Author results

1N8O
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN BOVINE CHYMOTRYPSIN AND ECOTIN
Descriptor:Chymotrypsin A, A chain, b chain, ...
Authors:Cambillau, C., Spinelli, S., Lauwereys, M.
Deposit date:2002-11-21
Release date:2002-12-18
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a Complex Between Bovine Chymotrypsin and Ecotin at 2.0 A Resolution
To be Published
1U0Q
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STRUCTURE OF A LLAMA VHH DOMAIN RAISED AGAINST A CARBAZOLE MOLECULE
Descriptor:immunoglobulin heavy chain variable domain
Authors:Cambillau, C., Spinelli, S., Desmyter, A., Verrips, T.
Deposit date:2004-07-14
Release date:2005-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of a Llama VHH Domain Raised Against a Carbazole Hapten
TO BE PUBLISHED
5M38
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STRUCTURE OF THE TAGL PEPTIDOGLYCAN BINDING DOMAIN FROM EAEC T6SS
Descriptor:OmpA family protein
Authors:Cambillau, C., Nguyen, V.S., Spinelli, S., Cascales, E.
Deposit date:2016-10-14
Release date:2018-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the TagL peptidoglycan binding domain from EAEC T6SS
To Be Published
5M3G
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STRUCTURE OF THE TAGL PEPTIDOGLYCAN BINDING DOMAIN FROM EAEC T6SS
Descriptor:OmpA family protein, SULFATE ION, 2,6-DIAMINOPIMELIC ACID
Authors:Cambillau, C., Nguyen, V.S., Spinelli, S., Cascales, E.
Deposit date:2016-10-14
Release date:2018-02-21
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structure of the TagL peptidoglycan binding domain from EAEC T6SS in complex with Diaminopimelate
To Be Published
1FFA
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CONTRIBUTION OF CUTINASE SERINE 42 SIDE CHAIN TO THE STABILIZATION OF THE OXYANION TRANSITION STATE
Descriptor:CUTINASE
Authors:Cambillau, C., Martinez, C., Nicolas, A.
Deposit date:1995-10-07
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Contribution of cutinase serine 42 side chain to the stabilization of the oxyanion transition state.
Biochemistry, 35, 1996
1FFB
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CONTRIBUTION OF CUTINASE SERINE 42 SIDE CHAIN TO THE STABILIZATION OF THE OXYANION TRANSITION STATE
Descriptor:CUTINASE
Authors:Cambillau, C., Martinez, C., Nicolas, A.
Deposit date:1995-10-07
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Contribution of cutinase serine 42 side chain to the stabilization of the oxyanion transition state.
Biochemistry, 35, 1996
1FFC
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CONTRIBUTION OF CUTINASE SERINE 42 SIDE CHAIN TO THE STABILIZATION OF THE OXYANION TRANSITION STATE
Descriptor:CUTINASE
Authors:Cambillau, C., Martinez, C., Nicolas, A.
Deposit date:1995-10-07
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Contribution of cutinase serine 42 side chain to the stabilization of the oxyanion transition state.
Biochemistry, 35, 1996
1FFD
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CONTRIBUTION OF CUTINASE SERINE 42 SIDE CHAIN TO THE STABILIZATION OF THE OXYANION TRANSITION STATE
Descriptor:CUTINASE
Authors:Cambillau, C., Martinez, C., Nicolas, A.
Deposit date:1995-10-07
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Contribution of cutinase serine 42 side chain to the stabilization of the oxyanion transition state.
Biochemistry, 35, 1996
1FFE
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CONTRIBUTION OF CUTINASE SERINE 42 SIDE CHAIN TO THE STABILIZATION OF THE OXYANION TRANSITION STATE
Descriptor:CUTINASE
Authors:Cambillau, C., Martinez, C., Nicolas, A.
Deposit date:1995-10-07
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Contribution of cutinase serine 42 side chain to the stabilization of the oxyanion transition state.
Biochemistry, 35, 1996
5M2I
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STRUCTURE OF HUMAN TUMOR NECROSIS FACTOR (TNF) IN COMPLEX WITH THE LLAMA VHH1
Descriptor:Tumor necrosis factor, VHH1
Authors:Cambillau, C., Spinelli, S., Desmyter, A., de Haard, H.
Deposit date:2016-10-13
Release date:2017-08-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions.
Front Immunol, 8, 2017
5M2J
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COMPLEX BETWEEN HUMAN TNF ALPHA AND LLAMA VHH2
Descriptor:Tumor necrosis factor, Anti-(ED-B) scFV
Authors:Cambillau, C., Spinelli, S., Desmyter, A., de Haard, H.
Deposit date:2016-10-13
Release date:2017-08-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions.
Front Immunol, 8, 2017
5M2M
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COMPLEX BETWEEN HUMAN TNF ALPHA AND LLAMA VHH3
Descriptor:Tumor necrosis factor, Llama nanobody VHH3
Authors:Cambillau, C., Spinelli, S., Desmyter, A., de Haard, H.
Deposit date:2016-10-13
Release date:2017-08-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions.
Front Immunol, 8, 2017
5M2W
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STRUCTURE OF NANOBODY NB18 RAISED AGAINST TSSK FROM E. COLI T6SS
Descriptor:Llama nanobody nb8 against TssK from T6SS, SULFATE ION
Authors:Cambillau, C., Nguyen, V.S., Spinelli, S., Desmyter, A.
Deposit date:2016-10-13
Release date:2017-06-28
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
5M2Y
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STRUCTURE OF TSSK C-TERMINAL DOMAIN FROM E. COLI T6SS
Descriptor:TssK C
Authors:Cambillau, C., Nguyen, V.S., Spinelli, S., Desmyter, A., Legrand, P.
Deposit date:2016-10-13
Release date:2017-06-28
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
5MWN
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STRUCTURE OF THE EAEC T6SS COMPONENT TSSK N-TERMINAL DOMAIN IN COMPLEX WITH LLAMA NANOBODIES NBK18 AND NBK27
Descriptor:Type VI secretion protein, llama nanobody raised against TssK, nbK18, ...
Authors:Cambillau, C., Nguyen, V.S., Spinelli, S., Legrand, P.
Deposit date:2017-01-18
Release date:2017-06-28
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
6EYX
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ANTI-CRISPR ACRIIA6 TETRAGONAL FORM
Descriptor:AcrIIa6
Authors:Cambillau, C., Amigues, B., Moineau, S.
Deposit date:2017-11-13
Release date:2018-06-06
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins.
Nat Commun, 9, 2018
6EYY
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ANTI-CRISPR ACRIIA6 CUBIC FORM
Descriptor:AcrIIa6
Authors:Cambillau, C., Amigues, B., Moineau, S.
Deposit date:2017-11-13
Release date:2018-06-06
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins.
Nat Commun, 9, 2018
2A9M
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STRUCTURAL ANALYSIS OF A TIGHT-BINDING FLUORESCEIN-SCFV; APO FORM
Descriptor:fluorescein-scfv light chain, fluorescein-scfv heavy chain
Authors:Cambillau, C., Spinelli, S., Honegger, A., Pluckthun, A.
Deposit date:2005-07-12
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A mutation designed to alter crystal packing permits structural analysis of a tight-binding fluorescein-scFv complex.
Protein Sci., 14, 2005
2A9N
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A MUTATION DESIGNED TO ALTER CRYSTAL PACKING PERMITS STRUCTURAL ANALYSIS OF A TIGHT-BINDING FLUORESCEIN-SCFV COMPLEX
Descriptor:fluorescein-scfv light chain, fluorescein-scfv heavy chain, 4-(2,7-DIFLUORO-6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)ISOPHTHALIC ACID
Authors:Cambillau, C., Spinelli, S., Honegger, A., Pluckthun, A.
Deposit date:2005-07-12
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A mutation designed to alter crystal packing permits structural analysis of a tight-binding fluorescein-scFv complex.
Protein Sci., 14, 2005
2F0C
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STRUCTURE OF THE RECEPTOR BINDING PROTEIN (ORF49, BBP) FROM LACTOPHAGE TP901-1
Descriptor:Phage tp901-1 ORF49 (BPP), GLYCEROL
Authors:Cambillau, C., Spinelli, S.
Deposit date:2005-11-13
Release date:2006-03-28
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Modular structure of the receptor binding proteins of Lactococcus lactis phages. The RBP structure of the temperate phage TP901-1.
J.Biol.Chem., 281, 2006
5LY8
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STRUCTURE OF THE CBM2 MODULE OF LACTOBACILLUS CASEI BL23 PHAGE J-1 EVOLVED DIT.
Descriptor:Tail component, MAGNESIUM ION
Authors:Cambillau, C., Spinelli, S., Dieterle, M.-E., Piuri, M.
Deposit date:2016-09-26
Release date:2017-03-22
Last modified:2017-05-24
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Evolved distal tail carbohydrate binding modules of Lactobacillus phage J-1: a novel type of anti-receptor widespread among lactic acid bacteria phages.
Mol. Microbiol., 104, 2017
5NGH
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STRUCTURE OF ODORANT BINDING PROTEIN 3 FROM GIANT PANDA (AILUROPODA MELANOLEUCA)
Descriptor:Odorant Binding Protein 3, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Cambillau, C., Spinelli, S., Pelosi, P.
Deposit date:2017-03-17
Release date:2017-11-01
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Reverse chemical ecology: Olfactory proteins from the giant panda and their interactions with putative pheromones and bamboo volatiles.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NGI
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STRUCTURE OF XCPQN012
Descriptor:Type II secretion system protein D
Authors:Cambillau, C., Roussel, A., Trinh, T.N.
Deposit date:2017-03-17
Release date:2018-01-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain Provides New Molecular Insights into Type II Secretion System Secreton Architecture and Dynamics.
MBio, 8, 2017
6FVJ
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TESA A MAJOR THIOESTERASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Thioesterase, hexadecyl dihydrogen phosphate, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Cambillau, C., Nguyen, V.S., Canaan, S.
Deposit date:2018-03-03
Release date:2018-10-24
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Biochemical and Structural Characterization of TesA, a Major Thioesterase Required for Outer-Envelope Lipid Biosynthesis in Mycobacterium tuberculosis.
J. Mol. Biol., 430, 2018
6FW5
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TESA A MAJOR THIOESTERASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Probable thioesterase TesA, PHOSPHATE ION
Authors:Cambillau, C., Nguyen, V.S., Canaan, S.
Deposit date:2018-03-05
Release date:2018-10-24
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Biochemical and Structural Characterization of TesA, a Major Thioesterase Required for Outer-Envelope Lipid Biosynthesis in Mycobacterium tuberculosis.
J. Mol. Biol., 430, 2018