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3U0X
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CRYSTAL STRUCTURE OF THE B-SPECIFIC-1,3-GALACTOSYLTRANSFERASE (GTB) IN COMPLEX WITH COMPOUND 382
Descriptor:Histo-blood group ABO system transferase, 1-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine, CHLORIDE ION, ...
Authors:Palcic, M.M., Jorgensen, R.
Deposit date:2011-09-29
Release date:2012-10-24
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A novel compound from a molecular fragment library screen inhibits glycosyltransferases by displacing the metal ion and interfering with substrate binding
To be Published
3U0Y
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CRYSTAL STRUCTURE OF THE FUCOSYLGALACTOSIDE ALPHA N-ACETYLGALACTOSAMINYLTRANSFERASE (GTA, CISAB MUTANT L266G, G268A) IN COMPLEX WITH COMPOUND 382 AND UDP
Descriptor:Histo-blood group ABO system transferase, 1-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine, URIDINE-5'-DIPHOSPHATE, ...
Authors:Palcic, M.M., Jorgensen, R.
Deposit date:2011-09-29
Release date:2012-10-24
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A novel compound from a molecular fragment library screen inhibits glycosyltransferases by displacing the metal ion and interfering with substrate binding
To be Published
3V0L
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CRYSTAL STRUCTURE OF THE FUCOSYLGALACTOSIDE ALPHA N-ACETYLGALACTOSAMINYLTRANSFERASE (GTA, CISAB MUTANT L266G, G268A) IN COMPLEX WITH A NOVEL UDP-GAL DERIVED INHIBITOR (2GW)
Descriptor:Histo-blood group ABO system transferase, MANGANESE (II) ION, 5-phenyl-uridine-5'-alpha-d-galactosyl-diphosphate, ...
Authors:Palcic, M.M., Jorgensen, R.
Deposit date:2011-12-08
Release date:2013-01-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase.
J.Biol.Chem., 288, 2013
3V0M
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CRYSTAL STRUCTURE OF THE FUCOSYLGALACTOSIDE ALPHA N-ACETYLGALACTOSAMINYLTRANSFERASE (GTA, CISAB MUTANT L266G, G268A) IN COMPLEX WITH A NOVEL UDP-GAL DERIVED INHIBITOR (5GW) AND H-ANTIGEN ACCEPTOR
Descriptor:Histo-blood group ABO system transferase, MANGANESE (II) ION, 5-phenyluridine 5'-(trihydrogen diphosphate), ...
Authors:Palcic, M.M., Jorgensen, R.
Deposit date:2011-12-08
Release date:2013-01-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase.
J.Biol.Chem., 288, 2013
3V0N
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CRYSTAL STRUCTURE OF THE FUCOSYLGALACTOSIDE ALPHA N-ACETYLGALACTOSAMINYLTRANSFERASE (GTA, CISAB MUTANT L266G, G268A) IN COMPLEX WITH A NOVEL UDP-GALNAC DERIVED INHIBITOR (3GW AND 4GW)
Descriptor:Histo-blood group ABO system transferase, MANGANESE (II) ION, 5-(5-formylthiophen-2-yl)uridine 5'-(trihydrogen diphosphate), ...
Authors:Palcic, M.M., Jorgensen, R.
Deposit date:2011-12-08
Release date:2013-01-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Base-modified donor analogues reveal novel dynamic features of a glycosyltransferase.
J.Biol.Chem., 288, 2013
3V0O
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CRYSTAL STRUCTURE OF THE FUCOSYLGALACTOSIDE ALPHA N-ACETYLGALACTOSAMINYLTRANSFERASE (GTA, CISAB MUTANT L266G, G268A) IN COMPLEX WITH A NOVEL UDP-GALNAC DERIVED INHIBITOR (4GW) AND H-ANTIGEN ACCEPTOR
Descriptor:Histo-blood group ABO system transferase, MANGANESE (II) ION, 5-(5-formylthiophen-2-yl)uridine 5'-(trihydrogen diphosphate), ...
Authors:Palcic, M.M., Jorgensen, R.
Deposit date:2011-12-08
Release date:2013-01-23
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Base-modified donor analogues reveal novel dynamic features of a glycosyltransferase.
J.Biol.Chem., 288, 2013
3V0P
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CRYSTAL STRUCTURE OF THE FUCOSYLGALACTOSIDE ALPHA N-ACETYLGALACTOSAMINYLTRANSFERASE (GTA, CISAB MUTANT L266G, G268A) IN COMPLEX WITH A NOVEL UDP-GAL DERIVED INHIBITOR (4GW) AND H-ANTIGEN ACCEPTOR
Descriptor:Histo-blood group ABO system transferase, MANGANESE (II) ION, 5-(5-formylthiophen-2-yl)uridine 5'-(trihydrogen diphosphate), ...
Authors:Palcic, M.M., Jorgensen, R.
Deposit date:2011-12-08
Release date:2013-01-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase.
J.Biol.Chem., 288, 2013
3V0Q
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CRYSTAL STRUCTURE OF THE FUCOSYLGALACTOSIDE ALPHA N-ACETYLGALACTOSAMINYLTRANSFERASE (GTA, CISAB MUTANT L266G, G268A) IN COMPLEX WITH UDP AND H-ANTIGEN ACCEPTOR
Descriptor:Histo-blood group ABO system transferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
Authors:Palcic, M.M., Jorgensen, R.
Deposit date:2011-12-08
Release date:2013-01-23
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase.
J.Biol.Chem., 288, 2013
2Y7A
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CRYSTAL STRUCTURE OF UNLIGANDED GTB P156L
Descriptor:ABO GLYCOSYLTRANSFERASE, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE
Authors:Weadge, J., Palcic, M.M., Henriksen, A.
Deposit date:2011-01-31
Release date:2012-02-15
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural and Biochemical Characterization of the Human Blood Group a and B Galactosyltransferases Possessing the Pro156Leu Mutation
To be Published
4HLN
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STRUCTURE OF BARLEY STARCH SYNTHASE I IN COMPLEX WITH MALTOOLIGOSACCHARIDE
Descriptor:Starch synthase I, ALPHA-D-GLUCOSE
Authors:Cuesta-Seijo, J.A., Nielsen, M.M., Marri, L., Tanaka, H., Palcic, M.M.
Deposit date:2012-10-17
Release date:2013-06-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of starch synthase I from barley: insight into regulatory mechanisms of starch synthase activity
Acta Crystallogr.,Sect.D, 69, 2013
6GNF
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GRANULE BOUND STARCH SYNTHASE FROM CYANOBACTERIUM SP. CLG1 BOUND TO ACARBOSE AND ADP
Descriptor:Glycogen synthase, ADENOSINE-5'-DIPHOSPHATE, BETA-ACARBOSE, ...
Authors:Cuesta-Seijo, J.A., Nielsen, M.M., Palcic, M.M.
Deposit date:2018-05-30
Release date:2018-07-25
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of theCatalyticDomain ofArabidopsis thalianaStarch Synthase IV, of Granule Bound Starch Synthase From CLg1 and of Granule Bound Starch Synthase I ofCyanophora paradoxaIllustrate Substrate Recognition in Starch Synthases.
Front Plant Sci, 9, 2018
6GNG
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GRANULE BOUND STARCH SYNTHASE I FROM CYANOPHORA PARADOXA BOUND TO ACARBOSE AND ADP
Descriptor:Granule-bound starch synthase, BETA-ACARBOSE, ADENOSINE-5'-DIPHOSPHATE
Authors:Cuesta-Seijo, J.A., Nielsen, M.M., Palcic, M.M.
Deposit date:2018-05-30
Release date:2018-07-25
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal Structures of theCatalyticDomain ofArabidopsis thalianaStarch Synthase IV, of Granule Bound Starch Synthase From CLg1 and of Granule Bound Starch Synthase I ofCyanophora paradoxaIllustrate Substrate Recognition in Starch Synthases.
Front Plant Sci, 9, 2018
6GNE
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CATALYTIC DOMAIN OF STARCH SYNTHASE IV FROM ARABIDOPSIS THALIANA BOUND TO ADP AND ACARBOSE
Descriptor:Probable starch synthase 4, chloroplastic/amyloplastic, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Cuesta-Seijo, J.A., Ruzanski, C., Krucewicz, K., Striebeck, A., Palcic, M.M.
Deposit date:2018-05-30
Release date:2018-07-25
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structures of theCatalyticDomain ofArabidopsis thalianaStarch Synthase IV, of Granule Bound Starch Synthase From CLg1 and of Granule Bound Starch Synthase I ofCyanophora paradoxaIllustrate Substrate Recognition in Starch Synthases.
Front Plant Sci, 9, 2018
1LZ0
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GLYCOSYLTRANSFERASE A
Descriptor:Glycosyltransferase A, MERCURY (II) ION
Authors:Patenaude, S.I., Seto, N.O.L., Borisova, S.N., Szpacenko, A., Marcus, S.L., Palcic, M.M., Evans, S.V.
Deposit date:2002-06-10
Release date:2002-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structural basis for specificity in human ABO(H) blood group biosynthesis.
Nat.Struct.Biol., 9, 2002
1LZ7
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GLYCOSYLTRANSFERASE B
Descriptor:Glycosyltransferase B, MERCURY (II) ION
Authors:Patenaude, S.I., Seto, N.O.L., Borisova, S.N., Szpacenko, A., Marcus, S.L., Palcic, M.M., Evans, S.V.
Deposit date:2002-06-10
Release date:2002-08-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The structural basis for specificity in human ABO(H) blood group biosynthesis.
Nat.Struct.Biol., 9, 2002
1LZI
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GLYCOSYLTRANSFERASE A + UDP + H ANTIGEN ACCEPTOR
Descriptor:Glycosyltransferase A, 2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL, ALPHA-L-FUCOSE, ...
Authors:Patenaude, S.I., Seto, N.O.L., Borisova, S.N., Szpacenko, A., Marcus, S.L., Palcic, M.M., Evans, S.V.
Deposit date:2002-06-10
Release date:2002-08-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The structural basis for specificity in human ABO(H) blood group biosynthesis.
Nat.Struct.Biol., 9, 2002
1LZJ
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GLYCOSYLTRANSFERASE B + UDP + H ANTIGEN ACCEPTOR
Descriptor:Glycosyltransferase B, 2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL, ALPHA-L-FUCOSE, ...
Authors:Patenaude, S.I., Seto, N.O.L., Borisova, S.N., Szpacenko, A., Marcus, S.L., Palcic, M.M., Evans, S.V.
Deposit date:2002-06-10
Release date:2002-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:The structural basis for specificity in human ABO(H) blood group biosynthesis.
Nat.Struct.Biol., 9, 2002
1R7T
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GLYCOSYLTRANSFERASE A IN COMPLEX WITH 3-DEOXY-ACCEPTOR ANALOG INHIBITOR
Descriptor:Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, HEXYL 3-DEOXY-BETA-D-GALACTOPYRANOSE, ALPHA-L-FUCOSE, ...
Authors:Nguyen, H.P., Seto, N.O.L., Cai, Y., Leinala, E.K., Borisova, S.N., Palcic, M.M., Evans, S.V.
Deposit date:2003-10-22
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
1R7U
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GLYCOSYLTRANSFERASE B IN COMPLEX WITH 3-DEOXY-ACCEPTOR ANALOG INHIBITOR
Descriptor:Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, HEXYL 3-DEOXY-BETA-D-GALACTOPYRANOSE, ALPHA-L-FUCOSE, ...
Authors:Nguyen, H.P., Seto, N.O.L., Cai, Y., Leinala, E.K., Borisova, S.N., Palcic, M.M., Evans, S.V.
Deposit date:2003-10-22
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
1R7V
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GLYCOSYLTRANSFERASE A IN COMPLEX WITH 3-AMINO-ACCEPTOR ANALOG INHIBITOR
Descriptor:Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, 4-AMINO-2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL, ALPHA-L-FUCOSE, ...
Authors:Nguyen, H.P., Seto, N.O.L., Cai, Y., Leinala, E.K., Borisova, S.N., Palcic, M.M., Evans, S.V.
Deposit date:2003-10-22
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
1R7X
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GLYCOSYLTRANSFERASE B IN COMPLEX WITH 3-AMINO-ACCEPTOR ANALOG INHIBITOR
Descriptor:Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, 4-AMINO-2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL, ALPHA-L-FUCOSE, ...
Authors:Nguyen, H.P., Seto, N.O.L., Cai, Y., Leinala, E.K., Borisova, S.N., Palcic, M.M., Evans, S.V.
Deposit date:2003-10-22
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
1R7Y
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GLYCOSYLTRANSFERASE A IN COMPLEX WITH 3-AMINO-ACCEPTOR ANALOG INHIBITOR AND URIDINE DIPHOSPHATE
Descriptor:Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, 4-AMINO-2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL, ALPHA-L-FUCOSE, ...
Authors:Nguyen, H.P., Seto, N.O.L., Cai, Y., Leinala, E.K., Borisova, S.N., Palcic, M.M., Evans, S.V.
Deposit date:2003-10-22
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
1R80
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GLYCOSYLTRANSFERASE B IN COMPLEX WITH 3-AMINO-ACCEPTOR ANALOG INHIBITOR AND URIDINE DIPHOSPHATE
Descriptor:Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, 4-AMINO-2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL, ALPHA-L-FUCOSE, ...
Authors:Nguyen, H.P., Seto, N.O.L., Cai, Y., Leinala, E.K., Borisova, S.N., Palcic, M.M., Evans, S.V.
Deposit date:2003-10-22
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
1R81
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GLYCOSYLTRANSFERASE A IN COMPLEX WITH 3-AMINO-ACCEPTOR ANALOG INHIBITOR AND URIDINE DIPHOSPHATE-N-ACETYL-GALACTOSE
Descriptor:Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, 4-AMINO-2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL, ALPHA-L-FUCOSE, ...
Authors:Nguyen, H.P., Seto, N.O.L., Cai, Y., Leinala, E.K., Borisova, S.N., Palcic, M.M., Evans, S.V.
Deposit date:2003-10-22
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
1R82
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GLYCOSYLTRANSFERASE B IN COMPLEX WITH 3-AMINO-ACCEPTOR ANALOG INHIBITOR, AND URIDINE DIPHOSPHATE-GALACTOSE
Descriptor:Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, 4-AMINO-2-OCTYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL, ALPHA-L-FUCOSE, ...
Authors:Nguyen, H.P., Seto, N.O.L., Cai, Y., Leinala, E.K., Borisova, S.N., Palcic, M.M., Evans, S.V.
Deposit date:2003-10-22
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003