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1YT4
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CRYSTAL STRUCTURE OF TEM-76 BETA-LACTAMASE AT 1.4 ANGSTROM RESOLUTION
Descriptor:Beta-lactamase TEM
Authors:Thomas, V.L., Golemi-Kotra, D., Kim, C., Vakulenko, S.B., Mobashery, S., Shoichet, B.K.
Deposit date:2005-02-09
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Consequences of the Inhibitor-Resistant Ser130Gly Substitution in TEM beta-Lactamase.
Biochemistry, 44, 2005
3IWI
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X-RAY CRYSTAL STRUCTURE OF THE EXTENDED-SPECTRUM AMPC OMEGA LOOP INSERTION (H210AAA) MUTANT BETA-LACTAMASE AT 1.64 ANGSTROM RESOLUTION
Descriptor:Beta-lactamase, PHOSPHATE ION
Authors:Shoichet, B.K., Thomas, V.L.
Deposit date:2009-09-02
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structural bases for stability-function tradeoffs in antibiotic resistance.
J.Mol.Biol., 396, 2010
3IWO
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X-RAY CRYSTAL STRUCTURE OF THE EXTENDED-SPECTRUM AMPC Y221G MUTANT BETA-LACTAMASE AT 1.90 ANGSTROM RESOLUTION
Descriptor:Beta-lactamase, SUCROSE, PHOSPHATE ION
Authors:Shoichet, B.K., Thomas, V.L.
Deposit date:2009-09-03
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural bases for stability-function tradeoffs in antibiotic resistance.
J.Mol.Biol., 396, 2010
3IWQ
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X-RAY CRYSTAL STRUCTURE OF THE EXTENDED-SPECTRUM AMPC E219K MUTANT BETA-LACTAMASE AT 1.84 ANGSTROM RESOLUTION
Descriptor:Beta-lactamase, PHOSPHATE ION
Authors:Shoichet, B.K., Thomas, V.L.
Deposit date:2009-09-03
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural bases for stability-function tradeoffs in antibiotic resistance.
J.Mol.Biol., 396, 2010
3IXB
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X-RAY CRYSTAL STRUCTURE OF THE EXTENDED-SPECTRUM AMPC E219K MUTANT BETA-LACTAMASE COMPLEXED WITH BENZO(B)THIOPHENE-2-BORONIC ACID (BZB) AT 1.63 ANGSTROM RESOLUTION
Descriptor:Beta-lactamase, PHOSPHATE ION, BENZO[B]THIOPHENE-2-BORONIC ACID
Authors:Shoichet, B.K., Thomas, V.L.
Deposit date:2009-09-03
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural bases for stability-function tradeoffs in antibiotic resistance.
J.Mol.Biol., 396, 2010
3IXD
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X-RAY CRYSTAL STRUCTURE OF THE EXTENDED-SPECTRUM AMPC V298E MUTANT BETA-LACTAMASE AT 2.64 ANGSTROM RESOLUTION
Descriptor:Beta-lactamase, SULFATE ION
Authors:Shoichet, B.K., Thomas, V.L.
Deposit date:2009-09-03
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural bases for stability-function tradeoffs in antibiotic resistance.
J.Mol.Biol., 396, 2010
3IXG
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X-RAY CRYSTAL STRUCTURE OF THE EXTENDED-SPECTRUM AMPC T70I MUTANT BETA-LACTAMASE WITH AND WITHOUT BENZO(B)THIOPHENE-2-BORONIC ACID BOUND AT 2.14 ANGSTROM RESOLUTION
Descriptor:Beta-lactamase, BENZO[B]THIOPHENE-2-BORONIC ACID
Authors:Shoichet, B.K., Thomas, V.L.
Deposit date:2009-09-04
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural bases for stability-function tradeoffs in antibiotic resistance.
J.Mol.Biol., 396, 2010
3IXH
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X-RAY CRYSTAL STRUCTURE OF THE EXTENDED-SPECTRUM AMPC Y221G MUTANT BETA-LACTAMASE IN COMPLEX WITH CEFOTAXIME AT 2.3 ANGSTROM RESOLUTION
Descriptor:Beta-lactamase, CEFOTAXIME, C3' cleaved, ...
Authors:Shoichet, B.K., Thomas, V.L.
Deposit date:2009-09-04
Release date:2010-02-16
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural bases for stability-function tradeoffs in antibiotic resistance.
J.Mol.Biol., 396, 2010
3CMZ
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TEM-1 CLASS-A BETA-LACTAMASE L201P MUTANT APO STRUCTURE
Descriptor:Beta-lactamase TEM, PHOSPHATE ION
Authors:Marciano, D.C., Wang, X., Wang, J., Chen, Y., Thomas, V.L., Shoichet, B.K., Palzkill, T.
Deposit date:2008-03-24
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Genetic and structural characterization of an L201P global suppressor substitution in TEM-1 beta-lactamase
J.Mol.Biol., 384, 2008