Author results

1AV5
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PKCI-SUBSTRATE ANALOG
Descriptor:PROTEIN KINASE C INTERACTING PROTEIN, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER
Authors:Lima, C.D., Klein, M.G., Hendrickson, W.A.
Deposit date:1997-09-25
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Science, 278, 1997
1ECL
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AMINO TERMINAL 67KDA DOMAIN OF ESCHERICHIA COLI DNA TOPOISOMERASE I (RESIDUES 2-590 OF MATURE PROTEIN) CLONING ARTIFACT ADDS TWO RESIDUES TO THE AMINO-TERMINUS WHICH WERE NOT OBSERVED IN THE EXPERIMENTAL ELECTRON DENSITY (GLY-2, SER-1).
Descriptor:ESCHERICHIA COLI TOPOISOMERASE I
Authors:Lima, C.D., Wang, J.C., Mondragon, A.
Deposit date:1995-05-05
Release date:1995-07-31
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I.
Nature, 367, 1994
1KPE
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PKCI-TRANSITION STATE ANALOG
Descriptor:PROTEIN KINASE C INTERACTING PROTEIN, ADENOSINE-5'-DITUNGSTATE
Authors:Lima, C.D., Klein, M.G., Hendrickson, W.A.
Deposit date:1997-09-25
Release date:1998-03-25
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Science, 278, 1997
1KPF
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PKCI-SUBSTRATE ANALOG
Descriptor:PROTEIN KINASE C INTERACTING PROTEIN, ADENOSINE MONOPHOSPHATE
Authors:Lima, C.D., Klein, M.G., Hendrickson, W.A.
Deposit date:1997-09-25
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Science, 278, 1997
4FIT
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FHIT-APO
Descriptor:FRAGILE HISTIDINE TRIAD PROTEIN
Authors:Lima, C.D., Klein, M.G., Hendrickson, W.A.
Deposit date:1997-09-25
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Science, 278, 1997
5FIT
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FHIT-SUBSTRATE ANALOG
Descriptor:FRAGILE HISTIDINE TRIAD PROTEIN, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER
Authors:Lima, C.D., Klein, M.G., Hendrickson, W.A.
Deposit date:1997-09-25
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Science, 278, 1997
6FIT
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FHIT-TRANSITION STATE ANALOG
Descriptor:FRAGILE HISTIDINE TRIAD PROTEIN, ADENOSINE MONOTUNGSTATE
Authors:Lima, C.D., Klein, M.G., Hendrickson, W.A.
Deposit date:1997-09-25
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Science, 278, 1997
1D8H
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X-RAY CRYSTAL STRUCTURE OF YEAST RNA TRIPHOSPHATASE IN COMPLEX WITH SULFATE AND MANGANESE IONS.
Descriptor:mRNA TRIPHOSPHATASE CET1, MANGANESE (II) ION, SULFATE ION
Authors:Lima, C.D., Wang, L.K., Shuman, S.
Deposit date:1999-10-24
Release date:1999-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus.
Cell(Cambridge,Mass.), 99, 1999
1D8I
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X-RAY CRYSTAL STRUCTURE OF YEAST RNA TRIPHOSPHATASE IN COMPLEX WITH A SULFATE ION.
Descriptor:MRNA TRIPHOSPHATASE CET1, SULFATE ION
Authors:Lima, C.D., Wang, L.K., Shuman, S.
Deposit date:1999-10-24
Release date:1999-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus.
Cell(Cambridge,Mass.), 99, 1999
1FIT
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FHIT (FRAGILE HISTIDINE TRIAD PROTEIN)
Descriptor:FRAGILE HISTIDINE PROTEIN, FRUCTOSE, SULFATE ION
Authors:Lima, C.D., D'Amico, K.L., Naday, I., Rosenbaum, G., Westbrook, E.M., Hendrickson, W.A.
Deposit date:1997-05-17
Release date:1997-11-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family.
Structure, 5, 1997
1JF9
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CRYSTAL STRUCTURE OF SELENOCYSTEINE LYASE
Descriptor:SELENOCYSTEINE LYASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Lima, C.D., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-06-20
Release date:2001-07-04
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Analysis of the E. coli NifS CsdB Protein at 2.0A Reveals the Structural Basis for Perselenide and Persulfide Intermediate Formation
J.Mol.Biol., 315, 2002
1KMJ
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E. COLI NIFS/CSDB PROTEIN AT 2.0A WITH THE CYSTEINE PERSULFIDE INTERMEDIATE (RESIDUE CSS).
Descriptor:Selenocysteine lyase, PYRIDOXAL-5'-PHOSPHATE
Authors:Lima, C.D., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-12-16
Release date:2001-12-21
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Analysis of the E. coli NifS CsdB protein at 2.0 A reveals the structural basis for perselenide and persulfide intermediate formation.
J.Mol.Biol., 315, 2002
1KMK
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E. COLI NIFS/CSDB PROTEIN AT 2.20A WITH THE CYSTEINE PERSELENIDE INTERMEDIATE (RESIDUE CSZ).
Descriptor:SELENOCYSTEINE LYASE, SELENOCYSTEINE, PYRIDOXAL-5'-PHOSPHATE
Authors:Lima, C.D., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-12-16
Release date:2001-12-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Analysis of the E. coli NifS CsdB protein at 2.0 A reveals the structural basis for perselenide and persulfide intermediate formation.
J.Mol.Biol., 315, 2002
1KPA
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PKCI-1-ZINC
Descriptor:HUMAN PROTEIN KINASE C INTERACTING PROTEIN 1 (ZINC PROTEIN)
Authors:Lima, C.D., Klein, M.G., Weinstein, I.B., Hendrickson, W.A.
Deposit date:1996-01-06
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins.
Proc.Natl.Acad.Sci.USA, 93, 1996
1KPB
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PKCI-1-APO
Descriptor:HUMAN PROTEIN KINASE C INTERACTING PROTEIN 1 (ZINC PROTEIN)
Authors:Lima, C.D., Klein, M.G., Weinstein, I.B., Hendrickson, W.A.
Deposit date:1996-01-06
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins.
Proc.Natl.Acad.Sci.USA, 93, 1996
1KPC
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PKCI-1-APO+ZINC
Descriptor:HUMAN PROTEIN KINASE C INTERACTING PROTEIN 1 (ZINC PROTEIN)
Authors:Lima, C.D., Klein, M.G., Weinstein, I.B., Hendrickson, W.A.
Deposit date:1996-01-06
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins.
Proc.Natl.Acad.Sci.USA, 93, 1996
1RI6
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STRUCTURE OF A PUTATIVE ISOMERASE FROM E. COLI
Descriptor:putative isomerase ybhE
Authors:Lima, C.D., Kniewel, R., Solorzano, V., Wu, J., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2003-11-16
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a putative 7-bladed propeller isomerase
To be Published
2FIT
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FHIT (FRAGILE HISTIDINE TRIAD PROTEIN)
Descriptor:FRAGILE HISTIDINE PROTEIN, FRUCTOSE, SULFATE ION
Authors:Lima, C.D., D'Amico, K.L., Naday, I., Rosenbaum, G., Westbrook, E.M., Hendrickson, W.A.
Deposit date:1997-05-17
Release date:1997-11-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family.
Structure, 5, 1997
3EAY
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CRYSTAL STRUCTURE OF THE HUMAN SENP7 CATALYTIC DOMAIN
Descriptor:Sentrin-specific protease 7, SULFATE ION
Authors:Lima, C.D., Reverter, D.
Deposit date:2008-08-26
Release date:2008-09-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Human SENP7 Catalytic Domain and Poly-SUMO Deconjugation Activities for SENP6 and SENP7.
J.Biol.Chem., 283, 2008
3FIT
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FHIT (FRAGILE HISTIDINE TRIAD PROTEIN) IN COMPLEX WITH ADENOSINE/SULFATE AMP ANALOG
Descriptor:FRAGILE HISTIDINE PROTEIN, FRUCTOSE, SULFATE ION, ...
Authors:Lima, C.D., D'Amico, K.L., Naday, I., Rosenbaum, G., Westbrook, E.M., Hendrickson, W.A.
Deposit date:1997-05-17
Release date:1997-11-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family.
Structure, 5, 1997
6DG4
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STRUCTURE OF THE CHAETOMIUM THERMOPHILUM ULP1-LIKE SUMO PROTEASE CATALYTIC DOMAIN
Descriptor:Ulp1-like SUMO protease, SULFATE ION, GLYCEROL
Authors:Lima, C.D., Baytshtok, V.
Deposit date:2018-05-16
Release date:2018-07-11
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (1.442 Å)
Cite:Discovery and engineering of enhanced SUMO protease enzymes.
J. Biol. Chem., 293, 2018
3KYD
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HUMAN SUMO E1~SUMO1-AMP TETRAHEDRAL INTERMEDIATE MIMIC
Descriptor:SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, Small ubiquitin-related modifier 1, ...
Authors:Lima, C.D.
Deposit date:2009-12-05
Release date:2010-02-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Active site remodelling accompanies thioester bond formation in the SUMO E1.
Nature, 463, 2010
1JR7
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CRYSTAL STRUCTURE OF GAB REVEALS OXIDOREDUCTASE FOLD
Descriptor:HYPOTHETICAL 37.4 KDA PROTEIN IN ILEY-GABD INTERGENIC REGION, FE (II) ION
Authors:Lima, C.D., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-08-12
Release date:2001-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural genomics: a pipeline for providing structures for the biologist.
Protein Sci., 11, 2002
2HV9
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ENCEPHALITOZOON CUNICULI MRNA CAP (GUANINE-N7) METHYLTRANSFERASE IN COMPLEX WITH SINEFUNGIN
Descriptor:mRNA cap guanine-N7 methyltransferase, SINEFUNGIN
Authors:Lima, C.D.
Deposit date:2006-07-27
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mutational Analysis of Encephalitozoon cuniculi mRNA Cap (Guanine-N7) Methyltransferase, Structure of the Enzyme Bound to Sinefungin, and Evidence That Cap Methyltransferase Is the Target of Sinefungin's Antifungal Activity
J.Biol.Chem., 281, 2006
2NN6
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STRUCTURE OF THE HUMAN RNA EXOSOME COMPOSED OF RRP41, RRP45, RRP46, RRP43, MTR3, RRP42, CSL4, RRP4, AND RRP40
Descriptor:Polymyositis/scleroderma autoantigen 1, Exosome complex exonuclease RRP41, Exosome complex exonuclease RRP43, ...
Authors:Lima, C.D.
Deposit date:2006-10-23
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Reconstitution, activities, and structure of the eukaryotic RNA exosome.
Cell(Cambridge,Mass.), 127, 2006