Author results

2D35
  • Download 2d35
  • View 2d35
Molmil generated image of 2d35
SOLUTION STRUCTURE OF CELL DIVISION REACTIVATION FACTOR, CEDA
Descriptor:Cell division activator cedA
Authors:Abe, Y., Watanabe, N., Matsuda, Y., Yoshida, Y., Katayama, T., Ueda, T.
Deposit date:2005-09-26
Release date:2006-12-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Analysis and Molecular Interaction of Cell Division Reactivation Factor, CedA from Escherichia coli
To be Published
3WW5
  • Download 3ww5
  • View 3ww5
Molmil generated image of 3ww5
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME MUTANT N46E/D52S
Descriptor:Lysozyme C, CHLORIDE ION
Authors:Abe, Y., Kubota, M., Ito, Y., Imoto, T., Ueda, T.
Deposit date:2014-06-17
Release date:2015-06-17
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Effect on catalysis by replacement of catalytic residue from hen egg white lysozyme to Venerupis philippinarum lysozyme
Protein Sci., 2016
3WW6
  • Download 3ww6
  • View 3ww6
Molmil generated image of 3ww6
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME MUTANT N46D/D52S
Descriptor:Lysozyme C, CHLORIDE ION
Authors:Abe, Y., Kubota, M., Ito, Y., Imoto, T., Ueda, T.
Deposit date:2014-06-17
Release date:2015-06-17
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Effect on catalysis by replacement of catalytic residue from hen egg white lysozyme to Venerupis philippinarum lysozyme
Protein Sci., 2016
2E0G
  • Download 2e0g
  • View 2e0g
Molmil generated image of 2e0g
DNAA N-TERMINAL DOMAIN
Descriptor:Chromosomal replication initiator protein dnaA
Authors:Abe, Y., Katayama, T., Ueda, T., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-10-07
Release date:2007-05-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and Function of DnaA N-Terminal Domains: Specific Sites and Mechanisms in Inter-DnaA Interaction and in DnaB Helicase Loading on oriC
To be Published
1OM2
  • Download 1om2
  • View 1om2
Molmil generated image of 1om2
SOLUTION NMR STRUCTURE OF THE MITOCHONDRIAL PROTEIN IMPORT RECEPTOR TOM20 FROM RAT IN A COMPLEX WITH A PRESEQUENCE PEPTIDE DERIVED FROM RAT ALDEHYDE DEHYDROGENASE (ALDH)
Descriptor:PROTEIN (MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20), PROTEIN (MITOCHONDRIAL ALDEHYDE DEHYDROGENASE)
Authors:Abe, Y., Shodai, T., Muto, T., Mihara, K., Torii, H., Nishikawa, S., Endo, T., Kohda, D.
Deposit date:1999-04-23
Release date:2000-02-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20.
Cell(Cambridge,Mass.), 100, 2000
5YCQ
  • Download 5ycq
  • View 5ycq
Molmil generated image of 5ycq
UNIQUE SPECIFICITY-ENHANCING FACTOR FOR THE AAA+ LON PROTEASE
Descriptor:Heat shock protein HspQ
Authors:Abe, Y., Shioi, S., Kita, S., Nakata, H., Maenaka, K., Kohda, D., Katayama, T., Ueda, T.
Deposit date:2017-09-08
Release date:2018-04-11
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:X-ray crystal structure of Escherichia coli HspQ, a protein involved in the retardation of replication initiation
FEBS Lett., 591, 2017
2RU8
  • Download 2ru8
  • View 2ru8
Molmil generated image of 2ru8
DNAT C-TERMINAL DOMAIN
Descriptor:Primosomal protein 1
Authors:Abe, Y., Tani, J., Fujiyama, S., Urabe, M., Sato, K., Aramaki, T., Katayama, T., Ueda, T.
Deposit date:2014-01-29
Release date:2014-10-08
Last modified:2014-10-22
Method:SOLUTION NMR
Cite:Structure and mechanism of the primosome protein DnaT: functional structures for homotrimerization, dissociation of ssDNA from PriB-ssDNA complex and formation of DnaT-ssDNA complex
Febs J., 2014
2RUP
  • Download 2rup
  • View 2rup
Molmil generated image of 2rup
SOLUTION STRUCTURE OF RAT P2X4 RECEPTOR HEAD DOMAIN
Descriptor:P2X purinoceptor 4
Authors:Abe, Y., Igawa, T., Tsuda, M., Inoue, K., Ueda, T.
Deposit date:2014-11-12
Release date:2015-02-04
Last modified:2018-10-17
Method:SOLUTION NMR
Cite:Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding
FEBS Lett., 589, 2015
2Z9S
  • Download 2z9s
  • View 2z9s
Molmil generated image of 2z9s
CRYSTAL STRUCTURE ANALYSIS OF RAT HBP23/PEROXIREDOXIN I, CYS52SER MUTANT
Descriptor:Peroxiredoxin-1
Authors:Matsumura, T., Okamoto, K., Nishino, T., Abe, Y.
Deposit date:2007-09-25
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Dimer-Oligomer Interconversion of Wild-type and Mutant Rat 2-Cys Peroxiredoxin: DISULFIDE FORMATION AT DIMER-DIMER INTERFACES IS NOT ESSENTIAL FOR DECAMERIZATION
J.Biol.Chem., 283, 2008
2DQA
  • Download 2dqa
  • View 2dqa
Molmil generated image of 2dqa
CRYSTAL STRUCTURE OF TAPES JAPONICA LYSOZYME
Descriptor:Lysozyme, PLATINUM (II) ION, BETA-D-GLUCOSE, ...
Authors:Goto, T., Kakuta, Y., Abe, Y., Takeshita, K., Imoto, T., Ueda, T.
Deposit date:2006-05-24
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of Tapes japonica Lysozyme with Substrate Analogue: STRUCTURAL BASIS OF THE CATALYTIC MECHANISM AND MANIFESTATION OF ITS CHITINASE ACTIVITY ACCOMPANIED BY QUATERNARY STRUCTURAL CHANGE
J.Biol.Chem., 282, 2007
4YZF
  • Download 4yzf
  • View 4yzf
Molmil generated image of 4yzf
CRYSTAL STRUCTURE OF THE ANION EXCHANGER DOMAIN OF HUMAN ERYTHROCYTE BAND 3
Descriptor:Band 3 anion transport protein, FAB fragment of Immunoglobulin (IgG) molecule, 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid}
Authors:Alguel, Y., Arakawa, T., Yugiri, T.K., Iwanari, H., Hatae, H., Iwata, M., Abe, Y., Hino, T., Suno, C.I., Kuma, H., Kang, D., Murata, T., Hamakubo, T., Cameron, A.D., Kobayashi, T., Hamasaki, N., Iwata, S.
Deposit date:2015-03-25
Release date:2015-11-04
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the anion exchanger domain of human erythrocyte band 3.
Science, 350, 2015
5A16
  • Download 5a16
  • View 5a16
Molmil generated image of 5a16
CRYSTAL STRUCTURE OF FAB4201 RAISED AGAINST HUMAN ERYTHROCYTE ANION EXCHANGER 1
Descriptor:FAB4201 HEAVY CHAIN
Authors:Arakawa, T., Kobayashi-Yugiri, T., Alguel, Y., Weyand, S., Iwanari, H., Hatae, H., Iwata, M., Abe, Y., Hino, T., Ikeda-Suno, C., Kuma, H., Kang, D., Murata, T., Hamakubo, T., Cameron, A., Kobayashi, T., Hamasaki, N., Iwata, S.
Deposit date:2015-04-28
Release date:2015-06-10
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Anion Exchanger Domain of Human Erythrocyte Band 3
Science, 350, 2015
1B9O
  • Download 1b9o
  • View 1b9o
Molmil generated image of 1b9o
HUMAN ALPHA-LACTALBUMIN, LOW TEMPERATURE FORM
Descriptor:PROTEIN (ALPHA-LACTALBUMIN), CALCIUM ION
Authors:Harata, K., Abe, Y., Muraki, M.
Deposit date:1999-02-14
Release date:1999-03-31
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystallographic evaluation of internal motion of human alpha-lactalbumin refined by full-matrix least-squares method.
J.Mol.Biol., 287, 1999
1JSE
  • Download 1jse
  • View 1jse
Molmil generated image of 1jse
FULL-MATRIX LEAST-SQUARES REFINEMENT OF TURKEY LYSOZYME
Descriptor:LYSOZYME, N-PROPANOL
Authors:Harata, K., Abe, Y., Muraki, M.
Deposit date:1998-01-05
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Full-matrix least-squares refinement of lysozymes and analysis of anisotropic thermal motion.
Proteins, 30, 1998
1JSF
  • Download 1jsf
  • View 1jsf
Molmil generated image of 1jsf
FULL-MATRIX LEAST-SQUARES REFINEMENT OF HUMAN LYSOZYME
Descriptor:LYSOZYME, NITRATE ION
Authors:Harata, K., Abe, Y., Muraki, M.
Deposit date:1998-01-05
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Full-matrix least-squares refinement of lysozymes and analysis of anisotropic thermal motion.
Proteins, 30, 1998
1QQ2
  • Download 1qq2
  • View 1qq2
Molmil generated image of 1qq2
CRYSTAL STRUCTURE OF A MAMMALIAN 2-CYS PEROXIREDOXIN, HBP23.
Descriptor:THIOREDOXIN PEROXIDASE 2, CHLORIDE ION
Authors:Hirotsu, S., Abe, Y., Okada, K., Nagahara, N., Hori, H., Nishino, T., Hakoshima, T.
Deposit date:1999-06-10
Release date:1999-10-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product.
Proc.Natl.Acad.Sci.USA, 96, 1999
1WOC
  • Download 1woc
  • View 1woc
Molmil generated image of 1woc
CRYSTAL STRUCTURE OF PRIB
Descriptor:Primosomal replication protein n
Authors:Shioi, S., Ose, T., Maenaka, K., Abe, Y., Kohda, D., Katayama, T., Ueda, T.
Deposit date:2004-08-13
Release date:2005-01-25
Last modified:2012-12-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a biologically functional form of PriB from Escherichia coli reveals a potential single-stranded DNA-binding site
Biochem.Biophys.Res.Commun., 326, 2005
2RT6
  • Download 2rt6
  • View 2rt6
Molmil generated image of 2rt6
BACKBONE 1H, 13C, AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR PRIC N-TERMINAL DOMAIN
Descriptor:Primosomal replication protein N''
Authors:Aramaki, T., Abe, Y., Katayama, T., Ueda, T.
Deposit date:2013-04-24
Release date:2013-08-07
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal domain of a replication restart primosome factor, PriC, in Escherichia coli.
Protein Sci., 2013
5WQV
  • Download 5wqv
  • View 5wqv
Molmil generated image of 5wqv
CRYSTAL STRUCTURE OF PRIB MUTANT - S55A
Descriptor:Primosomal replication protein N
Authors:Fujiyama, S., Shiroishi, M., Katayama, T., Abe, Y., Ueda, T.
Deposit date:2016-11-28
Release date:2017-11-29
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structure of PriB mutant - S55A
To Be Published
5Y25
  • Download 5y25
  • View 5y25
Molmil generated image of 5y25
EGFR KINASE DOMAIN MUTANT (T790M/L858R) WITH COVALENT LIGAND NS-062
Descriptor:Epidermal growth factor receptor, (2R)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamide
Authors:Shiroishi, M., Abe, Y., Caaveiro, J.M.M., Sakamoto, S., Morimoto, S., Fuchida, H., Shindo, N., Ojida, A.
Deposit date:2017-07-24
Release date:2018-07-25
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:EGFR kinase domain mutant (T790M/L858R) with covalent ligand NS-062
To Be Published
2ZTB
  • Download 2ztb
  • View 2ztb
Molmil generated image of 2ztb
CRYSTAL STRUCTURE OF THE PARASPORIN-2 BACILLUS THURINGIENSIS TOXIN THAT RECOGNIZES CANCER CELLS
Descriptor:Crystal protein, LUTETIUM (III) ION, GLYCEROL, ...
Authors:Akiba, T.
Deposit date:2008-09-29
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of the parasporin-2 Bacillus thuringiensis toxin that recognizes cancer cells
J.Mol.Biol., 386, 2009
2E7A
  • Download 2e7a
  • View 2e7a
Molmil generated image of 2e7a
TNF RECEPTOR SUBTYPE ONE-SELECTIVE TNF MUTANT WITH ANTAGONISTIC ACTIVITY
Descriptor:Tumor necrosis factor
Authors:Mukai, Y., Yamagata, Y., Tsutsumi, Y.
Deposit date:2007-01-09
Release date:2007-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist
J.Biol.Chem., 283, 2008
2ZJC
  • Download 2zjc
  • View 2zjc
Molmil generated image of 2zjc
TNFR1 SELECTVE TNF MUTANT; R1-6
Descriptor:Tumor necrosis factor, GLYCEROL
Authors:Mukai, Y., Yamagata, Y., Tsutsumi, Y.
Deposit date:2008-03-05
Release date:2009-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-Function Relationship of Tumor Necrosis Factor (TNF) and Its Receptor Interaction Based on 3D Structural Analysis of a Fully Active TNFR1-Selective TNF Mutant
J.Mol.Biol., 385, 2009
2ZPX
  • Download 2zpx
  • View 2zpx
Molmil generated image of 2zpx
TNF RECEPTOR SUBTYPE ONE-SELECTIVE TNF MUTANT WITH ANTAGONISTIC ACTIVITY; R1ANTTNF-T8
Descriptor:Tumor necrosis factor
Authors:Mukai, Y., Nakamura, T., Yamagata, Y., Tsutsumi, Y.
Deposit date:2008-07-29
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists
J.Biochem., 146, 2009
3VJK
  • Download 3vjk
  • View 3vjk
Molmil generated image of 3vjk
CRYSTAL STRUCTURE OF HUMAN DEPIPTIDYL PEPTIDASE IV (DPP-4) IN COMPLEX WITH MP-513
Descriptor:Dipeptidyl peptidase 4, {(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-yl}(1,3-thiazolidin-3-yl)methanone, N-ACETYL-D-GLUCOSAMINE
Authors:Akahoshi, F., Kishida, H., Miyaguchi, I., Yoshida, T., Ishii, S.
Deposit date:2011-10-24
Release date:2012-10-24
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Bioorg.Med.Chem., 20, 2012
<12>