4DKP
Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with AWS-I-50
Summary for 4DKP
Entry DOI | 10.2210/pdb4dkp/pdb |
Related | 4DKO 4DKQ 4DKR |
Descriptor | clade A/E 93TH057 HIV-1 gp120 core, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total) |
Functional Keywords | hiv-1 gp120, clade a/e, cd4 mimic, aws-i-50, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) |
Total number of polymer chains | 2 |
Total formula weight | 84359.46 |
Authors | Kwon, Y.D.,LaLonde, J.M.,Jones, D.M.,Sun, A.W.,Courter, J.R.,Soeta, T.,Kobayashi, T.,Princiotto, A.M.,Wu, X.,Mascola, J.,Schon, A.,Freire, E.,Sodroski, J.,Madani, N.,Smith III, A.B.,Kwong, P.D. (deposition date: 2012-02-03, release date: 2012-05-02, Last modification date: 2023-09-13) |
Primary citation | Lalonde, J.M.,Kwon, Y.D.,Jones, D.M.,Sun, A.W.,Courter, J.R.,Soeta, T.,Kobayashi, T.,Princiotto, A.M.,Wu, X.,Schon, A.,Freire, E.,Kwong, P.D.,Mascola, J.R.,Sodroski, J.,Madani, N.,Smith, A.B. Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors. J.Med.Chem., 55:4382-4396, 2012 Cited by PubMed: 22497421DOI: 10.1021/jm300265j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7978 Å) |
Structure validation
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