Aplysia californica AChBP in complex with a cytisine derivative

This is a large structure.

Summary for 6T9R

DescriptorAcetylcholine binding protein, (1~{R},9~{S})-5-(3-oxidanylpropyl)-7,11-diazatricyclo[^{2,7}]trideca-2,4-dien-6-one, N-ACETYL-D-GLUCOSAMINE, ... (8 entities in total)
Functional Keywordsacetylcholine binding protein, nicotinic receptor surrogate, hydrolase
Biological sourceAplysia californica (California sea hare)
Total number of polymer chains10
Total molecular weight293433.86
Davis, S.,Hunter, W.N. (deposition date: 2019-10-28, release date: 2020-02-12, Last modification date: 2020-02-19)
Primary citation
Davis, S.,Rego Campello, H.,Gallagher, T.,Hunter, W.N.
The thermodynamic profile and molecular interactions of a C(9)-cytisine derivative-binding acetylcholine-binding protein from Aplysia californica.
Acta Crystallogr.,Sect.F, 76:74-80, 2020
PubMed: 32039888 (PDB entries with the same primary citation)
DOI: 10.1107/S2053230X20001168
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20230 2.2% 1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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