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6QL5
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STRUCTURE OF FATTY ACID SYNTHASE COMPLEX WITH BOUND GAMMA SUBUNIT FROM SACCHAROMYCES CEREVISIAE AT 2.8 ANGSTROM
Descriptor:Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, Translation machinery-associated protein 17, ...
Authors:Singh, K., Graf, B., Linden, A., Sautner, V., Urlaub, H., Tittmann, K., Stark, H., Chari, A.
Deposit date:2019-01-31
Release date:2020-03-18
Last modified:2020-04-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL6
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STRUCTURE OF FATTY ACID SYNTHASE COMPLEX FROM SACCHAROMYCES CEREVISIAE AT 2.9 ANGSTROM
Descriptor:Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, [(3~{R})-4-azanyl-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] dihydrogen phosphate, ...
Authors:Singh, K., Graf, B., Linden, A., Sautner, V., Urlaub, H., Tittmann, K., Stark, H., Chari, A.
Deposit date:2019-01-31
Release date:2020-03-18
Last modified:2020-04-08
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL7
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STRUCTURE OF FATTY ACID SYNTHASE COMPLEX WITH BOUND GAMMA SUBUNIT FROM SACCHAROMYCES CEREVISIAE AT 4.6 ANGSTROM
Descriptor:Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, Translation machinery-associated protein 17
Authors:Singh, K., Graf, B., Linden, A., Sautner, V., Urlaub, H., Tittmann, K., Stark, H., Chari, A.
Deposit date:2019-01-31
Release date:2020-03-18
Last modified:2020-04-08
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL9
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STRUCTURE OF FATTY ACID SYNTHASE COMPLEX FROM SACCHAROMYCES CEREVISIAE AT 2.9 ANGSTROM
Descriptor:Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, 4'-PHOSPHOPANTETHEINE, ...
Authors:Singh, K., Graf, B., Linden, A., Sautner, V., Urlaub, H., Tittmann, K., Stark, H., Chari, A.
Deposit date:2019-01-31
Release date:2020-03-18
Last modified:2020-04-08
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
5LE5
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NATIVE HUMAN 20S PROTEASOME AT 1.8 ANGSTROM
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Schrader, J., Henneberg, F., Mata, R., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A.
Deposit date:2016-06-29
Release date:2016-08-17
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Science, 353, 2016
5LEX
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NATIVE HUMAN 20S PROTEASOME IN MG-ACETATE AT 2.2 ANGSTROM
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Schrader, J., Henneberg, F., Mata, R., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A.
Deposit date:2016-06-30
Release date:2016-08-17
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Science, 353, 2016
5LEY
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HUMAN 20S PROTEASOME COMPLEX WITH OPROZOMIB AT 1.9 ANGSTROM
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Schrader, J., Henneberg, F., Mata, R., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A.
Deposit date:2016-06-30
Release date:2016-08-17
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Science, 353, 2016
5LEZ
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HUMAN 20S PROTEASOME COMPLEX WITH OPROZOMIB IN MG-ACETATE AT 2.2 ANGSTROM
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Schrader, J., Henneberg, F., Mata, R., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A.
Deposit date:2016-06-30
Release date:2016-08-17
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Science, 353, 2016
5LF0
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HUMAN 20S PROTEASOME COMPLEX WITH EPOXOMICIN AT 2.4 ANGSTROM
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Schrader, J., Henneberg, F., Mata, R., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A.
Deposit date:2016-06-30
Release date:2016-08-17
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Science, 353, 2016
5LF1
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HUMAN 20S PROTEASOME COMPLEX WITH DIHYDROEPONEMYCIN AT 2.0 ANGSTROM
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Schrader, J., Henneberg, F., Mata, R., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A.
Deposit date:2016-06-30
Release date:2016-08-17
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Science, 353, 2016
5LF3
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HUMAN 20S PROTEASOME COMPLEX WITH BORTEZOMIB AT 2.1 ANGSTROM
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Schrader, J., Henneberg, F., Mata, R., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A.
Deposit date:2016-06-30
Release date:2016-08-17
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Science, 353, 2016
5LF4
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HUMAN 20S PROTEASOME COMPLEX WITH DELANZOMIB AT 2.0 ANGSTROM
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Schrader, J., Henneberg, F., Mata, R., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A.
Deposit date:2016-06-30
Release date:2016-08-17
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Science, 353, 2016
5LF6
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HUMAN 20S PROTEASOME COMPLEX WITH Z-LLY-KETOALDEHYDE AT 2.1 ANGSTROM
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Schrader, J., Henneberg, F., Mata, R., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A.
Deposit date:2016-06-30
Release date:2016-08-17
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Science, 353, 2016
5LF7
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HUMAN 20S PROTEASOME COMPLEX WITH IXAZOMIB AT 2.0 ANGSTROM
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Schrader, J., Henneberg, F., Mata, R., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A.
Deposit date:2016-06-30
Release date:2016-08-17
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Science, 353, 2016
5M32
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HUMAN 26S PROTEASOME IN COMPLEX WITH OPROZOMIB
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Haselbach, D., Schrader, J., Lambrecht, F., Henneberg, F., Chari, A., Stark, H.
Deposit date:2016-10-14
Release date:2017-07-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs.
Nat Commun, 8, 2017
4F7U
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THE 6S SNRNP ASSEMBLY INTERMEDIATE
Descriptor:Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein E, ...
Authors:Grimm, C., Pelz, J.P.
Deposit date:2012-05-16
Release date:2013-01-30
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.898 Å)
Cite:Structural Basis of Assembly Chaperone- Mediated snRNP Formation.
Mol.Cell, 49, 2013
4NOX
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STRUCTURE OF THE NINE-BLADED BETA-PROPELLER OF EIF3B
Descriptor:Eukaryotic translation initiation factor 3 subunit B, CHLORIDE ION
Authors:Liu, Y., Neumann, P., Kuhle, B., Monecke, T., Ficner, R.
Deposit date:2013-11-20
Release date:2014-09-17
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2.722 Å)
Cite:Translation initiation factor eIF3b contains a nine-bladed beta-propeller and interacts with the 40S ribosomal subunit
Structure, 22, 2014
4V98
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THE 8S SNRNP ASSEMBLY INTERMEDIATE
Descriptor:Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein E, ...
Authors:Grimm, C., Pelz, J.P., Schindelin, H., Diederichs, K., Kuper, J., Kisker, C.
Deposit date:2012-05-15
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of Assembly Chaperone- Mediated snRNP Formation.
Mol.Cell, 49, 2013
5LQW
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YEAST ACTIVATED SPLICEOSOME
Descriptor:Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, Pre-mRNA-splicing helicase BRR2, ...
Authors:Rauhut, R., Luehrmann, R.
Deposit date:2016-08-17
Release date:2016-10-05
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
Science, 6306, 2016
6H55
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CORE OF THE HUMAN PYRUVATE DEHYDROGENASE (E2)
Descriptor:Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
Authors:Haselbach, D., Prajapati, S., Tittmann, K., Stark, H.
Deposit date:2018-07-23
Release date:2019-06-05
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters.
Structure, 27, 2019
6H60
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PSEUDO-ATOMIC STRUCTURAL MODEL OF THE E3BP COMPONENT OF THE HUMAN PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
Descriptor:Pyruvate dehydrogenase protein X component, mitochondrial
Authors:Haselbach, D., Prajapati, S., Tittmann, K., Stark, H.
Deposit date:2018-07-25
Release date:2019-06-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters.
Structure, 27, 2019