1CTN | | CRYSTAL STRUCTURE OF A BACTERIAL CHITINASE AT 2.3 ANGSTROMS RESOLUTION | | Descriptor: | CHITINASE A | | Authors: | Perrakis, A., Tews, I., Dauter, Z., Wilson, K.S., Vorgias, C.E. | | Deposit date: | 1994-10-10 | | Release date: | 1995-02-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of a bacterial chitinase at 2.3 A resolution.
Structure, 2, 1994
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6QCG | |
1OH5 | | THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH A C:A MISMATCH | | Descriptor: | DNA MISMATCH REPAIR PROTEIN MUTS, 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*CP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP *CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*AP*TP*GP*GP *CP*AP*GP*CP*T)-3', ... | | Authors: | Natrajan, G., Lamers, M.H., Enzlin, J.H., Winterwerp, H.H.K., Perrakis, A., Sixma, T.K. | | Deposit date: | 2003-05-23 | | Release date: | 2003-08-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
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1OH6 | | THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH AN A:A MISMATCH | | Descriptor: | DNA MISMATCH REPAIR PROTEIN MUTS, 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*AP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP* CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*AP*TP*GP*GP* CP*AP*GP*CP*T)-3', ... | | Authors: | Natrajan, G., Lamers, M.H., Enzlin, J.H., Winterwerp, H.H.K., Perrakis, A., Sixma, T.K. | | Deposit date: | 2003-05-23 | | Release date: | 2003-08-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
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1OH7 | | THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH A G:G MISMATCH | | Descriptor: | DNA MISMATCH REPAIR PROTEIN MUTS, 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP *CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*GP*TP*GP*GP *CP*AP*GP*CP*T)-3', ... | | Authors: | Natrajan, G., Lamers, M.H., Enzlin, J.H., Winterwerp, H.H.K., Perrakis, A., Sixma, T.K. | | Deposit date: | 2003-05-23 | | Release date: | 2003-08-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
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1OH8 | | THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH AN UNPAIRED THYMIDINE | | Descriptor: | DNA MISMATCH REPAIR PROTEIN MUTS, 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP*CP*CP* TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*CP*TP*TP*GP*GP*CP* AP*GP*CP*T)-3', ... | | Authors: | Natrajan, G., Lamers, M.H., Enzlin, J.H., Winterwerp, H.H.K., Perrakis, A., Sixma, T.K. | | Deposit date: | 2003-05-23 | | Release date: | 2003-08-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
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2X4P | | CRYSTAL STRUCTURE OF MHC CLASS I HLA-A2.1 BOUND TO A PHOTOCLEAVABLE PEPTIDE | | Descriptor: | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2.1, BETA-2-MICROGLOBULIN, ... | | Authors: | Celie, P.H.N., Toebes, M., Rodenko, B., Ovaa, H., Perrakis, A., Schumacher, T.N.M. | | Deposit date: | 2010-02-02 | | Release date: | 2010-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger.
J.Am.Chem.Soc., 131, 2009
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2X4Q | | CRYSTAL STRUCTURE OF MHC CLASS I HLA-A2.1 BOUND TO A PHOTOCLEAVABLE PEPTIDE | | Descriptor: | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2.1, BETA-2-MICROGLOBULIN, ... | | Authors: | Celie, P.H.N., Toebes, M., Rodenko, B., Ovaa, H., Perrakis, A., Schumacher, T.N.M. | | Deposit date: | 2010-02-02 | | Release date: | 2010-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger.
J.Am.Chem.Soc., 131, 2009
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2X4T | | CRYSTAL STRUCTURE OF MHC CLASS I HLA-A2.1 BOUND TO A PEIODATE- CLEAVABLE PEPTIDE | | Descriptor: | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2.1, BETA-2-MICROGLOBULIN, ... | | Authors: | Rodenko, B., Toebes, M., Celie, P.H.N., Perrakis, A., Schumacher, T.N.M., Ovaa, H. | | Deposit date: | 2010-02-02 | | Release date: | 2010-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger.
J.Am.Chem.Soc., 131, 2009
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2XR9 | | CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2) | | Descriptor: | ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... | | Authors: | Kamtekar, S., Hausmann, J., Day, J.E., Christodoulou, E., Perrakis, A. | | Deposit date: | 2010-09-13 | | Release date: | 2011-01-19 | | Last modified: | 2018-02-28 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis of substrate discrimination and integrin binding by autotaxin.
Nat. Struct. Mol. Biol., 18, 2011
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2W8F | | APLYSIA CALIFORNICA ACHBP BOUND TO IN SILICO COMPOUND 31 | | Descriptor: | SOLUBLE ACETYLCHOLINE RECEPTOR, (3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANE | | Authors: | Ulens, C., Akdemir, A., Jongejan, A., van Elk, R., Edink, E., Bertrand, S., Perrakis, A., Leurs, R., Smit, A.B., Sixma, T.K., Bertrand, D., de Esch, I.J. | | Deposit date: | 2009-01-16 | | Release date: | 2009-04-14 | | Last modified: | 2011-09-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Use of Acetylcholine Binding Protein in the Search for Novel Alpha7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X- Ray Analysis.
J.Med.Chem., 52, 2009
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2W8G | | APLYSIA CALIFORNICA ACHBP BOUND TO IN SILICO COMPOUND 35 | | Descriptor: | SOLUBLE ACETYLCHOLINE RECEPTOR, (3-ENDO,8-ANTI)-8-BENZYL-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8-AZONIABICYCLO[3.2.1]OCTANE | | Authors: | Ulens, C., Akdemir, A., Jongejan, A., van Elk, R., Edink, E., Bertrand, S., Perrakis, A., Leurs, R., Smit, A.B., Sixma, T.K., Bertrand, D., de Esch, I.J. | | Deposit date: | 2009-01-16 | | Release date: | 2009-04-14 | | Last modified: | 2015-03-18 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Use of Acetylcholine Binding Protein in the Search for Novel Alpha7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X- Ray Analysis.
J.Med.Chem., 52, 2009
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2Y7Y | | APLYSIA CALIFORNICA ACHBP IN APO STATE | | Descriptor: | SOLUBLE ACETYLCHOLINE RECEPTOR | | Authors: | Ulens, C., Akdemir, A., Jongejan, A., van Elk, R., Bertrand, S., Perrakis, A., Leurs, R., Smit, A.B., Sixma, T.K., Bertrand, D., De Esch, I.J. | | Deposit date: | 2011-02-02 | | Release date: | 2011-03-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.895 Å) | | Cite: | Use of Acetylcholine Binding Protein in the Search for Novel Alpha7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-Ray Analysis.
J.Med.Chem., 52, 2009
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1DCS | | DEACETOXYCEPHALOSPORIN C SYNTHASE FROM S. CLAVULIGERUS | | Descriptor: | DEACETOXYCEPHALOSPORIN C SYNTHASE, SULFATE ION | | Authors: | Valegard, K., Terwisscha Van Scheltinga, A.C., Lloyd, M.D., Hara, T., Ramaswamy, S., Perrakis, A., Thompson, A., Lee, H.J., Baldwin, J.E., Schofield, C.J., Hajdu, J., Andersson, I. | | Deposit date: | 1998-06-05 | | Release date: | 1999-06-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structure of a cephalosporin synthase.
Nature, 394, 1998
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1DW9 | | STRUCTURE OF CYANASE REVEALS THAT A NOVEL DIMERIC AND DECAMERIC ARRANGEMENT OF SUBUNITS IS REQUIRED FOR FORMATION OF THE ENZYME ACTIVE SITE | | Descriptor: | CYANATE LYASE, CHLORIDE ION, SULFATE ION | | Authors: | Walsh, M.A., Otwinowski, Z., Perrakis, A., Anderson, P.M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 1999-12-03 | | Release date: | 2000-05-16 | | Last modified: | 2011-09-28 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of Cyanase Reveals that a Novel Dimeric and Decameric Arrangement of Subunits is Required for Formation of the Enzyme Active Site
Structure, 8, 2000
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1DWK | | STRUCTURE OF CYANASE WITH THE DI-ANION OXALATE BOUND AT THE ENZYME ACTIVE SITE | | Descriptor: | CYANATE HYDRATASE, SULFATE ION, OXALATE ION | | Authors: | Walsh, M.A., Otwinowski, Z., Perrakis, A., Anderson, P.M., Joachimiak, A. | | Deposit date: | 1999-12-07 | | Release date: | 2000-05-16 | | Last modified: | 2017-07-12 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of Cyanase Reveals that a Novel Dimeric and Decameric Arrangement of Subunits is Required for Formation of the Enzyme Active Site.
Structure, 8, 2000
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1EPU | | X-RAY CRYSTAL STRUCTURE OF NEURONAL SEC1 FROM SQUID | | Descriptor: | S-SEC1 | | Authors: | Bracher, A., Perrakis, A., Dresbach, T., Betz, H., Weissenhorn, W. | | Deposit date: | 2000-03-29 | | Release date: | 2000-08-09 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis.
Structure Fold.Des., 8, 2000
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1O9K | | CRYSTAL STRUCTURE OF THE RETINOBLASTOMA TUMOUR SUPPRESSOR PROTEIN BOUND TO E2F PEPTIDE | | Descriptor: | RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1 | | Authors: | Xiao, B., Spencer, J., Clements, A., Ali-Khan, N., Mittnacht, S., Broceno, C., Burghammer, M., Perrakis, A., Marmorstein, R., Gamblin, S.J. | | Deposit date: | 2002-12-16 | | Release date: | 2003-03-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
Proc.Natl.Acad.Sci.USA, 100, 2003
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1QBA | | BACTERIAL CHITOBIASE, GLYCOSYL HYDROLASE FAMILY 20 | | Descriptor: | CHITOBIASE, SULFATE ION | | Authors: | Tews, I., Perrakis, A., Oppenheim, A., Dauter, Z., Wilson, K.S., Vorgias, C.E. | | Deposit date: | 1996-06-06 | | Release date: | 1997-01-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease.
Nat.Struct.Biol., 3, 1996
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1QBB | | BACTERIAL CHITOBIASE COMPLEXED WITH CHITOBIOSE (DINAG) | | Descriptor: | CHITOBIASE, DI(N-ACETYL-D-GLUCOSAMINE), SULFATE ION | | Authors: | Tews, I., Perrakis, A., Oppenheim, A., Dauter, Z., Wilson, K.S., Vorgias, C.E. | | Deposit date: | 1996-06-07 | | Release date: | 1997-02-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease.
Nat.Struct.Biol., 3, 1996
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1RXF | | DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH FE(II) | | Descriptor: | DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (III) ION | | Authors: | Valegard, K., Terwisscha Van Scheltinga, A.C., Lloyd, M.D., Hara, T., Ramaswamy, S., Perrakis, A., Thompson, A., Lee, H.J., Baldwin, J.E., Schofield, C.J., Hajdu, J., Andersson, I. | | Deposit date: | 1998-06-05 | | Release date: | 1999-06-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of a cephalosporin synthase.
Nature, 394, 1998
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1RXG | | DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH FE(II) AND 2-OXOGLUTARATE | | Descriptor: | DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (III) ION, SULFATE ION, ... | | Authors: | Valegard, K., Terwisscha Van Scheltinga, A.C., Lloyd, M.D., Hara, T., Ramaswamy, S., Perrakis, A., Thompson, A., Lee, H.J., Baldwin, J.E., Shofield, C.J., Hajdu, J., Andersson, I. | | Deposit date: | 1998-06-05 | | Release date: | 1999-06-08 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of a cephalosporin synthase.
Nature, 394, 1998
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2KLS | | APO-FORM OF THE SECOND CA2+ BINDING DOMAIN OF NCX1.4 | | Descriptor: | Sodium/calcium exchanger 1 | | Authors: | Hilge, M., Aelen, J., Foarce, A., Perrakis, A., Vuister, G.W. | | Deposit date: | 2009-07-08 | | Release date: | 2009-08-18 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2KLT | | SECOND CA2+ BINDING DOMAIN OF NCX1.3 | | Descriptor: | Sodium/calcium exchanger 1 | | Authors: | Hilge, M., Aelen, J., Foarce, A., Perrakis, A., Vuister, G.W. | | Deposit date: | 2009-07-08 | | Release date: | 2009-08-18 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2WVR | | HUMAN CDT1:GEMININ COMPLEX | | Descriptor: | GEMININ, DNA REPLICATION FACTOR CDT1 | | Authors: | De Marco, V., Perrakis, A. | | Deposit date: | 2009-10-19 | | Release date: | 2009-10-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Quaternary Structure of the Human Cdt1-Geminin Complex Regulates DNA Replication Licensing.
Proc.Natl.Acad.Sci.USA, 106, 2009
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