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1VBM
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CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI TYROSYL-TRNA SYNTHETASE COMPLEXED WITH TYR-AMS
Descriptor:Tyrosyl-tRNA synthetase, SULFATE ION, 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE
Authors:Kobayashi, T., Sakamoto, K., Takimura, T., Kamata, K., Sekine, R., Nishimura, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-02-27
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural snapshots of the KMSKS loop rearrangement for amino acid activation by bacterial tyrosyl-tRNA synthetase.
J.Mol.Biol., 346, 2005
1VBN
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ESCHERICHIA COLI TYROSYL-TRNA SYNTHETASE MUTANT COMPLEXED WITH TYR-AMS
Descriptor:Tyrosyl-tRNA synthetase, 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE
Authors:Kobayashi, T., Sakamoto, K., Takimura, T., Kamata, K., Sekine, R., Nishimura, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-02-27
Release date:2005-01-25
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion
Proc.Natl.Acad.Sci.USA, 102, 2005
1WQ3
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ESCHERICHIA COLI TYROSYL-TRNA SYNTHETASE MUTANT COMPLEXED WITH 3-IODO-L-TYROSINE
Descriptor:Tyrosyl-tRNA synthetase, 3-IODO-TYROSINE
Authors:Kobayashi, T., Sakamoto, K., Nureki, O., Takimura, T., Kamata, K., Sekine, R., Nishimura, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-09-20
Release date:2005-01-25
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion
Proc.Natl.Acad.Sci.USA, 102, 2005
1WQ4
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ESCHERICHIA COLI TYROSYL-TRNA SYNTHETASE MUTANT COMPLEXED WITH L-TYROSINE
Descriptor:Tyrosyl-tRNA synthetase, TYROSINE
Authors:Kobayashi, T., Sakamoto, K., Nureki, O., Takimura, T., Kamata, K., Sekine, R., Nishimura, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-09-20
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion
Proc.Natl.Acad.Sci.USA, 102, 2005
1X8X
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TYROSYL T-RNA SYNTHETASE FROM E.COLI COMPLEXED WITH TYROSINE
Descriptor:Tyrosyl-tRNA synthetase, SULFATE ION, TYROSINE
Authors:Kobayashi, T., Takimura, T., Sekine, R., Kelly, V.P., Kamata, K., Sakamoto, K., Nishimura, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-08-19
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Snapshots of the KMSKS Loop Rearrangement for Amino Acid Activation by Bacterial Tyrosyl-tRNA Synthetase
J.MOL.BIOL., 346, 2005
1J1U
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CRYSTAL STRUCTURE OF ARCHAEAL TYROSYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(TYR) AND L-TYROSINE
Descriptor:tRNA(Tyr), Tyrosyl-tRNA synthetase, MAGNESIUM ION, ...
Authors:Kobayashi, T., Nureki, O., Ishitani, R., Tukalo, M., Cusack, S., Sakamoto, K., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-12-17
Release date:2003-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion
NAT.STRUCT.BIOL., 10, 2003
3VG9
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CRYSTAL STRUCTURE OF HUMAN ADENOSINE A2A RECEPTOR WITH AN ALLOSTERIC INVERSE-AGONIST ANTIBODY AT 2.7 A RESOLUTION
Descriptor:Adenosine receptor A2a, antibody fab fragment light chain, antibody fab fragment heavy chain, ...
Authors:Hino, T., Arakawa, T., Iwanari, H., Yurugi-Kobayashi, T., Ikeda-Suno, C., Nakada-Nakura, Y., Kusano-Arai, O., Weyand, S., Shimamura, T., Nomura, N., Cameron, A.D., Kobayashi, T., Hamakubo, T., Iwata, S., Murata, T.
Deposit date:2011-08-04
Release date:2012-02-01
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Nature, 482, 2012
3VGA
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CRYSTAL STRUCTURE OF HUMAN ADENOSINE A2A RECEPTOR WITH AN ALLOSTERIC INVERSE-AGONIST ANTIBODY AT 3.1 A RESOLUTION
Descriptor:Adenosine receptor A2a, antibody fab fragment light chain, antibody fab fragment heavy chain, ...
Authors:Hino, T., Arakawa, T., Iwanari, H., Yurugi-Kobayashi, T., Ikeda-Suno, C., Nakada-Nakura, Y., Kusano-Arai, O., Weyand, S., Shimamura, T., Nomura, N., Cameron, A.D., Kobayashi, T., Hamakubo, T., Iwata, S., Murata, T.
Deposit date:2011-08-04
Release date:2012-02-01
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Nature, 482, 2012
5A16
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CRYSTAL STRUCTURE OF FAB4201 RAISED AGAINST HUMAN ERYTHROCYTE ANION EXCHANGER 1
Descriptor:FAB4201 HEAVY CHAIN
Authors:Arakawa, T., Kobayashi-Yugiri, T., Alguel, Y., Weyand, S., Iwanari, H., Hatae, H., Iwata, M., Abe, Y., Hino, T., Ikeda-Suno, C., Kuma, H., Kang, D., Murata, T., Hamakubo, T., Cameron, A., Kobayashi, T., Hamasaki, N., Iwata, S.
Deposit date:2015-04-28
Release date:2015-06-10
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Anion Exchanger Domain of Human Erythrocyte Band 3
Science, 350, 2015
3UON
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STRUCTURE OF THE HUMAN M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND TO AN ANTAGONIST
Descriptor:Human M2 muscarinic acetylcholine, receptor T4 lysozyme fusion protein, (3R)-1-azabicyclo[2.2.2]oct-3-yl hydroxy(diphenyl)acetate, ...
Authors:Haga, K., Kruse, A.C., Asada, H., Yurugi-Kobayashi, T., Shiroishi, M., Zhang, C., Weis, W.I., Okada, T., Kobilka, B.K., Haga, T., Kobayashi, T.
Deposit date:2011-11-16
Release date:2012-02-01
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.
Nature, 482, 2012
5H0Q
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CRYSTAL STRUCTURE OF LIPID BINDING PROTEIN NAKANORI AT 1.5A
Descriptor:Lipid binding protein
Authors:Makino, A., Abe, M., Ishitsuka, R., Murate, M., Kishimoto, T., Sakai, S., Hullin-Matsuda, F., Shimada, Y., Inaba, T., Miyatake, H., Tanaka, H., Kurahashi, A., Pack, C.G., Kasai, R.S., Kubo, S., Schieber, N.L., Dohmae, N., Tochio, N., Hagiwara, K., Sasaki, Y., Aida, Y., Fujimori, F., Kigawa, T., Nishikori, K., Parton, R.G., Kusumi, A., Sako, Y., Anderluh, G., Yamashita, M., Kobayashi, T., Greimel, P., Kobayashi, T.
Deposit date:2016-10-06
Release date:2016-10-19
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:A novel sphingomyelin/cholesterol domain-specific probe reveals the dynamics of the membrane domains during virus release and in Niemann-Pick type C
FASEB J., 31, 2017
4YZF
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CRYSTAL STRUCTURE OF THE ANION EXCHANGER DOMAIN OF HUMAN ERYTHROCYTE BAND 3
Descriptor:Band 3 anion transport protein, FAB fragment of Immunoglobulin (IgG) molecule, 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid}
Authors:Alguel, Y., Arakawa, T., Yugiri, T.K., Iwanari, H., Hatae, H., Iwata, M., Abe, Y., Hino, T., Suno, C.I., Kuma, H., Kang, D., Murata, T., Hamakubo, T., Cameron, A.D., Kobayashi, T., Hamasaki, N., Iwata, S.
Deposit date:2015-03-25
Release date:2015-11-04
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the anion exchanger domain of human erythrocyte band 3.
Science, 350, 2015
4X8Y
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CRYSTAL STRUCTURE OF HUMAN PGRMC1 CYTOCHROME B5-LIKE DOMAIN
Descriptor:Membrane-associated progesterone receptor component 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Nakane, T., Yamamoto, T., Shimamura, T., Kobayashi, T., Kabe, Y., Suematsu, M.
Deposit date:2014-12-11
Release date:2016-03-23
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
Nat Commun, 7, 2016
5WQC
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CRYSTAL STRUCTURE OF HUMAN OREXIN 2 RECEPTOR BOUND TO THE SELECTIVE ANTAGONIST EMPA DETERMINED BY THE SYNCHROTRON LIGHT SOURCE AT SPRING-8.
Descriptor:Orexin receptor type 2,GlgA glycogen synthase,Orexin receptor type 2, N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide, OLEIC ACID, ...
Authors:Suno, R., Hirata, K., Yamashita, K., Tsujimoto, H., Sasanuma, M., Horita, S., Yamamoto, M., Rosenbaum, D.M., Iwata, S., Shimamura, T., Kobayashi, T.
Deposit date:2016-11-25
Release date:2017-11-29
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA
Structure, 26, 2018
5WS3
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CRYSTAL STRUCTURES OF HUMAN OREXIN 2 RECEPTOR BOUND TO THE SELECTIVE ANTAGONIST EMPA DETERMINED BY SERIAL FEMTOSECOND CRYSTALLOGRAPHY AT SACLA
Descriptor:Orexin receptor type 2,GlgA glycogen synthase,Orexin receptor type 2, N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide, OLEIC ACID, ...
Authors:Suno, R., Kimura, K., Nakane, T., Yamashita, K., Wang, J., Fujiwara, T., Yamanaka, Y., Im, D., Tsujimoto, H., Sasanuma, M., Horita, S., Hirokawa, T., Nango, E., Tono, K., Kameshima, T., Hatsui, T., Joti, Y., Yabashi, M., Shimamoto, K., Yamamoto, M., Rosenbaum, D.M., Iwata, S., Shimamura, T., Kobayashi, T.
Deposit date:2016-12-05
Release date:2017-12-13
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA.
Structure, 26, 2018
5YFI
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CRYSTAL STRUCTURE OF THE ANTI-HUMAN PROSTAGLANDIN E RECEPTOR EP4 ANTIBODY FAB FRAGMENT
Descriptor:Light chain of Fab fragment, Heavy chain of Fab fragment, ZINC ION
Authors:Toyoda, Y., Morimoto, K., Suno, R., Horita, S., Iwata, S., Kobayashi, T.
Deposit date:2017-09-21
Release date:2018-12-05
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.848 Å)
Cite:Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
5YHL
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CRYSTAL STRUCTURE OF THE HUMAN PROSTAGLANDIN E RECEPTOR EP4 IN COMPLEX WITH FAB AND AN ANTAGONIST BR-DERIVATIVE
Descriptor:Prostaglandin E2 receptor EP4 subtype, Heavy chain of Fab fragment, Light chain of Fab fragment, ...
Authors:Toyoda, Y., Morimoto, K., Suno, R., Horita, S., Iwata, S., Kobayashi, T.
Deposit date:2017-09-28
Release date:2018-12-05
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
5YWY
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CRYSTAL STRUCTURE OF THE HUMAN PROSTAGLANDIN E RECEPTOR EP4 IN COMPLEX WITH FAB AND ONO-AE3-208
Descriptor:Prostaglandin E2 receptor EP4 subtype,Prostaglandin E2 receptor EP4 subtype, Heavy chain of Fab fragment, Light chain of Fab fragment, ...
Authors:Toyoda, Y., Morimoto, K., Suno, R., Horita, S., Iwata, S., Kobayashi, T.
Deposit date:2017-11-30
Release date:2018-12-05
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
1WSD
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ALKALINE M-PROTEASE FORM I CRYSTAL STRCUTURE
Descriptor:M-protease, CALCIUM ION, SULFATE ION
Authors:Shirai, T., Suzuki, A., Yamane, T., Ashida, T., Kobayashi, T., Hitomi, J., Ito, S.
Deposit date:2004-11-05
Release date:2004-11-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution crystal structure of M-protease: phylogeny aided analysis of the high-alkaline adaptation mechanism
Protein Eng., 10, 1997
2CYA
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CRYSTAL STRUCTURE OF TYROSYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX
Descriptor:Tyrosyl-tRNA synthetase, SULFATE ION
Authors:Kuratani, M., Sakai, H., Takahashi, M., Yanagisawa, T., Kobayashi, T., Murayama, K., Chen, L., Liu, Z.J., Wang, B.C., Kuroishi, C., Kuramitsu, S., Terada, T., Bessho, Y., Shirouzu, M., Sekine, S.I., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-06
Release date:2005-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of Tyrosyl-tRNA Synthetases from Archaea
J.Mol.Biol., 355, 2005
2CYB
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CRYSTAL STRUCTURE OF TYROSYL-TRNA SYNTHETASE COMPLEXED WITH L-TYROSINE FROM ARCHAEOGLOBUS FULGIDUS
Descriptor:Tyrosyl-tRNA synthetase, TYROSINE
Authors:Kuratani, M., Sakai, H., Takahashi, M., Yanagisawa, T., Kobayashi, T., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-06
Release date:2005-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Tyrosyl-tRNA Synthetases from Archaea
J.Mol.Biol., 355, 2006
2CYC
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CRYSTAL STRUCTURE OF TYROSYL-TRNA SYNTHETASE COMPLEXED WITH L-TYROSINE FROM PYROCOCCUS HORIKOSHII
Descriptor:tyrosyl-tRNA synthetase, TYROSINE
Authors:Kuratani, M., Sakai, H., Takahashi, M., Yanagisawa, T., Kobayashi, T., Sakamoto, K., Terada, T., Shirouzu, M., Sekine, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-06
Release date:2005-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of Tyrosyl-tRNA Synthetases from Archaea
J.Mol.Biol., 355, 2006
2DIE
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ALKALINE ALPHA-AMYLASE AMYK FROM BACILLUS SP. KSM-1378
Descriptor:amylase, CALCIUM ION, SODIUM ION
Authors:Shirai, T., Igarashi, K., Ozawa, T., Hagihara, H., Kobayashi, T., Ozaki, K., Ito, S.
Deposit date:2006-03-29
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ancestral sequence evolutionary trace and crystal structure analyses of alkaline alpha-amylase from Bacillus sp. KSM-1378 to clarify the alkaline adaptation process of proteins
Proteins, 66, 2007
1EE6
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CRYSTAL STRUCTURE OF PECTATE LYASE FROM BACILLUS SP. STRAIN KSM-P15.
Descriptor:PECTATE LYASE, CALCIUM ION
Authors:Akita, M., Suzuki, A., Kobayashi, T., Ito, S., Yamane, T.
Deposit date:2000-01-31
Release date:2001-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The first structure of pectate lyase belonging to polysaccharide lyase family 3.
Acta Crystallogr.,Sect.D, 57, 2001
2ZE0
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ALPHA-GLUCOSIDASE GSJ
Descriptor:Alpha-glucosidase, CALCIUM ION
Authors:Shirai, T., Hung, V.S., Morinaka, K., Kobayashi, T., Ito, S.
Deposit date:2007-12-04
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of GH13 alpha-glucosidase GSJ from one of the deepest sea bacteria
Proteins, 73, 2008