Author results

1CLE
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STRUCTURE OF UNCOMPLEXED AND LINOLEATE-BOUND CANDIDA CYLINDRACEA CHOLESTEROL ESTERASE
Descriptor:CHOLESTEROL ESTERASE, N-ACETYL-D-GLUCOSAMINE, PHOSPHATE ION, ...
Authors:Ghosh, D.
Deposit date:1995-02-08
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of uncomplexed and linoleate-bound Candida cylindracea cholesterol esterase.
Structure, 3, 1995
1BHS
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HUMAN ESTROGENIC 17BETA-HYDROXYSTEROID DEHYDROGENASE
Descriptor:17BETA-HYDROXYSTEROID DEHYDROGENASE
Authors:Ghosh, D.
Deposit date:1995-04-19
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase at 2.20 A resolution.
Structure, 3, 1995
1G66
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ACETYLXYLAN ESTERASE AT 0.90 ANGSTROM RESOLUTION
Descriptor:ACETYL XYLAN ESTERASE II, SULFATE ION, GLYCEROL
Authors:Ghosh, D., Sawicki, M., Lala, P., Erman, M., Pangborn, W., Eyzaguirre, J., Gutierrez, R., Jornvall, H., Thiel, D.J.
Deposit date:2000-11-03
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Multiple conformations of catalytic serine and histidine in acetylxylan esterase at 0.90 A.
J.Biol.Chem., 276, 2001
1HDC
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MECHANISM OF INHIBITION OF 3ALPHA,20BETA-HYDROXYSTEROID DEHYDROGENASE BY A LICORICE-DERIVED STEROIDAL INHIBITOR
Descriptor:3-ALPHA, 20 BETA-HYDROXYSTEROID DEHYDROGENASE, CARBENOXOLONE
Authors:Ghosh, D.
Deposit date:1994-10-21
Release date:1995-02-07
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of inhibition of 3 alpha, 20 beta-hydroxysteroid dehydrogenase by a licorice-derived steroidal inhibitor.
Structure, 2, 1994
1N5D
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CRYSTAL STRUCTURE OF PORCINE TESTICULAR CARBONYL REDUCTASE/ 20BETA-HYDROXYSTEROID DEHYDROGENASE
Descriptor:CARBONYL REDUCTASE/20BETA-HYDROXYSTEROID DEHYDROGENASE, SULFATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Ghosh, D.
Deposit date:2002-11-05
Release date:2002-11-13
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Porcine Carbonyl Reductase: Structural Basis for a Functional Monomer in Short-Chain Dehydrogenases/Reductases
J.Biol.Chem., 276, 2001
2HSD
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THE REFINED THREE-DIMENSIONAL STRUCTURE OF 3ALPHA,20BETA-HYDROXYSTEROID DEHYDROGENASE AND POSSIBLE ROLES OF THE RESIDUES CONSERVED IN SHORT-CHAIN DEHYDROGENASES
Descriptor:3-ALPHA, 20 BETA-HYDROXYSTEROID DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Ghosh, D., Duax, W.L.
Deposit date:1994-03-28
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:The refined three-dimensional structure of 3 alpha,20 beta-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases.
Structure, 2, 1994
3S79
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HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1) REFINED AT 2.75 ANGSTROM
Descriptor:Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE, 4-ANDROSTENE-3-17-DIONE, ...
Authors:Ghosh, D.
Deposit date:2011-05-26
Release date:2012-06-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55, 2012
3S7S
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CRYSTAL STRUCTURE OF HUMAN PLACENTAL AROMATASE COMPLEXED WITH BREAST CANCER DRUG EXEMESTANE
Descriptor:Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE, (8alpha,10alpha,13alpha)-6-methylideneandrosta-1,4-diene-3,17-dione
Authors:Ghosh, D.
Deposit date:2011-05-26
Release date:2012-06-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55, 2012
4GL5
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STRUCTURE OF HUMAN PLACENTAL AROMATASE COMPLEXED WITH DESIGNED INHIBITOR HDDG029 (COMPOUND 4)
Descriptor:Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE, (6alpha,8alpha)-6-(but-2-yn-1-yloxy)androsta-1,4-diene-3,17-dione
Authors:Ghosh, D.
Deposit date:2012-08-13
Release date:2012-09-12
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55, 2012
4GL7
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STRUCTURE OF HUMAN PLACENTAL AROMATASE COMPLEXED WITH DESIGNED INHIBITOR HDDG046 (COMPOUND 5)
Descriptor:Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE, (6alpha,8alpha)-6-(pent-2-yn-1-yloxy)androsta-1,4-diene-3,17-dione
Authors:Ghosh, D.
Deposit date:2012-08-13
Release date:2012-09-12
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55, 2012
1BS9
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ACETYLXYLAN ESTERASE FROM P. PURPUROGENUM REFINED AT 1.10 ANGSTROMS
Descriptor:ACETYL XYLAN ESTERASE, SULFATE ION
Authors:Ghosh, D., Erman, M., Sawicki, M.W., Lala, P., Weeks, D.R., Li, N., Pangborn, W., Thiel, D.J., Jornvall, H., Eyzaguirre, J.
Deposit date:1998-09-01
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Determination of a protein structure by iodination: the structure of iodinated acetylxylan esterase.
Acta Crystallogr.,Sect.D, 55, 1999
2AXE
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IODINATED COMPLEX OF ACETYL XYLAN ESTERASE AT 1.80 ANGSTROMS
Descriptor:ACETYL XYLAN ESTERASE, SULFATE ION
Authors:Ghosh, D., Erman, M., Sawicki, M.W., Lala, P., Weeks, D.R., Li, N., Pangborn, W., Thiel, D.J., Jornvall, H., Eyzaguirre, J.
Deposit date:1998-09-01
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Determination of a protein structure by iodination: the structure of iodinated acetylxylan esterase.
Acta Crystallogr.,Sect.D, 55, 1999
3EQM
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CRYSTAL STRUCTURE OF HUMAN PLACENTAL AROMATASE CYTOCHROME P450 IN COMPLEX WITH ANDROSTENEDIONE
Descriptor:Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE, 4-ANDROSTENE-3-17-DIONE, ...
Authors:Ghosh, D.
Deposit date:2008-10-01
Release date:2008-12-23
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for androgen specificity and oestrogen synthesis in human aromatase.
Nature, 457, 2009
4LUR
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CRYSTAL STRUCTURE OF ZEBRAFISH INTERPHOTORECEPTOR RETINOID-BINDING PROTEIN (IRBP) MODULE 1
Descriptor:Interphotoreceptor Retinoid-Binding Protein(IRBP), 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
Authors:Ghosh, D., Gonzalez-Fernandez, F.
Deposit date:2013-07-25
Release date:2014-12-10
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Zebrafish IRBP Reveals Its Fatty Acid Binding Sites and Retention of Protease Fold
To be Published
5JKV
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HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1) AT 2.75 ANGSTROM WITH BOUND POLYETHYLENE GLYCOL
Descriptor:Aromatase, PROTOPORPHYRIN IX CONTAINING FE, 4-ANDROSTENE-3-17-DIONE, ...
Authors:Ghosh, D., Lo, J., Egbuta, C.
Deposit date:2016-04-26
Release date:2017-04-26
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Testosterone complex and non-steroidal ligands of human aromatase.
J. Steroid Biochem. Mol. Biol., 2018
5JKW
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HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1) COMPLEXED WITH TESTOSTERONE
Descriptor:Aromatase, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE
Authors:Ghosh, D., Egbuta, C., Lo, J.
Deposit date:2016-04-26
Release date:2017-04-26
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Testosterone complex and non-steroidal ligands of human aromatase.
J. Steroid Biochem. Mol. Biol., 2018
5JL6
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HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1): ANDROSTENEDIONE COMPLEX #2
Descriptor:Aromatase, PROTOPORPHYRIN IX CONTAINING FE, 4-ANDROSTENE-3-17-DIONE
Authors:Ghosh, D., Lo, J., Egbuta, C.
Deposit date:2016-04-26
Release date:2017-04-26
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Testosterone complex and non-steroidal ligands of human aromatase.
J. Steroid Biochem. Mol. Biol., 2018
5JL7
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HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1): ANDROSTENEDIONE COMPLEX #3
Descriptor:Aromatase, PROTOPORPHYRIN IX CONTAINING FE, 4-ANDROSTENE-3-17-DIONE
Authors:Ghosh, D., Lo, J., Egbuta, C.
Deposit date:2016-04-26
Release date:2017-04-26
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Testosterone complex and non-steroidal ligands of human aromatase.
J. Steroid Biochem. Mol. Biol., 2018
5JL9
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HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1): ANDROSTENEDIONE COMPLEX #4
Descriptor:Aromatase, PROTOPORPHYRIN IX CONTAINING FE, 4-ANDROSTENE-3-17-DIONE
Authors:Ghosh, D., Lo, J., Egbuta, C.
Deposit date:2016-04-26
Release date:2017-04-26
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Testosterone complex and non-steroidal ligands of human aromatase.
J. Steroid Biochem. Mol. Biol., 2018
1BK4
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CRYSTAL STRUCTURE OF RABBIT LIVER FRUCTOSE-1,6-BISPHOSPHATASE AT 2.3 ANGSTROM RESOLUTION
Descriptor:PROTEIN (FRUCTOSE-1,6-BISPHOSPHATASE), MAGNESIUM ION, SULFATE ION
Authors:Ghosh, D., Weeks, C.M., Erman, M., Roszak, A.W., Kaiser, R., Jornvall, H.
Deposit date:1998-07-14
Release date:1998-07-22
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of rabbit liver fructose 1,6-bisphosphatase at 2.3 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
2MC9
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CAT R 1
Descriptor:Peptidyl-prolyl cis-trans isomerase
Authors:Mueller, G., London, R., Ghosh, D.
Deposit date:2013-08-16
Release date:2014-06-25
Last modified:2014-10-08
Method:SOLUTION NMR
Cite:Primary identification, biochemical characterization, and immunologic properties of the allergenic pollen cyclophilin cat R 1.
J.Biol.Chem., 289, 2014
4KQ8
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STRUCTURE OF RECOMBINANT HUMAN CYTOCHROME P450 AROMATASE
Descriptor:Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE, 4-ANDROSTENE-3-17-DIONE, ...
Authors:Ghosh, D., Di Nardo, G., Griswold, J.
Deposit date:2013-05-14
Release date:2013-08-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Structural basis for the functional roles of critical residues in human cytochrome p450 aromatase.
Biochemistry, 52, 2013
1O76
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CYANIDE COMPLEX OF P450CAM FROM PSEUDOMONAS PUTIDA
Descriptor:CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ...
Authors:Fedorov, R., Ghosh, D., Schlichting, I.
Deposit date:2002-10-23
Release date:2002-12-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Cyanide Complexes of P450Cam and the Oxygenase Domain of Inducible Nitric Oxide Synthase-Structural Models of the Short-Lived Oxygen Complexes
Arch.Biochem.Biophys., 409, 2003
1EQU
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TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EQUILIN COMPLEXED WITH NADP+
Descriptor:PROTEIN (ESTRADIOL 17 BETA-DEHYDROGENASE 1), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, EQUILIN
Authors:Sawicki, M.W., Erman, M., Puranen, T., Vihko, P., Ghosh, D.
Deposit date:1998-12-02
Release date:1999-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+.
Proc.Natl.Acad.Sci.USA, 96, 1999
1KP6
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USTILAGO MAYDIS KILLER TOXIN KP6 ALPHA-SUBUNIT
Descriptor:PROTEIN (TOXIN), SULFATE ION
Authors:Li, N., Erman, M., Pangborn, W., Duax, W.L., Park, C.-M., Bruenn, J., Ghosh, D.
Deposit date:1999-05-28
Release date:1999-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Ustilago maydis killer toxin KP6 alpha-subunit. A multimeric assembly with a central pore.
J.Biol.Chem., 274, 1999
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