Author results

4XHS
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CRYSTAL STRUCTURE OF HUMAN NLRP12 PYD DOMAIN AND IMPLICATION IN HOMOTYPIC INTERACTION
Descriptor:Maltose-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 12, MALTOSE, ...
Authors:Jin, T., Huang, M., Jiang, J., Xiao, T.
Deposit date:2015-01-06
Release date:2016-01-27
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human NLRP12 PYD domain and implication in homotypic interaction
To Be Published
4IFP
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X-RAY CRYSTAL STRUCTURE OF HUMAN NLRP1 CARD DOMAIN
Descriptor:Maltose-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 1, MALTOSE, ...
Authors:Jin, T., Curry, J., Smith, P., Jiang, J., Xiao, T.
Deposit date:2012-12-14
Release date:2013-04-03
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9948 Å)
Cite:Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1.
Proteins, 81, 2013
4IKM
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X-RAY STRUCTURE OF CARD8 CARD DOMAIN
Descriptor:Maltose-binding periplasmic protein, Caspase recruitment domain-containing protein 8, MALTOSE, ...
Authors:Jin, T., Huang, M., Smith, P., Jiang, J., Xiao, T.
Deposit date:2012-12-26
Release date:2013-05-08
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.4606 Å)
Cite:The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces.
Acta Crystallogr.,Sect.F, 69, 2013
4IRL
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X-RAY STRUCTURE OF THE CARD DOMAIN OF ZEBRAFISH GBP-NLRP1 LIKE PROTEIN
Descriptor:Maltose-binding periplasmic protein, Novel protein similar to vertebrate guanylate binding protein family, MALTOTETRAOSE, ...
Authors:Jin, T., Huang, M., Smith, P., Xiao, T.
Deposit date:2013-01-15
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein.
Acta Crystallogr.,Sect.F, 69, 2013
3C3V
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CRYSTAL STRUCTURE OF PEANUT MAJOR ALLERGEN ARA H 3
Descriptor:Arachin Arah3 isoform, SODIUM ION
Authors:Jin, T., Zhang, Y.
Deposit date:2008-01-28
Release date:2009-02-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal structure of Ara h 3, a major allergen in peanut.
Mol.Immunol., 46, 2009
5WPW
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CRYSTAL STRUCTURE OF COCONUT ALLERGEN COCOSIN
Descriptor:11S globulin isoform 1
Authors:Jin, T., Zhang, Y.
Deposit date:2016-11-21
Release date:2017-10-25
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Crystal Structure of Cocosin, A Potential Food Allergen from Coconut (Cocos nucifera)
J. Agric. Food Chem., 65, 2017
5Y3S
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CRYSTAL STRUCTURE OF HUMAN NLRP1 LEUCINE RICH REPEAT DOMAIN
Descriptor:NACHT, LRR and PYD domains-containing protein 1, PHOSPHATE ION, ...
Authors:Jin, T., Xiao, T.S.
Deposit date:2017-07-30
Release date:2018-08-01
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (2.451 Å)
Cite:Crystal structure of human NLRP1 LRR domain
To Be Published
5YZP
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CRYSTAL STRUCTURE OF P204 HINA DOMAIN
Descriptor:Ifi204, 1,2-ETHANEDIOL, ACETATE ION
Authors:Jin, T.
Deposit date:2017-12-15
Release date:2018-12-19
Method:X-RAY DIFFRACTION (1.581 Å)
Cite:Crystal structure of p204 HINa domain
To Be Published
5YZW
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CRYSTAL STRUCTURE OF P204 HINB DOMAIN
Descriptor:Ifi204
Authors:Jin, T.
Deposit date:2017-12-15
Release date:2018-12-19
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Crystal structure of p204 HINb domain at 2.00 Angstroms resolution
To Be Published
5Z7D
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P204HINAB-DSDNA COMPLEX STRUCTURE
Descriptor:Interferon-activable protein 204, DNA (5'-D(P*CP*CP*AP*TP*CP*AP*GP*AP*AP*AP*GP*AP*GP*AP*GP*C)-3')
Authors:Jin, T., Jiang, J., Xiao, T.S.
Deposit date:2018-01-28
Release date:2019-01-30
Method:X-RAY DIFFRACTION (4.504 Å)
Cite:p204-HINab:dsDNA complex structure
To Be Published
5GPP
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CRYSTAL STRUCTURE OF ZEBRAFISH ASC PYD DOMAIN
Descriptor:Maltose-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, MALTOSE, SULFATE ION, ...
Authors:Jin, T., Li, Y.
Deposit date:2016-08-04
Release date:2017-08-09
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Functional and structural characterization of zebrafish ASC.
FEBS J., 285, 2018
5GPQ
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CRYSTAL STRUCTURE OF ZEBRAFISH ASC CARD DOMAIN
Descriptor:Maltose-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, MALTOSE, CITRIC ACID
Authors:Jin, T., Li, Y.
Deposit date:2016-08-04
Release date:2017-08-09
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functional and structural characterization of zebrafish ASC.
FEBS J., 285, 2018
4OI7
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RAGE RECOGNIZES NUCLEIC ACIDS AND PROMOTES INFLAMMATORY RESPONSES TO DNA
Descriptor:Advanced glycosylation end product-specific receptor, 5'-D(*CP*TP*GP*CP*AP*AP*CP*GP*AP*TP*GP*CP*TP*AP*CP*GP*AP*AP*CP*GP*TP*G)-3', 5'-D(*CP*AP*CP*GP*TP*TP*CP*GP*TP*AP*GP*CP*AP*TP*CP*GP*TP*TP*GP*CP*AP*G)-3', ...
Authors:Jin, T., Jiang, J., Xiao, T.
Deposit date:2014-01-19
Release date:2014-04-30
Method:X-RAY DIFFRACTION (3.104 Å)
Cite:RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
J.Exp.Med., 210, 2013
4OI8
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RAGE IS A NUCLEIC ACID RECEPTOR THAT PROMOTES INFLAMMATORY RESPONSES TO DNA.
Descriptor:Advanced glycosylation end product-specific receptor, 5'-D(*CP*CP*AP*TP*GP*AP*CP*TP*GP*TP*AP*GP*GP*AP*AP*AP*CP*TP*CP*TP*AP*GP*A)-3', 5'-D(*CP*TP*CP*TP*AP*GP*AP*GP*TP*TP*TP*CP*CP*TP*AP*CP*AP*GP*TP*CP*AP*TP*G)-3'
Authors:Jin, T., Jiang, J., Xiao, T.
Deposit date:2014-01-19
Release date:2014-04-30
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
J.Exp.Med., 210, 2013
5Y2G
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STRUCTURE OF MBP TAGGED GBS CAMP
Descriptor:Maltose-binding periplasmic protein,Protein B, MALTOSE, SULFATE ION
Authors:Jin, T., Li, Y.
Deposit date:2017-07-25
Release date:2019-02-27
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure determination of the CAMP factor of Streptococcus agalactiae with the aid of an MBP tag and insights into membrane-surface attachment.
Acta Crystallogr D Struct Biol, 75, 2019
5Y37
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CRYSTAL STRUCTURE OF GBS GAPDH
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
Authors:Jin, T., Zhou, K.
Deposit date:2017-07-28
Release date:2018-04-18
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:High-resolution crystal structure of Streptococcus agalactiae glyceraldehyde-3-phosphate de­hydrogenase
Acta Crystallogr.,Sect.F, 74, 2018
5ZNZ
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STRUCTURE OF MDR3 DD WITH MBP TAG MUTANT-I387V
Descriptor:Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25, SULFATE ION
Authors:Jin, T., Yin, X.
Deposit date:2018-04-12
Release date:2019-04-17
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure and activation mechanism of DR3 death domain.
Febs J., 286, 2019
5GOZ
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CRYSTAL STRUCTURE OF ZIKV NS5 METHYLTRANSFERASE IN COMPLEX WITH GTP AND SAH
Descriptor:RNA-directed RNA polymerase NS5, GUANOSINE-5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Zhang, C., Jin, T.
Deposit date:2016-07-30
Release date:2016-12-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design
Biochem. Biophys. Res. Commun., 492, 2017
5GP1
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CRYSTAL STRUCTURE OF ZIKV NS5 METHYLTRANSFERASE IN COMPLEX WITH GTP AND SAH
Descriptor:RNA-directed RNA polymerase NS5, SULFATE ION, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ...
Authors:Zhang, C., Jin, T.
Deposit date:2016-07-30
Release date:2016-12-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.444 Å)
Cite:Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design
Biochem. Biophys. Res. Commun., 492, 2017
5JWH
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APO STRUCTURE
Descriptor:NS3 helicase, 1,2-ETHANEDIOL
Authors:Cao, X., Li, Y., Jin, T.
Deposit date:2016-05-12
Release date:2016-11-09
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular mechanism of divalent-metal-induced activation of NS3 helicase and insights into Zika virus inhibitor design.
Nucleic Acids Res., 44, 2016
5K8I
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APO STRUCTURE
Descriptor:ZIKV NS3 helicase, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
Authors:Cao, X., Li, Y., Jin, T.
Deposit date:2016-05-30
Release date:2016-11-09
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.694 Å)
Cite:Molecular mechanism of divalent-metal-induced activation of NS3 helicase and insights into Zika virus inhibitor design.
Nucleic Acids Res., 44, 2016
5K8L
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APO STRUCTURE
Descriptor:ZIKV NS3 helicase, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Cao, X., Li, Y., Jin, T.
Deposit date:2016-05-30
Release date:2016-11-09
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Molecular mechanism of divalent-metal-induced activation of NS3 helicase and insights into Zika virus inhibitor design.
Nucleic Acids Res., 44, 2016
5K8T
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CRYSTAL STRUCTURE OF ZIKV NS3 HELICASE IN COMPLEX WITH GTP-GAMMAR S AND AN MAGNESIUM ION
Descriptor:ZIKV NS3 helicase, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CHLORIDE ION, ...
Authors:Cao, X., Li, Y., Jin, T.
Deposit date:2016-05-31
Release date:2016-11-09
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.848 Å)
Cite:Molecular mechanism of divalent-metal-induced activation of NS3 helicase and insights into Zika virus inhibitor design.
Nucleic Acids Res., 44, 2016
5K8U
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APO STRUCTURE
Descriptor:zika virus NS3 helicase, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Cao, X., Li, Y., Jin, T.
Deposit date:2016-05-31
Release date:2016-11-09
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Molecular mechanism of divalent-metal-induced activation of NS3 helicase and insights into Zika virus inhibitor design.
Nucleic Acids Res., 44, 2016
5VR3
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CRYSTAL STRUCTURE OF THE BRS DOMAIN OF BRAF
Descriptor:BRAF, SULFATE ION
Authors:Thevakumaran, N., Maisonneuve, P., Kurinov, I., Lavoie, H., Marullo, S.A., Sahmi, M., Jin, T., Therrien, M., Sicheri, F.
Deposit date:2017-05-10
Release date:2018-02-14
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:MEK drives BRAF activation through allosteric control of KSR proteins.
Nature, 554, 2018
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