Author results

3QZR
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HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT E71A IN COMPLEX WITH RUPINTRIVIR
Descriptor:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, 1,2-ETHANEDIOL
Authors:Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S.
Deposit date:2011-03-07
Release date:2011-08-10
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.039 Å)
Cite:Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
6GKE
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ALEURIA AURANTIA LECTIN AAL N224Q MUTANT IN COMPLEX WITH FUCALPHA1-6GLCNAC
Descriptor:Fucose-specific lectin, ALPHA-L-FUCOSE, GLYCEROL, ...
Authors:Houser, J., Wimmerova, M., Herrera, H., Mehta, A.S.
Deposit date:2018-05-19
Release date:2019-06-19
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Structural dynamics and applications of a fucose-binding lectin with enhanced binding to alpha-1,6-linked core fucosylation
To Be Published
6G8A
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LYSOZYME SOLVED BY NATIVE SAD FROM A DATASET COLLECTED IN 5 SECONDS AT 1 A WAVELENGTH WITH JUNGFRAU DETECTOR
Descriptor:Lysozyme C, CHLORIDE ION, SODIUM ION, ...
Authors:Leonarski, F., Olieric, V., Vera, L., Redford, S., Wang, M.
Deposit date:2018-04-08
Release date:2018-08-01
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.143 Å)
Cite:Fast and accurate data collection for macromolecular crystallography using the JUNGFRAU detector.
Nat. Methods, 15, 2018
2WSO
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STRUCTURE OF CERULEAN FLUORESCENT PROTEIN AT PHYSIOLOGICAL PH
Descriptor:GREEN FLUORESCENT PROTEIN
Authors:Lelimousin, M., Noirclerc-Savoye, M., Lazareno-Saez, C., Paetzold, B., Le Vot, S., Chazal, R., Macheboeuf, P., Field, M.J., Bourgeois, D., Royant, A.
Deposit date:2009-09-08
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Intrinsic Dynamics in Ecfp and Cerulean Control Fluorescence Quantum Yield.
Biochemistry, 48, 2009
1DJT
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ATOMIC RESOLUTION STRUCTURE OF SCORPION ALPHA-LIKE TOXIN BMK M1 IN A NEW CRYSTAL FORM
Descriptor:ALPHA-LIKE NEUROTOXIN BMK M1
Authors:Wang, D.-C., He, X.-L.
Deposit date:1999-12-05
Release date:2000-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Atomic Resolution Structure of Scorpion Alpha-Like Toxin BmK M1 in a New Crystal Form
To be Published
3PPT
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REP1-NXSQ FATTY ACID TRANSPORTER
Descriptor:ReP1-NCXSQ, PALMITOLEIC ACID
Authors:Berberian, G., Bollo, M., Howard, E., Cousido-Siah, A., Mitschler, A., Ayoub, D., Sanglier-Cianferani, S., Van Dorsselaer, A., DiPolo, R., Beauge, L., Petrova, T., Schulze-Briese, C., Wang, M., Podjarny, A.
Deposit date:2010-11-25
Release date:2011-12-21
Last modified:2018-08-15
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Structural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na+/Ca2+ exchanger.
Acta Crystallogr.,Sect.D, 68, 2012
1SN4
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STRUCTURE OF SCORPION NEUROTOXIN BMK M4
Descriptor:PROTEIN (NEUROTOXIN BMK M4), ACETATE ION
Authors:He, X.L., Li, H.M., Liu, X.Q., Zeng, Z.H., Wang, D.C.
Deposit date:1998-11-11
Release date:1999-11-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel.
J.Mol.Biol., 292, 1999
2QDY
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CRYSTAL STRUCTURE OF FE-TYPE NHASE FROM RHODOCOCCUS ERYTHROPOLIS AJ270
Descriptor:Nitrile hydratase subunit alpha, Nitrile hydratase subunit beta, FE (III) ION, ...
Authors:Song, L., Shi, J., Xue, Z., Wang, M.-X., Qian, S.
Deposit date:2007-06-22
Release date:2008-05-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:High resolution X-ray molecular structure of the nitrile hydratase from Rhodococcus erythropolis AJ270 reveals posttranslational oxidation of two cysteines into sulfinic acids and a novel biocatalytic nitrile hydration mechanism
Biochem.Biophys.Res.Commun., 362, 2007
3R0F
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HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT H133G IN COMPLEX WITH RUPINTRIVIR
Descriptor:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, 1,2-ETHANEDIOL
Authors:Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S.
Deposit date:2011-03-08
Release date:2011-08-10
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.3083 Å)
Cite:Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
1KV0
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CIS/TRANS ISOMERIZATION OF NON-PROLYL PEPTIDE BOND OBSERVED IN CRYSTAL STRUCTURE OF AN SCORPION TOXIN
Descriptor:Alpha-like toxin BmK-M7
Authors:Guan, R.J., He, X.L., Wang, M., Xiang, Y., Wang, D.C.
Deposit date:2002-01-23
Release date:2003-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural mechanism governing cis and trans isomeric states and an intramolecular switch for cis/trans isomerization of a non-proline peptide bond observed in crystal structures of scorpion toxins.
J.Mol.Biol., 341, 2004
1T7E
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CRYSTAL STRUCTURE OF MUTANT PRO9SER OF SCORPION ALPHA-LIKE NEUROTOXIN BMK M1 FROM BUTHUS MARTENSII KARSCH
Descriptor:Alpha-like neurotoxin BmK-I, PHOSPHATE ION
Authors:Xiang, Y., Guan, R.J., He, X.L., Wang, C.G., Wang, M., Zhang, Y., Sundberg, E.J., Wang, D.C.
Deposit date:2004-05-09
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
J.Mol.Biol., 341, 2004
5ZHO
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HUMAN GROUP C ROTAVIRUS VP8*S RECOGNIZE TYPE A HISTO-BLOOD GROUP ANTIGENS AS LIGANDS
Descriptor:Outer capsid protein VP8*, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, ALPHA D-GALACTOSE, ...
Authors:Sun, X., Duan, Z., Qi, J.
Deposit date:2018-03-13
Release date:2018-04-11
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Human Group C Rotavirus VP8*s Recognize Type A Histo-Blood Group Antigens as Ligands.
J. Virol., 92, 2018
6DL2
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BRD4 BROMODOMAIN 1 IN COMPLEX WITH HYB157
Descriptor:Bromodomain-containing protein 4, 3-benzyl-2,9-dimethyl-4H,6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,4]oxazepine, 1,2-ETHANEDIOL
Authors:Meagher, J.L., Stuckey, J.A.
Deposit date:2018-05-31
Release date:2019-04-17
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression.
J. Med. Chem., 61, 2018
4U3L
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OCTAMERIC RNA DUPLEX CO-CRYSTALLIZED IN CALCIUM(II)CHLORIDE
Descriptor:RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3'), CALCIUM ION
Authors:Schaffer, M.F., Spingler, B., Schnabl, J., Peng, G., Olieric, V., Sigel, R.K.O.
Deposit date:2014-07-22
Release date:2015-07-29
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
5LIN
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LYSOZYME, COLLECTED AT ROTATION 1 DEGREE PER SECOND
Descriptor:Lysozyme C, CHLORIDE ION
Authors:Casanas, A., Finke, A., Wang, M.
Deposit date:2016-07-15
Release date:2016-08-03
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.496 Å)
Cite:EIGER detector: application in macromolecular crystallography.
Acta Crystallogr D Struct Biol, 72, 2016
5LIO
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LYSOZYME, COLLECTED AT ROTATION 360 DEGREE PER SECOND
Descriptor:Lysozyme C, CHLORIDE ION
Authors:Casanas, A., Finke, A., Wang, M.
Deposit date:2016-07-15
Release date:2016-08-03
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.496 Å)
Cite:EIGER detector: application in macromolecular crystallography.
Acta Crystallogr D Struct Biol, 72, 2016
1T7A
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CRYSTAL STRUCTURE OF MUTANT LYS8ASP OF SCORPION ALPHA-LIKE NEUROTOXIN BMK M1 FROM BUTHUS MARTENSII KARSCH
Descriptor:Alpha-like neurotoxin BmK-I
Authors:Xiang, Y., Guan, R.J., He, X.L., Wang, C.G., Wang, M., Zhang, Y., Sundberg, E.J., Wang, D.C.
Deposit date:2004-05-08
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
J.Mol.Biol., 341, 2004
5D53
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IN MESO IN SITU SERIAL X-RAY CRYSTALLOGRAPHY STRUCTURE OF INSULIN AT 100 K
Descriptor:Insulin B chain, Insulin A chain, PHOSPHATE ION, ...
Authors:Huang, C.-Y., Olieric, V., Diederichs, K., Wang, M., Caffrey, M.
Deposit date:2015-08-10
Release date:2016-01-13
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures.
Acta Crystallogr D Struct Biol, 72, 2016
5D54
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IN MESO X-RAY CRYSTALLOGRAPHY STRUCTURE OF INSULIN AT 100 K
Descriptor:Insulin B chain, Insulin A chain, PHOSPHATE ION, ...
Authors:Huang, C.-Y., Olieric, V., Wang, M., Caffrey, M.
Deposit date:2015-08-10
Release date:2016-01-13
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures.
Acta Crystallogr D Struct Biol, 72, 2016
5D5F
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IN MESO IN SITU SERIAL X-RAY CRYSTALLOGRAPHY STRUCTURE OF LYSOZYME BY BROMINE-SAD AT 100 K
Descriptor:Lysozyme C, BROMIDE ION, SODIUM ION, ...
Authors:Huang, C.-Y., Olieric, V., Diederichs, K., Wang, M., Caffrey, M.
Deposit date:2015-08-10
Release date:2016-01-13
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures.
Acta Crystallogr D Struct Biol, 72, 2016
5GNF
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CRYSTAL STRUCTURE OF ANTI-CRISPR PROTEIN ACRF3
Descriptor:Uncharacterized protein AcrF3, CALCIUM ION
Authors:Wang, J., Wang, Y.
Deposit date:2016-07-20
Release date:2016-09-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
5NJM
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LYSOZYME ROOM-TEMPERATURE STRUCTURE DETERMINED BY SERIAL MILLISECOND CRYSTALLOGRAPHY
Descriptor:Lysozyme C
Authors:Weinert, T., Vera, L., Marsh, M., James, D., Gashi, D., Nogly, P., Jaeger, K., Standfuss, J.
Deposit date:2017-03-29
Release date:2017-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.
Nat Commun, 8, 2017
6C7R
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BRD4 BD1 IN COMPLEX WITH COMPOUND CF53
Descriptor:Bromodomain-containing protein 4, N-(3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-6-methoxy-2-methyl-9H-pyrimido[4,5-b]indol-4-amine
Authors:Meagher, J.L., Stuckey, J.A.
Deposit date:2018-01-23
Release date:2018-08-01
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor.
J. Med. Chem., 61, 2018
6IF3
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COMPLEX STRUCTURE OF RAB35 AND ITS EFFECTOR ACAP2
Descriptor:Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, Ras-related protein Rab-35, ...
Authors:Lin, L., Zhu, J., Zhang, R.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
4U78
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OCTAMERIC RNA DUPLEX SOAKED IN COPPER(II)CHLORIDE
Descriptor:RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3'), COPPER (II) ION, CALCIUM ION
Authors:Schaffer, M.F., Spingler, B., Schnabl, J., Peng, G., Olieric, V., Sigel, R.K.O.
Deposit date:2014-07-30
Release date:2015-08-26
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016