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1D9W
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BACTERIOPHAGE T4 LYSOZYME MUTANT
Descriptor:PROTEIN (LYSOZYME), BETA-MERCAPTOETHANOL
Authors:Korndoerfer, I.P., Matthews, B.W.
Deposit date:1999-10-30
Release date:1999-11-17
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Helix Capping in Bacteriophage T4 Lysozyme
To be Published
1KXO
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ENGINEERED LIPOCALIN DIGA16 : APO-FORM
Descriptor:DigA16
Authors:Korndoerfer, I.P., Skerra, A.
Deposit date:2002-02-01
Release date:2003-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural mechanism of specific ligand recognition by a lipocalin tailored for the complexation of digoxigenin.
J.Mol.Biol., 330, 2003
1LKE
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ENGINEERED LIPOCALIN DIGA16 IN COMPLEX WITH DIGOXIGENIN
Descriptor:DigA16, DIGOXIGENIN
Authors:Korndoerfer, I.P., Skerra, A.
Deposit date:2002-04-25
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural mechanism of specific ligand recognition by a lipocalin tailored for the complexation of digoxigenin.
J.Mol.Biol., 330, 2003
1LNM
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ANTICALIN DIGA16 IN COMPLEX WITH DIGITOXIGENIN
Descriptor:DigA16, DIGITOXIGENIN
Authors:Korndoerfer, I.P., Skerra, A.
Deposit date:2002-05-03
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural mechanism of specific ligand recognition by a lipocalin tailored for the complexation of digoxigenin.
J.Mol.Biol., 330, 2003
1XK4
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CRYSTAL STRUCTURE OF HUMAN CALPROTECTIN(S100A8/S100A9)
Descriptor:Calgranulin A, Calgranulin B, CALCIUM ION, ...
Authors:Korndoerfer, I.P., Brueckner, F., Skerra, A.
Deposit date:2004-09-26
Release date:2005-10-18
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of the human (S100A8/S100A9)2 heterotetramer, calprotectin, illustrates how conformational changes of interacting alpha-helices can determine specific association of two EF-hand proteins
J.Mol.Biol., 370, 2007
1XOV
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THE CRYSTAL STRUCTURE OF THE LISTERIA MONOCYTOGENES BACTERIOPHAGE PSA ENDOLYSIN PLYPSA
Descriptor:Ply protein, ZINC ION, SULFATE ION, ...
Authors:Korndoerfer, I.P., Skerra, A.
Deposit date:2004-10-07
Release date:2005-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of the bacteriophage PSA endolysin reveals a unique fold responsible for specific recognition of Listeria cell walls
J.Mol.Biol., 364, 2006
1XKI
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CRYSTAL STRUCTURE OF HUMAN TEAR LIPOCALIN/VON EBNERS GLAND PROTEIN
Descriptor:Von Ebner's gland protein, ZINC ION, CHLORIDE ION
Authors:Breustedt, D.A., Korndoerfer, I.P., Redl, B., Skerra, A.
Deposit date:2004-09-29
Release date:2004-10-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands
J.Biol.Chem., 280, 2005
1KFF
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AN ENGINEERED STREPTAVIDIN WITH IMPROVED AFFINITY FOR THE STREP-TAG II PEPTIDE: APO-SAM1
Descriptor:streptavidin
Authors:Korndoerfer, I.P., Skerra, A.
Deposit date:2001-11-20
Release date:2002-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site.
Protein Sci., 11, 2002
1KL3
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AN ENGINEERED STREPTAVIDIN WITH IMPROVED AFFINITY FOR THE STREP-TAG II PEPTIDE : SAM1-STREPII
Descriptor:streptavidin, strep-tag II peptide
Authors:Korndoerfer, I.P., Skerra, A.
Deposit date:2001-12-11
Release date:2002-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site.
Protein Sci., 11, 2002
1KL4
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AN ENGINEERED STREPTAVIDIN WITH IMPROVED AFFINITY FOR THE STREP-TAG II PEPTIDE : APO-SAM2
Descriptor:streptavidin
Authors:Korndoerfer, I.P., Skerra, A.
Deposit date:2001-12-11
Release date:2002-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site.
Protein Sci., 11, 2002
1KL5
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AN ENGINEERED STREPTAVIDIN WITH IMPROVED AFFINITY FOR THE STREP-TAG II PEPTIDE : SAM2-STREPII
Descriptor:streptavidin, strep-tag II
Authors:Korndoerfer, I.P., Skerra, A.
Deposit date:2001-12-11
Release date:2002-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site.
Protein Sci., 11, 2002
1N0S
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ENGINEERED LIPOCALIN FLUA IN COMPLEX WITH FLUORESCEIN
Descriptor:Bilin-binding protein, 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, SULFATE ION
Authors:Korndoerfer, I.P., Skerra, A.
Deposit date:2002-10-15
Release date:2003-08-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic analysis of an "anticalin" with tailored specificity for fluorescein reveals high structural plasticity of the lipocalin loop region.
Proteins, 53, 2003
2VO9
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CRYSTAL STRUCTURE OF THE ENZYMATICALLY ACTIVE DOMAIN OF THE LISTERIA MONOCYTOGENES BACTERIOPHAGE 500 ENDOLYSIN PLY500
Descriptor:L-ALANYL-D-GLUTAMATE PEPTIDASE, ZINC ION, SULFATE ION
Authors:Korndoerfer, I.P., Kanitz, A., Skerra, A.
Deposit date:2008-02-09
Release date:2008-02-19
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Analysis of the L-Alanoyl-D-Glutamate Endopeptidase Domain of Listeria Bacteriophage Endolysin Ply500 Reveals a New Member of the Las Peptidase Family.
Acta Crystallogr.,Sect.D, 64, 2008
3INW
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HSP90 N-TERMINAL DOMAIN WITH POCHOXIME A
Descriptor:Heat shock protein HSP 90-alpha, DIMETHYL SULFOXIDE, (5E,9E,11E)-13-chloro-14,16-dihydroxy-3,4,7,8-tetrahydro-1H-2-benzoxacyclotetradecine-1,11(12H)-dione 11-[O-(2-oxo-2-piperidin-1-ylethyl)oxime]
Authors:Korndoerfer, I.P.
Deposit date:2009-08-13
Release date:2010-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Inhibition of HSP90 with pochoximes: SAR and structure-based insights.
Chembiochem, 10, 2009
3INX
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HSP90 N-TERMINAL DOMAIN WITH POCHOXIME B
Descriptor:Heat shock protein HSP 90-alpha, DIMETHYL SULFOXIDE, (5E,9E,11E)-14,16-dihydroxy-3,4,7,8-tetrahydro-1H-2-benzoxacyclotetradecine-1,11(12H)-dione 11-[O-(2-oxo-2-piperidin-1-ylethyl)oxime]
Authors:Korndoerfer, I.P.
Deposit date:2009-08-13
Release date:2010-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inhibition of HSP90 with pochoximes: SAR and structure-based insights.
Chembiochem, 10, 2009
5LGE
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CRYSTAL STRUCTURE OF HUMAN IDH1 MUTANT (R132H) IN COMPLEX WITH NADP+ AND AN INHIBITOR RELATED TO BAY 1436032
Descriptor:Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1,2-ETHANEDIOL, ...
Authors:Hillig, R.C., Hars, U., Korndoerfer, I.P.
Deposit date:2016-07-07
Release date:2017-02-08
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo.
Acta Neuropathol., 133, 2017
1SG2
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CRYSTAL STRUCTURE OF THE PERIPLASMIC CHAPERONE SKP
Descriptor:Seventeen Kilodalton Protein
Authors:Korndorfer, I.P., Dommel, M.K., Skerra, A.
Deposit date:2004-02-23
Release date:2004-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of the periplasmic chaperone Skp suggests functional similarity with cytosolic chaperones despite differing architecture.
Nat.Struct.Mol.Biol., 11, 2004