Author results

6NTR
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CRYSTAL STRUCTURE OF BETA-BARREL-LIKE PROTEIN OF DOMAIN OF UNKNOWN FUNCTION DUF1849 FROM BRUCELLA ABORTUS
Descriptor:ATP/GTP-binding site-containing protein A, GLYCEROL, 1,2-ETHANEDIOL
Authors:Kim, Y., Bigelow, L., Endres, M., Babnigg, G., Crosson, S., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2019-01-30
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Crystal Structure of Beta-barrel-like Protein of Domain of Unknown Function DUF1849 from Brucella abortus
To Be Published
6NJC
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CRYSTAL STRUCTURE OF THE SIALATE O-ACETYLESTERASE FROM BACTEROIDES VULGATUS
Descriptor:Sialate O-acetylesterase, GLYCEROL, ACETIC ACID, ...
Authors:Kim, Y., Li, H., Biglow, L., Jedrzejczak, R., Babnigg, G., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2019-01-03
Release date:2019-01-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Sialate O-acetylesterase from Bacteroides vulgatus
To Be Published
6MR3
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CRYSTAL STRUCTURE OF THE COMPETENCE-DAMAGED PROTEIN (CINA) SUPERFAMILY PROTEIN FROM STREPTOCOCCUS MUTANS
Descriptor:Putative competence-damage inducible protein, CHLORIDE ION
Authors:Stogios, P.J., Cuff, M., Xu, X., Cui, H., Di Leo, R., Yim, V., Chin, S., Joachimiak, A.J., Midwest Center for Structural Genomics (MCSG)
Deposit date:2018-10-11
Release date:2018-10-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of the competence-damaged protein (CinA) superfamily protein from Streptococcus mutans
To Be Published
6HCD
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STRUCTURE OF UNIVERSAL STRESS PROTEIN FROM ARCHAEOGLOBUS FULGIDUS
Descriptor:UNIVERSAL STRESS PROTEIN, UNKNOWN LIGAND, CHLORIDE ION, ...
Authors:Shumilin, I.A., Loch, J.I., Cymborowski, M., Xu, X., Edwards, A., Di Leo, R., Shabalin, I.G., Joachimiak, A., Savchenko, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
Deposit date:2018-08-14
Release date:2018-08-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional insight into the universal stress protein family.
Evol Appl, 6, 2013
6DM4
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CRYSTAL STRUCTURE OF THE SH2 DOMAIN FROM RAVO (LPG1129) FROM LEGIONELLA PNEUMOPHILA IN COMPLEX WITH HOMO SAPIENS SHC1 PHOSPHO-TYR317 PEPTIDE
Descriptor:RavO, Shc1 phospho-Tyr317 peptide, SULFATE ION
Authors:Stogios, P.J., Evdokimova, E., Di Leo, R., Kaneko, T., Li, S., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2018-06-04
Release date:2018-06-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the SH2 domain from RavO (Lpg1129) from Legionella pneumophila in complex with Homo sapiens Shc1 phospho-Tyr317 peptide
To Be Published
6DM3
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CRYSTAL STRUCTURE OF THE SH2 DOMAIN FROM RAVO (LPG1129) FROM LEGIONELLA PNEUMOPHILA, APOPROTEIN
Descriptor:RavO
Authors:Stogios, P.J., Evdokimova, E., Di Leo, R., Kaneko, T., Li, S., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2018-06-04
Release date:2018-06-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the SH2 domain from RavO (Lpg1129) from Legionella pneumophila, apoprotein
To Be Published
6CP9
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CONTACT-DEPENDENT GROWTH INHIBITION TOXIN - IMMUNITY PROTEIN COMPLEX FROM KLEBSIELLA PNEUMONIAE 342
Descriptor:CdiA, CdiI
Authors:Michalska, K., Stols, L., Eschenfeldt, W., Hayes, C.S., Goulding, C.W., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2018-03-13
Release date:2019-03-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Contact-dependent growth inhibition toxin - immunity protein complex from Klebsiella pneumoniae 342
To Be Published
6CP8
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CONTACT-DEPENDENT GROWTH INHIBITION TOXIN-IMMUNITY PROTEIN COMPLEX FROM FROM E. COLI 3006
Descriptor:CdiA, CdiI, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Michalska, K., Stols, L., Eschenfeldt, W., Hayes, C.S., Goulding, C.W., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2018-03-13
Release date:2019-03-13
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006
To Be Published
6C9X
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THE CRYSTAL STRUCTURE OF THE ALPHA-GLUCOSIDASE (GH 31) FROM RUMINOCOCCUS OBEUM ATCC 29174 IN COMPLEX WITH VOGLIBOSE
Descriptor:Glycosyl hydrolase, family 31, (1S,2S,3R,4S,5S)-5-[(1,3-dihydroxypropan-2-yl)amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, ...
Authors:Tan, K., Tesar, C., Jedrzejczak, R., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2018-01-29
Release date:2018-03-07
Method:X-RAY DIFFRACTION (1.457 Å)
Cite:THE CRYSTAL STRUCTURE OF THE alpha-Glucosidase (GH 31) FROM RUMINOCOCCUS OBEUM ATCC 29174 in complex with voglibose
To Be Published
6BBX
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CRYSTAL STRUCTURE OF TNMS3 IN COMPLEX WITH TNM C
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2R,3R)-2,3-dihydroxy-3-[(1aS,11S,11aR,14Z,18R)-3,7,8,18-tetrahydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]butanoate
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-10-19
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
6B6L
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THE CRYSTAL STRUCTURE OF GLYCOSYL HYDROLASE FAMILY 2 (GH2) MEMBER FROM BACTEROIDES CELLULOSILYTICUS DSM 14838
Descriptor:Glycosyl hydrolase family 2, sugar binding domain protein, 1,2-ETHANEDIOL, ...
Authors:Tan, K., Joachimiak, G., Nocek, B., Enddres, M., Babnigg, G., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-10-02
Release date:2017-10-11
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838
To Be Published
6AZY
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CRYSTAL STRUCTURE OF HSP104 R328M/R757M MUTANT FROM CALCARISPORIELLA THERMOPHILA
Descriptor:Heat shock protein Hsp104, ADENOSINE-5'-DIPHOSPHATE
Authors:Michalska, K., Bigelow, L., Hatzos-Skintges, C., Jedrzejczak, R., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-09-13
Release date:2018-10-03
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of Hsp104 R328M/R757M mutant from Calcarisporiella thermophila
To Be Published
5WHM
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CRYSTAL STRUCTURE OF ICLR FAMILY TRANSCRIPTIONAL REGULATOR FROM BRUCELLA ABORTUS
Descriptor:IclR family transcriptional regulator, ACETIC ACID, CALCIUM ION, ...
Authors:Kim, Y., Wu, R., Tesar, C., Endres, M., Babnigg, G., Crosson, S., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-07-17
Release date:2017-08-23
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular control of gene expression byBrucellaBaaR, an IclR-type transcriptional repressor.
J. Biol. Chem., 293, 2018
5W27
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CRYSTAL STRUCTURE OF TNMS3 IN COMPLEX WITH TIANCIMYCIN (TNM B)
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2E)-3-[(1aS,11S,11aS,14Z,18R)-3,18-dihydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]but-2-enoate
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., SHen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-06-05
Release date:2018-06-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of TnmS3 in complex with tiancimycin (TNM B)
To Be Published
5VYM
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CRYSTAL STRUCTURE OF BETA-GALACTOSIDASE FROM BIFIDOBACTERIUM ADOLESCENTIS
Descriptor:Beta-galactosidase BgaB
Authors:Chang, C., Cuff, M., Tesar, C., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-05-25
Release date:2017-08-02
Method:X-RAY DIFFRACTION (2.456 Å)
Cite:Crystal structure of beta-galactosidase from Bifidobacterium adolescentis
To Be Published
5VVI
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CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF LYSR-TYPE TRANSCRIPTIONAL REGULATOR, OCCR FROM AGROBACTERIUM TUMEFACIENS IN THE COMPLEX WITH OCTOPINE
Descriptor:Octopine catabolism/uptake operon regulatory protein OccR, octopine, 1,2-ETHANEDIOL, ...
Authors:Kim, Y., Chhor, G., Jedrzejczak, R., Winans, S.C., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-05-19
Release date:2017-06-21
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal Structure of the Ligand-Binding Domain of a LysR-type Transcriptional Regulator: Transcriptional Activation via a Rotary Switch.
Mol. Microbiol., 2018
5VVH
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CRYSTAL STRUCTURE OF THE EFFECTOR BINDING DOMAIN OF LYSR-TYPE TRANSCRIPTIONAL REGULATOR, OCCR FROM AGROBACTERIUM TUMEFACIENS
Descriptor:Octopine catabolism/uptake operon regulatory protein OccR, SULFATE ION, FORMIC ACID
Authors:Kim, Y., Chhor, G., Jedrzejczak, R., Winans, S.C., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-05-19
Release date:2017-06-21
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Ligand-Binding Domain of a LysR-type Transcriptional Regulator: Transcriptional Activation via a Rotary Switch.
Mol. Microbiol., 2018
5VUG
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CRYSTAL STRUCTURE OF GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE DOMAIN OF UNCHARACTERIZED PROTEIN RV2277C FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Uncharacterized protein Rv2277c, CALCIUM ION, GLYCEROL
Authors:Kim, Y., Li, H., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-05-19
Release date:2017-06-14
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of Glycerophosphoryl Diester Phosphodiesterase Domain of Uncharacterized Protein Rv2277c from Mycobacterium tuberculosis
To Be Published
5VPJ
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THE CRYSTAL STRUCTURE OF A THIOESTERAS FROM ACTINOMADURA VERRUCOSOSPORA.
Descriptor:Thioesterase, CHLORIDE ION, TETRAETHYLENE GLYCOL
Authors:Tan, K., Joachimiak, G., Endres, M., Phillips Jr., G.N., Joachmiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2017-05-05
Release date:2017-07-19
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The crystal structure of a thioesteras from Actinomadura verrucosospora.
To Be Published
5VES
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THE 2.4A CRYSTAL STRUCTURE OF OMPA DOMAIN OF OMPA FROM SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM STR. 14028S
Descriptor:Outer membrane protein A, SULFATE ION
Authors:Tan, K., Wu, R., Jedrzejczak, R., Adkins, J., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP)
Deposit date:2017-04-05
Release date:2017-04-19
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The 2.4A crystal structure of OmpA domain of OmpA from Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S
To Be Published
5VDB
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CRYSTAL STRUCTURE OF A GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794 IN COMPLEX WITH BISUBSTRATE ANALOG 3
Descriptor:acetyltransferase PA4794, SULFATE ION, (3R,5S,9R,26S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,20-trioxo-26-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15,21-triaza-3,5-diphosphaheptacosan-27-oic acid 3,5-dioxide (non-preferred name)
Authors:Majorek, K.A., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-04-01
Release date:2017-07-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
FEBS Lett., 591, 2017
5VD6
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CRYSTAL STRUCTURE OF A GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794 IN COMPLEX WITH BISUBSTRATE ANALOG 6
Descriptor:acetyltransferase PA4794, SULFATE ION, (3R,5S,9R,23S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14-dioxo-23-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatetracosan-24-oic acid 3,5-dioxide (non-preferred name)
Authors:Majorek, K.A., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-04-01
Release date:2017-07-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
FEBS Lett., 591, 2017
5UVE
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CRYSTAL STRUCTURE OF THE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN BAB1_0226 FROM BRUCELLA ABORTUS
Descriptor:Substrate-binding region of ABC-type glycine betaine transport system, CALCIUM ION, GLYCEROL
Authors:Kim, Y., Chhor, G., Endres, M., Hero, J., Babnigg, G., Crosson, S., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-02-20
Release date:2017-03-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Beta-barrel-like Protein of Unknown Function
To Be Published
5UQP
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THE CRYSTAL STRUCTURE OF CUPIN PROTEIN FROM RHODOCOCCUS JOSTII RHA1
Descriptor:Cupin, ZINC ION, CHLORIDE ION, ...
Authors:Tan, K., Li, H., Clancy, S., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2017-02-08
Release date:2017-02-22
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of cupin protein from Rhodococcus jostii RHA1
To Be Published
5UPT
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ACYL-COA SYNTHETASE PTMA2 FROM STREPTOMYCES PLATENSIS IN COMPLEX WITH SBNP468 LIGAND
Descriptor:Acyl-CoA synthetase PtmA2, (7alpha,8alpha,10alpha,13alpha)-7,16-dihydroxykauran-18-oic acid, SULFATE ION, ...
Authors:Osipiuk, J., Hatzos-Skintges, C., Endres, M., Babnigg, G., Rudolf, J.D., Chang, C.Y., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2017-02-03
Release date:2017-02-22
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme.
Nat. Chem. Biol., 14, 2018