Author results

2JJX
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THE CRYSTAL STRUCTURE OF UMP KINASE FROM BACILLUS ANTHRACIS (BA1797)
Descriptor:URIDYLATE KINASE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Meier, C., Carter, L.G., Mancini, E.J., Owens, R.J., Stuart, D.I., Esnouf, R.M., Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE)
Deposit date:2008-04-23
Release date:2008-07-29
Last modified:2017-05-24
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:The Crystal Structure of Ump Kinase from Bacillus Anthracis (Ba1797) Reveals an Allosteric Nucleotide-Binding Site.
J.Mol.Biol., 381, 2008
2VD9
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THE CRYSTAL STRUCTURE OF ALANINE RACEMASE FROM BACILLUS ANTHRACIS (BA0252) WITH BOUND L-ALA-P
Descriptor:ALANINE RACEMASE, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Au, K., Ren, J., Walter, T.S., Harlos, K., Nettleship, J.E., Owens, R.J., Stuart, D.I., Esnouf, R.M., Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE)
Deposit date:2007-10-01
Release date:2008-05-20
Last modified:2012-02-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of an Alanine Racemase from Bacillus Anthracis (Ba0252) in the Presence and Absence of (R)-1-Aminoethylphosphonic Acid (L-Ala-P).
Acta Crystallogr.,Sect.F, 64, 2008
3DGG
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CRYSTAL STRUCTURE OF FABOX108
Descriptor:FabOX108 Light Chain Fragment, FabOX108 Heavy Chain Fragment, MAGNESIUM ION
Authors:Ren, J., Nettleship, J.E., Owens, R.J., Oxford Protein Production Facility (OPPF)
Deposit date:2008-06-13
Release date:2008-08-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A pipeline for the production of antibody fragments for structural studies using transient expression in HEK 293T cells.
Protein Expr.Purif., 62, 2008
3DIF
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CRYSTAL STRUCTURE OF FABOX117
Descriptor:FabOX117 Light Chain Fragment, FabOX117 Heavy Chain Fragment
Authors:Nettleship, J.E., Ren, J., Owens, R.J., Oxford Protein Production Facility (OPPF)
Deposit date:2008-06-20
Release date:2008-08-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A pipeline for the production of antibody fragments for structural studies using transient expression in HEK 293T cells.
Protein Expr.Purif., 62, 2008
2P5V
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CRYSTAL STRUCTURE OF TRANSCRIPTIONAL REGULATOR NMB0573 FROM NEISSERIA MENINGITIDIS
Descriptor:Transcriptional regulator, LRP/AsnC family, CALCIUM ION, ...
Authors:Ren, J., Sainsbury, S., Owens, R.J., Oxford Protein Production Facility (OPPF)
Deposit date:2007-03-16
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The Structure and Transcriptional Analysis of a Global Regulator from Neisseria meningitidis.
J.Biol.Chem., 282, 2007
2P6S
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CRYSTAL STRUCTURE OF TRANSCRIPTIONAL REGULATOR NMB0573/L-MET COMPLEX FROM NEISSERIA MENINGITIDIS
Descriptor:Transcriptional regulator, LRP/AsnC family, METHIONINE, ...
Authors:Ren, J., Sainsbury, S., Owens, R.J., Oxford Protein Production Facility (OPPF)
Deposit date:2007-03-19
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure and Transcriptional Analysis of a Global Regulator from Neisseria meningitidis.
J.Biol.Chem., 282, 2007
2P6T
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CRYSTAL STRUCTURE OF TRANSCRIPTIONAL REGULATOR NMB0573 AND L-LEUCINE COMPLEX FROM NEISSERIA MENINGITIDIS
Descriptor:Transcriptional regulator, LRP/AsnC family, LEUCINE, ...
Authors:Ren, J., Sainsbury, S., Owens, R.J., Oxford Protein Production Facility (OPPF)
Deposit date:2007-03-19
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure and Transcriptional Analysis of a Global Regulator from Neisseria meningitidis.
J.Biol.Chem., 282, 2007
2VD8
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THE CRYSTAL STRUCTURE OF ALANINE RACEMASE FROM BACILLUS ANTHRACIS (BA0252)
Descriptor:ALANINE RACEMASE, PYRIDOXAL-5'-PHOSPHATE, MAGNESIUM ION, ...
Authors:Au, K., Ren, J., Walter, T.S., Harlos, K., Nettleship, J.E., Owens, R.J., Stuart, D.I., Esnouf, R.M., Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE)
Deposit date:2007-10-01
Release date:2008-05-20
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structures of an Alanine Racemase from Bacillus Anthracis (Ba0252) in the Presence and Absence of (R)-1-Aminoethylphosphonic Acid (L-Ala-P).
Acta Crystallogr.,Sect.F, 64, 2008
3G3Z
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THE STRUCTURE OF NMB1585, A MARR FAMILY REGULATOR FROM NEISSERIA MENINGITIDIS
Descriptor:Transcriptional regulator, MarR family
Authors:Nichols, C.E., Sainsbury, S., Ren, J., Walter, T.S., Verma, A., Stammers, D.K., Saunders, N.J., Owens, R.J., Oxford Protein Production Facility (OPPF)
Deposit date:2009-02-03
Release date:2009-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of NMB1585, a MarR-family regulator from Neisseria meningitidis
Acta Crystallogr.,Sect.F, 65, 2009
3HHF
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STRUCTURE OF CRGA REGULATORY DOMAIN, A LYSR-TYPE TRANSCRIPTIONAL REGULATOR FROM NEISSERIA MENINGITIDIS.
Descriptor:Transcriptional regulator, LysR family, CHLORIDE ION
Authors:Sainsbury, S., Ren, J., Owens, R.J., Stuart, D.I., Oxford Protein Production Facility (OPPF)
Deposit date:2009-05-15
Release date:2009-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators
Nucleic Acids Res., 37, 2009
3HHG
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STRUCTURE OF CRGA, A LYSR-TYPE TRANSCRIPTIONAL REGULATOR FROM NEISSERIA MENINGITIDIS.
Descriptor:Transcriptional regulator, LysR family
Authors:Sainsbury, S., Ren, J., Owens, R.J., Stuart, D.I., Oxford Protein Production Facility (OPPF)
Deposit date:2009-05-15
Release date:2009-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators
Nucleic Acids Res., 37, 2009
3JV9
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THE STRUCTURE OF A REDUCED FORM OF OXYR FROM N. MENINGITIDIS
Descriptor:Transcriptional regulator, LysR family, CHLORIDE ION
Authors:Sainsbury, S., Ren, J., Stuart, D.I., Owens, R.J., Oxford Protein Production Facility (OPPF)
Deposit date:2009-09-16
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:The structure of a reduced form of OxyR from Neisseria meningitidis
Bmc Struct.Biol., 10, 2010
4MCW
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METALLO-ENZYME FROM P. MARINA
Descriptor:Metal dependent phosphohydrolase, FE (III) ION, SUCCINIC ACID, ...
Authors:Bellini, D., Walsh, M.A., Oxford Protein Production Facility (OPPF)
Deposit date:2013-08-21
Release date:2014-02-19
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre.
Mol.Microbiol., 91, 2014
4MDZ
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METALLO-ENZYME FROM P. MARINA
Descriptor:Metal dependent phosphohydrolase, FE (III) ION, SUCCINIC ACID, ...
Authors:Bellini, D., Walsh, M.A., Oxford Protein Production Facility (OPPF)
Deposit date:2013-08-23
Release date:2014-02-19
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre.
Mol.Microbiol., 91, 2014
4ME4
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METALLO-ENZYME FROM P. MARINA
Descriptor:Metal dependent phosphohydrolase, FE (III) ION, SUCCINIC ACID, ...
Authors:Bellini, D., Walsh, M.A., Oxford Protein Production Facility (OPPF)
Deposit date:2013-08-24
Release date:2014-02-19
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre.
Mol.Microbiol., 91, 2014
2Q5H
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CRYSTAL STRUCTURE OF APO-WILDTYPE GLYCYL-TRNA SYNTHETASE
Descriptor:Glycyl-tRNA synthetase
Authors:Cader, M.Z., Ren, J., James, P.A., Bird, L.E., Talbot, K., Stammers, D.K., Oxford Protein Production Facility (OPPF)
Deposit date:2007-06-01
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy.
Febs Lett., 581, 2007
2Q5I
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CRYSTAL STRUCTURE OF APO S581L GLYCYL-TRNA SYNTHETASE MUTANT
Descriptor:Glycyl-tRNA synthetase, SULFATE ION
Authors:Cader, M.Z., Ren, J., James, P.A., Bird, L.E., Talbot, K., Stammers, D.K., Oxford Protein Production Facility (OPPF)
Deposit date:2007-06-01
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy.
Febs Lett., 581, 2007
3NAR
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CRYSTAL STRUCTURE OF ZHX1 HD4 (ZINC-FINGERS AND HOMEOBOXES PROTEIN 1, HOMEODOMAIN 4)
Descriptor:Zinc fingers and homeoboxes protein 1, SULFATE ION
Authors:Ren, J., Bird, L.E., Owens, R.J., Stammers, D.K., Oxford Protein Production Facility (OPPF)
Deposit date:2010-06-02
Release date:2010-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains
Bmc Struct.Biol., 10, 2010
4YU8
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CRYSTAL STRUCTURE OF NEUROBLASTOMA SUPPRESSOR OF TUMORIGENICITY 1
Descriptor:Neuroblastoma suppressor of tumorigenicity 1, GLYCEROL, N-ACETYL-D-GLUCOSAMINE
Authors:Ren, J., Nettleship, J.E., Stammers, D.K., Owens, R.J., Oxford Protein Production Facility (OPPF)
Deposit date:2015-03-18
Release date:2015-03-25
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Neuroblastoma suppressor of tumorigenicity 1
To Be Published
2A0J
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CRYSTAL STRUCTURE OF NITROGEN REGULATORY PROTEIN IIA-NTR FROM NEISSERIA MENINGITIDIS
Descriptor:PTS system, nitrogen regulatory IIA protein
Authors:Ren, J., Sainsbury, S., Berrow, N.S., Alderton, D., Nettleship, J.E., Stammers, D.K., Saunders, N.J., Owens, R.J., Oxford Protein Production Facility (OPPF)
Deposit date:2005-06-16
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of nitrogen regulatory protein IIANtr from Neisseria meningitidis
Bmc Struct.Biol., 5, 2005
2GW8
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STRUCTURE OF THE PII SIGNAL TRANSDUCTION PROTEIN OF NEISSERIA MENINGITIDIS AT 1.85 RESOLUTION
Descriptor:PII signal transduction protein
Authors:Nichols, C.E., Sainsbury, S., Berrow, N.S., Alderton, D., Stammers, D.K., Owens, R.J., Oxford Protein Production Facility (OPPF)
Deposit date:2006-05-04
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of the P(II) signal transduction protein of Neisseria meningitidis at 1.85 A resolution.
Acta Crystallogr.,Sect.F, 62, 2006
2PX2
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CRYSTAL STRUCTURE OF THE MURRAY VALLEY ENCEPHALITIS VIRUS NS5 2'-O METHYLTRANSFERASE DOMAIN IN COMPLEX WITH SAH (MONOCLINIC FORM 1)
Descriptor:Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Assenberg, R., Ren, J., Verma, A., Walter, T.S., Alderton, D., Hurrelbrink, R.J., Fuller, S.D., Owens, R.J., Stuart, D.I., Grimes, J.M., Oxford Protein Production Facility (OPPF)
Deposit date:2007-05-14
Release date:2007-05-29
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2PX4
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CRYSTAL STRUCTURE OF THE MURRAY VALLEY ENCEPHALITIS VIRUS NS5 2'-O METHYLTRANSFERASE DOMAIN IN COMPLEX WITH SAH (MONOCLINIC FORM 2)
Descriptor:Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], CHLORIDE ION, SULFATE ION, ...
Authors:Assenberg, R., Ren, J., Verma, A., Walter, T.S., Alderton, D., Hurrelbrink, R.J., Fuller, S.D., Owens, R.J., Stuart, D.I., Grimes, J.M., Oxford Protein Production Facility (OPPF)
Deposit date:2007-05-14
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2PX5
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CRYSTAL STRUCTURE OF THE MURRAY VALLEY ENCEPHALITIS VIRUS NS5 2'-O METHYLTRANSFERASE DOMAIN IN COMPLEX WITH SAH (ORTHORHOMBIC CRYSTAL FORM)
Descriptor:Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Assenberg, R., Ren, J., Verma, A., Walter, T.S., Alderton, D., Hurrelbrink, R.J., Fuller, S.D., Owens, R.J., Stuart, D.I., Grimes, J.M., Oxford Protein Production Facility (OPPF)
Deposit date:2007-05-14
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2PX8
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CRYSTAL STRUCTURE OF THE MURRAY VALLEY ENCEPHALITIS VIRUS NS5 2'-O METHYLTRANSFERASE DOMAIN IN COMPLEX WITH SAH AND 7M-GTP
Descriptor:Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, TRIPHOSPHATE, ...
Authors:Assenberg, R., Ren, J., Verma, A., Walter, T.S., Alderton, D., Hurrelbrink, R.J., Fuller, S.D., Owens, R.J., Stuart, D.I., Grimes, J.M., Oxford Protein Production Facility (OPPF)
Deposit date:2007-05-14
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
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