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1D99
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STRUCTURAL FEATURES AND HYDRATION OF A DODECAMER DUPLEX CONTAINING TWO C.A MISPAIRS
分子名称:DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*CP*GP*CP*G)-3')
著者Hunter, W.N., Brown, T., Kennard, O.
登録日1992-10-17
公開日1993-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural features and hydration of a dodecamer duplex containing two C.A mispairs.
Nucleic Acids Res., 15, 1987
113D
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THE STRUCTURE OF GUANOSINE-THYMIDINE MISMATCHES IN B-DNA AT 2.5 ANGSTROMS RESOLUTION
分子名称:DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*TP*GP*CP*G)-3')
著者Hunter, W.N., Brown, T., Kneale, G., Anand, N.N., Rabinovich, D., Kennard, O.
登録日1993-01-04
公開日1993-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of guanosine-thymidine mismatches in B-DNA at 2.5-A resolution.
J.Biol.Chem., 262, 1987
1D92
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REFINED CRYSTAL STRUCTURE OF AN OCTANUCLEOTIDE DUPLEX WITH G.T MISMATCHED BASE-PAIRS
分子名称:DNA (5'-D(*GP*GP*GP*GP*CP*TP*CP*C)-3')
著者Hunter, W.N., Kneale, G., Brown, T., Rabinovich, D., Kennard, O.
登録日1992-10-17
公開日1993-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Refined crystal structure of an octanucleotide duplex with G . T mismatched base-pairs.
J.Mol.Biol., 190, 1986
1D93
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STRUCTURAL VARIATION IN D(CTCTAGAG). IMPLICATIONS FOR PROTEIN-DNA INTERACTIONS
分子名称:DNA (5'-D(*CP*TP*CP*TP*AP*GP*AP*G)-3')
著者Hunter, W.N., Langlois D'Estaintot, B., Kennard, O.
登録日1992-10-17
公開日1993-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural variation in d(CTCTAGAG). Implications for protein-DNA interactions.
Biochemistry, 28, 1989
3ELC
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CLYCODIPHOSPHATE SYNTHASE COMPLEXED WITH LIGAND
分子名称:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-pyrimidin-2-one, ...
著者Hunter, W.N., Ramsden, N.L., Ulaganathan, V.
登録日2008-09-22
公開日2009-08-25
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem., 52, 2009
3EOR
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CLYCODIPHOSPHATE SYNTHASE COMPLEXED WITH LIGAND
分子名称:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, SODIUM ION, ...
著者Hunter, W.N., Ramsden, N.L., Dawson, A.
登録日2008-09-29
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem., 52, 2009
3ERN
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CLYCODIPHOSPHATE SYNTHASE COMPLEXED WITH ARACMP
分子名称:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, CYTOSINE ARABINOSE-5'-PHOSPHATE, ...
著者Hunter, W.N., Ramsden, N.L., Kemp, L.A.
登録日2008-10-02
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem., 52, 2009
3ESJ
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CLYCODIPHOSPHATE SYNTHASE COMPLEXED WITH LIGAND
分子名称:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 4-amino-1-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]pyrimidin-2(1H)-one, ...
著者Hunter, W.N., Ramsden, N.L.
登録日2008-10-06
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem., 52, 2009
3FBA
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CLYCODIPHOSPHATE SYNTHASE COMPLEXED WITH LIGAND
分子名称:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, [(2S,3S,4R,5S)-5-(4-amino-2-oxo-pyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate, ...
著者Hunter, W.N., Ramsden, N.L.
登録日2008-11-19
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem., 52, 2009
1TYT
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CRYSTAL AND MOLECULAR STRUCTURE OF CRITHIDIA FASCICULATA TRYPANOTHIONE REDUCTASE AT 2.6 ANGSTROMS RESOLUTION
分子名称:TRYPANOTHIONE REDUCTASE, OXIDIZED FORM, FLAVIN-ADENINE DINUCLEOTIDE
著者Bailey, S., Hunter, W.N.
登録日1993-06-10
公開日1994-07-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of trypanothione reductase from Crithidia fasciculata at 2.6 A resolution; enzyme-NADP interactions at 2.8 A resolution.
Acta Crystallogr.,Sect.D, 50, 1994
1TYP
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SUBSTRATE INTERACTIONS BETWEEN TRYPANOTHIONE REDUCTASE AND N1-GLUTATHIONYLSPERMIDINE DISULPHIDE AT 0.28-NM RESOLUTION
分子名称:TRYPANOTHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Bailey, S., Hunter, W.N.
登録日1992-06-29
公開日1994-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Substrate interactions between trypanothione reductase and N1-glutathionylspermidine disulphide at 0.28-nm resolution.
Eur.J.Biochem., 213, 1993
1AOG
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TRYPANOSOMA CRUZI TRYPANOTHIONE REDUCTASE (OXIDIZED FORM)
分子名称:TRYPANOTHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, MALEIC ACID
著者Bond, C.S., Zhang, Y., Hunter, W.N.
登録日1997-07-03
公開日1997-09-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of trypanothione reductase from the human pathogen Trypanosoma cruzi at 2.3 A resolution.
Protein Sci., 5, 1996
1B57
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CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE IN COMPLEX WITH PHOSPHOGLYCOLOHYDROXAMATE
分子名称:PROTEIN (FRUCTOSE-BISPHOSPHATE ALDOLASE II), ZINC ION, SODIUM ION, ...
著者Hall, D.R., Hunter, W.N.
登録日1999-01-12
公開日2000-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of Escherichia coli class II fructose-1, 6-bisphosphate aldolase in complex with phosphoglycolohydroxamate reveals details of mechanism and specificity.
J.Mol.Biol., 287, 1999
1B9M
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REGULATOR FROM ESCHERICHIA COLI
分子名称:PROTEIN (MODE), NICKEL (II) ION
著者Hall, D.R., Gourley, D.G., Hunter, W.N.
登録日1999-02-12
公開日2000-03-15
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The high-resolution crystal structure of the molybdate-dependent transcriptional regulator (ModE) from Escherichia coli: a novel combination of domain folds.
EMBO J., 18, 1999
1B9N
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REGULATOR FROM ESCHERICHIA COLI
分子名称:PROTEIN (MODE), NICKEL (II) ION
著者Hall, D.R., Gourley, D.G., Hunter, W.N.
登録日1999-02-12
公開日2000-03-15
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The high-resolution crystal structure of the molybdate-dependent transcriptional regulator (ModE) from Escherichia coli: a novel combination of domain folds.
EMBO J., 18, 1999
1H47
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STRUCTURES OF MECP SYNTHASE IN COMPLEX WITH (I) CMP AND (II) CMP AND PRODUCT
分子名称:2C-METHYL-D-ERYTHRITOL-2,4-CYCLODIPHOSPHATE SYNTHASE, GERANYL DIPHOSPHATE, ZINC ION, ...
著者Kemp, L.E., Alphey, M.S., Bond, C.S., Hunter, W.N.
登録日2003-02-24
公開日2004-10-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The Identification of Isoprenoids that Bind in the Intersubunit Cavity of Escherichia Coli 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase by Complementary Biophysical Methods
Acta Crystallogr.,Sect.D, 61, 2005
1O7U
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RADIATION INDUCED TRYPAREDOXIN-I
分子名称:TRYPAREDOXIN
著者Alphey, M.S., Bond, C.S., McSweeney, S.M., Hunter, W.N.
登録日2002-11-14
公開日2003-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
1O85
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RADIATION-REDUCED TRYPAREDOXIN-I
分子名称:TRYPAREDOXIN
著者Alphey, M.S., Bond, C.S., Hunter, W.N.
登録日2002-11-25
公開日2003-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
1O8W
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RADIATION-REDUCED TRYPAREDOXIN-I
分子名称:TRYPAREDOXIN
著者Alphey, M.S., Bond, C.S., Hunter, W.N.
登録日2002-12-09
公開日2003-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
1O8X
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MUTANT TRYPAREDOXIN-I CYS43ALA
分子名称:TRYPAREDOXIN
著者Alphey, M.S., Bond, C.S., Hunter, W.N.
登録日2002-12-09
公開日2003-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
1ZEN
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CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE
分子名称:CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE, ZINC ION
著者Cooper, S.J., Leonard, G.A., Hunter, W.N.
登録日1996-07-08
公開日1997-07-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of a class II fructose-1,6-bisphosphate aldolase shows a novel binuclear metal-binding active site embedded in a familiar fold.
Structure, 4, 1996
2BNM
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THE STRUCTURE OF HYDROXYPROPYLPHOSPHONIC ACID EPOXIDASE FROM S. WEDMORENIS.
分子名称:EPOXIDASE, ZINC ION, SULFATE ION
著者McLuskey, K., Cameron, S., Hunter, W.N.
登録日2005-03-29
公開日2005-10-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and Reactivity of Hydroxypropylphosphonic Acid Epoxidase in Fosfomycin Biosynthesis by a Cation- and Flavin-Dependent Mechanism.
Proc.Natl.Acad.Sci.USA, 102, 2005
2BNN
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THE STRUCTURE OF HYDROXYPROPYLPHOSPHONIC ACID EPOXIDASE FROM S. WEDMORENIS IN COMPLEX WITH FOSFOMYCIN
分子名称:EPOXIDASE, FOSFOMYCIN, ZINC ION
著者McLuskey, K., Cameron, S., Hunter, W.N.
登録日2005-03-29
公開日2005-10-05
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Reactivity of Hydroxypropylphosphonic Acid Epoxidase in Fosfomycin Biosynthesis by a Cation- and Flavin-Dependent Mechanism.
Proc.Natl.Acad.Sci.USA, 102, 2005
2BNO
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THE STRUCTURE OF HYDROXYPROPYLPHOSPHONIC ACID EPOXIDASE FROM S. WEDMORENIS.
分子名称:EPOXIDASE, MERCURY (II) ION, ZINC ION, ...
著者McLuskey, K., Cameron, S., Hunter, W.N.
登録日2005-03-29
公開日2005-10-05
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and Reactivity of Hydroxypropylphosphonic Acid Epoxidase in Fosfomycin Biosynthesis by a Cation- and Flavin-Dependent Mechanism.
Proc.Natl.Acad.Sci.USA, 102, 2005
2HKE
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MEVALONATE DIPHOSPHATE DECARBOXYLASE FROM TRYPANOSOMA BRUCEI
分子名称:Diphosphomevalonate decarboxylase, putative, SULFATE ION
著者Byres, E., Alphey, M.S., Hunter, W.N.
登録日2006-07-04
公開日2007-06-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of Trypanosoma brucei and Staphylococcus aureus Mevalonate Diphosphate Decarboxylase Inform on the Determinants of Specificity and Reactivity
J.Mol.Biol., 371, 2007