Author results

1HC8
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CRYSTAL STRUCTURE OF A CONSERVED RIBOSOMAL PROTEIN-RNA COMPLEX
Descriptor:RIBOSOMAL PROTEIN L11, 58 NUCLEOTIDE RIBOSOMAL 23S RNA DOMAIN, MAGNESIUM ION, ...
Authors:Conn, G.L., Draper, D.E., Lattman, E.E., Gittis, A.G.
Deposit date:2001-04-27
Release date:2002-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Compact RNA Tertiary Structure Contains a Buried Backbone-K+ Complex
J.Mol.Biol., 318, 2002
1QA6
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CRYSTAL STRUCTURE OF A CONSERVED RIBOSOMAL PROTEIN-RNA COMPLEX
Descriptor:58 NUCLEOTIDE RIBOSOMAL RNA DOMAIN, RIBOSOMAL PROTEIN L11, MAGNESIUM ION, ...
Authors:Conn, G.L., Draper, D.E., Lattman, E.E., Gittis, A.G.
Deposit date:1999-04-15
Release date:1999-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a conserved ribosomal protein-RNA complex.
Science, 284, 1999
1OO7
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DNA.RNA HYBRID DUPLEX CONTAINING A 5-PROPYNE DNA STRAND AND PURINE-RICH RNA STRAND, NMR, 4 STRUCTURES
Descriptor:5'-R(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3', 5'-D(*GP*(5PC)P*(PDU)P*(PDU)P*(5PC)P*(PDU)P*(5PC)P*(PDU)P*(PDU)P*C)-3'
Authors:Gyi, J.I., Gao, D., Conn, G.L., Trent, J.O., Brown, T., Lane, A.N.
Deposit date:2003-03-03
Release date:2003-11-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of a DNA*RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications
Nucleic Acids Res., 31, 2003
1AL5
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A-TRACT RNA DODECAMER, NMR, 12 STRUCTURES
Descriptor:RNA (5'-R(*CP*GP*CP*AP*AP*AP*UP*UP*UP*GP*CP*G)-3')
Authors:Conte, M.R., Conn, G.L., Brown, T., Lane, A.N.
Deposit date:1997-06-11
Release date:1997-12-17
Last modified:2018-03-14
Method:SOLUTION NMR
Cite:Conformational properties and thermodynamics of the RNA duplex r(CGCAAAUUUGCG)2: comparison with the DNA analogue d(CGCAAATTTGCG)2.
Nucleic Acids Res., 25, 1997
1AXP
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DNA DUPLEX CONTAINING A PURINE-RICH STRAND, NMR, 6 STRUCTURES
Descriptor:DNA (D(GAAGAGAAGC)(DOT)D(GCTTCTCTTC))
Authors:Gyi, J.I., Lane, A.N., Conn, G.L., Brown, T.
Deposit date:1997-10-17
Release date:1998-04-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes.
Biochemistry, 37, 1998
1DRR
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DNA/RNA HYBRID DUPLEX CONTAINING A PURINE-RICH DNA STRAND, NMR, 10 STRUCTURES
Descriptor:DNA (5'-D(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3'), RNA (5'-R(*GP*CP*UP*UP*CP*UP*CP*UP*UP*C)-3')
Authors:Gyi, J.I., Lane, A.N., Conn, G.L., Brown, T.
Deposit date:1997-10-21
Release date:1998-04-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes.
Biochemistry, 37, 1998
1RRD
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DNA/RNA HYBRID DUPLEX CONTAINING A PURINE-RICH RNA STRAND, NMR, 10 STRUCTURES
Descriptor:RNA (5'-R(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*TP*CP*TP*CP*TP*TP*C)-3')
Authors:Gyi, J.I., Lane, A.N., Conn, G.L., Brown, T.
Deposit date:1997-10-21
Release date:1998-04-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes.
Biochemistry, 37, 1998
1RRR
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RNA DUPLEX CONTAINING A PURINE-RICH STRAND, NMR, 10 STRUCTURES
Descriptor:RNA (5'-R(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3'), RNA (5'-R(*GP*CP*UP*UP*CP*UP*CP*UP*UP*C)-3')
Authors:Gyi, J.I., Lane, A.N., Conn, G.L., Brown, T.
Deposit date:1997-10-21
Release date:1998-04-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes.
Biochemistry, 37, 1998
1Y39
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CO-EVOLUTION OF PROTEIN AND RNA STRUCTURES WITHIN A HIGHLY CONSERVED RIBOSOMAL DOMAIN
Descriptor:58 Nucleotide Ribosomal 23S RNA Domain, 50S ribosomal protein L11, COBALT (III) ION, ...
Authors:Dunstan, M.S., GuhaThakurta, D., Draper, D.E., Conn, G.L.
Deposit date:2004-11-24
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Coevolution of Protein and RNA Structures within a Highly Conserved Ribosomal Domain
Chem.Biol., 12, 2005
2O9U
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MONELLIN (MNEI) AT 1.15 RESOLUTION
Descriptor:Monellin chain B and Monellin chain A, SULFATE ION
Authors:Hobbs, J.R., Munger, S.D., Conn, G.L.
Deposit date:2006-12-14
Release date:2007-02-20
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Monellin (MNEI) at 1.15 A resolution
Acta Crystallogr.,Sect.F, 63, 2007
3GYQ
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STRUCTURE OF THE THIOSTREPTON-RESISTANCE METHYLTRANSFERASE S-ADENOSYL-L-METHIONINE COMPLEX
Descriptor:rRNA (adenosine-2'-O-)-methyltransferase, S-ADENOSYLMETHIONINE
Authors:Dunstan, M.S., Conn, G.L.
Deposit date:2009-04-04
Release date:2009-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of the thiostrepton-resistance methyltransferase-S-adenosyl-L-methionine complex and its interaction with ribosomal RNA
J.Biol.Chem., 284, 2009
3MTE
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CRYSTAL STRUCTURE OF 16S RRNA METHYLTRANFERASE
Descriptor:16S rRNA methylase, S-ADENOSYLMETHIONINE
Authors:Macmaster, R.A., Conn, G.L., Zelinskaya, N.
Deposit date:2010-04-30
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria.
Nucleic Acids Res., 38, 2010
3PXM
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REDUCED SWEETNESS OF A MONELLIN (MNEI) MUTANT RESULTS FROM INCREASED PROTEIN FLEXIBILITY AND DISRUPTION OF A DISTANT POLY-(L-PROLINE) II HELIX
Descriptor:Monellin chain B/Monellin chain A chimeric protein
Authors:Hobbs, J.R., Templeton, C.M., Pour, S.O., Blanch, E.W., Munger, S.M., Conn, G.L.
Deposit date:2010-12-10
Release date:2011-04-06
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Reduced Sweetness of a Monellin (MNEI) Mutant Results from Increased Protein Flexibility and Disruption of a Distant Poly-(L-Proline) II Helix.
Chem Senses, 36, 2011
3Q2P
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REDUCED SWEETNESS OF A MONELLIN (MNEI) MUTANT RESULTS FROM INCREASED PROTEIN FLEXIBILITY AND DISRUPTION OF A DISTANT POLY-(L-PROLINE) II HELIX
Descriptor:Monellin chain B/Monellin chain A chimeric protein, SODIUM ION
Authors:Templeton, C.M., Hobbs, J.R., Munger, S.D., Conn, G.L.
Deposit date:2010-12-20
Release date:2011-04-06
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.341 Å)
Cite:Reduced Sweetness of a Monellin (MNEI) Mutant Results from Increased Protein Flexibility and Disruption of a Distant Poly-(L-Proline) II Helix.
Chem Senses, 36, 2011
4OX9
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CRYSTAL STRUCTURE OF THE AMINOGLYCOSIDE RESISTANCE METHYLTRANSFERASE NPMA BOUND TO THE 30S RIBOSOMAL SUBUNIT
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Dunkle, J.A., Conn, G.L., Dunham, C.M.
Deposit date:2014-02-04
Release date:2014-04-09
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (3.8035 Å)
Cite:Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.
Proc.Natl.Acad.Sci.USA, 111, 2014
4X1O
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CRYSTAL STRUCTURE OF THE 16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE FROM CATENULISPORALES ACIDIPHILIA
Descriptor:16S rRNA (adenine(1408)-N(1))-methyltransferase
Authors:Witek, M.A., Conn, G.L.
Deposit date:2014-11-25
Release date:2015-11-04
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
Nucleic Acids Res., 44, 2016
5BW4
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CRYSTAL STRUCTURE OF THE 16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE W203A MUTANT WITH COSUBSTRATE SAM FROM CATENULISPORALES ACIDIPHILIA
Descriptor:16S rRNA (adenine(1408)-N(1))-methyltransferase, S-ADENOSYLMETHIONINE
Authors:Witek, M.A., Conn, G.L.
Deposit date:2015-06-05
Release date:2016-04-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
Nucleic Acids Res., 44, 2016
5BW5
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CRYSTAL STRUCTURE OF THE 16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE D21A MUTANT FROM CATENULISPORALES ACIDIPHILIA
Descriptor:16S rRNA (adenine(1408)-N(1))-methyltransferase
Authors:Witek, M.A., Conn, G.L.
Deposit date:2015-06-05
Release date:2016-04-20
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
Nucleic Acids Res., 44, 2016
5D1H
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CRYSTAL STRUCTURE OF THE 16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE W203A MUTANT FROM CATENULISPORALES ACIDIPHILIA
Descriptor:Uncharacterized protein
Authors:Witek, M.A., Conn, G.L.
Deposit date:2015-08-04
Release date:2016-04-20
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
Nucleic Acids Res., 44, 2016
5D1N
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CRYSTAL STRUCTURE OF THE 16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE WITH ITS REACTION BY-PRODUCT SAH FROM CATENULISPORALES ACIDIPHILIA
Descriptor:Uncharacterized protein, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Witek, M.A., Conn, G.L.
Deposit date:2015-08-04
Release date:2016-04-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.713 Å)
Cite:Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
Nucleic Acids Res., 44, 2016
5EOV
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C-TERMINAL DOMAIN OF THE 16S/23S RRNA (CYTIDINE-2'-O)-METHYLTRANSFERASE TLYA.
Descriptor:16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA
Authors:Witek, M.A., Conn, G.L.
Deposit date:2015-11-10
Release date:2016-11-23
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:A Novel Motif for S-Adenosyl-l-methionine Binding by the Ribosomal RNA Methyltransferase TlyA from Mycobacterium tuberculosis.
J. Biol. Chem., 292, 2017
5KS2
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RAWV_CTD (HELIX FORM) OF 16S/23S 2'-O-METHYLTRANSFERASE TLYA
Descriptor:16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA, CHLORIDE ION
Authors:Kuiper, E.G., Conn, G.L.
Deposit date:2016-07-07
Release date:2017-01-04
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:A Novel Motif for S-Adenosyl-l-methionine Binding by the Ribosomal RNA Methyltransferase TlyA from Mycobacterium tuberculosis.
J. Biol. Chem., 292, 2017
5KYG
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RAWV_CTD (LOOP STRUCTURE) OF 16S/23S 2'-O-METHYLTRANSFERASE TLYA
Descriptor:Cytotoxin / haemolysin homologue TlyA, GLYCEROL
Authors:Kuiper, E.G., Conn, G.L.
Deposit date:2016-07-21
Release date:2017-01-04
Last modified:2017-02-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Novel Motif for S-Adenosyl-l-methionine Binding by the Ribosomal RNA Methyltransferase TlyA from Mycobacterium tuberculosis.
J. Biol. Chem., 292, 2017
404D
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CRYSTAL STRUCTURE OF THE RNA/DNA HYBRID R(GAAGAGAAGC). D(GCTTCTCTTC)
Descriptor:5'-R(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*CP*TP*CP*TP*TP*C)-3'
Authors:Conn, G., Brown, T., Leonard, G.A.
Deposit date:1998-06-12
Release date:1998-12-14
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) shows significant differences to that found in solution.
Nucleic Acids Res., 27, 1999
3PYJ
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REDUCED SWEETNESS OF A MONELLIN (MNEI) MUTANT RESULTS FROM INCREASED PROTEIN FLEXIBILITY AND DISRUPTION OF A DISTANT POLY-(L-PROLINE) II HELIX
Descriptor:Monellin chain B/Monellin chain A chimeric protein, FORMIC ACID
Authors:Hobbs, J.R., Conn, G.C., Munger, S.D., Templeton, C.M.
Deposit date:2010-12-13
Release date:2011-04-06
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Reduced Sweetness of a Monellin (MNEI) Mutant Results from Increased Protein Flexibility and Disruption of a Distant Poly-(L-Proline) II Helix.
Chem Senses, 36, 2011
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