2QFB | | CRYSTAL STRUCTURE OF THE REGULATORY DOMAIN OF HUMAN RIG-I WITH BOUND ZN | | Descriptor: | Probable ATP-dependent RNA helicase DDX58, ZINC ION | | Authors: | Cui, S., Lammens, A., Lammens, K., Hopfner, K.P. | | Deposit date: | 2007-06-27 | | Release date: | 2008-02-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
Mol.Cell, 29, 2008
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2QFD | | CRYSTAL STRUCTURE OF THE REGULATORY DOMAIN OF HUMAN RIG-I WITH BOUND HG | | Descriptor: | Probable ATP-dependent RNA helicase DDX58, MERCURY (II) ION | | Authors: | Cui, S., Lammens, A., Lammens, K., Hopfner, K.P. | | Deposit date: | 2007-06-27 | | Release date: | 2008-02-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
Mol.Cell, 29, 2008
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3EIK | |
3OCI | | CRYSTAL STRUCTURE OF TBP (TATA BOX BINDING PROTEIN) | | Descriptor: | TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1), 1,2-ETHANEDIOL | | Authors: | Cui, S., Wollmann, P., Moldt, M., Hopfner, K.-P. | | Deposit date: | 2010-08-10 | | Release date: | 2011-07-13 | | Last modified: | 2015-01-14 | | Method: | X-RAY DIFFRACTION (1.899 Å) | | Cite: | Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.
Nature, 475, 2011
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3OSY | |
2W4R | | CRYSTAL STRUCTURE OF THE REGULATORY DOMAIN OF HUMAN LGP2 | | Descriptor: | PROBABLE ATP-DEPENDENT RNA HELICASE DHX58, MERCURY (II) ION, SULFATE ION | | Authors: | Pippig, D.A., Hellmuth, J.C., Cui, S., Kirchhofer, A., Lammens, K., Lammens, A., Schmidt, A., Rothenfusser, S., Hopfner, K.P. | | Deposit date: | 2008-12-01 | | Release date: | 2009-02-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA.
Nucleic Acids Res., 37, 2009
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3G9A | | GREEN FLUORESCENT PROTEIN BOUND TO MINIMIZER NANOBODY | | Descriptor: | Green fluorescent protein, Minimizer | | Authors: | Kirchhofer, A., Helma, J., Schmidthals, K., Frauer, C., Cui, S., Karcher, A., Pellis, M., Muyldermans, S., Delucci, C.C., Cardoso, M.C., Leonhardt, H., Hopfner, K.-P., Rothbauer, U. | | Deposit date: | 2009-02-13 | | Release date: | 2009-12-08 | | Last modified: | 2013-09-18 | | Method: | X-RAY DIFFRACTION (1.614 Å) | | Cite: | Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
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3K1K | | GREEN FLUORESCENT PROTEIN BOUND TO ENHANCER NANOBODY | | Descriptor: | Green Fluorescent Protein, Enhancer | | Authors: | Kirchhofer, A., Helma, J., Schmidthals, K., Frauer, C., Cui, S., Karcher, A., Pellis, M., Muyldermans, S., Delucci, C.C., Cardoso, M.C., Leonhardt, H., Hopfner, K.-P., Rothbauer, U. | | Deposit date: | 2009-09-28 | | Release date: | 2009-12-08 | | Last modified: | 2017-01-25 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
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3VGX | | STRUCTURE OF GP41 T21/CP621-652 | | Descriptor: | Envelope glycoprotein gp160, ACETIC ACID, GLYCEROL | | Authors: | Yao, X., Waltersperger, S., Wang, M., Cui, S. | | Deposit date: | 2011-08-22 | | Release date: | 2012-04-25 | | Last modified: | 2013-06-26 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Discovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652.
J.Biol.Chem., 287, 2012
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3VGY | | STRUCTURE OF HIV-1 GP41 NHR/FUSION INHIBITOR COMPLEX P321 | | Descriptor: | Envelope glycoprotein gp160, CP32M, SULFATE ION | | Authors: | Yao, X., Waltersperger, S., Wang, M.T., Cui, S. | | Deposit date: | 2011-08-22 | | Release date: | 2012-06-13 | | Last modified: | 2013-06-26 | | Method: | X-RAY DIFFRACTION (2.034 Å) | | Cite: | Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
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3VH7 | | STRUCTURE OF HIV-1 GP41 NHR/FUSION INHIBITOR COMPLEX P21 | | Descriptor: | Envelope glycoprotein gp160, CP32M, MAGNESIUM ION | | Authors: | Yao, X., Waltersperger, S., Wang, M.T., Cui, S. | | Deposit date: | 2011-08-23 | | Release date: | 2012-06-13 | | Last modified: | 2013-06-26 | | Method: | X-RAY DIFFRACTION (2.019 Å) | | Cite: | Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
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3VIE | | HIV-GP41 FUSION INHIBITOR SIFUVIRTIDE | | Descriptor: | Envelope glycoprotein gp160, Sifuvirtide | | Authors: | Yao, X., Waltersperger, S., Wang, M.T., Cui, S. | | Deposit date: | 2011-09-29 | | Release date: | 2012-01-18 | | Last modified: | 2013-07-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Broad antiviral activity and crystal structure of HIV-1 fusion inhibitor sifuvirtide
J.Biol.Chem., 287, 2012
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3VTP | |
3VTQ | |
3VU5 | | SHORT PEPTIDE HIV ENTRY INHIBITOR SC22EK | | Descriptor: | Transmembrane protein gp41, SC22, SULFATE ION, ... | | Authors: | Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S. | | Deposit date: | 2012-06-19 | | Release date: | 2012-12-19 | | Last modified: | 2013-07-24 | | Method: | X-RAY DIFFRACTION (2.087 Å) | | Cite: | Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
Faseb J., 27, 2013
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3VU6 | | SHORT PEPTIDE HIV ENTRY INHIBITOR MT-SC22EK WITH A M-T HOOK | | Descriptor: | Transmembrane protein gp41, MTSC22, SULFATE ION | | Authors: | Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S. | | Deposit date: | 2012-06-19 | | Release date: | 2012-12-19 | | Last modified: | 2013-07-24 | | Method: | X-RAY DIFFRACTION (2.324 Å) | | Cite: | Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
Faseb J., 27, 2013
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3VWB | | CRYSTAL STRUCTURE OF VIRB CORE DOMAIN (SE-MET DERIVATIVE) COMPLEXED WITH THE CIS-ACTING SITE (5-BRU MODIFICATIONS) UPSTREAM ICSB PROMOTER | | Descriptor: | Virulence regulon transcriptional activator virB, DNA (26-MER) | | Authors: | Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S. | | Deposit date: | 2012-08-21 | | Release date: | 2013-08-21 | | Last modified: | 2013-12-25 | | Method: | X-RAY DIFFRACTION (2.416 Å) | | Cite: | Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
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3W19 | |
3W2A | | CRYSTAL STRUCTURE OF VIRB CORE DOMAIN COMPLEXED WITH THE CIS-ACTING SITE UPSTREAM ICSP PROMOTER | | Descriptor: | Virulence regulon transcriptional activator VirB, DNA (31-mer) | | Authors: | Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S. | | Deposit date: | 2012-11-27 | | Release date: | 2013-09-04 | | Last modified: | 2013-12-25 | | Method: | X-RAY DIFFRACTION (2.775 Å) | | Cite: | Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
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3W3C | | CRYSTAL STRUCTURE OF VIRB CORE DOMAIN COMPLEXED WITH THE CIS-ACTING SITE UPSTREAM ICSB PROMOTER | | Descriptor: | Virulence regulon transcriptional activator VirB, DNA (26-MER) | | Authors: | Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S. | | Deposit date: | 2012-12-19 | | Release date: | 2013-09-04 | | Last modified: | 2013-12-25 | | Method: | X-RAY DIFFRACTION (2.431 Å) | | Cite: | Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
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4I2L | | NEW HIV ENTRY INHIBITOR MTSFT/T23 COMPLEX | | Descriptor: | GP41, inhibitor MTSFT | | Authors: | Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S. | | Deposit date: | 2012-11-22 | | Release date: | 2014-01-22 | | Method: | X-RAY DIFFRACTION (1.426 Å) | | Cite: | Potent antiviral activity of the novel HIV entry inhibitor MTSFT
To be Published
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5GMQ | | STRUCTURE OF MERS-COV RBD IN COMPLEX WITH A FULLY HUMAN ANTIBODY MCA1 | | Descriptor: | S protein, MCA1 heavy chain, MCA1 light chain, ... | | Authors: | Chen, C., Wang, J.M., Zou, T.T., Gao, X.P., Cui, S., Jin, Q. | | Deposit date: | 2016-07-15 | | Release date: | 2017-05-31 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset.
J. Infect. Dis., 215, 2017
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3OC3 | | CRYSTAL STRUCTURE OF THE MOT1 N-TERMINAL DOMAIN IN COMPLEX WITH TBP | | Descriptor: | HELICASE MOT1, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | | Authors: | Wollmann, P., Cui, S., Viswanathan, R., Berninghausen, O., Wells, M.N., Moldt, M., Witte, G., Butryn, A., Wendler, P., Beckmann, R., Auble, D.T., Hopfner, K.-P. | | Deposit date: | 2010-08-09 | | Release date: | 2011-07-13 | | Last modified: | 2011-07-27 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.
Nature, 475, 2011
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3QZQ | | HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT E71D IN COMPLEX WITH RUPINTRIVIR | | Descriptor: | 3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | Authors: | Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S. | | Deposit date: | 2011-03-07 | | Release date: | 2011-08-10 | | Last modified: | 2015-05-06 | | Method: | X-RAY DIFFRACTION (1.7001 Å) | | Cite: | Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
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3QZR | | HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT E71A IN COMPLEX WITH RUPINTRIVIR | | Descriptor: | 3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, 1,2-ETHANEDIOL | | Authors: | Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S. | | Deposit date: | 2011-03-07 | | Release date: | 2011-08-10 | | Last modified: | 2015-05-06 | | Method: | X-RAY DIFFRACTION (1.039 Å) | | Cite: | Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
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