Author results

6RQO
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STEADY-STATE-SMX ACTIVATED STATE STRUCTURE OF BACTERIORHODOPSIN
Descriptor:Bacteriorhodopsin, RETINAL
Authors:Weinert, T., Skopintsev, P., James, D., Kekilli, D., Furrer, A., Bruenle, S., Mous, S., Nogly, P., Standfuss, J.
Deposit date:2019-05-16
Release date:2019-07-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Proton uptake mechanism in bacteriorhodopsin captured by serial synchrotron crystallography.
Science, 365, 2019
6RQP
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STEADY-STATE-SMX DARK STATE STRUCTURE OF BACTERIORHODOPSIN
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, ...
Authors:Weinert, T., Skopintsev, P., James, D., Kekilli, D., Furrer, A., Bruenle, S., Mous, S., Nogly, P., Standfuss, J.
Deposit date:2019-05-16
Release date:2019-07-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Proton uptake mechanism in bacteriorhodopsin captured by serial synchrotron crystallography.
Science, 365, 2019
6RPH
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TR-SMX OPEN STATE STRUCTURE (10-15MS) OF BACTERIORHODOPSIN
Descriptor:Bacteriorhodopsin, RETINAL
Authors:Weinert, T., Skopintsev, P., James, D., Kekilli, D., Furrer, A., Bruenle, S., Mous, S., Nogly, P., Standfuss, J.
Deposit date:2019-05-14
Release date:2019-07-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Proton uptake mechanism in bacteriorhodopsin captured by serial synchrotron crystallography.
Science, 365, 2019
6K1S
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DISCOVERY OF POTENT AND SELECTIVE COVALENT PROTEIN ARGININE METHYLTRANSFERASE (PRMT5) INHIBITORS
Descriptor:Protein arginine N-methyltransferase 5, Methylosome protein 50, 2-[[7-[(2~{R},3~{R},4~{S},5~{R})-5-[(~{R})-(4-chlorophenyl)-oxidanyl-methyl]-3,4-bis(oxidanyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidin-4-yl]amino]ethanal, ...
Authors:Tong, S., Lin, H.
Deposit date:2019-05-12
Release date:2019-06-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors.
Acs Med.Chem.Lett., 2019
6RNJ
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TR-SMX CLOSED STATE STRUCTURE (0-5MS) OF BACTERIORHODOPSIN
Descriptor:Bacteriorhodopsin, RETINAL
Authors:Weinert, T., Skopintsev, P., James, D., Kekilli, D., Furrer, F., Bruenle, S., Mous, S., Nogly, P., Standfuss, J.
Deposit date:2019-05-08
Release date:2019-07-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Proton uptake mechanism in bacteriorhodopsin captured by serial synchrotron crystallography.
Science, 365, 2019
6OM3
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CRYSTAL STRUCTURE OF THE ORC1 BAH DOMAIN IN COMPLEX WITH A NUCLEOSOME CORE PARTICLE
Descriptor:Histone H3.2, Histone H4, Histone H2A, ...
Authors:De Ioannes, P.E., Wang, M., Armache, K.-J.
Deposit date:2019-04-18
Release date:2019-07-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure and function of the Orc1 BAH-nucleosome complex.
Nat Commun, 10, 2019
6JU2
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO CRNA PROMOTER IN CLASS 1
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-04-12
Release date:2019-06-12
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 2019
6JU3
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO CRNA PROMOTER IN CLASS 2
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-04-12
Release date:2019-06-12
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 2019
6O96
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DOT1L BOUND TO THE H2BK120 UBIQUITINATED NUCLEOSOME
Descriptor:Histone H3.2, Histone H4, Histone H2A, ...
Authors:Valencia-Sanchez, M.I., De Ioannes, P.E., Miao, W., Vasilyev, N., Chen, R., Nudler, E., Armache, J.-P., Armache, K.-J.
Deposit date:2019-03-13
Release date:2019-04-24
Last modified:2019-06-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination.
Mol.Cell, 74, 2019
6JB1
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STRUCTURE OF PANCREATIC ATP-SENSITIVE POTASSIUM CHANNEL BOUND WITH REPAGLINIDE AND ATPGAMMAS AT 3.3A RESOLUTION
Descriptor:ATP-sensitive inward rectifier potassium channel 11, ATP-binding cassette sub-family C member 8 isoform X2, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ...
Authors:Chen, L., Ding, D., Wang, M., Wu, J.-X., Kang, Y.
Deposit date:2019-01-25
Release date:2019-05-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.
Cell Rep, 27, 2019
6JB3
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STRUCTURE OF SUR1 SUBUNIT BOUND WITH REPAGLINIDE
Descriptor:ATP-binding cassette sub-family C member 8 isoform X2, Repaglinide, Digitonin
Authors:Chen, L., Ding, D., Wang, M., Wu, J.-X., Kang, Y.
Deposit date:2019-01-25
Release date:2019-05-22
Method:ELECTRON MICROSCOPY (3.001 Å)
Cite:The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.
Cell Rep, 27, 2019
6I59
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LONG WAVELENGTH NATIVE-SAD PHASING OF SEN1 HELICASE
Descriptor:Helicase SEN1, ADENOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges.
Iucrj, 6, 2019
6I5C
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LONG WAVELENGTH NATIVE-SAD PHASING OF TUBULIN-STATHMIN-TTL COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges.
Iucrj, 6, 2019
6N05
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STRUCTURE OF ANTI-CRISPR PROTEIN, ACRIIC2
Descriptor:AcrIIC2
Authors:Shah, M., Thavalingham, A., Maxwell, K.L., Moraes, T.F.
Deposit date:2018-11-06
Release date:2019-06-05
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
6IOJ
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GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A (APO-FORM)
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase A
Authors:Wang, H., Sun, H., Wang, M.
Deposit date:2018-10-30
Release date:2019-07-03
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli
Chem Sci, 2019
6IO4
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SILVER-BOUND GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
Authors:Wang, H., Sun, H., Wang, M.
Deposit date:2018-10-29
Release date:2019-07-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli
Chem Sci, 2019
6IO6
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SILVER-BOUND GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A AT NON-CATALYTIC SITE
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
Authors:Wang, H., Sun, H., Wang, M.
Deposit date:2018-10-29
Release date:2019-07-03
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli
Chem Sci, 2019
6IMM
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CRYO-EM STRUCTURE OF AN ALPHAVIRUS, SINDBIS VIRUS
Descriptor:Spike glycoprotein E1, Spike glycoprotein E2, Assembly protein E3, ...
Authors:Zhang, X., Ma, J., Chen, L.
Deposit date:2018-10-23
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Implication for alphavirus host-cell entry and assembly indicated by a 3.5 angstrom resolution cryo-EM structure.
Nat Commun, 9, 2018
6IFR
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-NTR, ATP BOUND
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFU
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CRYO-EM STRUCTURE OF TYPE III-A CSM-CTR2-DSDNA COMPLEX
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-05-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFY
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR1
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFZ
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR2-SSDNA COMPLEX
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IG0
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR1, ATP BOUND
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFK
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CRYO-EM STRUCTURE OF TYPE III-A CSM-CTR1 COMPLEX, AMPPNP BOUND
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFL
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CRYO-EM STRUCTURE OF TYPE III-A CSM-NTR COMPLEX
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019