1D99 | |
113D | | THE STRUCTURE OF GUANOSINE-THYMIDINE MISMATCHES IN B-DNA AT 2.5 ANGSTROMS RESOLUTION | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*TP*GP*CP*G)-3') | | Authors: | Hunter, W.N., Brown, T., Kneale, G., Anand, N.N., Rabinovich, D., Kennard, O. | | Deposit date: | 1993-01-04 | | Release date: | 1993-07-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The structure of guanosine-thymidine mismatches in B-DNA at 2.5-A resolution.
J.Biol.Chem., 262, 1987
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1D92 | | REFINED CRYSTAL STRUCTURE OF AN OCTANUCLEOTIDE DUPLEX WITH G.T MISMATCHED BASE-PAIRS | | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*CP*TP*CP*C)-3') | | Authors: | Hunter, W.N., Kneale, G., Brown, T., Rabinovich, D., Kennard, O. | | Deposit date: | 1992-10-17 | | Release date: | 1993-07-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Refined crystal structure of an octanucleotide duplex with G . T mismatched base-pairs.
J.Mol.Biol., 190, 1986
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1D93 | |
3ELC | | CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CLYCODIPHOSPHATE SYNTHASE COMPLEXED WITH LIGAND | | Descriptor: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-pyrimidin-2-one, ... | | Authors: | Hunter, W.N., Ramsden, N.L., Ulaganathan, V. | | Deposit date: | 2008-09-22 | | Release date: | 2009-08-25 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem., 52, 2009
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3EOR | | CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CLYCODIPHOSPHATE SYNTHASE COMPLEXED WITH LIGAND | | Descriptor: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, SODIUM ION, ... | | Authors: | Hunter, W.N., Ramsden, N.L., Dawson, A. | | Deposit date: | 2008-09-29 | | Release date: | 2009-08-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem., 52, 2009
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3ERN | | CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CLYCODIPHOSPHATE SYNTHASE COMPLEXED WITH ARACMP | | Descriptor: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, CYTOSINE ARABINOSE-5'-PHOSPHATE, ... | | Authors: | Hunter, W.N., Ramsden, N.L., Kemp, L.A. | | Deposit date: | 2008-10-02 | | Release date: | 2009-08-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem., 52, 2009
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3ESJ | | CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CLYCODIPHOSPHATE SYNTHASE COMPLEXED WITH LIGAND | | Descriptor: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 4-amino-1-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]pyrimidin-2(1H)-one, ... | | Authors: | Hunter, W.N., Ramsden, N.L. | | Deposit date: | 2008-10-06 | | Release date: | 2009-08-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem., 52, 2009
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3FBA | | CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CLYCODIPHOSPHATE SYNTHASE COMPLEXED WITH LIGAND | | Descriptor: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, [(2S,3S,4R,5S)-5-(4-amino-2-oxo-pyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate, ... | | Authors: | Hunter, W.N., Ramsden, N.L. | | Deposit date: | 2008-11-19 | | Release date: | 2009-08-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem., 52, 2009
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1TYT | |
1TYP | |
1AOG | |
1B57 | | CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE IN COMPLEX WITH PHOSPHOGLYCOLOHYDROXAMATE | | Descriptor: | PROTEIN (FRUCTOSE-BISPHOSPHATE ALDOLASE II), ZINC ION, SODIUM ION, ... | | Authors: | Hall, D.R., Hunter, W.N. | | Deposit date: | 1999-01-12 | | Release date: | 2000-01-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure of Escherichia coli class II fructose-1, 6-bisphosphate aldolase in complex with phosphoglycolohydroxamate reveals details of mechanism and specificity.
J.Mol.Biol., 287, 1999
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1B9M | | REGULATOR FROM ESCHERICHIA COLI | | Descriptor: | PROTEIN (MODE), NICKEL (II) ION | | Authors: | Hall, D.R., Gourley, D.G., Hunter, W.N. | | Deposit date: | 1999-02-12 | | Release date: | 2000-03-15 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The high-resolution crystal structure of the molybdate-dependent transcriptional regulator (ModE) from Escherichia coli: a novel combination of domain folds.
EMBO J., 18, 1999
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1B9N | | REGULATOR FROM ESCHERICHIA COLI | | Descriptor: | PROTEIN (MODE), NICKEL (II) ION | | Authors: | Hall, D.R., Gourley, D.G., Hunter, W.N. | | Deposit date: | 1999-02-12 | | Release date: | 2000-03-15 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | The high-resolution crystal structure of the molybdate-dependent transcriptional regulator (ModE) from Escherichia coli: a novel combination of domain folds.
EMBO J., 18, 1999
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1H47 | | STRUCTURES OF MECP SYNTHASE IN COMPLEX WITH (I) CMP AND (II) CMP AND PRODUCT | | Descriptor: | 2C-METHYL-D-ERYTHRITOL-2,4-CYCLODIPHOSPHATE SYNTHASE, GERANYL DIPHOSPHATE, ZINC ION, ... | | Authors: | Kemp, L.E., Alphey, M.S., Bond, C.S., Hunter, W.N. | | Deposit date: | 2003-02-24 | | Release date: | 2004-10-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | The Identification of Isoprenoids that Bind in the Intersubunit Cavity of Escherichia Coli 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase by Complementary Biophysical Methods
Acta Crystallogr.,Sect.D, 61, 2005
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1O7U | | RADIATION INDUCED TRYPAREDOXIN-I | | Descriptor: | TRYPAREDOXIN | | Authors: | Alphey, M.S., Bond, C.S., McSweeney, S.M., Hunter, W.N. | | Deposit date: | 2002-11-14 | | Release date: | 2003-04-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
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1O85 | | RADIATION-REDUCED TRYPAREDOXIN-I | | Descriptor: | TRYPAREDOXIN | | Authors: | Alphey, M.S., Bond, C.S., Hunter, W.N. | | Deposit date: | 2002-11-25 | | Release date: | 2003-04-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
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1O8W | | RADIATION-REDUCED TRYPAREDOXIN-I | | Descriptor: | TRYPAREDOXIN | | Authors: | Alphey, M.S., Bond, C.S., Hunter, W.N. | | Deposit date: | 2002-12-09 | | Release date: | 2003-08-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
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1O8X | | MUTANT TRYPAREDOXIN-I CYS43ALA | | Descriptor: | TRYPAREDOXIN | | Authors: | Alphey, M.S., Bond, C.S., Hunter, W.N. | | Deposit date: | 2002-12-09 | | Release date: | 2003-04-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
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1ZEN | | CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE | | Descriptor: | CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE, ZINC ION | | Authors: | Cooper, S.J., Leonard, G.A., Hunter, W.N. | | Deposit date: | 1996-07-08 | | Release date: | 1997-07-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The crystal structure of a class II fructose-1,6-bisphosphate aldolase shows a novel binuclear metal-binding active site embedded in a familiar fold.
Structure, 4, 1996
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2BNM | |
2BNN | |
2BNO | | THE STRUCTURE OF HYDROXYPROPYLPHOSPHONIC ACID EPOXIDASE FROM S. WEDMORENIS. | | Descriptor: | EPOXIDASE, MERCURY (II) ION, ZINC ION, ... | | Authors: | McLuskey, K., Cameron, S., Hunter, W.N. | | Deposit date: | 2005-03-29 | | Release date: | 2005-10-05 | | Last modified: | 2017-06-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure and Reactivity of Hydroxypropylphosphonic Acid Epoxidase in Fosfomycin Biosynthesis by a Cation- and Flavin-Dependent Mechanism.
Proc.Natl.Acad.Sci.USA, 102, 2005
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2HKE | |
