemistry, 32, 1993
1ADJ
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HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDINE
Descriptor:HISTIDYL-TRNA SYNTHETASE, SULFATE ION, HISTIDINE
Authors:Cusack, S., Aberg, A.
Deposit date:1997-02-18
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure analysis of the activation of histidine by Thermus thermophilus histidyl-tRNA synthetase.
Biochemistry, 36, 1997
1ADY
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HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDYL-ADENYLATE
Descriptor:HISTIDYL-TRNA SYNTHETASE, SULFATE ION, HISTIDYL-ADENOSINE MONOPHOSPHATE
Authors:Cusack, S., Aberg, A.
Deposit date:1997-02-19
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure analysis of the activation of histidine by Thermus thermophilus histidyl-tRNA synthetase.
Biochemistry, 36, 1997
1914
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SIGNAL RECOGNITION PARTICLE ALU RNA BINDING HETERODIMER, SRP9/14
Descriptor:SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN, PHOSPHATE ION, BETA-MERCAPTOETHANOL
Authors:Birse, D., Kapp, U., Strub, K., Cusack, S., Aberg, A.
Deposit date:1997-11-13
Release date:1998-12-30
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:The crystal structure of the signal recognition particle Alu RNA binding heterodimer, SRP9/14.
EMBO J., 16, 1997
3E67
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MURINE INOS DIMER WITH INHIBITOR 4-MAP BOUND
Descriptor:Nitric oxide synthase, inducible, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stueh, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-14
Release date:2008-10-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E68
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STRUCTURE OF MURINE INOS OXYGENASE DOMAIN WITH INHIBITOR AR-C130232
Descriptor:Nitric oxide synthase, inducible, B-OCTYLGLUCOSIDE, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stueh, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-14
Release date:2008-10-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E6L
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STRUCTURE OF MURINE INOS OXYGENASE DOMAIN WITH INHIBITOR AR-C132283
Descriptor:Nitric oxide synthase, inducible, B-OCTYLGLUCOSIDE, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stueh, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-15
Release date:2008-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E6N
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STRUCTURE OF MURINE INOS OXYGENASE DOMAIN WITH INHIBITOR AR-C125813
Descriptor:Nitric oxide synthase, inducible, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stueh, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-15
Release date:2008-10-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E6O
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STRUCTURE OF MURINE INOS OXYGENASE DOMAIN WITH INHIBITOR AR-C124355
Descriptor:Nitric oxide synthase, inducible, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stueh, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-15
Release date:2008-10-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E6T
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STRUCTURE OF MURINE INOS OXYGENASE DOMAIN WITH INHIBITOR AR-C118901
Descriptor:Nitric oxide synthase, inducible, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stueh, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-15
Release date:2008-10-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E7G
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STRUCTURE OF HUMAN INOSOX WITH INHIBITOR AR-C95791
Descriptor:Nitric oxide synthase, inducible, ZINC ION, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stueh, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-18
Release date:2008-10-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E7I
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STRUCTURE OF MURINE INOS OXYGENASE DOMAIN WITH INHIBITOR AR-C94864
Descriptor:Nitric oxide synthase, inducible, SULFATE ION, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stuehr, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-18
Release date:2008-10-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E7M
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STRUCTURE OF MURINE INOS OXYGENASE DOMAIN WITH INHIBITOR AR-C95791
Descriptor:Nitric oxide synthase, inducible, ZINC ION, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stuehr, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-18
Release date:2008-10-07
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E7S
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STRUCTURE OF BOVINE ENOS OXYGENASE DOMAIN WITH INHIBITOR AR-C95791
Descriptor:Nitric oxide synthase, endothelial, ZINC ION, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stuehr, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-18
Release date:2008-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E7T
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STRUCTURE OF MURINE INOS OXYGENASE DOMAIN WITH INHIBITOR AR-C102222
Descriptor:Nitric oxide synthase, inducible, SULFATE ION, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stuehr, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-18
Release date:2008-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3EAH
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STRUCTURE OF INHIBITED HUMAN ENOS OXYGENASE DOMAIN
Descriptor:Nitric oxide synthase, endothelial, HEME C, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stuehr, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-25
Release date:2008-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3EAI
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STRUCTURE OF INHIBITED MURINE INOS OXYGENASE DOMAIN
Descriptor:Nitric oxide synthase, inducible, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stuehr, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-25
Release date:2008-10-07
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3EBD
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STRUCTURE OF INHIBITED MURINE INOS OXYGENASE DOMAIN
Descriptor:Nitric oxide synthase, inducible, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stuehr, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-27
Release date:2008-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3EBF
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STRUCTURE OF INHIBITED MURINE INOS OXYGENASE DOMAIN
Descriptor:Nitric oxide synthase, inducible, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stuehr, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-27
Release date:2008-10-07
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3EJ8
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STRUCTURE OF DOUBLE MUTANT OF HUMAN INOS OXYGENASE DOMAIN WITH BOUND IMMIDAZOLE
Descriptor:Nitric oxide synthase, inducible, HEME C, ...
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stuehr, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-09-17
Release date:2008-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
1M8D
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INDUCIBLE NITRIC OXIDE SYNTHASE WITH CHLORZOXAZONE BOUND
Descriptor:Inducible Nitric Oxide Synthase, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Rosenfeld, R.J., Garcin, E.D., Panda, K., Andersson, G., Aberg, A., Wallace, A.V., Stuehr, D.J., Tainer, J.A., Getzoff, E.D.
Deposit date:2002-07-24
Release date:2002-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency
Biochemistry, 41, 2002
1M8E
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INDUCIBLE NITRIC OXIDE SYNTHASE WITH 7-NITROINDAZOLE BOUND
Descriptor:inducible Nitric oxide synthase, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ...
Authors:Rosenfeld, R.J., Garcin, E.D., Panda, K., Andersson, G., Aberg, A., Wallace, A.V., Stuehr, D.J., Tainer, J.A., Getzoff, E.D.
Deposit date:2002-07-24
Release date:2002-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency
Biochemistry, 41, 2002
1M8H
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INDUCIBLE NITRIC OXIDE SYNTHASE WITH 6-NITROINDAZOLE BOUND
Descriptor:inducible Nitric oxide synthase, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Rosenfeld, R.J., Garcin, E.D., Panda, K., Andersson, G., Aberg, A., Wallace, A.V., Stuehr, D.J., Tainer, J.A., Getzoff, E.D.
Deposit date:2002-07-24
Release date:2002-08-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency
Biochemistry, 41, 2002
1M8I
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INDUCIBLE NITRIC OXIDE SYNTHASE WITH 5-NITROINDAZOLE BOUND
Descriptor:inducible Nitric oxide synthase, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ...
Authors:Rosenfeld, R.J., Garcin, E.D., Panda, K., Andersson, G., Aberg, A., Wallace, A.V., Stuehr, D.J., Tainer, J.A., Getzoff, E.D.
Deposit date:2002-07-24
Release date:2002-08-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency
Biochemistry, 41, 2002
1M9J
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HUMAN ENDOTHELIAL NITRIC OXIDE SYNTHASE WITH CHLORZOXAZONE BOUND
Descriptor:endothelial Nitric-oxide synthase, ZINC ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Rosenfeld, R.J., Garcin, E.D., Panda, K., Andersson, G., Aberg, A., Wallace, A.V., Stuehr, D.J., Tainer, J.A., Getzoff, E.D.
Deposit date:2002-07-29
Release date:2002-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency
Biochemistry, 41, 2002
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