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1ETU
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STRUCTURAL DETAILS OF THE BINDING OF GUANOSINE DIPHOSPHATE TO ELONGATION FACTOR TU FROM E. COLI AS STUDIED BY X-RAY CRYSTALLOGRAPHY
Descriptor:ELONGATION FACTOR TU, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Clark, B.F.C., Lacour, T.F.M., Kjeldgaard, M., Morikawa, K., Nyborg, J., Rubin, R., Thirup, S.
Deposit date:1988-01-15
Release date:1988-07-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography.
EMBO J., 4, 1985
1TUI
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INTACT ELONGATION FACTOR TU IN COMPLEX WITH GDP
Descriptor:ELONGATION FACTOR TU, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Polekhina, G., Thirup, S., Kjeldgaard, M., Nissen, P., Lippmann, C., Nyborg, J.
Deposit date:1996-05-23
Release date:1997-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Helix unwinding in the effector region of elongation factor EF-Tu-GDP.
Structure, 4, 1996
1TTT
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PHE-TRNA, ELONGATION FACTOR EF-TU:GDPNP TERNARY COMPLEX
Descriptor:TRANSFER RIBONUCLEIC ACID (YEAST, PHE), OF ELONGATION FACTOR TU (EF-TU), ...
Authors:Nissen, P., Kjeldgaard, M., Thirup, S., Polekhina, G., Reshetnikova, L., Clark, B.F.C., Nyborg, J.
Deposit date:1995-11-16
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog.
Science, 270, 1995
2PSR
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HUMAN PSORIASIN (S100A7) CA2+ AND ZN2+ BOUND FORM (CRYSTAL FORM II)
Descriptor:PSORIASIN, CALCIUM ION, ZINC ION
Authors:Brodersen, D.E., Nyborg, J., Kjeldgaard, M.
Deposit date:1998-09-17
Release date:1999-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+-free states.
Biochemistry, 38, 1999
3PSR
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HUMAN PSORIASIN (S100A7) CA2+ BOUND FORM (CRYSTAL FORM I)
Descriptor:PSORIASIN, CALCIUM ION, ZINC ION
Authors:Brodersen, D.E., Nyborg, J., Kjeldgaard, M.
Deposit date:1998-09-17
Release date:1999-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+-free states.
Biochemistry, 38, 1999
1PSR
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HUMAN PSORIASIN (S100A7)
Descriptor:PSORIASIN, HOLMIUM ATOM
Authors:Brodersen, D.E., Etzerodt, M., Madsen, P., Celis, J., Thoegersen, H.C., Nyborg, J., Kjeldgaard, M.
Deposit date:1997-11-27
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing.
Structure, 6, 1998
1B23
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E. COLI CYSTEINYL-TRNA AND T. AQUATICUS ELONGATION FACTOR EF-TU:GTP TERNARY COMPLEX
Descriptor:CYSTEINYL TRNA, ELONGATION FACTOR TU, MAGNESIUM ION, ...
Authors:Nissen, P., Kjeldgaard, M., Thirup, S., Nyborg, J.
Deposit date:1998-12-04
Release date:1998-12-07
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals general and specific features in the ternary complex and in tRNA.
Structure Fold.Des., 7, 1999
1D2E
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CRYSTAL STRUCTURE OF MITOCHONDRIAL EF-TU IN COMPLEX WITH GDP
Descriptor:ELONGATION FACTOR TU (EF-TU), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Andersen, G.R., Thirup, S., Spremulli, L.L., Nyborg, J.
Deposit date:1999-09-23
Release date:1999-09-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:High resolution crystal structure of bovine mitochondrial EF-Tu in complex with GDP.
J.Mol.Biol., 297, 2000
1G7C
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YEAST EEF1A:EEF1BA IN COMPLEX WITH GDPNP
Descriptor:ELONGATION FACTOR 1-ALPHA, ELONGATION FACTOR 1-BETA, GUANOSINE-5'-MONOPHOSPHATE
Authors:Andersen, G.R., Valente, L., Pedersen, L., Kinzy, T.G., Nyborg, J.
Deposit date:2000-11-10
Release date:2000-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1IJE
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NUCLEOTIDE EXCHANGE INTERMEDIATES IN THE EEF1A-EEF1BA COMPLEX
Descriptor:elongation factor 1-alpha, elongation factor 1-beta, GUANOSINE-5'-DIPHOSPHATE
Authors:Andersen, G.R., Valente, L., Pedersen, L., Kinzy, T.G., Nyborg, J.
Deposit date:2001-04-26
Release date:2001-05-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1IJF
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NUCLEOTIDE EXCHANGE MECHANISMS IN THE EEF1A-EEF1BA COMPLEX
Descriptor:elongation factor 1-alpha, elongation factor 1-beta, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Andersen, G.R., Valente, L., Pedersen, L., Kinzy, T.G., Nyborg, J.
Deposit date:2001-04-26
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1WLE
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CRYSTAL STRUCTURE OF MAMMALIAN MITOCHONDRIAL SERYL-TRNA SYNTHETASE COMPLEXED WITH SERYL-ADENYLATE
Descriptor:Seryl-tRNA synthetase, SERYL ADENYLATE
Authors:Chimnaronk, S., Jeppesen, M.G., Suzuki, T., Nyborg, J., Watanabe, K.
Deposit date:2004-06-25
Release date:2005-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Dual-mode recognition of noncanonical tRNAs(Ser) by seryl-tRNA synthetase in mammalian mitochondria
Embo J., 24, 2005
1F60
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CRYSTAL STRUCTURE OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
Descriptor:ELONGATION FACTOR EEF1A, ELONGATION FACTOR EEF1BA
Authors:Andersen, G.R., Pedersen, L., Valente, L., Kinzy, T.G., Nyborg, J.
Deposit date:2000-06-19
Release date:2000-07-04
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha.
Mol.Cell, 6, 2000
1AYO
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RECEPTOR BINDING DOMAIN OF BOVINE ALPHA-2-MACROGLOBULIN
Descriptor:ALPHA-2-MACROGLOBULIN, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
Authors:Jenner, L.B., Husted, L., Thirup, S., Sottrup-Jensen, L., Nyborg, J.
Deposit date:1997-11-07
Release date:1998-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the receptor-binding domain of alpha 2-macroglobulin.
Structure, 6, 1998
1DXI
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STRUCTURE DETERMINATION OF GLUCOSE ISOMERASE FROM STREPTOMYCES MURINUS AT 2.6 ANGSTROMS RESOLUTION
Descriptor:D-XYLOSE ISOMERASE, MAGNESIUM ION
Authors:Rasmussen, H., La Cour, T., Nyborg, J., Schulein, M.
Deposit date:1993-09-30
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure determination of glucose isomerase from Streptomyces murinus at 2.6 A resolution.
Acta Crystallogr.,Sect.D, 50, 1994
1EFT
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THE CRYSTAL STRUCTURE OF ELONGATION FACTOR EF-TU FROM THERMUS AQUATICUS IN THE GTP CONFORMATION
Descriptor:ELONGATION FACTOR TU, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Kjeldgaard, M., Nissen, P., Thirup, S., Nyborg, J.
Deposit date:1993-08-24
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation.
Structure, 1, 1993
1NHY
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CRYSTAL STRUCTURE OF THE GST-LIKE DOMAIN OF ELONGATION FACTOR 1-GAMMA FROM SACCHAROMYCES CEREVISIAE.
Descriptor:Elongation factor 1-gamma 1, SULFATE ION
Authors:Jeppesen, M.G., Ortiz, P., Kinzy, T.G., Andersen, G.R., Nyborg, J.
Deposit date:2002-12-20
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Crystal Structure of the Glutathione S-Transferase-like Domain of Elongation Factor 1B{gamma} from Saccharomyces cerevisiae.
J.Biol.Chem., 278, 2003
1OB5
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T. AQUATICUS ELONGATION FACTOR EF-TU COMPLEXED WITH THE ANTIBIOTIC ENACYLOXIN IIA, A GTP ANALOG, AND PHE-TRNA
Descriptor:ELONGATION FACTOR TU, TRANSFER-RNA, PHE, ...
Authors:Dahlberg, C., Nielsen, R.C., Parmeggiani, A., Nyborg, J., Nissen, P.
Deposit date:2003-01-24
Release date:2005-10-13
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics.
J.Biol.Chem., 281, 2006
1XB2
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CRYSTAL STRUCTURE OF BOS TAURUS MITOCHONDRIAL ELONGATION FACTOR TU/TS COMPLEX
Descriptor:Elongation factor Tu, mitochondrial, Elongation factor Ts
Authors:Jeppesen, M.G., Navratil, T., Spremulli, L.L., Nyborg, J.
Deposit date:2004-08-27
Release date:2004-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the Bovine Mitochondrial Elongation Factor Tu.Ts Complex
J.Biol.Chem., 280, 2005
2B39
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STRUCTURE OF MAMMALIAN C3 WITH AN INTACT THIOESTER AT 3A RESOLUTION
Descriptor:C3, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Fredslund, F., Jenner, L., Husted, L.B., Nyborg, J., Andersen, G.R., Sottrup-Jensen, L.
Deposit date:2005-09-20
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of bovine complement component 3 reveals the basis for thioester function.
J.Mol.Biol., 361, 2006
2BVN
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E. COLI EF-TU:GDPNP IN COMPLEX WITH THE ANTIBIOTIC ENACYLOXIN IIA
Descriptor:ELONGATION FACTOR TU, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Parmeggiani, A., Krab, I.M., Watanabe, T., Nielsen, R.C., Dahlberg, C., Nyborg, J., Nissen, P.
Deposit date:2005-06-30
Release date:2005-09-01
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics.
J.Biol.Chem., 281, 2006
2C77
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EF-TU COMPLEXED WITH A GTP ANALOG AND THE ANTIBIOTIC GE2270 A
Descriptor:ELONGATION FACTOR TU-B, THIOCILLIN GE2270, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Parmeggiani, A., Krab, I.M., Okamura, S., Nielsen, R.C., Nyborg, J., Nissen, P.
Deposit date:2005-11-18
Release date:2006-03-16
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
2C78
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EF-TU COMPLEXED WITH A GTP ANALOG AND THE ANTIBIOTIC PULVOMYCIN
Descriptor:ELONGATION FACTOR TU-A, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Parmeggiani, A., Krab, I.M., Okamura, S., Nielsen, R.C., Nyborg, J., Nissen, P.
Deposit date:2005-11-18
Release date:2006-03-16
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
1EFC
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INTACT ELONGATION FACTOR FROM E.COLI
Descriptor:PROTEIN (ELONGATION FACTOR), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Song, H., Parsons, M.R., Rowsell, S., Leonard, G., Phillips, S.E.V.
Deposit date:1998-11-24
Release date:1999-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of intact elongation factor EF-Tu from Escherichia coli in GDP conformation at 2.05 A resolution.
J.Mol.Biol., 285, 1999
1LS2
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FITTING OF EF-TU AND TRNA IN THE LOW RESOLUTION CRYO-EM MAP OF AN EF-TU TERNARY COMPLEX (GDP AND KIRROMYCIN) BOUND TO E. COLI 70S RIBOSOME
Descriptor:Phenylalanine transfer RNA, Elongation Factor Tu
Authors:Valle, M., Sengupta, J., Swami, N.K., Grassucci, R.A., Burkhardt, N., Nierhaus, K.H., Agrawal, R.K., Frank, J.
Deposit date:2002-05-16
Release date:2002-06-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
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